IMP

Process View

Mus musculus

2 genes annotated in mouse

wnt signaling pathway involved in kidney development

The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "wnt signaling pathway involved in kidney development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "wnt signaling pathway involved in kidney development" (in gray)

Name	Description	Probability	Func Analog Organism
Esr1	estrogen receptor 1 (alpha)	1.000
Ar	androgen receptor	0.998
Gata6	GATA binding protein 6	0.996	Mouse
Pitx2	paired-like homeodomain transcription factor 2	0.995
Pax8	paired box gene 8	0.992
Rxra	retinoid X receptor alpha	0.983
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.975	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.967
Gata4	GATA binding protein 4	0.966	Mouse
Fshr	follicle stimulating hormone receptor	0.947	Mouse
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.938
Pax2	paired box gene 2	0.892
Bmp4	bone morphogenetic protein 4	0.891
Nos3	nitric oxide synthase 3, endothelial cell	0.819
Pten	phosphatase and tensin homolog	0.816
Jag1	jagged 1	0.815
Fgf10	fibroblast growth factor 10	0.803
Ghr	growth hormone receptor	0.773
Tgfb2	transforming growth factor, beta 2	0.756
Foxc1	forkhead box C1	0.752
Hoxa1	homeobox A1	0.734
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.730
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.698
Zfpm2	zinc finger protein, multitype 2	0.670
Tbx3	T-box 3	0.635
Vegfa	vascular endothelial growth factor A	0.633
Thrb	thyroid hormone receptor beta	0.595
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.471
Kiss1	KiSS-1 metastasis-suppressor	0.449
Foxc2	forkhead box C2	0.441
Amhr2	anti-Mullerian hormone type 2 receptor	0.410
Wt1	Wilms tumor 1 homolog	0.379
Gli3	GLI-Kruppel family member GLI3	0.376
Chd7	chromodomain helicase DNA binding protein 7	0.374
Gata5	GATA binding protein 5	0.341	Mouse
Lepr	leptin receptor	0.335
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.332
Shh	sonic hedgehog	0.308
Egfr	epidermal growth factor receptor	0.299
Inha	inhibin alpha	0.296
Inhba	inhibin beta-A	0.292
Lep	leptin	0.285
Adam17	a disintegrin and metallopeptidase domain 17	0.272
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.257
Foxf2	forkhead box F2	0.256
Tead3	TEA domain family member 3	0.247
Bnc1	basonuclin 1	0.230
Hoxa10	homeobox A10	0.224
Fgf8	fibroblast growth factor 8	0.218
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.207
Foxf1a	forkhead box F1a	0.196
Hand2	heart and neural crest derivatives expressed transcript 2	0.195
Irs2	insulin receptor substrate 2	0.192
Tal1	T-cell acute lymphocytic leukemia 1	0.174
Ppara	peroxisome proliferator activated receptor alpha	0.171
Bglap	bone gamma carboxyglutamate protein	0.168
Kit	kit oncogene	0.168
Rarg	retinoic acid receptor, gamma	0.144
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.143
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.135
Kiss1r	KISS1 receptor	0.134
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.127
Prlr	prolactin receptor	0.127
Bcl2	B-cell leukemia/lymphoma 2	0.124
Sox7	SRY-box containing gene 7	0.120
Hoxc8	homeobox C8	0.118
Npr1	natriuretic peptide receptor 1	0.115
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.113
Gnrh1	gonadotropin releasing hormone 1	0.110
Smad6	MAD homolog 6 (Drosophila)	0.104
Notch1	Notch gene homolog 1 (Drosophila)	0.103
Meox2	mesenchyme homeobox 2	0.099
Tbx1	T-box 1	0.099
Eya1	eyes absent 1 homolog (Drosophila)	0.098
Mesp1	mesoderm posterior 1	0.098
Duox2	dual oxidase 2	0.093
Hoxa2	homeobox A2	0.092
Klf3	Kruppel-like factor 3 (basic)	0.091
Isl1	ISL1 transcription factor, LIM/homeodomain	0.091
Plac1	placental specific protein 1	0.089
Thra	thyroid hormone receptor alpha	0.079
Tcf21	transcription factor 21	0.078
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.078
Tbx2	T-box 2	0.076
Sox9	SRY-box containing gene 9	0.071
Rarb	retinoic acid receptor, beta	0.071
Rb1	retinoblastoma 1	0.061
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.054
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.054
Hoxb4	homeobox B4	0.053
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.053
Apc	adenomatosis polyposis coli	0.052
Igf1	insulin-like growth factor 1	0.048
Gdnf	glial cell line derived neurotrophic factor	0.048
Ctnnb1	catenin (cadherin associated protein), beta 1	0.047
Myl7	myosin, light polypeptide 7, regulatory	0.046
Ntf3	neurotrophin 3	0.046
Hoxd13	homeobox D13	0.045
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.045
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.044
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.043
Efna4	ephrin A4	0.043
Esr2	estrogen receptor 2 (beta)	0.043
Casq1	calsequestrin 1	0.042
Ppl	periplakin	0.042
Sox4	SRY-box containing gene 4	0.042
Twist2	twist homolog 2 (Drosophila)	0.042
Trp53	transformation related protein 53	0.042
Des	desmin	0.041
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.040
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.040
Lef1	lymphoid enhancer binding factor 1	0.040
S1pr2	sphingosine-1-phosphate receptor 2	0.039
Dll1	delta-like 1 (Drosophila)	0.039
Ihh	Indian hedgehog	0.038
Vdr	vitamin D receptor	0.038
Myo6	myosin VI	0.037
Gja1	gap junction protein, alpha 1	0.035
Gpr50	G-protein-coupled receptor 50	0.035
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.035
Nrk	Nik related kinase	0.034
BC020535	cDNA sequence BC020535	0.034
Snai1	snail homolog 1 (Drosophila)	0.034
Efnb2	ephrin B2	0.034
Podxl	podocalyxin-like	0.032
Tbx20	T-box 20	0.032
Hoxb3	homeobox B3	0.032
Hoxa11	homeobox A11	0.032
Hand1	heart and neural crest derivatives expressed transcript 1	0.030
Nf1	neurofibromatosis 1	0.030
Mecom	MDS1 and EVI1 complex locus	0.030
Star	steroidogenic acute regulatory protein	0.030
Bglap2	bone gamma-carboxyglutamate protein 2	0.030
Stc2	stanniocalcin 2	0.029
Gpc3	glypican 3	0.028
Ahr	aryl-hydrocarbon receptor	0.028
Fzd4	frizzled homolog 4 (Drosophila)	0.028
Sim2	single-minded homolog 2 (Drosophila)	0.027
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.026
Alox12	arachidonate 12-lipoxygenase	0.025
Vangl2	vang-like 2 (van gogh, Drosophila)	0.025
Sult5a1	sulfotransferase family 5A, member 1	0.025
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.024
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.024
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.024
Emx2	empty spiracles homolog 2 (Drosophila)	0.024
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.024
Zfpm1	zinc finger protein, multitype 1	0.024
Efnb1	ephrin B1	0.024
Lhx3	LIM homeobox protein 3	0.024
Hoxa4	homeobox A4	0.024
Gypa	glycophorin A	0.024
She	src homology 2 domain-containing transforming protein E	0.023
Upk3b	uroplakin 3B	0.023
Tbx5	T-box 5	0.023
Zeb1	zinc finger E-box binding homeobox 1	0.022
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.022
Dhh	desert hedgehog	0.022
Rara	retinoic acid receptor, alpha	0.021
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.021
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.021
Fbn2	fibrillin 2	0.021
Tshr	thyroid stimulating hormone receptor	0.020	Mouse
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.020
Zfp185	zinc finger protein 185	0.020
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.020
Epha1	Eph receptor A1	0.019
Hoxd10	homeobox D10	0.019
Ctf1	cardiotrophin 1	0.019
Hic1	hypermethylated in cancer 1	0.019
Slc38a5	solute carrier family 38, member 5	0.019
Neurog3	neurogenin 3	0.019
Brca2	breast cancer 2	0.019
Hoxb6	homeobox B6	0.018
Gata2	GATA binding protein 2	0.018	Mouse
Inhbb	inhibin beta-B	0.018
Inca1	inhibitor of CDK, cyclin A1 interacting protein 1	0.018
Nynrin	NYN domain and retroviral integrase containing	0.018
Lhx9	LIM homeobox protein 9	0.018
Gbx2	gastrulation brain homeobox 2	0.018
Wwox	WW domain-containing oxidoreductase	0.018
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.018
Wnt4	wingless-related MMTV integration site 4	0.018
Hmga2	high mobility group AT-hook 2	0.017
Amh	anti-Mullerian hormone	0.017
Spo11	sporulation protein, meiosis-specific, SPO11 homolog (S. cerevisiae)	0.017
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.017
Tead1	TEA domain family member 1	0.017
Tbxa2r	thromboxane A2 receptor	0.017
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.017
Axin2	axin2	0.017
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.017
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.017
Hoxd9	homeobox D9	0.017
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.017
Gpr97	G protein-coupled receptor 97	0.016
Fst	follistatin	0.016
Ret	ret proto-oncogene	0.016
Tmprss2	transmembrane protease, serine 2	0.016
Myb	myeloblastosis oncogene	0.016
Bcl6b	B-cell CLL/lymphoma 6, member B	0.016
Efna5	ephrin A5	0.016
Gata1	GATA binding protein 1	0.016	Mouse
Col4a3	collagen, type IV, alpha 3	0.016
Fzd8	frizzled homolog 8 (Drosophila)	0.015
Gab2	growth factor receptor bound protein 2-associated protein 2	0.015
Ednra	endothelin receptor type A	0.015
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.015
Hoxd8	homeobox D8	0.015
Lrp2	low density lipoprotein receptor-related protein 2	0.015
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.015
Tbx4	T-box 4	0.014
Tac2	tachykinin 2	0.014
Cldn8	claudin 8	0.014
Fgf18	fibroblast growth factor 18	0.014
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.014
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.014
Creb3l1	cAMP responsive element binding protein 3-like 1	0.014
Ank1	ankyrin 1, erythroid	0.014
Apln	apelin	0.013
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.013
Tg	thyroglobulin	0.013
T	brachyury	0.013
Bmp7	bone morphogenetic protein 7	0.013
Tcfap2a	transcription factor AP-2, alpha	0.013
Foxa3	forkhead box A3	0.013
Epha2	Eph receptor A2	0.013
Rdh10	retinol dehydrogenase 10 (all-trans)	0.013
Mfsd7c	major facilitator superfamily domain containing 7C	0.013
Plekha5	pleckstrin homology domain containing, family A member 5	0.013
Hoxb5	homeobox B5	0.013
Zfp503	zinc finger protein 503	0.013
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.012
Tert	telomerase reverse transcriptase	0.012
Smad4	MAD homolog 4 (Drosophila)	0.012
Smad3	MAD homolog 3 (Drosophila)	0.012
Hoxa13	homeobox A13	0.012
Npc1	Niemann Pick type C1	0.012
Irx5	Iroquois related homeobox 5 (Drosophila)	0.012
Trp63	transformation related protein 63	0.012
Nr6a1	nuclear receptor subfamily 6, group A, member 1	0.012
Obsl1	obscurin-like 1	0.012
Fancl	Fanconi anemia, complementation group L	0.012
Hoxa5	homeobox A5	0.012
Lmx1a	LIM homeobox transcription factor 1 alpha	0.012
Mogat2	monoacylglycerol O-acyltransferase 2	0.012
Irx3	Iroquois related homeobox 3 (Drosophila)	0.012
Rhag	Rhesus blood group-associated A glycoprotein	0.012
Nfia	nuclear factor I/A	0.011
Lhx1	LIM homeobox protein 1	0.011
Gata3	GATA binding protein 3	0.011
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.011
Gja4	gap junction protein, alpha 4	0.011
Npr3	natriuretic peptide receptor 3	0.011
Baiap2l1	BAI1-associated protein 2-like 1	0.011
Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1	0.011
Foxg1	forkhead box G1	0.011
Dll4	delta-like 4 (Drosophila)	0.011
Foxa1	forkhead box A1	0.011
Mmp11	matrix metallopeptidase 11	0.011
Hoxc4	homeobox C4	0.011
Gli2	GLI-Kruppel family member GLI2	0.011
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.011
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.011
Gja5	gap junction protein, alpha 5	0.010
Drd2	dopamine receptor D2	0.010
Gfi1b	growth factor independent 1B	0.010
Sox17	SRY-box containing gene 17	0.010
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.010
Hes1	hairy and enhancer of split 1 (Drosophila)	0.010
Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	0.010
Insr	insulin receptor	0.010
Pparg	peroxisome proliferator activated receptor gamma	0.010
Wnt2b	wingless related MMTV integration site 2b	0.010
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.010
Pax3	paired box gene 3	0.010
Fgfr3	fibroblast growth factor receptor 3	0.010
Psg17	pregnancy specific glycoprotein 17	0.010