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Mus musculus

17 genes annotated in mouse

ventricular cardiac muscle cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ventricular cardiac muscle cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ventricular cardiac muscle cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Hand2	heart and neural crest derivatives expressed transcript 2	1.000
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	1.000
Hand1	heart and neural crest derivatives expressed transcript 1	0.999
Fgf8	fibroblast growth factor 8	0.998	Zebrafish
Shh	sonic hedgehog	0.998
Gata4	GATA binding protein 4	0.995
Bmp7	bone morphogenetic protein 7	0.993	Mouse
Tbx1	T-box 1	0.992
Rarg	retinoic acid receptor, gamma	0.990	Mouse
Bmp4	bone morphogenetic protein 4	0.984
Foxc1	forkhead box C1	0.983
Sox9	SRY-box containing gene 9	0.982
Tgfb2	transforming growth factor, beta 2	0.980
Fgfr2	fibroblast growth factor receptor 2	0.980
Pitx2	paired-like homeodomain transcription factor 2	0.963
Isl1	ISL1 transcription factor, LIM/homeodomain	0.959
Foxc2	forkhead box C2	0.957
Rxra	retinoid X receptor alpha	0.951
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.949
Chrd	chordin	0.943
Ednra	endothelin receptor type A	0.924
Fgfr3	fibroblast growth factor receptor 3	0.900
Tcfap2a	transcription factor AP-2, alpha	0.896
Prrx1	paired related homeobox 1	0.877
Msx1	homeobox, msh-like 1	0.806
Fgfr1	fibroblast growth factor receptor 1	0.782
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.760
Ece1	endothelin converting enzyme 1	0.716
Acvr1	activin A receptor, type 1	0.702
Smo	smoothened homolog (Drosophila)	0.683
Hoxa1	homeobox A1	0.657
Vegfa	vascular endothelial growth factor A	0.638
Ntf3	neurotrophin 3	0.633
Pax2	paired box gene 2	0.572
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.560	Mouse
Mesp1	mesoderm posterior 1	0.528
Gata6	GATA binding protein 6	0.513
Eya1	eyes absent 1 homolog (Drosophila)	0.499
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.473
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.465
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.424
Gata5	GATA binding protein 5	0.419
Rarb	retinoic acid receptor, beta	0.413
Tbx3	T-box 3	0.361
Gli3	GLI-Kruppel family member GLI3	0.342
Jag1	jagged 1	0.301
Zfpm2	zinc finger protein, multitype 2	0.300
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.279
Tbx5	T-box 5	0.252
Gsc	goosecoid homeobox	0.248
Pax8	paired box gene 8	0.236
Gli2	GLI-Kruppel family member GLI2	0.234
Otx2	orthodenticle homolog 2 (Drosophila)	0.211
Runx2	runt related transcription factor 2	0.205
Dlx5	distal-less homeobox 5	0.201
Birc5	baculoviral IAP repeat-containing 5	0.190
Alx4	aristaless-like homeobox 4	0.187
Pax3	paired box gene 3	0.181
Nrp1	neuropilin 1	0.180
Msx2	homeobox, msh-like 2	0.180
Hdac4	histone deacetylase 4	0.180
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.162
Thrb	thyroid hormone receptor beta	0.140	Mouse
Ltbp1	latent transforming growth factor beta binding protein 1	0.137
Tgfbr2	transforming growth factor, beta receptor II	0.136
Thra	thyroid hormone receptor alpha	0.136	Mouse
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.130
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.125
Nkx6-1	NK6 homeobox 1	0.122
Hdac5	histone deacetylase 5	0.121
Gja1	gap junction protein, alpha 1	0.118
Efnb2	ephrin B2	0.108
Pdx1	pancreatic and duodenal homeobox 1	0.107
Foxh1	forkhead box H1	0.106
Fgfrl1	fibroblast growth factor receptor-like 1	0.105
Pbx1	pre B-cell leukemia transcription factor 1	0.096
Hoxd13	homeobox D13	0.096
Fgf15	fibroblast growth factor 15	0.095
Dbp	D site albumin promoter binding protein	0.094
Foxe1	forkhead box E1	0.094
Chd7	chromodomain helicase DNA binding protein 7	0.093
Pthlh	parathyroid hormone-like peptide	0.092
Tcf21	transcription factor 21	0.090
Gdf6	growth differentiation factor 6	0.089	Mouse
Mef2d	myocyte enhancer factor 2D	0.088	Mouse
Gja5	gap junction protein, alpha 5	0.088
Rara	retinoic acid receptor, alpha	0.085
Prrx2	paired related homeobox 2	0.081
Nog	noggin	0.080
Myl3	myosin, light polypeptide 3	0.079	Zebrafish
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.078	Mouse
Alx3	aristaless-like homeobox 3	0.078
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.077	Mouse
Ccna2	cyclin A2	0.075
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.074
Chrm2	cholinergic receptor, muscarinic 2, cardiac	0.073
Cdk1	cyclin-dependent kinase 1	0.071	Rat
Prc1	protein regulator of cytokinesis 1	0.070
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.068
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.068
Gja3	gap junction protein, alpha 3	0.065
Foxa2	forkhead box A2	0.065
Smad6	MAD homolog 6 (Drosophila)	0.064
Dlx2	distal-less homeobox 2	0.064
Gdf5	growth differentiation factor 5	0.063	Mouse
Barx1	BarH-like homeobox 1	0.063
Ccnb1	cyclin B1	0.062	Rat
En1	engrailed 1	0.062
Dlx6	distal-less homeobox 6	0.061
Plxnd1	plexin D1	0.059
Gas1	growth arrest specific 1	0.058
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.057
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.056
Mef2c	myocyte enhancer factor 2C	0.055
Tbx2	T-box 2	0.053
Bmp2	bone morphogenetic protein 2	0.052	Zebrafish
Emx2	empty spiracles homolog 2 (Drosophila)	0.050
Lmnb1	lamin B1	0.049	Mouse
Zeb1	zinc finger E-box binding homeobox 1	0.049
Vax1	ventral anterior homeobox containing gene 1	0.048
Foxi3	forkhead box I3	0.048
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.047
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.047	Mouse
Ncor2	nuclear receptor co-repressor 2	0.045
Prox1	prospero-related homeobox 1	0.045
Pitx1	paired-like homeodomain transcription factor 1	0.044	Mouse
Cnn1	calponin 1	0.043
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.043
Hoxa13	homeobox A13	0.042
Atg12	autophagy-related 12 (yeast)	0.042
Rdh10	retinol dehydrogenase 10 (all-trans)	0.042
Emx1	empty spiracles homolog 1 (Drosophila)	0.041
Sall4	sal-like 4 (Drosophila)	0.041
Nf1	neurofibromatosis 1	0.039
Ptk2	PTK2 protein tyrosine kinase 2	0.039
Crhr2	corticotropin releasing hormone receptor 2	0.039
Aqp7	aquaporin 7	0.038
Lmnb2	lamin B2	0.038	Mouse
Phox2b	paired-like homeobox 2b	0.038
Sox4	SRY-box containing gene 4	0.038
Nos3	nitric oxide synthase 3, endothelial cell	0.038
Omp	olfactory marker protein	0.038
Kif20a	kinesin family member 20A	0.037
Ighmbp2	immunoglobulin mu binding protein 2	0.037
Fgf9	fibroblast growth factor 9	0.036
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.035
Tbx15	T-box 15	0.034
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.034
Lhx3	LIM homeobox protein 3	0.033
Idua	iduronidase, alpha-L-	0.033
Lmx1b	LIM homeobox transcription factor 1 beta	0.032
Trp63	transformation related protein 63	0.031
Sox3	SRY-box containing gene 3	0.031
Col13a1	collagen, type XIII, alpha 1	0.031
Otp	orthopedia homolog (Drosophila)	0.031
Meox2	mesenchyme homeobox 2	0.030
Wnt5a	wingless-related MMTV integration site 5A	0.030
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.030
Pax9	paired box gene 9	0.029
Actn1	actinin, alpha 1	0.029
Ghr	growth hormone receptor	0.028
ND6	NADH dehydrogenase subunit 6	0.028
Bmper	BMP-binding endothelial regulator	0.028
Edn3	endothelin 3	0.028
Fgf10	fibroblast growth factor 10	0.027
Nppa	natriuretic peptide type A	0.027
Alx1	ALX homeobox 1	0.027
Hrc	histidine rich calcium binding protein	0.026
Lhx1	LIM homeobox protein 1	0.026
Egfr	epidermal growth factor receptor	0.026
Hes5	hairy and enhancer of split 5 (Drosophila)	0.026
Ccnb2	cyclin B2	0.026
Sox7	SRY-box containing gene 7	0.025
Padi1	peptidyl arginine deiminase, type I	0.025
Arx	aristaless related homeobox	0.025
Bmp10	bone morphogenetic protein 10	0.024
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.024
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.024
Gucy1a3	guanylate cyclase 1, soluble, alpha 3	0.024
Btbd17	BTB (POZ) domain containing 17	0.024
Npr3	natriuretic peptide receptor 3	0.024
Akr7a5	aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase)	0.023
Des	desmin	0.023
Kcnk3	potassium channel, subfamily K, member 3	0.022
Mecom	MDS1 and EVI1 complex locus	0.022
Bmp5	bone morphogenetic protein 5	0.021	Mouse
Pax6	paired box gene 6	0.021
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.021
Wnt9b	wingless-type MMTV integration site 9B	0.020
Fut2	fucosyltransferase 2	0.020
Foxg1	forkhead box G1	0.020
Nkx3-2	NK3 homeobox 2	0.019	Mouse
Itga8	integrin alpha 8	0.019
Insm1	insulinoma-associated 1	0.019
Cks2	CDC28 protein kinase regulatory subunit 2	0.019
Prop1	paired like homeodomain factor 1	0.019
Rem1	rad and gem related GTP binding protein 1	0.019
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.018
Pth1r	parathyroid hormone 1 receptor	0.018
Mn1	meningioma 1	0.018
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.018
Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.017
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.017
Lmna	lamin A	0.017
Art5	ADP-ribosyltransferase 5	0.017
Hoxd11	homeobox D11	0.017
Bmp8b	bone morphogenetic protein 8b	0.017	Mouse
Ldb3	LIM domain binding 3	0.017
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.017
Foxf2	forkhead box F2	0.017
Plec	plectin	0.017
Actn2	actinin alpha 2	0.017
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.016
Nfia	nuclear factor I/A	0.016
Kcna7	potassium voltage-gated channel, shaker-related subfamily, member 7	0.016
Foxf1a	forkhead box F1a	0.016
Duox2	dual oxidase 2	0.016
Guca2b	guanylate cyclase activator 2b (retina)	0.016
Tbx20	T-box 20	0.016
Hdac7	histone deacetylase 7	0.016
Scn5a	sodium channel, voltage-gated, type V, alpha	0.016
Sox11	SRY-box containing gene 11	0.016
Dmd	dystrophin, muscular dystrophy	0.016
Mmp15	matrix metallopeptidase 15	0.016
Wnt11	wingless-related MMTV integration site 11	0.016
Tcf15	transcription factor 15	0.015
Adra2b	adrenergic receptor, alpha 2b	0.015
Ebf2	early B-cell factor 2	0.015
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.015
Racgap1	Rac GTPase-activating protein 1	0.015
Spdef	SAM pointed domain containing ets transcription factor	0.015
Myh11	myosin, heavy polypeptide 11, smooth muscle	0.015	Mouse
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.015
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.014
Wnt6	wingless-related MMTV integration site 6	0.014
Drd2	dopamine receptor D2	0.014
Hnf4a	hepatic nuclear factor 4, alpha	0.014	Mouse
Fgf4	fibroblast growth factor 4	0.014
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.014
Actc1	actin, alpha, cardiac muscle 1	0.014
Kif11	kinesin family member 11	0.014
Adrb1	adrenergic receptor, beta 1	0.014
Cxcl12	chemokine (C-X-C motif) ligand 12	0.014
Irs1	insulin receptor substrate 1	0.014
Spry2	sprouty homolog 2 (Drosophila)	0.013
Nfib	nuclear factor I/B	0.013
BC057022	cDNA sequence BC057022	0.013
Prdm16	PR domain containing 16	0.013
Fitm1	fat storage-inducing transmembrane protein 1	0.013
Barx2	BarH-like homeobox 2	0.013
Kcnk2	potassium channel, subfamily K, member 2	0.013
Kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.013
Tshr	thyroid stimulating hormone receptor	0.013
Cxadr	coxsackie virus and adenovirus receptor	0.013
Fgf18	fibroblast growth factor 18	0.013
Sox13	SRY-box containing gene 13	0.013
Lama2	laminin, alpha 2	0.013
Ihh	Indian hedgehog	0.013
Ager	advanced glycosylation end product-specific receptor	0.013
Hmx3	H6 homeobox 3	0.013
Hmx1	H6 homeobox 1	0.013
Hes2	hairy and enhancer of split 2 (Drosophila)	0.013
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.013
Apob	apolipoprotein B	0.012
Hoxa2	homeobox A2	0.012
Clcnka	chloride channel Ka	0.012
Scn10a	sodium channel, voltage-gated, type X, alpha	0.012
Sct	secretin	0.012
Hes1	hairy and enhancer of split 1 (Drosophila)	0.012
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.012
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.012
Jag2	jagged 2	0.012
Smyd1	SET and MYND domain containing 1	0.012
Zeb2	zinc finger E-box binding homeobox 2	0.012
Gbx2	gastrulation brain homeobox 2	0.012
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.012
Bik	BCL2-interacting killer	0.012
Sox2	SRY-box containing gene 2	0.012
Hoxa3	homeobox A3	0.012
Pnliprp2	pancreatic lipase-related protein 2	0.012
Tbx4	T-box 4	0.012
Pkdcc	protein kinase domain containing, cytoplasmic	0.012
Gli1	GLI-Kruppel family member GLI1	0.012
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.011
Tcap	titin-cap	0.011
Pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.011
Sfrp5	secreted frizzled-related sequence protein 5	0.011
Cdx1	caudal type homeobox 1	0.011
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.011
Bcar1	breast cancer anti-estrogen resistance 1	0.011
Cdx2	caudal type homeobox 2	0.011
Aurkb	aurora kinase B	0.011
Gip	gastric inhibitory polypeptide	0.011
Moxd2	monooxygenase, DBH-like 2	0.011
Plk1	polo-like kinase 1 (Drosophila)	0.011
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.011
Sycn	syncollin	0.011
Snai3	snail homolog 3 (Drosophila)	0.011
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.011	Mouse
Hoxa5	homeobox A5	0.011
Pex6	peroxisomal biogenesis factor 6	0.011
Ncoa1	nuclear receptor coactivator 1	0.011
Myl9	myosin, light polypeptide 9, regulatory	0.011
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.011
Krt15	keratin 15	0.011
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.011
Col4a3	collagen, type IV, alpha 3	0.011
Mrvi1	MRV integration site 1	0.011
Ptprb	protein tyrosine phosphatase, receptor type, B	0.010
Npn2	neoplastic progression 2	0.010
Psma4	proteasome (prosome, macropain) subunit, alpha type 4	0.010
Tnxb	tenascin XB	0.010
Adra1a	adrenergic receptor, alpha 1a	0.010
Foxa1	forkhead box A1	0.010
Avp	arginine vasopressin	0.010
Ppard	peroxisome proliferator activator receptor delta	0.010
Glis3	GLIS family zinc finger 3	0.010
Art1	ADP-ribosyltransferase 1	0.010
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.010
Amelx	amelogenin X chromosome	0.010