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Mus musculus

13 genes annotated in mouse

lung secretory cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lung secretory cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lung secretory cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.952
Hoxd3	homeobox D3	0.893
Hoxb5	homeobox B5	0.792	Mouse
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.751	Mouse
Gata6	GATA binding protein 6	0.655
Hoxc5	homeobox C5	0.633	Mouse
Tbx3	T-box 3	0.609
Pbx1	pre B-cell leukemia transcription factor 1	0.596
Hoxb6	homeobox B6	0.588	Mouse
Hoxa5	homeobox A5	0.581
Twist2	twist homolog 2 (Drosophila)	0.544
Fgf10	fibroblast growth factor 10	0.523
Hoxa1	homeobox A1	0.480
Gli2	GLI-Kruppel family member GLI2	0.466
Fgfr2	fibroblast growth factor receptor 2	0.440
Hoxb4	homeobox B4	0.426	Mouse
Hoxb3	homeobox B3	0.419
Zfpm2	zinc finger protein, multitype 2	0.382
Hoxa4	homeobox A4	0.360	Mouse
Pax2	paired box gene 2	0.353
Nkx2-1	NK2 homeobox 1	0.348
Gata4	GATA binding protein 4	0.302	Mouse
Hand2	heart and neural crest derivatives expressed transcript 2	0.300
Tcf21	transcription factor 21	0.296
Hoxd11	homeobox D11	0.280
Hoxa11	homeobox A11	0.273
Gata5	GATA binding protein 5	0.267	Mouse
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.220
Hoxa9	homeobox A9	0.215
Pthlh	parathyroid hormone-like peptide	0.185
Trp63	transformation related protein 63	0.183
Pitx2	paired-like homeodomain transcription factor 2	0.183
Hoxc6	homeobox C6	0.177	Mouse
Edn3	endothelin 3	0.174
Foxa2	forkhead box A2	0.170
Pitx1	paired-like homeodomain transcription factor 1	0.167
Mesp1	mesoderm posterior 1	0.161
Hoxc9	homeobox C9	0.154
Pax8	paired box gene 8	0.146
Hoxa2	homeobox A2	0.140
Rxra	retinoid X receptor alpha	0.122
Tgfb2	transforming growth factor, beta 2	0.116
Hoxc8	homeobox C8	0.115	Mouse
Egfr	epidermal growth factor receptor	0.110
Hoxa10	homeobox A10	0.110
Tgfbr3	transforming growth factor, beta receptor III	0.107
Ebf3	early B-cell factor 3	0.103
Foxf1a	forkhead box F1a	0.096
Hoxa7	homeobox A7	0.094	Mouse
Nfix	nuclear factor I/X	0.091	Mouse
Jag1	jagged 1	0.091
Sox2	SRY-box containing gene 2	0.088
Hoxd9	homeobox D9	0.086
Pdx1	pancreatic and duodenal homeobox 1	0.085
Tlx2	T-cell leukemia, homeobox 2	0.082
Fgf8	fibroblast growth factor 8	0.082
Hoxa13	homeobox A13	0.080
Hoxb2	homeobox B2	0.080
Tff1	trefoil factor 1	0.078
Gp9	glycoprotein 9 (platelet)	0.076
Sox9	SRY-box containing gene 9	0.074
Hoxc4	homeobox C4	0.072	Mouse
Hoxb9	homeobox B9	0.072
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.071	Mouse
Hoxd4	homeobox D4	0.069	Mouse
Grb10	growth factor receptor bound protein 10	0.064
Tead3	TEA domain family member 3	0.061
Sall4	sal-like 4 (Drosophila)	0.060
Klf3	Kruppel-like factor 3 (basic)	0.058
Kcnk3	potassium channel, subfamily K, member 3	0.057
Foxd2	forkhead box D2	0.057
Ntf3	neurotrophin 3	0.056
Hoxa3	homeobox A3	0.055
Hoxb8	homeobox B8	0.054	Mouse
Tacr2	tachykinin receptor 2	0.054
Hoxd8	homeobox D8	0.053	Mouse
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.053
Fgf3	fibroblast growth factor 3	0.050	Mouse
Nfia	nuclear factor I/A	0.050	Mouse
Bnc1	basonuclin 1	0.049
Hand1	heart and neural crest derivatives expressed transcript 1	0.048
Insr	insulin receptor	0.048
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.048	Mouse
Hmga2	high mobility group AT-hook 2	0.048
Nrk	Nik related kinase	0.047
Gja5	gap junction protein, alpha 5	0.047
Nkx6-1	NK6 homeobox 1	0.046
Cer1	cerberus 1 homolog (Xenopus laevis)	0.045
Isl1	ISL1 transcription factor, LIM/homeodomain	0.045
Gli3	GLI-Kruppel family member GLI3	0.044
Cfc1	cripto, FRL-1, cryptic family 1	0.044
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.043
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.043
Dhh	desert hedgehog	0.043
Meox2	mesenchyme homeobox 2	0.042
Krt14	keratin 14	0.041
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.040
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.039
Zfp503	zinc finger protein 503	0.039
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.039
Wnt2b	wingless related MMTV integration site 2b	0.039
Lmx1a	LIM homeobox transcription factor 1 alpha	0.038
Neurog3	neurogenin 3	0.038
Myog	myogenin	0.038
Bdkrb2	bradykinin receptor, beta 2	0.038
Tbx5	T-box 5	0.037
Foxb2	forkhead box B2	0.037
Hif3a	hypoxia inducible factor 3, alpha subunit	0.037
Tcf15	transcription factor 15	0.036
Tal1	T-cell acute lymphocytic leukemia 1	0.036
Tbx1	T-box 1	0.036
Tmprss2	transmembrane protease, serine 2	0.035
Gli1	GLI-Kruppel family member GLI1	0.035
Il17re	interleukin 17 receptor E	0.035
Aqp7	aquaporin 7	0.034
Efnb2	ephrin B2	0.034
Sox7	SRY-box containing gene 7	0.033
Npr3	natriuretic peptide receptor 3	0.033
Cdh3	cadherin 3	0.033
Gata3	GATA binding protein 3	0.033	Mouse
Wnt6	wingless-related MMTV integration site 6	0.032
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.032
Fgf15	fibroblast growth factor 15	0.032
Oit1	oncoprotein induced transcript 1	0.032
Grem1	gremlin 1	0.031
Tbx15	T-box 15	0.031
Wnt5a	wingless-related MMTV integration site 5A	0.031
Mdfi	MyoD family inhibitor	0.031
Barx2	BarH-like homeobox 2	0.031
Wnt11	wingless-related MMTV integration site 11	0.031
Pax3	paired box gene 3	0.030
Cldn8	claudin 8	0.030
Hoxd13	homeobox D13	0.030
Pou5f1	POU domain, class 5, transcription factor 1	0.030
Lalba	lactalbumin, alpha	0.030
Smad6	MAD homolog 6 (Drosophila)	0.030
Sfrp5	secreted frizzled-related sequence protein 5	0.030
Col2a1	collagen, type II, alpha 1	0.030
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.030
Nppc	natriuretic peptide type C	0.030
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.029
Angpt1	angiopoietin 1	0.029
Eya1	eyes absent 1 homolog (Drosophila)	0.029
En1	engrailed 1	0.029
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.029
Meis1	Meis homeobox 1	0.028
Sall3	sal-like 3 (Drosophila)	0.028
Slurp1	secreted Ly6/Plaur domain containing 1	0.028
Pitx3	paired-like homeodomain transcription factor 3	0.028
Lhx3	LIM homeobox protein 3	0.028
Rab25	RAB25, member RAS oncogene family	0.028
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.027
Axin2	axin2	0.027
Agrp	agouti related protein	0.026
Fndc7	fibronectin type III domain containing 7	0.026
Adra2b	adrenergic receptor, alpha 2b	0.026
Sim1	single-minded homolog 1 (Drosophila)	0.025
Pax9	paired box gene 9	0.025
Fut2	fucosyltransferase 2	0.025
Pou3f3	POU domain, class 3, transcription factor 3	0.025
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.024
Hoxd10	homeobox D10	0.024
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.024	Mouse
Otp	orthopedia homolog (Drosophila)	0.024
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.024	Mouse
Gdnf	glial cell line derived neurotrophic factor	0.024
Fgfbp1	fibroblast growth factor binding protein 1	0.024
Nog	noggin	0.024
Alx3	aristaless-like homeobox 3	0.024
Barx1	BarH-like homeobox 1	0.023
Hmx3	H6 homeobox 3	0.023
Ptprd	protein tyrosine phosphatase, receptor type, D	0.023
Tbx20	T-box 20	0.023
Atoh7	atonal homolog 7 (Drosophila)	0.023
Igf1r	insulin-like growth factor I receptor	0.023
Ctf1	cardiotrophin 1	0.023
Slc25a48	solute carrier family 25, member 48	0.023
Irx5	Iroquois related homeobox 5 (Drosophila)	0.023
Uncx	UNC homeobox	0.022
Nfic	nuclear factor I/C	0.022	Mouse
Wt1	Wilms tumor 1 homolog	0.022
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.022
Ppara	peroxisome proliferator activated receptor alpha	0.021
Fgf9	fibroblast growth factor 9	0.021	Mouse
Socs1	suppressor of cytokine signaling 1	0.021
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.021
Foxe1	forkhead box E1	0.021
Irx3	Iroquois related homeobox 3 (Drosophila)	0.021
Sstr4	somatostatin receptor 4	0.021
Phox2b	paired-like homeobox 2b	0.020
Krt15	keratin 15	0.020
Epha1	Eph receptor A1	0.020
B4galnt2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.020
Sim2	single-minded homolog 2 (Drosophila)	0.020
Ehf	ets homologous factor	0.020	Mouse
Rgnef	Rho-guanine nucleotide exchange factor	0.020
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.020
Sox3	SRY-box containing gene 3	0.020
Alppl2	alkaline phosphatase, placental-like 2	0.020
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.019
Nfib	nuclear factor I/B	0.019
Ihh	Indian hedgehog	0.019
Sox13	SRY-box containing gene 13	0.019
Evx2	even skipped homeotic gene 2 homolog	0.019
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.019
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.019
Mecom	MDS1 and EVI1 complex locus	0.019
Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3	0.018
Elf4	E74-like factor 4 (ets domain transcription factor)	0.018	Mouse
Gjb4	gap junction protein, beta 4	0.018
Efnb1	ephrin B1	0.018
Gh	growth hormone	0.018
Efna4	ephrin A4	0.018
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.018
Tssk1	testis-specific serine kinase 1	0.018
Avpr2	arginine vasopressin receptor 2	0.018
Tbx2	T-box 2	0.018
Guca2b	guanylate cyclase activator 2b (retina)	0.018
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.018
Cdh16	cadherin 16	0.018
Fgf4	fibroblast growth factor 4	0.018	Mouse
Ins2	insulin II	0.017	Mouse
Gata2	GATA binding protein 2	0.017	Mouse
Fgf18	fibroblast growth factor 18	0.017
Myod1	myogenic differentiation 1	0.017
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.017
Tcfap2c	transcription factor AP-2, gamma	0.017
Hist1h1t	histone cluster 1, H1t	0.017
Ly6g6c	lymphocyte antigen 6 complex, locus G6C	0.017
Angpt4	angiopoietin 4	0.016
Erbb2ip	Erbb2 interacting protein	0.016
Tecta	tectorin alpha	0.016
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.016
Sox4	SRY-box containing gene 4	0.016
Tcfap2b	transcription factor AP-2 beta	0.016
Adra2a	adrenergic receptor, alpha 2a	0.016
Hmx1	H6 homeobox 1	0.016
Ikzf1	IKAROS family zinc finger 1	0.016
Tcfap2a	transcription factor AP-2, alpha	0.016
Foxd3	forkhead box D3	0.016
Foxa1	forkhead box A1	0.015
She	src homology 2 domain-containing transforming protein E	0.015
Jak2	Janus kinase 2	0.015
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.015
Bmp8b	bone morphogenetic protein 8b	0.015
Zfp185	zinc finger protein 185	0.015
Hr	hairless	0.015
Foxn1	forkhead box N1	0.015
Srcin1	SRC kinase signaling inhibitor 1	0.015
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.015
Cel	carboxyl ester lipase	0.015
Vax1	ventral anterior homeobox containing gene 1	0.015
Hoxb1	homeobox B1	0.015
Zbtb20	zinc finger and BTB domain containing 20	0.015
Fgf5	fibroblast growth factor 5	0.015	Mouse
Emx2	empty spiracles homolog 2 (Drosophila)	0.015
Clcnka	chloride channel Ka	0.014
Adam17	a disintegrin and metallopeptidase domain 17	0.014
Hnf4a	hepatic nuclear factor 4, alpha	0.014
Pcdh12	protocadherin 12	0.014
Epha4	Eph receptor A4	0.014
Mgat3	mannoside acetylglucosaminyltransferase 3	0.014
Krt35	keratin 35	0.014
Zfp362	zinc finger protein 362	0.014
Ghr	growth hormone receptor	0.014
Cdh15	cadherin 15	0.014
Notch1	Notch gene homolog 1 (Drosophila)	0.014
Foxd1	forkhead box D1	0.014
Padi1	peptidyl arginine deiminase, type I	0.014
Ins1	insulin I	0.014	Mouse
Hic1	hypermethylated in cancer 1	0.014
Gpc3	glypican 3	0.013
Rara	retinoic acid receptor, alpha	0.013
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.013
Thrb	thyroid hormone receptor beta	0.013
Meis2	Meis homeobox 2	0.013
Vipr2	vasoactive intestinal peptide receptor 2	0.013
Nrtn	neurturin	0.013
Fzd8	frizzled homolog 8 (Drosophila)	0.013
Insm1	insulinoma-associated 1	0.013
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.013
Zfhx3	zinc finger homeobox 3	0.013
Myl7	myosin, light polypeptide 7, regulatory	0.013
Sftpb	surfactant associated protein B	0.013
Zan	zonadhesin	0.013
Duox2	dual oxidase 2	0.013
Foxc2	forkhead box C2	0.013
Sycn	syncollin	0.013
Tbx10	T-box 10	0.013
Nynrin	NYN domain and retroviral integrase containing	0.013
Prr15	proline rich 15	0.013
Sstr5	somatostatin receptor 5	0.013
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.013
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.012
Smad4	MAD homolog 4 (Drosophila)	0.012
Rarb	retinoic acid receptor, beta	0.012
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.012
Tgm3	transglutaminase 3, E polypeptide	0.012
Omp	olfactory marker protein	0.012
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.012
Fzd4	frizzled homolog 4 (Drosophila)	0.012
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.012
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.012
Evx1	even skipped homeotic gene 1 homolog	0.012
Gm13290	predicted gene 13290	0.012
Prdm6	PR domain containing 6	0.012
Prf1	perforin 1 (pore forming protein)	0.012
Prox1	prospero-related homeobox 1	0.012
Moxd2	monooxygenase, DBH-like 2	0.012
Capn9	calpain 9	0.012
Msx2	homeobox, msh-like 2	0.012
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.012
Galr3	galanin receptor 3	0.012
Nhlh1	nescient helix loop helix 1	0.011
Chd7	chromodomain helicase DNA binding protein 7	0.011
Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	0.011
Th	tyrosine hydroxylase	0.011
Ar	androgen receptor	0.011
BC018465	cDNA sequence BC018465	0.011
Fzd6	frizzled homolog 6 (Drosophila)	0.011
Cldn4	claudin 4	0.011
Shox2	short stature homeobox 2	0.011
Fev	FEV (ETS oncogene family)	0.011
BC057022	cDNA sequence BC057022	0.011
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.011
1600029D21Rik	RIKEN cDNA 1600029D21 gene	0.011
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.011
Zfpm1	zinc finger protein, multitype 1	0.011
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.011
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.011
Foxb1	forkhead box B1	0.011
Upk3b	uroplakin 3B	0.011
Epha3	Eph receptor A3	0.011
Klk4	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	0.011
Nefm	neurofilament, medium polypeptide	0.011
Tff2	trefoil factor 2 (spasmolytic protein 1)	0.011
Dlk1	delta-like 1 homolog (Drosophila)	0.010
Plac1	placental specific protein 1	0.010
Pgr	progesterone receptor	0.010
Cldn7	claudin 7	0.010
Fzd7	frizzled homolog 7 (Drosophila)	0.010
Tcf4	transcription factor 4	0.010
Krt13	keratin 13	0.010
Gjb5	gap junction protein, beta 5	0.010
Hhex	hematopoietically expressed homeobox	0.010
Pkdcc	protein kinase domain containing, cytoplasmic	0.010
Snai1	snail homolog 1 (Drosophila)	0.010
Pou3f4	POU domain, class 3, transcription factor 4	0.010
Myoz1	myozenin 1	0.010
Lama3	laminin, alpha 3	0.010