IMP

Process View

Mus musculus

11 genes annotated in mouse

Multi-species View

establishment of melanosome localization

GO:0032401

The directed movement of a melanosome to a specific location.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "establishment of melanosome localization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "establishment of melanosome localization" (in gray)

Name	Description	Probability	Func Analog Organism
Bbs4	Bardet-Biedl syndrome 4 (human)	1.000	Zebrafish
Lyst	lysosomal trafficking regulator	1.000
Bbs1	Bardet-Biedl syndrome 1 (human)	1.000
Bbs2	Bardet-Biedl syndrome 2 (human)	1.000	Zebrafish
Hps1	Hermansky-Pudlak syndrome 1 homolog (human)	0.996
Ap3b1	adaptor-related protein complex 3, beta 1 subunit	0.996
Mitf	microphthalmia-associated transcription factor	0.996
Mlph	melanophilin	0.996
Rab27a	RAB27A, member RAS oncogene family	0.994
Hps5	Hermansky-Pudlak syndrome 5 homolog (human)	0.993
Cno	cappuccino	0.993
a	nonagouti	0.979
Hps6	Hermansky-Pudlak syndrome 6	0.926
Tyrp1	tyrosinase-related protein 1	0.718
Oca2	oculocutaneous albinism II	0.704
Arl6	ADP-ribosylation factor-like 6	0.697	Zebrafish
Ap3d1	adaptor-related protein complex 3, delta 1 subunit	0.617
Bbs5	Bardet-Biedl syndrome 5 (human)	0.570
Stx12	syntaxin 12	0.546
Ttc8	tetratricopeptide repeat domain 8	0.492
Prf1	perforin 1 (pore forming protein)	0.460
Muted	muted	0.458
Tyr	tyrosinase	0.449
Csnk1g2	casein kinase 1, gamma 2	0.435
Vapa	vesicle-associated membrane protein, associated protein A	0.404
Mapk3	mitogen-activated protein kinase 3	0.382
Bbs9	Bardet-Biedl syndrome 9 (human)	0.350
Rab38	RAB38, member of RAS oncogene family	0.341
Sh3glb2	SH3-domain GRB2-like endophilin B2	0.329
Nptn	neuroplastin	0.326
Add1	adducin 1 (alpha)	0.321
Fbxw5	F-box and WD-40 domain protein 5	0.315
Rheb	Ras homolog enriched in brain	0.294
Rab11a	RAB11a, member RAS oncogene family	0.266
Bbs7	Bardet-Biedl syndrome 7 (human)	0.263
Hps3	Hermansky-Pudlak syndrome 3 homolog (human)	0.251
Atp6v1d	ATPase, H+ transporting, lysosomal V1 subunit D	0.247
Pldn	pallidin	0.236	Human
Tmem30a	transmembrane protein 30A	0.227
Drap1	Dr1 associated protein 1 (negative cofactor 2 alpha)	0.217
Dstn	destrin	0.213
Pef1	penta-EF hand domain containing 1	0.207
Dctn2	dynactin 2	0.195
Sytl5	synaptotagmin-like 5	0.187
Hps4	Hermansky-Pudlak syndrome 4 homolog (human)	0.179
Atp6v0d1	ATPase, H+ transporting, lysosomal V0 subunit D1	0.169
Aes	amino-terminal enhancer of split	0.164
Atp6v1c1	ATPase, H+ transporting, lysosomal V1 subunit C1	0.159
Mobkl3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.120
Mlf2	myeloid leukemia factor 2	0.120
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.118
Dctn1	dynactin 1	0.118
Pi4kb	phosphatidylinositol 4-kinase, catalytic, beta polypeptide	0.115
Anapc2	anaphase promoting complex subunit 2	0.114
Exoc7	exocyst complex component 7	0.109
Kit	kit oncogene	0.097
Fkbp8	FK506 binding protein 8	0.095
Stx7	syntaxin 7	0.092
Arl1	ADP-ribosylation factor-like 1	0.083
Pld3	phospholipase D family, member 3	0.083
Capns1	calpain, small subunit 1	0.081
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.080
Spna2	spectrin alpha 2	0.076
Oaz2-ps	ornithine decarboxylase antizyme 2, pseudogene	0.073
Chmp2b	chromatin modifying protein 2B	0.072
8430410K20Rik	RIKEN cDNA 8430410K20 gene	0.072
Clptm1	cleft lip and palate associated transmembrane protein 1	0.069
Pmel	premelanosome protein	0.069
Ptov1	prostate tumor over expressed gene 1	0.069
Bag6	BCL2-associated athanogene 6	0.066
Mtch1	mitochondrial carrier homolog 1 (C. elegans)	0.065
Stx11	syntaxin 11	0.064
Tmem9b	TMEM9 domain family, member B	0.063
Pomc	pro-opiomelanocortin-alpha	0.063
Dnajb9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.060
Ccdc64	coiled-coil domain containing 64	0.060
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.059
Wsb2	WD repeat and SOCS box-containing 2	0.056
Fmn1	formin 1	0.055
Bsg	basigin	0.053
Ins2	insulin II	0.052
Chmp5	chromatin modifying protein 5	0.052
Vps4a	vacuolar protein sorting 4a (yeast)	0.052
Tmco1	transmembrane and coiled-coil domains 1	0.050
Aamp	angio-associated migratory protein	0.049
Atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.049
Ap2m1	adaptor protein complex AP-2, mu1	0.049
Rab6	RAB6, member RAS oncogene family	0.048
Mtmr6	myotubularin related protein 6	0.046
Mkks	McKusick-Kaufman syndrome protein	0.044	Zebrafish
Snx16	sorting nexin 16	0.044
Akap8l	A kinase (PRKA) anchor protein 8-like	0.044
Rnf103	ring finger protein 103	0.043
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.043
Hdac5	histone deacetylase 5	0.042
Plcg1	phospholipase C, gamma 1	0.041
Prr15	proline rich 15	0.040
Klc1	kinesin light chain 1	0.040
Ubl7	ubiquitin-like 7 (bone marrow stromal cell-derived)	0.040
Rab25	RAB25, member RAS oncogene family	0.038	Mouse
Med16	mediator complex subunit 16	0.038
Ggt1	gamma-glutamyltransferase 1	0.038
Arl8b	ADP-ribosylation factor-like 8B	0.038
Rab28	RAB28, member RAS oncogene family	0.037
Mc1r	melanocortin 1 receptor	0.036
Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B	0.035
Slc24a5	solute carrier family 24, member 5	0.035
Chmp1b	chromatin modifying protein 1B	0.034
Cltc	clathrin, heavy polypeptide (Hc)	0.033
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.033
Grb7	growth factor receptor bound protein 7	0.033
Rab2a	RAB2A, member RAS oncogene family	0.033
Abhd12	abhydrolase domain containing 12	0.032
Napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha	0.031
Fam83g	family with sequence similarity 83, member G	0.031
Cldn2	claudin 2	0.031
Selk	selenoprotein K	0.030
Wbp2	WW domain binding protein 2	0.029
Btbd10	BTB (POZ) domain containing 10	0.029
Dtnbp1	dystrobrevin binding protein 1	0.029
2410004B18Rik	RIKEN cDNA 2410004B18 gene	0.029
Gipc1	GIPC PDZ domain containing family, member 1	0.028
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.028
Sgta	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.028
Egln2	EGL nine homolog 2 (C. elegans)	0.028
Pfn2	profilin 2	0.027
Elf3	E74-like factor 3	0.027
Trappc6b	trafficking protein particle complex 6B	0.027
Cript	cysteine-rich PDZ-binding protein	0.026
Gabarap	gamma-aminobutyric acid receptor associated protein	0.026
Ndfip1	Nedd4 family interacting protein 1	0.026
Eid1	EP300 interacting inhibitor of differentiation 1	0.026
Flot1	flotillin 1	0.025
Max	Max protein	0.025
Stub1	STIP1 homology and U-Box containing protein 1	0.025
Nudt3	nudix (nucleotide diphosphate linked moiety X)-type motif 3	0.025
Fastk	Fas-activated serine/threonine kinase	0.025
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.024
Golph3	golgi phosphoprotein 3	0.024
Thra	thyroid hormone receptor alpha	0.024
AI837181	expressed sequence AI837181	0.024
Slc25a11	solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11	0.024
Rab5a	RAB5A, member RAS oncogene family	0.024	Mouse
Fgfbp1	fibroblast growth factor binding protein 1	0.023
Pex19	peroxisomal biogenesis factor 19	0.023
Cpeb4	cytoplasmic polyadenylation element binding protein 4	0.023
Dync1h1	dynein cytoplasmic 1 heavy chain 1	0.022
Rab21	RAB21, member RAS oncogene family	0.022	Mouse
Abr	active BCR-related gene	0.022
Chmp4b	chromatin modifying protein 4B	0.022
Rab27b	RAB27b, member RAS oncogene family	0.022	Mouse
Golga7	golgi autoantigen, golgin subfamily a, 7	0.022
Galk2	galactokinase 2	0.021
Ube2a	ubiquitin-conjugating enzyme E2A, RAD6 homolog (S. cerevisiae)	0.021
Ift74	intraflagellar transport 74 homolog (Chlamydomonas)	0.021
Arl6ip5	ADP-ribosylation factor-like 6 interacting protein 5	0.021
Bloc1s3	biogenesis of lysosome-related organelles complex-1, subunit 3	0.021
Rabac1	Rab acceptor 1 (prenylated)	0.021
Tspyl4	TSPY-like 4	0.020
Pgrmc1	progesterone receptor membrane component 1	0.020
Kdelr1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	0.020
Ttc30b	tetratricopeptide repeat domain 30B	0.020
Map1lc3a	microtubule-associated protein 1 light chain 3 alpha	0.020
Atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.020
Pitpna	phosphatidylinositol transfer protein, alpha	0.020
Prss8	protease, serine, 8 (prostasin)	0.019
Vps26b	vacuolar protein sorting 26 homolog B (yeast)	0.019
Flot2	flotillin 2	0.019
Bcl7b	B-cell CLL/lymphoma 7B	0.019
Klhl2	kelch-like 2, Mayven (Drosophila)	0.018
Rab18	RAB18, member RAS oncogene family	0.018
Cdk5	cyclin-dependent kinase 5	0.018
Mapk13	mitogen-activated protein kinase 13	0.018
Pde6d	phosphodiesterase 6D, cGMP-specific, rod, delta	0.018
Car5a	carbonic anhydrase 5a, mitochondrial	0.018
Sox15	SRY-box containing gene 15	0.018
Caml	calcium modulating ligand	0.018
Sntb1	syntrophin, basic 1	0.018
Golga2	golgi autoantigen, golgin subfamily a, 2	0.018
Hspa4l	heat shock protein 4 like	0.017
Crb3	crumbs homolog 3 (Drosophila)	0.017
Vps29	vacuolar protein sorting 29 (S. pombe)	0.017
Vamp4	vesicle-associated membrane protein 4	0.017
Tusc3	tumor suppressor candidate 3	0.017
Tmem33	transmembrane protein 33	0.017
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.017
Sirt2	sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)	0.017
Obfc2b	oligonucleotide/oligosaccharide-binding fold containing 2B	0.017
Acsl4	acyl-CoA synthetase long-chain family member 4	0.017
Sult2b1	sulfotransferase family, cytosolic, 2B, member 1	0.016
Ift172	intraflagellar transport 172 homolog (Chlamydomonas)	0.016
Scoc	short coiled-coil protein	0.016
Calm1	calmodulin 1	0.016
Cc2d1a	coiled-coil and C2 domain containing 1A	0.016
Ap1m2	adaptor protein complex AP-1, mu 2 subunit	0.016
Cab39	calcium binding protein 39	0.016
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.016
Ccdc104	coiled-coil domain containing 104	0.016
Akirin1	akirin 1	0.016
Vamp2	vesicle-associated membrane protein 2	0.015
Cldn3	claudin 3	0.015
L1cam	L1 cell adhesion molecule	0.015
Tesk1	testis specific protein kinase 1	0.015
2410001C21Rik	RIKEN cDNA 2410001C21 gene	0.015
Rtn4	reticulon 4	0.015
Chmp1a	chromatin modifying protein 1A	0.015
1500031L02Rik	RIKEN cDNA 1500031L02 gene	0.015
Ube2d3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.015
Kif3b	kinesin family member 3B	0.015
Oxsm	3-oxoacyl-ACP synthase, mitochondrial	0.015
Pdcd10	programmed cell death 10	0.014
Btbd2	BTB (POZ) domain containing 2	0.014
Ptp4a1	protein tyrosine phosphatase 4a1	0.014
Gjb5	gap junction protein, beta 5	0.014
Rab1b	RAB1B, member RAS oncogene family	0.014	Mouse
Grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.014
6330409N04Rik	RIKEN cDNA 6330409N04 gene	0.014
Ehf	ets homologous factor	0.014
Rab7	RAB7, member RAS oncogene family	0.013
Tmprss2	transmembrane protease, serine 2	0.013
Tprgl	transformation related protein 63 regulated like	0.013
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.013
Cldn7	claudin 7	0.013
Vps35	vacuolar protein sorting 35	0.013
Mapre3	microtubule-associated protein, RP/EB family, member 3	0.013
Phlda2	pleckstrin homology-like domain, family A, member 2	0.013
Nipa2	non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)	0.013
Ergic3	ERGIC and golgi 3	0.013
Lrrc57	leucine rich repeat containing 57	0.013
Limk2	LIM motif-containing protein kinase 2	0.013
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.013
Rnf5	ring finger protein 5	0.013
S100a14	S100 calcium binding protein A14	0.013
Atp6v1g1	ATPase, H+ transporting, lysosomal V1 subunit G1	0.013
Atp9a	ATPase, class II, type 9A	0.013
Zfp185	zinc finger protein 185	0.013
Unc50	unc-50 homolog (C. elegans)	0.013
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.012
Flii	flightless I homolog (Drosophila)	0.012
Ifrd1	interferon-related developmental regulator 1	0.012
Chac2	ChaC, cation transport regulator homolog 2 (E. coli)	0.012
Smarcc2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.012
Trim13	tripartite motif-containing 13	0.012
Pmm1	phosphomannomutase 1	0.012
Fcgbp	Fc fragment of IgG binding protein	0.012
Ube3b	ubiquitin protein ligase E3B	0.012
Thrb	thyroid hormone receptor beta	0.012
Sec23a	SEC23A (S. cerevisiae)	0.012
Ocln	occludin	0.012
Plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	0.012
Mpzl2	myelin protein zero-like 2	0.012
Ubxn6	UBX domain protein 6	0.012
Dnajc12	DnaJ (Hsp40) homolog, subfamily C, member 12	0.012
9130011J15Rik	RIKEN cDNA 9130011J15 gene	0.012
Myo5a	myosin VA	0.012
Rbbp9	retinoblastoma binding protein 9	0.012
Rnf115	ring finger protein 115	0.012
Rap1b	RAS related protein 1b	0.012
Nsf	N-ethylmaleimide sensitive fusion protein	0.012
Fam83f	family with sequence similarity 83, member F	0.012
Csnk1e	casein kinase 1, epsilon	0.012
Arl8a	ADP-ribosylation factor-like 8A	0.012
2810422J05Rik	RIKEN cDNA 2810422J05 gene	0.011
Gna11	guanine nucleotide binding protein, alpha 11	0.011
Rapsn	receptor-associated protein of the synapse	0.011
Slc44a4	solute carrier family 44, member 4	0.011
Rtn3	reticulon 3	0.011
Supt5h	suppressor of Ty 5 homolog (S. cerevisiae)	0.011
Hoxd4	homeobox D4	0.011
Elf5	E74-like factor 5	0.011
Cby1	chibby homolog 1 (Drosophila)	0.011
Otp	orthopedia homolog (Drosophila)	0.011
Homer1	homer homolog 1 (Drosophila)	0.011
Fbxo33	F-box protein 33	0.011
Mgat3	mannoside acetylglucosaminyltransferase 3	0.011
Tmbim6	transmembrane BAX inhibitor motif containing 6	0.011
Bre	brain and reproductive organ-expressed protein	0.011
Cyth2	cytohesin 2	0.011
Akt1	thymoma viral proto-oncogene 1	0.011
Cerk	ceramide kinase	0.011
Vps33b	vacuolar protein sorting 33B (yeast)	0.011
Dync2li1	dynein cytoplasmic 2 light intermediate chain 1	0.011
Atg3	autophagy-related 3 (yeast)	0.011
Galnt3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3	0.011
Tctex1d2	Tctex1 domain containing 2	0.011
Nrbf2	nuclear receptor binding factor 2	0.011
Krt12	keratin 12	0.011
Dync1i2	dynein cytoplasmic 1 intermediate chain 2	0.011
Ly6g6d	lymphocyte antigen 6 complex, locus G6D	0.011
4930455F23Rik	RIKEN cDNA 4930455F23 gene	0.011
Mgrn1	mahogunin, ring finger 1	0.011
Dynll2	dynein light chain LC8-type 2	0.011
Resp18	regulated endocrine-specific protein 18	0.011
Uso1	USO1 homolog, vesicle docking protein (yeast)	0.010
Chrm5	cholinergic receptor, muscarinic 5	0.010
C78339	expressed sequence C78339	0.010
Car12	carbonic anyhydrase 12	0.010
Efhc1	EF-hand domain (C-terminal) containing 1	0.010
Nf2	neurofibromatosis 2	0.010
Trappc10	trafficking protein particle complex 10	0.010
Mia1	melanoma inhibitory activity 1	0.010
Hivep1	human immunodeficiency virus type I enhancer binding protein 1	0.010
Hmgn3	high mobility group nucleosomal binding domain 3	0.010
0610031J06Rik	RIKEN cDNA 0610031J06 gene	0.010
Hccs	holocytochrome c synthetase	0.010
Rnf167	ring finger protein 167	0.010
Slc45a2	solute carrier family 45, member 2	0.010