IMP

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Mus musculus

15 genes annotated in mouse

regulation of metanephros development

Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of metanephros development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of metanephros development" (in gray)

Name	Description	Probability	Func Analog Organism
Ret	ret proto-oncogene	0.992
Vegfa	vascular endothelial growth factor A	0.985
Nos3	nitric oxide synthase 3, endothelial cell	0.980
Pax2	paired box gene 2	0.965
Lhx1	LIM homeobox protein 1	0.916
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.866	Mouse
Ren1	renin 1 structural	0.864
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.767
Gdnf	glial cell line derived neurotrophic factor	0.720
Fgf8	fibroblast growth factor 8	0.633
Bcl2	B-cell leukemia/lymphoma 2	0.572
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.570
Wnt4	wingless-related MMTV integration site 4	0.517	Mouse
Emx2	empty spiracles homolog 2 (Drosophila)	0.465
Sall4	sal-like 4 (Drosophila)	0.464	Mouse
Pax8	paired box gene 8	0.437
Ptgs2	prostaglandin-endoperoxide synthase 2	0.407
Lama5	laminin, alpha 5	0.398
C1qc	complement component 1, q subcomponent, C chain	0.390	Mouse
C1qb	complement component 1, q subcomponent, beta polypeptide	0.376	Mouse
Foxc2	forkhead box C2	0.344
T	brachyury	0.337
Bdkrb2	bradykinin receptor, beta 2	0.325	Mouse
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.316
Fgfr2	fibroblast growth factor receptor 2	0.311
Lmx1a	LIM homeobox transcription factor 1 alpha	0.307
Shh	sonic hedgehog	0.291
Sall1	sal-like 1 (Drosophila)	0.246
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.242
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.241
Hoxd11	homeobox D11	0.240
Kdr	kinase insert domain protein receptor	0.229	Mouse
Lepr	leptin receptor	0.202
Rara	retinoic acid receptor, alpha	0.197
Fgfr1	fibroblast growth factor receptor 1	0.196
Tbx1	T-box 1	0.195
Fos	FBJ osteosarcoma oncogene	0.192
Rarb	retinoic acid receptor, beta	0.184
Tyrobp	TYRO protein tyrosine kinase binding protein	0.180
Gli3	GLI-Kruppel family member GLI3	0.169
Wnt9b	wingless-type MMTV integration site 9B	0.165
Rarg	retinoic acid receptor, gamma	0.162
Yap1	yes-associated protein 1	0.159
Ptprb	protein tyrosine phosphatase, receptor type, B	0.159
Trp53	transformation related protein 53	0.157
Gli2	GLI-Kruppel family member GLI2	0.151
Agtr1a	angiotensin II receptor, type 1a	0.148	Mouse
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.144
Wt1	Wilms tumor 1 homolog	0.143
Ednrb	endothelin receptor type B	0.140
Fgf3	fibroblast growth factor 3	0.134
Msx1	homeobox, msh-like 1	0.125
Vax1	ventral anterior homeobox containing gene 1	0.124
Hoxa11	homeobox A11	0.121
Nog	noggin	0.116
Wnt6	wingless-related MMTV integration site 6	0.113	Mouse
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.111
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.108
Hoxa1	homeobox A1	0.106
Wwtr1	WW domain containing transcription regulator 1	0.104
Jun	Jun oncogene	0.099
Sox10	SRY-box containing gene 10	0.093
Foxd2	forkhead box D2	0.089
Foxc1	forkhead box C1	0.083
Alx3	aristaless-like homeobox 3	0.081
Otx1	orthodenticle homolog 1 (Drosophila)	0.079
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.077
Pitx3	paired-like homeodomain transcription factor 3	0.074
Flt4	FMS-like tyrosine kinase 4	0.073	Mouse
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.072
Tbx2	T-box 2	0.070
Phox2b	paired-like homeobox 2b	0.068
Pou5f1	POU domain, class 5, transcription factor 1	0.065
Gbx2	gastrulation brain homeobox 2	0.063
Sox7	SRY-box containing gene 7	0.062
Pax3	paired box gene 3	0.060
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.060
Csf1r	colony stimulating factor 1 receptor	0.059	Mouse
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.057
Ldlr	low density lipoprotein receptor	0.056
Sall3	sal-like 3 (Drosophila)	0.056	Mouse
Osr1	odd-skipped related 1 (Drosophila)	0.055
Nos2	nitric oxide synthase 2, inducible	0.055
Trp73	transformation related protein 73	0.054
Wnt10b	wingless related MMTV integration site 10b	0.054	Mouse
Hoxa3	homeobox A3	0.053
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.053
Nos1	nitric oxide synthase 1, neuronal	0.053
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.052
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.050
Bmp4	bone morphogenetic protein 4	0.050	Human
Hmx3	H6 homeobox 3	0.049
Tead3	TEA domain family member 3	0.048
Ctnnb1	catenin (cadherin associated protein), beta 1	0.046
Csf1	colony stimulating factor 1 (macrophage)	0.046
Bmp7	bone morphogenetic protein 7	0.046
Tnfrsf8	tumor necrosis factor receptor superfamily, member 8	0.045
Foxf1a	forkhead box F1a	0.045
Npas1	neuronal PAS domain protein 1	0.043
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.043
Ar	androgen receptor	0.043
Notch2	Notch gene homolog 2 (Drosophila)	0.043
Wnt3a	wingless-related MMTV integration site 3A	0.042	Mouse
Zic2	zinc finger protein of the cerebellum 2	0.042
Vhl	von Hippel-Lindau tumor suppressor	0.042
Csf3	colony stimulating factor 3 (granulocyte)	0.042
Gucy2e	guanylate cyclase 2e	0.042
Tgfb1	transforming growth factor, beta 1	0.041
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.041
Amhr2	anti-Mullerian hormone type 2 receptor	0.041
Sox4	SRY-box containing gene 4	0.040
Lef1	lymphoid enhancer binding factor 1	0.040
Adra2b	adrenergic receptor, alpha 2b	0.038
Ly86	lymphocyte antigen 86	0.038
Wnt10a	wingless related MMTV integration site 10a	0.038
Col4a3	collagen, type IV, alpha 3	0.037
Pou3f1	POU domain, class 3, transcription factor 1	0.037
Artn	artemin	0.037	Mouse
Neurog1	neurogenin 1	0.036
Phox2a	paired-like homeobox 2a	0.036
Efna4	ephrin A4	0.035
Ntf3	neurotrophin 3	0.035
Foxa2	forkhead box A2	0.035
Ptch1	patched homolog 1	0.034
Max	Max protein	0.034
Acvr1	activin A receptor, type 1	0.034
Bmper	BMP-binding endothelial regulator	0.034
Tcf21	transcription factor 21	0.033
Cdx1	caudal type homeobox 1	0.032
Tgfbr2	transforming growth factor, beta receptor II	0.032
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.032
Pcdh12	protocadherin 12	0.032
Vegfc	vascular endothelial growth factor C	0.031
Acan	aggrecan	0.030
Hoxb3	homeobox B3	0.030
Wnt2b	wingless related MMTV integration site 2b	0.028	Mouse
Rsph6a	radial spoke head 6 homolog A (Chlamydomonas)	0.027
Amh	anti-Mullerian hormone	0.026
Gli1	GLI-Kruppel family member GLI1	0.026
Nkx6-1	NK6 homeobox 1	0.026
Gas1	growth arrest specific 1	0.026
Gpr27	G protein-coupled receptor 27	0.026
Dchs1	dachsous 1 (Drosophila)	0.025
Ctss	cathepsin S	0.025
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.025	Mouse
Lhx9	LIM homeobox protein 9	0.025
Fzd4	frizzled homolog 4 (Drosophila)	0.025
Isl1	ISL1 transcription factor, LIM/homeodomain	0.025
Foxd3	forkhead box D3	0.024
Aqp2	aquaporin 2	0.024
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.024
Wnt9a	wingless-type MMTV integration site 9A	0.024	Mouse
Vangl2	vang-like 2 (van gogh, Drosophila)	0.024
Ephb2	Eph receptor B2	0.023
Itga3	integrin alpha 3	0.023
Igl	immunoglobulin lambda chain complex	0.023
Fbn1	fibrillin 1	0.022
Hoxd9	homeobox D9	0.022
Foxf2	forkhead box F2	0.022
Zeb1	zinc finger E-box binding homeobox 1	0.022
Tead2	TEA domain family member 2	0.021
Tacr1	tachykinin receptor 1	0.021
Sox1	SRY-box containing gene 1	0.021
Prrx2	paired related homeobox 2	0.021
Tlx2	T-cell leukemia, homeobox 2	0.021
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.021
Fgf15	fibroblast growth factor 15	0.021
Hoxa2	homeobox A2	0.021
Aif1	allograft inflammatory factor 1	0.021
Lyzl4	lysozyme-like 4	0.021
Vstm2b	V-set and transmembrane domain containing 2B	0.020
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.020
Grik3	glutamate receptor, ionotropic, kainate 3	0.020
Meox2	mesenchyme homeobox 2	0.020
Smo	smoothened homolog (Drosophila)	0.020
Calcb	calcitonin-related polypeptide, beta	0.020
Rnf208	ring finger protein 208	0.020
Hand1	heart and neural crest derivatives expressed transcript 1	0.020
Pgr	progesterone receptor	0.020
Cav1	caveolin 1, caveolae protein	0.020
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.020
Nodal	nodal	0.019
Wnt5a	wingless-related MMTV integration site 5A	0.019	Mouse
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.019
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.019
Olfr70	olfactory receptor 70	0.019
Adra2a	adrenergic receptor, alpha 2a	0.019
Pou3f2	POU domain, class 3, transcription factor 2	0.019
Mybpc3	myosin binding protein C, cardiac	0.019
Plxnd1	plexin D1	0.018
Bnc1	basonuclin 1	0.018
Ednra	endothelin receptor type A	0.018
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.018
Col13a1	collagen, type XIII, alpha 1	0.018
Otx2	orthodenticle homolog 2 (Drosophila)	0.018
Efna2	ephrin A2	0.017
Col14a1	collagen, type XIV, alpha 1	0.016
Ptk7	PTK7 protein tyrosine kinase 7	0.016
Kitl	kit ligand	0.016
Mrc1	mannose receptor, C type 1	0.016
Hoxb6	homeobox B6	0.016
Foxe3	forkhead box E3	0.016
Omp	olfactory marker protein	0.016
Robo3	roundabout homolog 3 (Drosophila)	0.016
Cabp7	calcium binding protein 7	0.016
Hmx1	H6 homeobox 1	0.015
Hnf1a	HNF1 homeobox A	0.015	Mouse
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.015
Bicc1	bicaudal C homolog 1 (Drosophila)	0.015
Foxb2	forkhead box B2	0.015
Dlx4	distal-less homeobox 4	0.015
Pou4f2	POU domain, class 4, transcription factor 2	0.015
Foxb1	forkhead box B1	0.015
Grem1	gremlin 1	0.015
Gata6	GATA binding protein 6	0.015
Fgf5	fibroblast growth factor 5	0.015
Tmem204	transmembrane protein 204	0.015
En1	engrailed 1	0.015
Neurog3	neurogenin 3	0.015
Gpr3	G-protein coupled receptor 3	0.014
Bcl6b	B-cell CLL/lymphoma 6, member B	0.014
Fgf17	fibroblast growth factor 17	0.014
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.014
Cxcl12	chemokine (C-X-C motif) ligand 12	0.013
Ngf	nerve growth factor	0.013
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.013
Otog	otogelin	0.013
Twist2	twist homolog 2 (Drosophila)	0.013
Bmp2	bone morphogenetic protein 2	0.013
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.013
Icam5	intercellular adhesion molecule 5, telencephalin	0.013
Sox9	SRY-box containing gene 9	0.013
Irx4	Iroquois related homeobox 4 (Drosophila)	0.013
P2rx6	purinergic receptor P2X, ligand-gated ion channel, 6	0.013
Fxyd2	FXYD domain-containing ion transport regulator 2	0.013
Nrp1	neuropilin 1	0.013
Dlx2	distal-less homeobox 2	0.013
Lhx3	LIM homeobox protein 3	0.013
Sp5	trans-acting transcription factor 5	0.013
Barx1	BarH-like homeobox 1	0.013
Irx1	Iroquois related homeobox 1 (Drosophila)	0.013
Col22a1	collagen, type XXII, alpha 1	0.013
Fgf23	fibroblast growth factor 23	0.012
Ctnnd1	catenin (cadherin associated protein), delta 1	0.012
Ahr	aryl-hydrocarbon receptor	0.012
Tead1	TEA domain family member 1	0.012
Rem1	rad and gem related GTP binding protein 1	0.012
Tnni2	troponin I, skeletal, fast 2	0.012
Tacr2	tachykinin receptor 2	0.012
Foxl2	forkhead box L2	0.012
Fosl2	fos-like antigen 2	0.012
Papln	papilin, proteoglycan-like sulfated glycoprotein	0.012
Rax	retina and anterior neural fold homeobox	0.012
Nf1	neurofibromatosis 1	0.012
Grhl2	grainyhead-like 2 (Drosophila)	0.012
Gpr50	G-protein-coupled receptor 50	0.012
Alx4	aristaless-like homeobox 4	0.012
Grin2c	glutamate receptor, ionotropic, NMDA2C (epsilon 3)	0.012
Il11	interleukin 11	0.012
Scube1	signal peptide, CUB domain, EGF-like 1	0.012
Hoxa7	homeobox A7	0.012
Fbln1	fibulin 1	0.011
Pld4	phospholipase D family, member 4	0.011
Foxd4	forkhead box D4	0.011
Inhbb	inhibin beta-B	0.011
Otof	otoferlin	0.011
Foxi1	forkhead box I1	0.011
Lmx1b	LIM homeobox transcription factor 1 beta	0.011
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.011	Mouse
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.011
Krtdap	keratinocyte differentiation associated protein	0.011
Ghrhr	growth hormone releasing hormone receptor	0.011
Fzd10	frizzled homolog 10 (Drosophila)	0.011
Egr3	early growth response 3	0.011	Mouse
Uncx	UNC homeobox	0.011
BC021891	cDNA sequence BC021891	0.011
Prss39	protease, serine, 39	0.011
Efnb1	ephrin B1	0.011
Cabp2	calcium binding protein 2	0.011
Dlx5	distal-less homeobox 5	0.011
Phf19	PHD finger protein 19	0.011
Crlf1	cytokine receptor-like factor 1	0.010
Zfp771	zinc finger protein 771	0.010
Gjc2	gap junction protein, gamma 2	0.010
Lamc1	laminin, gamma 1	0.010
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.010
Fzd8	frizzled homolog 8 (Drosophila)	0.010
Glis2	GLIS family zinc finger 2	0.010
Cyp11b2	cytochrome P450, family 11, subfamily b, polypeptide 2	0.010
Folr2	folate receptor 2 (fetal)	0.010
Sim2	single-minded homolog 2 (Drosophila)	0.010
Kiss1	KiSS-1 metastasis-suppressor	0.010
Fgf4	fibroblast growth factor 4	0.010
Prima1	proline rich membrane anchor 1	0.010
Dmrt3	doublesex and mab-3 related transcription factor 3	0.010
Dlg1	discs, large homolog 1 (Drosophila)	0.010
Gdf11	growth differentiation factor 11	0.010
Gipc3	GIPC PDZ domain containing family, member 3	0.010
Kl	klotho	0.010
5730559C18Rik	RIKEN cDNA 5730559C18 gene	0.010