IMP

Process View

Mus musculus

13 genes annotated in mouse

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positive regulation of coagulation

GO:0050820

Any process that activates or increases the frequency, rate or extent of coagulation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of coagulation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of coagulation" (in gray)

Name	Description	Probability	Func Analog Organism
Ccr2	chemokine (C-C motif) receptor 2	0.867
Selp	selectin, platelet	0.600
Cd44	CD44 antigen	0.364
Tlr4	toll-like receptor 4	0.319
Ccl2	chemokine (C-C motif) ligand 2	0.307
Apoa1	apolipoprotein A-I	0.272
Cav1	caveolin 1, caveolae protein	0.258
Tlr2	toll-like receptor 2	0.232	Mouse
Notch1	Notch gene homolog 1 (Drosophila)	0.199
Mmp9	matrix metallopeptidase 9	0.132
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.120
Notch2	Notch gene homolog 2 (Drosophila)	0.098
Sell	selectin, lymphocyte	0.095	Mouse
Cdh5	cadherin 5	0.089
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.084
C5ar1	complement component 5a receptor 1	0.078
Cxcl2	chemokine (C-X-C motif) ligand 2	0.074
Vhl	von Hippel-Lindau tumor suppressor	0.072
Sele	selectin, endothelial cell	0.071	Mouse
Itgb3	integrin beta 3	0.069
Spp1	secreted phosphoprotein 1	0.065
Plaur	plasminogen activator, urokinase receptor	0.062
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.055
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.050
Plg	plasminogen	0.048	Human
Lair1	leukocyte-associated Ig-like receptor 1	0.047
Ncstn	nicastrin	0.044
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.043
Ush1c	Usher syndrome 1C homolog (human)	0.043
Pah	phenylalanine hydroxylase	0.041
Plau	plasminogen activator, urokinase	0.040
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.040
Fga	fibrinogen alpha chain	0.039
Slc12a6	solute carrier family 12, member 6	0.036
Ccr5	chemokine (C-C motif) receptor 5	0.036
Gc	group specific component	0.036
Smad1	MAD homolog 1 (Drosophila)	0.035
Osmr	oncostatin M receptor	0.034
Mt1	metallothionein 1	0.034
Il10	interleukin 10	0.033
Il1rn	interleukin 1 receptor antagonist	0.032
Foxo1	forkhead box O1	0.032
F2	coagulation factor II	0.031	Human
Kng1	kininogen 1	0.030
Cxcr2	chemokine (C-X-C motif) receptor 2	0.029
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.028
Cfi	complement component factor i	0.028
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.028
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.028
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.028
Alb	albumin	0.026
Ambp	alpha 1 microglobulin/bikunin	0.026
Prdx4	peroxiredoxin 4	0.025	Mouse
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.024
Sdhd	succinate dehydrogenase complex, subunit D, integral membrane protein	0.024
Cyr61	cysteine rich protein 61	0.024
Cd33	CD33 antigen	0.023
Myd88	myeloid differentiation primary response gene 88	0.023
Apob	apolipoprotein B	0.023
Hif1a	hypoxia inducible factor 1, alpha subunit	0.022
Hamp	hepcidin antimicrobial peptide	0.022
Ifngr1	interferon gamma receptor 1	0.022
Was	Wiskott-Aldrich syndrome homolog (human)	0.022
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.022
F10	coagulation factor X	0.021
Dap	death-associated protein	0.021
Mcl1	myeloid cell leukemia sequence 1	0.021
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.021
Fabp4	fatty acid binding protein 4, adipocyte	0.021
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.021
Tmem14c	transmembrane protein 14C	0.021
App	amyloid beta (A4) precursor protein	0.020
Lcp2	lymphocyte cytosolic protein 2	0.020
Apoc4	apolipoprotein C-IV	0.020
Mat1a	methionine adenosyltransferase I, alpha	0.020
Fgg	fibrinogen gamma chain	0.020
Hgfac	hepatocyte growth factor activator	0.020
Proc	protein C	0.020
Cnpy2	canopy 2 homolog (zebrafish)	0.020
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.019
Slfn4	schlafen 4	0.019
Gp5	glycoprotein 5 (platelet)	0.019
Tmed10	transmembrane emp24-like trafficking protein 10 (yeast)	0.019
Rdh7	retinol dehydrogenase 7	0.019
Grxcr1	glutaredoxin, cysteine rich 1	0.019
Casp1	caspase 1	0.019
Slfn1	schlafen 1	0.018
Mmp8	matrix metallopeptidase 8	0.018
Sykb	spleen tyrosine kinase	0.018
Hgd	homogentisate 1, 2-dioxygenase	0.018
Lipc	lipase, hepatic	0.017
Gp9	glycoprotein 9 (platelet)	0.017
Sar1b	SAR1 gene homolog B (S. cerevisiae)	0.017
Creg1	cellular repressor of E1A-stimulated genes 1	0.017
Hpx	hemopexin	0.017
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.017
Pzp	pregnancy zone protein	0.016
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.016
Fcgr1	Fc receptor, IgG, high affinity I	0.016
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.016
Tnc	tenascin C	0.016
Gpr97	G protein-coupled receptor 97	0.016
Ptgs2	prostaglandin-endoperoxide synthase 2	0.016
Fpr2	formyl peptide receptor 2	0.015
Icam1	intercellular adhesion molecule 1	0.015
Ndufb6	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6	0.015
Ccr1	chemokine (C-C motif) receptor 1	0.015
Aph1a	anterior pharynx defective 1a homolog (C. elegans)	0.015
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.015
Ush1g	Usher syndrome 1G homolog (human)	0.015
Cyb5	cytochrome b-5	0.015
Syn1	synapsin I	0.015
Asgr2	asialoglycoprotein receptor 2	0.014
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.014
Hbb-b1	hemoglobin, beta adult major chain	0.014
Gjb2	gap junction protein, beta 2	0.014
Cideb	cell death-inducing DNA fragmentation factor, alpha subunit-like effector B	0.014
Il6	interleukin 6	0.014
Soat2	sterol O-acyltransferase 2	0.014
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.014
Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	0.013
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.013
Tpp1	tripeptidyl peptidase I	0.013
Ppbp	pro-platelet basic protein	0.013
Ncr1	natural cytotoxicity triggering receptor 1	0.013
Afm	afamin	0.013
Gdf2	growth differentiation factor 2	0.013
Txn1	thioredoxin 1	0.013
Ticam1	toll-like receptor adaptor molecule 1	0.013
Pyhin1	pyrin and HIN domain family, member 1	0.013
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.012
Clec4d	C-type lectin domain family 4, member d	0.012
Ctsl	cathepsin L	0.012
Ccl7	chemokine (C-C motif) ligand 7	0.012
C9	complement component 9	0.012
Vcam1	vascular cell adhesion molecule 1	0.012
Gpr35	G protein-coupled receptor 35	0.012
Psma5	proteasome (prosome, macropain) subunit, alpha type 5	0.012
Gsk3b	glycogen synthase kinase 3 beta	0.012
Kdelr1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	0.012
Vnn3	vanin 3	0.012
Slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.012
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.012
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.012
Nod2	nucleotide-binding oligomerization domain containing 2	0.012
Fam96a	family with sequence similarity 96, member A	0.012
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.012
Saa4	serum amyloid A 4	0.012
Il1r1	interleukin 1 receptor, type I	0.011
Apof	apolipoprotein F	0.011
Rgs18	regulator of G-protein signaling 18	0.011
Msr1	macrophage scavenger receptor 1	0.011
Apoa4	apolipoprotein A-IV	0.011
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.011
Gm6484	predicted gene 6484	0.011
Whrn	whirlin	0.011
Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	0.011
Uox	urate oxidase	0.011
Cxcl1	chemokine (C-X-C motif) ligand 1	0.011
Apcs	serum amyloid P-component	0.011
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.011	Human Rat
Rel	reticuloendotheliosis oncogene	0.011
Arhgap30	Rho GTPase activating protein 30	0.011
Cdh1	cadherin 1	0.011
Hnf4a	hepatic nuclear factor 4, alpha	0.011
Smad3	MAD homolog 3 (Drosophila)	0.011
Fgb	fibrinogen beta chain	0.011
Tlr1	toll-like receptor 1	0.011	Mouse
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.010
Il1a	interleukin 1 alpha	0.010
Cd14	CD14 antigen	0.010
Apoa2	apolipoprotein A-II	0.010
Agxt	alanine-glyoxylate aminotransferase	0.010
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.010
Tspan4	tetraspanin 4	0.010
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.010
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.010
Aspdh	aspartate dehydrogenase domain containing	0.010
Cyp26c1	cytochrome P450, family 26, subfamily c, polypeptide 1	0.010
Fli1	Friend leukemia integration 1	0.010
Il22	interleukin 22	0.010