IMP

Process View

Mus musculus

11 genes annotated in mouse

cell fate specification involved in pattern specification

The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell fate specification involved in pattern specification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cell fate specification involved in pattern specification" (in gray)

Name	Description	Probability	Func Analog Organism
Gli3	GLI-Kruppel family member GLI3	1.000
Otx2	orthodenticle homolog 2 (Drosophila)	1.000
Shh	sonic hedgehog	1.000
Pax6	paired box gene 6	0.990
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.985	Worm
Pax2	paired box gene 2	0.979
Vangl2	vang-like 2 (van gogh, Drosophila)	0.927
Pitx2	paired-like homeodomain transcription factor 2	0.920
Emx1	empty spiracles homolog 1 (Drosophila)	0.909
Gli2	GLI-Kruppel family member GLI2	0.908
Fgf8	fibroblast growth factor 8	0.886
Emx2	empty spiracles homolog 2 (Drosophila)	0.867
Pax3	paired box gene 3	0.844
Lhx5	LIM homeobox protein 5	0.829	Mouse
Sox2	SRY-box containing gene 2	0.829
Hoxd3	homeobox D3	0.797	Mouse
Isl1	ISL1 transcription factor, LIM/homeodomain	0.796	Mouse Fly
Gbx2	gastrulation brain homeobox 2	0.765
Vangl1	vang-like 1 (van gogh, Drosophila)	0.746
Sox9	SRY-box containing gene 9	0.693
Phox2b	paired-like homeobox 2b	0.653
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.642
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.626
Otx1	orthodenticle homolog 1 (Drosophila)	0.616
Insm1	insulinoma-associated 1	0.597
Hoxd13	homeobox D13	0.593
En1	engrailed 1	0.587
Tcfap2a	transcription factor AP-2, alpha	0.581
Fgf10	fibroblast growth factor 10	0.581
Pdx1	pancreatic and duodenal homeobox 1	0.574
Foxc1	forkhead box C1	0.567
Foxc2	forkhead box C2	0.566
Hoxb3	homeobox B3	0.553	Mouse
Lhx3	LIM homeobox protein 3	0.542
Hoxa2	homeobox A2	0.522
Tbx1	T-box 1	0.505
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.497
Eya1	eyes absent 1 homolog (Drosophila)	0.492
Lmx1a	LIM homeobox transcription factor 1 alpha	0.476	Mouse
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.476
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.404
Rarg	retinoic acid receptor, gamma	0.396
Nkx6-1	NK6 homeobox 1	0.390
Msx1	homeobox, msh-like 1	0.384
Hes5	hairy and enhancer of split 5 (Drosophila)	0.354
Pitx1	paired-like homeodomain transcription factor 1	0.349
Onecut1	one cut domain, family member 1	0.338
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.321	Worm
Fgfr2	fibroblast growth factor receptor 2	0.318
Foxg1	forkhead box G1	0.287
Nog	noggin	0.267
Hoxa1	homeobox A1	0.262
Sox3	SRY-box containing gene 3	0.261
Wnt1	wingless-related MMTV integration site 1	0.246	Fly
Ptk7	PTK7 protein tyrosine kinase 7	0.226
Col2a1	collagen, type II, alpha 1	0.226
Lmx1b	LIM homeobox transcription factor 1 beta	0.224	Mouse
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.219
Sall3	sal-like 3 (Drosophila)	0.215
Hoxd9	homeobox D9	0.212
Wt1	Wilms tumor 1 homolog	0.205
Hoxb1	homeobox B1	0.205
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.200
Neurog2	neurogenin 2	0.200
Hmx1	H6 homeobox 1	0.197
Sox11	SRY-box containing gene 11	0.194
Nkx3-2	NK3 homeobox 2	0.187
Wnt3a	wingless-related MMTV integration site 3A	0.179
Msx2	homeobox, msh-like 2	0.177
Pax9	paired box gene 9	0.173
Hoxa13	homeobox A13	0.170
Dlx1	distal-less homeobox 1	0.159
Pou4f2	POU domain, class 4, transcription factor 2	0.152
Hand2	heart and neural crest derivatives expressed transcript 2	0.148
Dlx5	distal-less homeobox 5	0.146
Neurod1	neurogenic differentiation 1	0.140
Alx4	aristaless-like homeobox 4	0.139
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.138
Foxb1	forkhead box B1	0.131
Hoxa4	homeobox A4	0.130
Gdnf	glial cell line derived neurotrophic factor	0.127
Hoxd11	homeobox D11	0.125
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.125
Pax1	paired box gene 1	0.123
T	brachyury	0.123
Hoxd1	homeobox D1	0.122
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.122
Col22a1	collagen, type XXII, alpha 1	0.116
Ptf1a	pancreas specific transcription factor, 1a	0.115
Gsc	goosecoid homeobox	0.109
Hoxb2	homeobox B2	0.103
Uncx	UNC homeobox	0.098
Tbx3	T-box 3	0.098
Fgf3	fibroblast growth factor 3	0.093
Atoh7	atonal homolog 7 (Drosophila)	0.091
Hoxa5	homeobox A5	0.086
Pax7	paired box gene 7	0.083
Hoxb4	homeobox B4	0.082
Hoxb6	homeobox B6	0.079
Rarb	retinoic acid receptor, beta	0.075
Efna4	ephrin A4	0.073
Tcfap2c	transcription factor AP-2, gamma	0.073
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.072
Hoxb5	homeobox B5	0.071
Igfbpl1	insulin-like growth factor binding protein-like 1	0.071
Prrx2	paired related homeobox 2	0.069
Hoxa10	homeobox A10	0.068
Ihh	Indian hedgehog	0.068
Hoxa3	homeobox A3	0.067	Mouse
Zic2	zinc finger protein of the cerebellum 2	0.066
Smo	smoothened homolog (Drosophila)	0.065
Tlx3	T-cell leukemia, homeobox 3	0.064
Barx1	BarH-like homeobox 1	0.064	Mouse
Foxf1a	forkhead box F1a	0.063
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.061
Bmp7	bone morphogenetic protein 7	0.061
Lef1	lymphoid enhancer binding factor 1	0.061
Hand1	heart and neural crest derivatives expressed transcript 1	0.060
Dlx2	distal-less homeobox 2	0.060
Pou3f4	POU domain, class 3, transcription factor 4	0.060
Mab21l2	mab-21-like 2 (C. elegans)	0.060
Sap18	Sin3-associated polypeptide 18	0.059
Arx	aristaless related homeobox	0.056
Fgfr3	fibroblast growth factor receptor 3	0.052
Phox2a	paired-like homeobox 2a	0.051
Nhlh1	nescient helix loop helix 1	0.051
Hes1	hairy and enhancer of split 1 (Drosophila)	0.050
Hoxa11	homeobox A11	0.050
Tbx15	T-box 15	0.050
Pitx3	paired-like homeodomain transcription factor 3	0.049
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.049
Msi1	Musashi homolog 1(Drosophila)	0.049
Fgf15	fibroblast growth factor 15	0.048
Sim2	single-minded homolog 2 (Drosophila)	0.047
Hoxa9	homeobox A9	0.047
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.045
Pou3f3	POU domain, class 3, transcription factor 3	0.044
Neurog3	neurogenin 3	0.044
Ebf3	early B-cell factor 3	0.044
Twist2	twist homolog 2 (Drosophila)	0.043
Myog	myogenin	0.042
Msx3	homeobox, msh-like 3	0.042
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.041	Worm
Hmx3	H6 homeobox 3	0.040
Hoxc4	homeobox C4	0.038
Evx1	even skipped homeotic gene 1 homolog	0.038
Trp63	transformation related protein 63	0.038
Vax1	ventral anterior homeobox containing gene 1	0.037
Zic1	zinc finger protein of the cerebellum 1	0.036
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.036
Nkx2-1	NK2 homeobox 1	0.035
BC024139	cDNA sequence BC024139	0.035
Neurog1	neurogenin 1	0.035
Hes3	hairy and enhancer of split 3 (Drosophila)	0.034
Ret	ret proto-oncogene	0.034
Ncoa3	nuclear receptor coactivator 3	0.033
Twist1	twist homolog 1 (Drosophila)	0.032
Myod1	myogenic differentiation 1	0.031
Kiss1	KiSS-1 metastasis-suppressor	0.031
Padi3	peptidyl arginine deiminase, type III	0.030
Tbx2	T-box 2	0.029
Hoxc8	homeobox C8	0.029
Gata3	GATA binding protein 3	0.029
Hoxd10	homeobox D10	0.029
Ephb2	Eph receptor B2	0.029
Atoh1	atonal homolog 1 (Drosophila)	0.028
Sim1	single-minded homolog 1 (Drosophila)	0.028
Shox2	short stature homeobox 2	0.027
Sall4	sal-like 4 (Drosophila)	0.027
Bnc1	basonuclin 1	0.027
En2	engrailed 2	0.027
Zfp503	zinc finger protein 503	0.026
Fgf17	fibroblast growth factor 17	0.026
Sox14	SRY-box containing gene 14	0.026
Tcf15	transcription factor 15	0.026
Wnt11	wingless-related MMTV integration site 11	0.026
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.025
Aplnr	apelin receptor	0.025
Hoxd8	homeobox D8	0.025
Hoxd4	homeobox D4	0.025
Emid2	EMI domain containing 2	0.025
Pax8	paired box gene 8	0.024
Ptgdr	prostaglandin D receptor	0.024
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.024
Fgfr1	fibroblast growth factor receptor 1	0.024
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.024
Pthlh	parathyroid hormone-like peptide	0.023
Hoxb9	homeobox B9	0.023
Col25a1	collagen, type XXV, alpha 1	0.023
Gpr27	G protein-coupled receptor 27	0.023
Hesx1	homeobox gene expressed in ES cells	0.023
Prop1	paired like homeodomain factor 1	0.023
Lhx9	LIM homeobox protein 9	0.023	Mouse
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.022
Wnt6	wingless-related MMTV integration site 6	0.022
Meox2	mesenchyme homeobox 2	0.022
Hoxa7	homeobox A7	0.022
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.022
Hoxb7	homeobox B7	0.022
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.022
Cbx2	chromobox homolog 2 (Drosophila Pc class)	0.021
Foxd3	forkhead box D3	0.021
Sox21	SRY-box containing gene 21	0.021
Gli1	GLI-Kruppel family member GLI1	0.021	Zebrafish Mouse
Smad6	MAD homolog 6 (Drosophila)	0.021
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.021
Pou3f1	POU domain, class 3, transcription factor 1	0.021
Sox10	SRY-box containing gene 10	0.021
Wnt8b	wingless related MMTV integration site 8b	0.021
Hoxc6	homeobox C6	0.020
Gsx2	GS homeobox 2	0.020	Mouse
Stra8	stimulated by retinoic acid gene 8	0.020
Hmx2	H6 homeobox 2	0.020
Bmp4	bone morphogenetic protein 4	0.020
Adra2b	adrenergic receptor, alpha 2b	0.020
Robo3	roundabout homolog 3 (Drosophila)	0.019
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.019
Chrd	chordin	0.019
G6pc2	glucose-6-phosphatase, catalytic, 2	0.019
Foxd2	forkhead box D2	0.019
Setdb1	SET domain, bifurcated 1	0.019
Irx2	Iroquois related homeobox 2 (Drosophila)	0.019
Foxe3	forkhead box E3	0.019
Sp5	trans-acting transcription factor 5	0.018
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.018
Wnt3	wingless-related MMTV integration site 3	0.018
Irx1	Iroquois related homeobox 1 (Drosophila)	0.017
Lhx4	LIM homeobox protein 4	0.017	Mouse
Alx3	aristaless-like homeobox 3	0.017
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.017
Matn3	matrilin 3	0.017
Dmbx1	diencephalon/mesencephalon homeobox 1	0.017
Rara	retinoic acid receptor, alpha	0.017
Tlx1	T-cell leukemia, homeobox 1	0.017
Foxb2	forkhead box B2	0.017
Sp8	trans-acting transcription factor 8	0.017
Col13a1	collagen, type XIII, alpha 1	0.017
Hoxc5	homeobox C5	0.016
Zic4	zinc finger protein of the cerebellum 4	0.016
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.016
Adra2a	adrenergic receptor, alpha 2a	0.016
Mnx1	motor neuron and pancreas homeobox 1	0.016
Foxl2	forkhead box L2	0.016
Tcfap2b	transcription factor AP-2 beta	0.016
Dmrt1	doublesex and mab-3 related transcription factor 1	0.016	Mouse
Gdf5	growth differentiation factor 5	0.015
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.015
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.015
Tlx2	T-cell leukemia, homeobox 2	0.015
Foxa1	forkhead box A1	0.015	Worm
Hmga2	high mobility group AT-hook 2	0.015
Hhex	hematopoietically expressed homeobox	0.015
Foxf2	forkhead box F2	0.015
Hoxd12	homeobox D12	0.015
Rax	retina and anterior neural fold homeobox	0.015
Magel2	melanoma antigen, family L, 2	0.015
Col9a2	collagen, type IX, alpha 2	0.014
Dlx6	distal-less homeobox 6	0.014
Barhl2	BarH-like 2 (Drosophila)	0.014
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.014
Foxh1	forkhead box H1	0.014
Fgf20	fibroblast growth factor 20	0.014
Vsx2	visual system homeobox 2	0.014
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.014
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.014
Fzd10	frizzled homolog 10 (Drosophila)	0.014
Lhx6	LIM homeobox protein 6	0.014	Mouse
Isl2	insulin related protein 2 (islet 2)	0.013	Mouse Fly
Pcdh12	protocadherin 12	0.013
Alx1	ALX homeobox 1	0.013
Vgll2	vestigial like 2 homolog (Drosophila)	0.013
Cdx1	caudal type homeobox 1	0.013
Olig2	oligodendrocyte transcription factor 2	0.013
Foxd1	forkhead box D1	0.013
Chd7	chromodomain helicase DNA binding protein 7	0.013
Gja3	gap junction protein, alpha 3	0.013
Dact3	dapper homolog 3, antagonist of beta-catenin (xenopus)	0.013
Phlda2	pleckstrin homology-like domain, family A, member 2	0.013
Dll1	delta-like 1 (Drosophila)	0.013
Osr1	odd-skipped related 1 (Drosophila)	0.013
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.012
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.012
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.012
Gata4	GATA binding protein 4	0.012
Rassf10	Ras association (RalGDS/AF-6) domain family (N-terminal) member 10	0.012
Pygo1	pygopus 1	0.012
Neurod4	neurogenic differentiation 4	0.012
Hnf4a	hepatic nuclear factor 4, alpha	0.012
Nkd1	naked cuticle 1 homolog (Drosophila)	0.012
Onecut2	one cut domain, family member 2	0.012
Plac1	placental specific protein 1	0.012
Snai1	snail homolog 1 (Drosophila)	0.012
Olig3	oligodendrocyte transcription factor 3	0.012
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.012
Irx5	Iroquois related homeobox 5 (Drosophila)	0.012
2610109H07Rik	RIKEN cDNA 2610109H07 gene	0.012
Lgals3	lectin, galactose binding, soluble 3	0.012
Hoxb13	homeobox B13	0.011
Foxn4	forkhead box N4	0.011
Pou4f3	POU domain, class 4, transcription factor 3	0.011
Sox1	SRY-box containing gene 1	0.011
Mab21l1	mab-21-like 1 (C. elegans)	0.011
Fgf6	fibroblast growth factor 6	0.011
Fgf18	fibroblast growth factor 18	0.011
Mdfi	MyoD family inhibitor	0.011
Zfp219	zinc finger protein 219	0.011
Fgf9	fibroblast growth factor 9	0.011
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.011
Foxn1	forkhead box N1	0.011
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.011	Fly
Pou4f1	POU domain, class 4, transcription factor 1	0.011
Zfhx4	zinc finger homeodomain 4	0.011
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.010
Dmrtb1	DMRT-like family B with proline-rich C-terminal, 1	0.010
Nrtn	neurturin	0.010
Tbx10	T-box 10	0.010
Fbrs	fibrosin	0.010
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.010
Fev	FEV (ETS oncogene family)	0.010
Evx2	even skipped homeotic gene 2 homolog	0.010	Mouse