IMP

Process View

Mus musculus

7 genes annotated in mouse

branchiomotor neuron axon guidance

The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "branchiomotor neuron axon guidance"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "branchiomotor neuron axon guidance" (in gray)

Name	Description	Probability	Func Analog Organism
Plxna1	plexin A1	0.995	Mouse
Arhgef11	Rho guanine nucleotide exchange factor (GEF) 11	0.980
Ednra	endothelin receptor type A	0.898
Vegfa	vascular endothelial growth factor A	0.835
Nrp2	neuropilin 2	0.785
Sdc3	syndecan 3	0.727
Epha4	Eph receptor A4	0.684
Fzd1	frizzled homolog 1 (Drosophila)	0.607
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.549	Mouse
Flt1	FMS-like tyrosine kinase 1	0.512
Rarg	retinoic acid receptor, gamma	0.508
Grb10	growth factor receptor bound protein 10	0.452
Ids	iduronate 2-sulfatase	0.440
Ednrb	endothelin receptor type B	0.428
Fzd2	frizzled homolog 2 (Drosophila)	0.408
Itga3	integrin alpha 3	0.402
Acvr1	activin A receptor, type 1	0.390
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.389
Dlg4	discs, large homolog 4 (Drosophila)	0.387
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.342
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.331
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.316
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.294
Pdgfb	platelet derived growth factor, B polypeptide	0.292
Lama5	laminin, alpha 5	0.219
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.215
Ephb2	Eph receptor B2	0.213
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.212
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.205
Ece1	endothelin converting enzyme 1	0.198
Pbx1	pre B-cell leukemia transcription factor 1	0.180
Tcf4	transcription factor 4	0.170
Mgat3	mannoside acetylglucosaminyltransferase 3	0.159
Mkl2	MKL/myocardin-like 2	0.155
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.133	Mouse
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.132
Fgfr2	fibroblast growth factor receptor 2	0.124
Tspan9	tetraspanin 9	0.122
Mid2	midline 2	0.118
Col12a1	collagen, type XII, alpha 1	0.113
Cdk14	cyclin-dependent kinase 14	0.112
Rara	retinoic acid receptor, alpha	0.110
Smad3	MAD homolog 3 (Drosophila)	0.108
Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.103
Gli3	GLI-Kruppel family member GLI3	0.103
Nrcam	neuron-glia-CAM-related cell adhesion molecule	0.097
Btbd3	BTB (POZ) domain containing 3	0.096
Ddr2	discoidin domain receptor family, member 2	0.095
Emp2	epithelial membrane protein 2	0.090
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.089
Epas1	endothelial PAS domain protein 1	0.087
Plcg1	phospholipase C, gamma 1	0.084
Htt	huntingtin	0.081
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.079	Mouse
Mmp15	matrix metallopeptidase 15	0.078
Etl4	enhancer trap locus 4	0.077
Gpr27	G protein-coupled receptor 27	0.076
Sh3rf1	SH3 domain containing ring finger 1	0.074
Epha3	Eph receptor A3	0.073
Spry4	sprouty homolog 4 (Drosophila)	0.073
Clip2	CAP-GLY domain containing linker protein 2	0.072
Src	Rous sarcoma oncogene	0.070
Nynrin	NYN domain and retroviral integrase containing	0.070
Bcl2	B-cell leukemia/lymphoma 2	0.069
Plcb1	phospholipase C, beta 1	0.068
Mrc2	mannose receptor, C type 2	0.067
Sirpa	signal-regulatory protein alpha	0.066
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.065
Phldb1	pleckstrin homology-like domain, family B, member 1	0.064
Nes	nestin	0.064
Epn2	epsin 2	0.062
Tgfbr3	transforming growth factor, beta receptor III	0.062
Kdr	kinase insert domain protein receptor	0.062
Hip1	huntingtin interacting protein 1	0.061
Wnt5a	wingless-related MMTV integration site 5A	0.059
Fjx1	four jointed box 1 (Drosophila)	0.056
Nf1	neurofibromatosis 1	0.055
Dock4	dedicator of cytokinesis 4	0.054
Bcar1	breast cancer anti-estrogen resistance 1	0.053
Notch3	Notch gene homolog 3 (Drosophila)	0.053
Efnb1	ephrin B1	0.053
Rgnef	Rho-guanine nucleotide exchange factor	0.050
Smad5	MAD homolog 5 (Drosophila)	0.050
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.049
Ptprb	protein tyrosine phosphatase, receptor type, B	0.047
Tubb4	tubulin, beta 4	0.046
Sox4	SRY-box containing gene 4	0.046
Mfap2	microfibrillar-associated protein 2	0.046
Ldb2	LIM domain binding 2	0.045
Efnb2	ephrin B2	0.045
S1pr3	sphingosine-1-phosphate receptor 3	0.045
Pcdh12	protocadherin 12	0.044
Axin2	axin2	0.044
Dtna	dystrobrevin alpha	0.044
Fgfr1	fibroblast growth factor receptor 1	0.043
Tgfb2	transforming growth factor, beta 2	0.042
Dpysl2	dihydropyrimidinase-like 2	0.042
Zeb2	zinc finger E-box binding homeobox 2	0.042
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.042
Vipr2	vasoactive intestinal peptide receptor 2	0.040
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.039
Nfia	nuclear factor I/A	0.035
Ptprg	protein tyrosine phosphatase, receptor type, G	0.035
Ptgfrn	prostaglandin F2 receptor negative regulator	0.034
Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	0.034
She	src homology 2 domain-containing transforming protein E	0.034
Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.034
Pcdh18	protocadherin 18	0.034
Cdh13	cadherin 13	0.033
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.033
Aplnr	apelin receptor	0.032
Tnks1bp1	tankyrase 1 binding protein 1	0.032
Unc5c	unc-5 homolog C (C. elegans)	0.032
Hap1	huntingtin-associated protein 1	0.032
Myo10	myosin X	0.031
Mark4	MAP/microtubule affinity-regulating kinase 4	0.031
Ret	ret proto-oncogene	0.031
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.031
Gata6	GATA binding protein 6	0.030
Kitl	kit ligand	0.030
Gnao1	guanine nucleotide binding protein, alpha O	0.030
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.029
Neo1	neogenin	0.029
Cbl	Casitas B-lineage lymphoma	0.029
Rarb	retinoic acid receptor, beta	0.029
Fzd7	frizzled homolog 7 (Drosophila)	0.028
Ptpru	protein tyrosine phosphatase, receptor type, U	0.028
Lrp1	low density lipoprotein receptor-related protein 1	0.028
Jup	junction plakoglobin	0.027
Arhgef17	Rho guanine nucleotide exchange factor (GEF) 17	0.027
Lamc1	laminin, gamma 1	0.026
Fign	fidgetin	0.026
Pecam1	platelet/endothelial cell adhesion molecule 1	0.026
Utrn	utrophin	0.026
Tbx3	T-box 3	0.026
Gab2	growth factor receptor bound protein 2-associated protein 2	0.026
Zfpm2	zinc finger protein, multitype 2	0.025
Nav1	neuron navigator 1	0.025
Ptprk	protein tyrosine phosphatase, receptor type, K	0.025
Ephb3	Eph receptor B3	0.025
Tbx2	T-box 2	0.025
Cpd	carboxypeptidase D	0.025
Rgs5	regulator of G-protein signaling 5	0.025
Slit2	slit homolog 2 (Drosophila)	0.025
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.024
Ptk2	PTK2 protein tyrosine kinase 2	0.024
Gpc3	glypican 3	0.024
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.023
Wnt7b	wingless-related MMTV integration site 7B	0.023
Klf7	Kruppel-like factor 7 (ubiquitous)	0.023
Fgf18	fibroblast growth factor 18	0.023
Sox7	SRY-box containing gene 7	0.022
Timp2	tissue inhibitor of metalloproteinase 2	0.022
Bcl6b	B-cell CLL/lymphoma 6, member B	0.022
Cdh6	cadherin 6	0.022
Bmp5	bone morphogenetic protein 5	0.021
Sorbs3	sorbin and SH3 domain containing 3	0.021
Arl10	ADP-ribosylation factor-like 10	0.021
Edn1	endothelin 1	0.021
Epb4.1l2	erythrocyte protein band 4.1-like 2	0.021
Hdac7	histone deacetylase 7	0.021
Ptprs	protein tyrosine phosphatase, receptor type, S	0.020
Ebf3	early B-cell factor 3	0.020
Kif1a	kinesin family member 1A	0.019
Apc2	adenomatosis polyposis coli 2	0.019
Cxadr	coxsackie virus and adenovirus receptor	0.019
Cachd1	cache domain containing 1	0.019
Ptprm	protein tyrosine phosphatase, receptor type, M	0.019
Fzd6	frizzled homolog 6 (Drosophila)	0.019
Npnt	nephronectin	0.019
Nos3	nitric oxide synthase 3, endothelial cell	0.019
Ephb4	Eph receptor B4	0.019
Mtap1b	microtubule-associated protein 1B	0.019
Ncoa2	nuclear receptor coactivator 2	0.018
Ptk7	PTK7 protein tyrosine kinase 7	0.018
Tead3	TEA domain family member 3	0.018
Birc6	baculoviral IAP repeat-containing 6	0.018
Zfp358	zinc finger protein 358	0.018
Apc	adenomatosis polyposis coli	0.017
Rgs4	regulator of G-protein signaling 4	0.017
Ltbp1	latent transforming growth factor beta binding protein 1	0.017
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.017
Cdc42bpa	CDC42 binding protein kinase alpha	0.016
Wwc2	WW, C2 and coiled-coil domain containing 2	0.016
Fyn	Fyn proto-oncogene	0.016
Matn4	matrilin 4	0.016
Nsd1	nuclear receptor-binding SET-domain protein 1	0.016
Id1	inhibitor of DNA binding 1	0.016
Plxnb1	plexin B1	0.015	Mouse
Rac3	RAS-related C3 botulinum substrate 3	0.015
Dpysl3	dihydropyrimidinase-like 3	0.015
Prox1	prospero-related homeobox 1	0.015
Col4a5	collagen, type IV, alpha 5	0.015
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.015
Cacng7	calcium channel, voltage-dependent, gamma subunit 7	0.015
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.015
Efna2	ephrin A2	0.015
Efna5	ephrin A5	0.015
Ptrf	polymerase I and transcript release factor	0.015
Zfp518b	zinc finger protein 518B	0.015
Angpt1	angiopoietin 1	0.015
Prrx1	paired related homeobox 1	0.014
Epha2	Eph receptor A2	0.014
Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.014
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.014
Fam115a	family with sequence similarity 115, member A	0.014
Fat4	FAT tumor suppressor homolog 4 (Drosophila)	0.014
Wwtr1	WW domain containing transcription regulator 1	0.014
Nrp1	neuropilin 1	0.014
Polm	polymerase (DNA directed), mu	0.014
Meis2	Meis homeobox 2	0.013
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.013
Acvrl1	activin A receptor, type II-like 1	0.013
Zswim6	zinc finger, SWIM domain containing 6	0.013
Rxra	retinoid X receptor alpha	0.013
Magi3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.013
Igf1r	insulin-like growth factor I receptor	0.013
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.013
Bcam	basal cell adhesion molecule	0.013
D530037H12Rik	RIKEN cDNA D530037H12 gene	0.013
Fli1	Friend leukemia integration 1	0.013
Gpc6	glypican 6	0.013
Foxp2	forkhead box P2	0.013
Cdh4	cadherin 4	0.013
Fmnl3	formin-like 3	0.012
Ccdc24	coiled-coil domain containing 24	0.012
Msi1	Musashi homolog 1(Drosophila)	0.012
Gata4	GATA binding protein 4	0.012
Prkci	protein kinase C, iota	0.012
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.012
Dll1	delta-like 1 (Drosophila)	0.012
Srgap1	SLIT-ROBO Rho GTPase activating protein 1	0.012
Pcdhb21	protocadherin beta 21	0.012
Kalrn	kalirin, RhoGEF kinase	0.012
Pcdh1	protocadherin 1	0.012
Cdh11	cadherin 11	0.012
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.012
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.012
Dchs1	dachsous 1 (Drosophila)	0.012
Sntb1	syntrophin, basic 1	0.012
Clstn2	calsyntenin 2	0.012
Plxnd1	plexin D1	0.012	Mouse
Zfp871	zinc finger protein 871	0.011
Auts2	autism susceptibility candidate 2	0.011
Fzd8	frizzled homolog 8 (Drosophila)	0.011
Capn5	calpain 5	0.011
Macf1	microtubule-actin crosslinking factor 1	0.011
Akt3	thymoma viral proto-oncogene 3	0.011
Zfp185	zinc finger protein 185	0.011
Mpdz	multiple PDZ domain protein	0.011
Hgf	hepatocyte growth factor	0.011
Jag1	jagged 1	0.011
Ccdc88a	coiled coil domain containing 88A	0.011
Ppl	periplakin	0.011
Bmp4	bone morphogenetic protein 4	0.011
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.011
Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.011
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.011
Sox11	SRY-box containing gene 11	0.011
Mef2c	myocyte enhancer factor 2C	0.011
Gpr56	G protein-coupled receptor 56	0.011
Ptprf	protein tyrosine phosphatase, receptor type, F	0.011
Pdgfa	platelet derived growth factor, alpha	0.011
Sbf2	SET binding factor 2	0.011
Dll4	delta-like 4 (Drosophila)	0.011
Podxl	podocalyxin-like	0.011
Cd93	CD93 antigen	0.011
Kit	kit oncogene	0.010
Rasip1	Ras interacting protein 1	0.010
Fn1	fibronectin 1	0.010
Spnb2	spectrin beta 2	0.010
Ptpre	protein tyrosine phosphatase, receptor type, E	0.010
Rdh10	retinol dehydrogenase 10 (all-trans)	0.010
Gdf11	growth differentiation factor 11	0.010
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.010
Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	0.010
Lama4	laminin, alpha 4	0.010
Amotl2	angiomotin-like 2	0.010
Palm2	paralemmin 2	0.010
Jag2	jagged 2	0.010