IMP

Process View

Mus musculus

20 genes annotated in mouse

Multi-species View

cgmp metabolic process

GO:0046068

The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cgmp metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cgmp metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Nos3	nitric oxide synthase 3, endothelial cell	0.862
Atxn1	ataxin 1	0.354
Gnrh1	gonadotropin releasing hormone 1	0.292
Notch2	Notch gene homolog 2 (Drosophila)	0.258
Dlg4	discs, large homolog 4 (Drosophila)	0.256
Ptgs2	prostaglandin-endoperoxide synthase 2	0.256
Mb	myoglobin	0.214
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.208
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.200
Kl	klotho	0.199
Espn	espin	0.177
Lepr	leptin receptor	0.164
Ush1g	Usher syndrome 1G homolog (human)	0.152
Amhr2	anti-Mullerian hormone type 2 receptor	0.138
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.113	Mouse Rat
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.103
Vhl	von Hippel-Lindau tumor suppressor	0.100
Gucy1a3	guanylate cyclase 1, soluble, alpha 3	0.088
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.086
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.084
Nos1	nitric oxide synthase 1, neuronal	0.083
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.081
Kit	kit oncogene	0.080
Tcfcp2l1	transcription factor CP2-like 1	0.080
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.076
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.075
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.074
Myo6	myosin VI	0.073
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.072
Prkg1	protein kinase, cGMP-dependent, type I	0.071
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.067
Slc26a4	solute carrier family 26, member 4	0.067
Crx	cone-rod homeobox containing gene	0.067
Fgfr3	fibroblast growth factor receptor 3	0.064
Grid2	glutamate receptor, ionotropic, delta 2	0.063
Nrp1	neuropilin 1	0.062
Vdr	vitamin D receptor	0.062
Rgs4	regulator of G-protein signaling 4	0.060
Prph2	peripherin 2	0.059
Rax	retina and anterior neural fold homeobox	0.059
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.058
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.056
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.055
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.055
Lyz2	lysozyme 2	0.054
Atoh7	atonal homolog 7 (Drosophila)	0.054
Grxcr1	glutaredoxin, cysteine rich 1	0.054
Esr1	estrogen receptor 1 (alpha)	0.052
Bcar1	breast cancer anti-estrogen resistance 1	0.051
Fzd4	frizzled homolog 4 (Drosophila)	0.047
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.046
Tspan12	tetraspanin 12	0.046
Itga3	integrin alpha 3	0.045
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.044
Gdnf	glial cell line derived neurotrophic factor	0.044
Kiss1	KiSS-1 metastasis-suppressor	0.043
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.042
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.041
Rs1	retinoschisis (X-linked, juvenile) 1 (human)	0.041
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.040
Rho	rhodopsin	0.039
Slc12a3	solute carrier family 12, member 3	0.038
Aqp2	aquaporin 2	0.038
Pcdh15	protocadherin 15	0.037
Gpr98	G protein-coupled receptor 98	0.036
Pgr	progesterone receptor	0.036
Fbn1	fibrillin 1	0.035
Agtr1a	angiotensin II receptor, type 1a	0.035
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.035
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.034
Ptpn5	protein tyrosine phosphatase, non-receptor type 5	0.033
Pdgfb	platelet derived growth factor, B polypeptide	0.033
Fyn	Fyn proto-oncogene	0.033
Vegfa	vascular endothelial growth factor A	0.031	Human
Hnf4a	hepatic nuclear factor 4, alpha	0.030
Egr1	early growth response 1	0.030
Shh	sonic hedgehog	0.029
Psca	prostate stem cell antigen	0.029
Yap1	yes-associated protein 1	0.029
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.029
Pecam1	platelet/endothelial cell adhesion molecule 1	0.028
Gucy2c	guanylate cyclase 2c	0.028
Prkce	protein kinase C, epsilon	0.027
Col4a3	collagen, type IV, alpha 3	0.027
Drd2	dopamine receptor D2	0.026
Prl2b1	prolactin family 2, subfamily b, member 1	0.026
Mcam	melanoma cell adhesion molecule	0.026
Ihh	Indian hedgehog	0.026
Adam17	a disintegrin and metallopeptidase domain 17	0.025
Src	Rous sarcoma oncogene	0.025
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.024
Mkl2	MKL/myocardin-like 2	0.024
Ren1	renin 1 structural	0.024
Dlg2	discs, large homolog 2 (Drosophila)	0.024
AI118078	expressed sequence AI118078	0.023
Eltd1	EGF, latrophilin seven transmembrane domain containing 1	0.023
Guca2b	guanylate cyclase activator 2b (retina)	0.023
Apc	adenomatosis polyposis coli	0.022
Gabrr2	gamma-aminobutyric acid (GABA) C receptor, subunit rho 2	0.022
Prap1	proline-rich acidic protein 1	0.022
Tgfbr2	transforming growth factor, beta receptor II	0.022
Kdr	kinase insert domain protein receptor	0.022
Pparg	peroxisome proliferator activated receptor gamma	0.022
Ush1c	Usher syndrome 1C homolog (human)	0.022
Vip	vasoactive intestinal polypeptide	0.022
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.022
Nell2	NEL-like 2 (chicken)	0.022
Cga	glycoprotein hormones, alpha subunit	0.022
Cckbr	cholecystokinin B receptor	0.022
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.021
Adra2a	adrenergic receptor, alpha 2a	0.021
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.021
Apoa4	apolipoprotein A-IV	0.021
Pde6g	phosphodiesterase 6G, cGMP-specific, rod, gamma	0.021
Pitpnm1	phosphatidylinositol transfer protein, membrane-associated 1	0.021
Hif1a	hypoxia inducible factor 1, alpha subunit	0.021
Myo7a	myosin VIIA	0.020
Znrf4	zinc and ring finger 4	0.020
Tmprss3	transmembrane protease, serine 3	0.020
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.020
Rundc3a	RUN domain containing 3A	0.020	Rat
Jag1	jagged 1	0.020
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.020
Shc3	src homology 2 domain-containing transforming protein C3	0.019
Ghr	growth hormone receptor	0.019
Tek	endothelial-specific receptor tyrosine kinase	0.019
Nrl	neural retina leucine zipper gene	0.019
Pou4f3	POU domain, class 4, transcription factor 3	0.019
Pten	phosphatase and tensin homolog	0.019
Fgf9	fibroblast growth factor 9	0.019
Pomc	pro-opiomelanocortin-alpha	0.018
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.018
Rgr	retinal G protein coupled receptor	0.018
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.018
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.018
Guca1b	guanylate cyclase activator 1B	0.018
Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	0.018
Zswim6	zinc finger, SWIM domain containing 6	0.018
Itga1	integrin alpha 1	0.018
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.017
Bdkrb2	bradykinin receptor, beta 2	0.017
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.017
Lpl	lipoprotein lipase	0.017
Pde6h	phosphodiesterase 6H, cGMP-specific, cone, gamma	0.017
Nt5e	5' nucleotidase, ecto	0.017
Smad3	MAD homolog 3 (Drosophila)	0.017
Nos2	nitric oxide synthase 2, inducible	0.017
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.017
Ndrg2	N-myc downstream regulated gene 2	0.017
Cdh23	cadherin 23 (otocadherin)	0.016
Adcy9	adenylate cyclase 9	0.016
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	0.016
Reln	reelin	0.016
Pcp2	Purkinje cell protein 2 (L7)	0.016
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.016
Esr2	estrogen receptor 2 (beta)	0.016
Sh2d2a	SH2 domain protein 2A	0.016
Atp4b	ATPase, H+/K+ exchanging, beta polypeptide	0.016
Mef2c	myocyte enhancer factor 2C	0.016
Star	steroidogenic acute regulatory protein	0.016
Gja1	gap junction protein, alpha 1	0.016
Kiss1r	KISS1 receptor	0.016
Spdef	SAM pointed domain containing ets transcription factor	0.016
Obox2	oocyte specific homeobox 2	0.015
Pvrl3	poliovirus receptor-related 3	0.015
Bmp5	bone morphogenetic protein 5	0.015
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.015
Aipl1	aryl hydrocarbon receptor-interacting protein-like 1	0.015
Npy	neuropeptide Y	0.015
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.015
Cryaa	crystallin, alpha A	0.015
Aqp7	aquaporin 7	0.014
Drd4	dopamine receptor D4	0.014
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.014
Gsk3b	glycogen synthase kinase 3 beta	0.014
Prnp	prion protein	0.014
Prkcb	protein kinase C, beta	0.014
Ubxn10	UBX domain protein 10	0.014
Ppy	pancreatic polypeptide	0.014
Sparcl1	SPARC-like 1	0.014
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.014
Cacng7	calcium channel, voltage-dependent, gamma subunit 7	0.014
Gdf15	growth differentiation factor 15	0.014
Gnb4	guanine nucleotide binding protein (G protein), beta 4	0.013
Pex5l	peroxisomal biogenesis factor 5-like	0.013
Ldlr	low density lipoprotein receptor	0.013
Mog	myelin oligodendrocyte glycoprotein	0.013
Fas	Fas (TNF receptor superfamily member 6)	0.013
Tnfrsf8	tumor necrosis factor receptor superfamily, member 8	0.013
Mt1	metallothionein 1	0.013
Lmna	lamin A	0.013
Klf15	Kruppel-like factor 15	0.013
Egfr	epidermal growth factor receptor	0.013
Fshb	follicle stimulating hormone beta	0.013	Mouse
Mmp9	matrix metallopeptidase 9	0.013
Sag	retinal S-antigen	0.013
Myo7b	myosin VIIB	0.013
Pcdh7	protocadherin 7	0.013
Gnb3	guanine nucleotide binding protein (G protein), beta 3	0.013
Nhlh2	nescient helix loop helix 2	0.013
Prss41	protease, serine, 41	0.013
Slc38a3	solute carrier family 38, member 3	0.013
BC089491	cDNA sequence BC089491	0.013
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.013
Icam5	intercellular adhesion molecule 5, telencephalin	0.013
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.013
Foxo3	forkhead box O3	0.013
Hr	hairless	0.013
Zan	zonadhesin	0.013
Kcnip2	Kv channel-interacting protein 2	0.012
Tlr4	toll-like receptor 4	0.012
Krt75	keratin 75	0.012
Psap	prosaposin	0.012
Gnmt	glycine N-methyltransferase	0.012
Gast	gastrin	0.012
Rxra	retinoid X receptor alpha	0.012
4933407C03Rik	RIKEN cDNA 4933407C03 gene	0.012
Cplx3	complexin 3	0.012
Il3	interleukin 3	0.012
Fgf8	fibroblast growth factor 8	0.012
Clrn3	clarin 3	0.012
Papss2	3'-phosphoadenosine 5'-phosphosulfate synthase 2	0.012
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.012
Epas1	endothelial PAS domain protein 1	0.012
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.012
Egln1	EGL nine homolog 1 (C. elegans)	0.012
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.012
Degs2	degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase	0.012
Pde10a	phosphodiesterase 10A	0.012	Mouse Rat
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.011
Tcp11	t-complex protein 11	0.011
Moxd2	monooxygenase, DBH-like 2	0.011
Hlf	hepatic leukemia factor	0.011
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.011
Cacna1f	calcium channel, voltage-dependent, alpha 1F subunit	0.011
BC021785	cDNA sequence BC021785	0.011
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.011
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.011
Selp	selectin, platelet	0.011
Clcnka	chloride channel Ka	0.011
Gas7	growth arrest specific 7	0.011
Mzf1	myeloid zinc finger 1	0.011
Pde6b	phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide	0.011	Mouse
Cbs	cystathionine beta-synthase	0.011
Npas1	neuronal PAS domain protein 1	0.011
Cav1	caveolin 1, caveolae protein	0.011
Plaur	plasminogen activator, urokinase receptor	0.011
Thbs2	thrombospondin 2	0.011
Hesx1	homeobox gene expressed in ES cells	0.011
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.011
Pdzk1	PDZ domain containing 1	0.011
Isl1	ISL1 transcription factor, LIM/homeodomain	0.011
Ahr	aryl-hydrocarbon receptor	0.011
Grk1	G protein-coupled receptor kinase 1	0.011
Chrd	chordin	0.011
Rd3	retinal degeneration 3	0.011
Fbxo2	F-box protein 2	0.011
B4galnt2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.011
Sectm1b	secreted and transmembrane 1B	0.011
Gfap	glial fibrillary acidic protein	0.011
Mdm2	transformed mouse 3T3 cell double minute 2	0.011
Ppard	peroxisome proliferator activator receptor delta	0.011
Soat1	sterol O-acyltransferase 1	0.011
Rgs5	regulator of G-protein signaling 5	0.011
Stk30	serine/threonine kinase 30	0.011
Rbp3	retinol binding protein 3, interstitial	0.011
Dpp6	dipeptidylpeptidase 6	0.011
Ptprm	protein tyrosine phosphatase, receptor type, M	0.011
Gip	gastric inhibitory polypeptide	0.010
Zfp787	zinc finger protein 787	0.010
Srrm4	serine/arginine repetitive matrix 4	0.010
Taok1	TAO kinase 1	0.010
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.010
Fbln1	fibulin 1	0.010
Nrip3	nuclear receptor interacting protein 3	0.010
S1pr1	sphingosine-1-phosphate receptor 1	0.010
Ankrd33	ankyrin repeat domain 33	0.010
Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	0.010
Slc5a11	solute carrier family 5 (sodium/glucose cotransporter), member 11	0.010
Pcsk2	proprotein convertase subtilisin/kexin type 2	0.010
Acvr1	activin A receptor, type 1	0.010
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.010