IMP

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Danio rerio

1 genes annotated in zebrafish

neuron remodeling

The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neuron remodeling"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "neuron remodeling" (in gray)

Name	Description	Probability	Func Analog Organism
igf1rb	insulin-like growth factor 1b receptor	0.310	Fly
aplp2	amyloid beta (A4) precursor-like protein 2	0.192
insrb	insulin receptor b	0.189	Fly
h1m	linker histone H1M	0.139
thrb	thyroid hormone receptor beta	0.105
vdra	vitamin D receptor a	0.105
prnprs3	prion protein, related sequence 3	0.095
robo1	roundabout homolog 1	0.082
kop	askopos	0.078
ved	ventrally expressed dharma/bozozok antagonist	0.071
zeb2a	zinc finger E-box binding homeobox 2a	0.064
sox11b	SRY-box containing gene 11b	0.059
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.058
otx5	orthodenticle homolog 5	0.056
snap29	synaptosomal-associated protein 29	0.054
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.043
zgc:55843	zgc:55843	0.042
bactin1	bactin1	0.042
dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)	0.041
fmr1	fragile X mental retardation 1	0.041
arid4a	AT rich interactive domain 4A (RBP1-like)	0.039
lpin1	lipin 1	0.038
kif5aa	kinesin family member 5A, a	0.034
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.034
slit1a	slit homolog 1a (Drosophila)	0.033
klhl11	kelch-like 11 (Drosophila)	0.033
tbc1d23	TBC1 domain family, member 23	0.032
fcho2	FCH domain only 2	0.031
spred1	sprouty-related, EVH1 domain containing 1	0.031
wnt10a	wingless-type MMTV integration site family, member 10a	0.031
birc2	baculoviral IAP repeat-containing 2	0.031
greb1	growth regulation by estrogen in breast cancer 1	0.030
atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.030
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.029
piwil2	piwi-like 2 (Drosophila)	0.029
zgc:55936	zgc:55936	0.029
sirt1	sirtuin (silent mating type information regulation 2 homolog) 1	0.029
si:ch211-239j15.4	si:ch211-239j15.4	0.028
traf4a	tnf receptor-associated factor 4a	0.028
zgc:101761	zgc:101761	0.027
insra	insulin receptor a	0.027	Fly
ankrd12	ankyrin repeat domain 12	0.027
dlg2	discs, large (Drosophila) homolog 2	0.027
znf148	zinc finger protein 148	0.026
mapk3	mitogen-activated protein kinase 3	0.026
cnot6	CCR4-NOT transcription complex, subunit 6	0.026
kif5bb	kinesin family member 5B, b	0.026
stau1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.026
runx1	runt-related transcription factor 1	0.026
polb	polymerase (DNA directed), beta	0.025
im:7163520	im:7163520	0.025
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.025
tgfbi	transforming growth factor, beta-induced	0.025
tcf12	transcription factor 12	0.025
kdm5c	lysine (K)-specific demethylase 5C	0.024
rmnd5b	required for meiotic nuclear division 5 homolog B (S. cerevisiae)	0.024
lhx2b	LIM homeobox 2b	0.024
acsl1	acyl-CoA synthetase long-chain family member 1	0.024
bfb	complement component bfb	0.024
crx	cone-rod homeobox	0.023
eno2	enolase 2	0.023
tdrd1	tudor domain containing 1	0.023
ulk2	unc-51-like kinase 2 (C. elegans)	0.023
ptk2.1	protein tyrosine kinase 2a	0.022
hmx1	H6 homeo box 1	0.022
irf2bp2a	interferon regulatory factor 2 binding protein 2a	0.022
casc3	cancer susceptibility candidate 3	0.022
dirc2	disrupted in renal carcinoma 2	0.022
bmpr2b	bone morphogenetic protein receptor, type II b (serine/threonine kinase)	0.022
igf1	insulin-like growth factor 1	0.022
zgc:64076	zgc:64076	0.022
sec24c	SEC24 family, member C (S. cerevisiae)	0.022
celsr1b	cadherin EGF LAG seven-pass G-type receptor 1b	0.021
ndrg1l	N-myc downstream regulated gene 1, like	0.021
tubb5	tubulin, beta 5	0.021
ankrd6	ankyrin repeat domain 6	0.021
per3	period homolog 3 (Drosophila)	0.021
zgc:66242	zgc:66242	0.020
rps6kal	ribosomal protein S6 kinase, like	0.020
spry1	sprouty homolog 1 (Drosophila)	0.020
ldb1a	LIM-domain binding factor 1a	0.020
ncoa2	nuclear receptor coactivator 2	0.020
otx2	orthodenticle homolog 2	0.020
itgb1b.2	integrin, beta 1b.2	0.020
acvr1b	activin A receptor, type IB	0.020
helb	helicase (DNA) B	0.020
antxr1	anthrax toxin receptor 1	0.020
foxo3b	forkhead box O3b	0.020
mapk4	mitogen-activated protein kinase 4	0.020
robo2	roundabout homolog 2	0.020
rlf	rearranged L-myc fusion	0.020
zgc:112180	zgc:112180	0.020
rab11fip4a	RAB11 family interacting protein 4 (class II) a	0.019
zgc:73290	zgc:73290	0.018
zbtb4	zinc finger and BTB domain containing 4	0.018
ptena	phosphatase and tensin homolog A	0.018	Fly
usp4	ubiquitin specific protease 4 (proto-oncogene)	0.018
gria3b	glutamate receptor, ionotrophic, AMPA 3b	0.018
frmd6	FERM domain containing 6	0.018
spry2	sprouty homolog 2	0.018
gdi2	GDP dissociation inhibitor 2	0.018
angptl3	angiopoietin-like 3	0.018
LOC566708	FL cytokine receptor-like	0.018
il1rapl2	interleukin 1 receptor accessory protein-like 2	0.018
zmynd19	zinc finger, MYND domain containing 19	0.017
rabgef1l	RAB guanine nucleotide exchange factor (GEF) 1, like	0.017
tgif1	TGFB-induced factor homeobox 1	0.017
ubr5	ubiquitin protein ligase E3 component n-recognin 5	0.017
cp	ceruloplasmin	0.017
epn1	epsin 1	0.017
flot2a	flotillin 2a	0.017
itgav	integrin, alpha V	0.017
midn	midnolin	0.017
wu:fi25h02	wu:fi25h02	0.017
LOC555504	novel protocadherin protein	0.017
LOC559976	similar to glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.017
taf1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.017
syk	spleen tyrosine kinase	0.017
pspc1	paraspeckle component 1	0.016
blm	Bloom syndrome	0.016
kidins220b	kinase D-interacting substrate of 220b	0.016
snx27	sorting nexin family member 27	0.016
tlr21	toll-like receptor 21	0.016
ext1b	exostoses (multiple) 1b	0.016
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.016
mecp2	methyl CpG binding protein 2	0.016
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.016
zgc:171872	zgc:171872	0.016
pdcd2	programmed cell death 2	0.016
vsx1	visual system homeobox 1 homolog, chx10-like	0.016
atf4b2	activating transcription factor 4b2	0.016
aars	alanyl-tRNA synthetase	0.016
zgc:63629	zgc:63629	0.016
vps26bl	vacuolar protein sorting 26 homolog B, like	0.016
ubin	ataxin-1 ubiquitin-like interacting protein	0.016
spna2	spectrin alpha 2	0.015
map2k4a	mitogen-activated protein kinase kinase 4a	0.015
ripply1	ripply1	0.015
b4galt6	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6	0.015
bsg	basigin	0.015
mxi1	max interacting protein	0.015
wu:fb76c12	wu:fb76c12	0.015
trim3a	tripartite motif-containing 3a	0.015
cntfr	ciliary neurotrophic factor receptor	0.015
gsk3b	glycogen synthase kinase 3 beta	0.015
rorb	RAR-related orphan receptor B	0.015
ing3	inhibitor of growth family, member 3	0.015
exoc7	exocyst complex component 7	0.015
pknox1.1	pbx/knotted 1 homeobox 1.1	0.015
foxo3a	forkhead box O3A	0.015
aanat2	arylalkylamine N-acetyltransferase	0.015
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.015
cecr1a	cat eye syndrome chromosome region, candidate 1a	0.015
pld1a	phospholipase D1a	0.014
mapk14b	mitogen-activated protein kinase 14b	0.014
zgc:162270	zgc:162270	0.014
igf1ra	insulin-like growth factor 1a receptor	0.014	Fly
furinb	furin (paired basic amino acid cleaving enzyme) b	0.014
ncor2	nuclear receptor co-repressor 2	0.014
coro1b	coronin, actin binding protein, 1B	0.014
ythdf3	YTH domain family 3	0.014
foxg1a	forkhead box G1a	0.014
tmem147	transmembrane protein 147	0.014
rcv1	recoverin	0.014
polrmt	polymerase (RNA) mitochondrial (DNA directed)	0.014
ints6	integrator complex subunit 6	0.014
ptpra	protein tyrosine phosphatase, receptor type, A	0.014
ap1g1	adaptor-related protein complex 1, gamma 1 subunit	0.014
polr2d	polymerase (RNA) II (DNA directed) polypeptide D	0.014
atoh7	atonal homolog 7	0.014
ccnt2a	cyclin T2a	0.014
lingo1b	leucine rich repeat and Ig domain containing 1b	0.014
ap2a1	adaptor-related protein complex 2, alpha 1 subunit	0.014
stam	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.014
golim4b	golgi integral membrane protein 4b	0.014
masp2	mannan-binding lectin serine peptidase 2	0.014
nadl1.2	neural adhesion molecule L1.2	0.014
si:ch211-59d15.5	si:ch211-59d15.5	0.014
glcea	glucuronyl C5-epimerase a	0.014
wars	tryptophanyl-tRNA synthetase	0.014
med27	mediator complex subunit 27	0.014
sart3	squamous cell carcinoma antigen recognised by T cells 3	0.013
per2	period homolog 2 (Drosophila)	0.013
gnb2l1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	0.013
sept6	septin 6	0.013
dixdc1a	DIX domain containing 1a	0.013
col17a1a	collagen, type XVII, alpha 1a	0.013
cry3	cryptochrome 3	0.013
ndufa6	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6	0.013
eomesa	eomesodermin homolog a	0.013
il1rapl1a	interleukin 1 receptor accessory protein-like 1a	0.013
ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.013
ca15b	carbonic anhydrase XV b	0.013
hmgb1a	high-mobility group box 1a	0.013
smg7	Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)	0.013
kctd15a	potassium channel tetramerisation domain containing 15a	0.013
wu:fq41a10	wu:fq41a10	0.013
setd5	SET domain containing 5	0.013
sept3	septin 3	0.013
si:ch1073-351m12.1	si:ch1073-351m12.1	0.013
usp33	ubiquitin specific peptidase 33	0.013
grk7a	G-protein-coupled receptor kinase 7a	0.013
arr3a	arrestin 3a, retinal (X-arrestin)	0.013
atl3	atlastin 3	0.013
zgc:152785	zgc:152785	0.013
ggps1	geranylgeranyl diphosphate synthase 1	0.013
cyp51	cytochrome P450, family 51	0.013
si:dkey-97i18.2	si:dkey-97i18.2	0.013
xpo6	exportin 6	0.013
mpp6b	membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)	0.013
st8sia5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	0.013
si:ch211-192p3.1	si:ch211-192p3.1	0.013
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.013
im:6907928	im:6907928	0.013
sirt6	sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)	0.013
hspb9	heat shock protein, alpha-crystallin-related, 9	0.013
nptx2b	neuronal pentraxin 2b	0.012
il15l	interleukin 15, like	0.012
xrn1	5'-3' exoribonuclease 1	0.012
robo3	roundabout homolog 3	0.012
si:dkey-76b14.4	si:dkey-76b14.4	0.012
arfgef1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.012
gsna	gelsolin a	0.012
zgc:77051	zgc:77051	0.012
raver1	ribonucleoprotein, PTB-binding 1	0.012
ero1l	ERO1-like (S. cerevisiae)	0.012
mbnl2	muscleblind-like 2 (Drosophila)	0.012
LOC565106	novel protein similar to vertebrate calpain 1 (CAPN1)	0.012
skia	nuclear oncoprotein skia	0.012
ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.012
zgc:86609	zgc:86609	0.012
tgm2b	transglutaminase 2b	0.012
fgf20a	fibroblast growth factor 20a	0.012
dlg1	discs, large (Drosophila) homolog 1	0.012
ptpn13	protein tyrosine phosphatase, non-receptor type 13	0.012
fxc1	fracture callus 1 homolog (rat)	0.012
casp9	caspase 9, apoptosis-related cysteine protease	0.012
maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)	0.012
zgc:172161	zgc:172161	0.012
ppdpfb	pancreatic progenitor cell differentiation and proliferation factor b	0.012
foxp2	forkhead box P2	0.012
hpca	hippocalcin	0.012
btbd6b	BTB (POZ) domain containing 6b	0.012
ccr7	chemokine (C-C motif) receptor 7	0.012
ppp2r5d	protein phosphatase 2, regulatory subunit B', delta	0.012
rbbp6	retinoblastoma binding protein 6	0.012
cul3a	cullin 3a	0.012
slc30a2	solute carrier family 30 (zinc transporter), member 2	0.012
tada3l	transcriptional adaptor 3 (NGG1 homolog, yeast)-like	0.012
LOC794630	retinol-binding protein 3-like	0.012
march5l	membrane-associated ring finger (C3HC4) 5, like	0.012
flot1	flotillin 1	0.012
zeb2b	zinc finger E-box binding homeobox 2b	0.012
elovl6	ELOVL family member 6, elongation of long chain fatty acids (yeast)	0.012
cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.012
vps35	vacuolar protein sorting 35 (yeast)	0.012
akt2	v-akt murine thymoma viral oncogene homolog 2	0.012
gnat2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.012
si:dkeyp-94b4.2	si:dkeyp-94b4.2	0.012
myst2	MYST histone acetyltransferase 2	0.012
jak1	Janus kinase 1	0.012
tuba1l	tubulin, alpha 1, like	0.012
dkk1b	dickkopf 1b	0.012
rnf14	ring finger protein 14	0.012
arntl1a	aryl hydrocarbon receptor nuclear translocator-like 1a	0.012
zfyve28	zinc finger, FYVE domain containing 28	0.012
trim8	tripartite motif-containing 8	0.012
ep300b	E1A binding protein p300 b	0.012
lpp	LIM domain containing preferred translocation partner in lipoma	0.012
zorba	Orb/CPEB-related RNA-binding protein	0.012
abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.012
sas	sarcoma amplified sequence	0.012
gro2	groucho 2	0.012
tnikb	TRAF2 and NCK interacting kinase b	0.012
cfl2l	cofilin 2, like	0.012
dcun1d1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.012
skap2	src kinase associated phosphoprotein 2	0.011
im:7150573	im:7150573	0.011
dopey2	dopey family member 2	0.011
appl1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.011
her11	hairy-related 11	0.011
lmbrd2a	LMBR1 domain containing 2a	0.011
fut10	fucosyltransferase 10	0.011
arntl1b	aryl hydrocarbon receptor nuclear translocator-like 1b	0.011
brap	BRCA1 associated protein	0.011
ankrd13c	ankyrin repeat domain 13C	0.011
mark3	MAP/microtubule affinity-regulating kinase 3	0.011
ftsjd1	FtsJ methyltransferase domain containing 1	0.011
henmt1	HEN1 methyltransferase homolog 1 (Arabidopsis)	0.011
arl6	ADP-ribosylation factor-like 6	0.011
sort1a	sortilin 1a	0.011
si:dkey-77a20.7	si:dkey-77a20.7	0.011
crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.011
cflar	CASP8 and FADD-like apoptosis regulator	0.011
tfe3a	transcription factor binding to IGHM enhancer 3a	0.011
parn	poly(A)-specific ribonuclease (deadenylation nuclease)	0.011
epc2	enhancer of polycomb homolog 2 (Drosophila)	0.011
sema3fb	semaphorin 3fb	0.011
appbp2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	0.011
ccdc94	coiled-coil domain containing 94	0.011
sdcbp	syndecan binding protein (syntenin)	0.011
traf6	TNF receptor-associated factor 6	0.011
hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.011
tnrc6b	trinucleotide repeat containing 6B	0.011
narf	nuclear prelamin A recognition factor	0.011
herpud2	HERPUD family member 2	0.011
atxn7l3	ataxin 7-like 3	0.011
slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.011
nr1d1	nuclear receptor subfamily 1, group d, member 1	0.011
oc90	otoconin 90	0.011
fam168a	family with sequence similarity 168, member A	0.011
zgc:152900	zgc:152900	0.011
si:ch211-69i14.7	si:ch211-69i14.7	0.011
abcg2c	ATP-binding cassette, sub-family G (WHITE), member 2c	0.011
syne1a	spectrin repeat containing, nuclear envelope 1a	0.011
slc25a40	solute carrier family 25, member 40	0.011
cacnb2b	calcium channel, voltage-dependent, beta 2b	0.011
rtn1a	reticulon 1a	0.011
cmtm7	CKLF-like MARVEL transmembrane domain containing 7	0.011
cnot1	CCR4-NOT transcription complex, subunit 1	0.011
mrpl14	mitochondrial ribosomal protein L14	0.011
zgc:92566	zgc:92566	0.011
fyna	FYN oncogene related to SRC, FGR, YES a	0.011
hs3st3b1a	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a	0.011
pofut2	protein O-fucosyltransferase 2	0.011
crfb7	cytokine receptor family member b7	0.011
eya2	eyes absent homolog 2 (Drosophila)	0.011
trim13	tripartite motif-containing 13	0.011
xpnpep3	X-prolyl aminopeptidase (aminopeptidase P) 3, putative	0.011
tmem198b	transmembrane protein 198b	0.011
mst1rb	macrophage stimulating 1 receptor (c-met-related tyrosine kinase), b	0.011
adcy5	adenylate cyclase 5	0.011
sb:cb8	sb:cb8	0.011
rhoh	ras homolog gene family, member H	0.011
lin7a	lin-7 homolog A (C. elegans)	0.011
kcmf1	potassium channel modulatory factor 1	0.011
cse1l	chromosome segregation 1-like (S. cerevisiae)	0.011
skiv2l2	superkiller viralicidic activity 2-like 2	0.011
si:ch211-35n24.1	si:ch211-35n24.1	0.011
spg21	spastic paraplegia 21 (H. sapiens)	0.011
snw1	SNW domain containing 1	0.011
kcnk5	potassium channel, subfamily K, member 5	0.011
clasp2	cytoplasmic linker associated protein 2	0.011
slc15a2	solute carrier family 15 (H+/peptide transporter), member 2	0.011
il4	interleukin 4	0.010
ptn	pleiotrophin	0.010
dda1	DET1 and DDB1 associated 1	0.010
gria1a	glutamate receptor, ionotropic, AMPA 1a	0.010
unc5b	unc-5 homolog B (C. elegans)	0.010
gria1b	glutamate receptor, ionotropic, AMPA 1b	0.010
mknk2b	MAP kinase-interacting serine/threonine kinase 2b	0.010
mettl16	methyltransferase like 16	0.010
tfip11	tuftelin interacting protein 11	0.010
pdss2	prenyl (decaprenyl) diphosphate synthase, subunit 2	0.010
irgq1	immunity-related GTPase family, q1	0.010
si:ch211-149p10.2	si:ch211-149p10.2	0.010
ifng1-1	interferon, gamma 1-1	0.010
clk4b	CDC-like kinase 4b	0.010
agxta	alanine-glyoxylate aminotransferase a	0.010
h3f3b.1	H3 histone, family 3B.1	0.010
rgs18	regulator of G-protein signaling 18	0.010
amfr	autocrine motility factor receptor	0.010
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.010
isoc2	isochorismatase domain containing 2	0.010
mib2	mind bomb 2	0.010
atxn7l2b	ataxin 7-like 2b	0.010
msna	moesin a	0.010
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.010
nrl	neural retina leucine zipper	0.010
prkcbp1l	protein kinase C binding protein 1, like	0.010
adam8a	a disintegrin and metalloproteinase domain 8a	0.010
rapsn	receptor-associated protein of the synapse, 43kD	0.010
chic2	cysteine-rich hydrophobic domain 2	0.010
rbm18	RNA binding motif protein 18	0.010
cxxc1	CXXC finger 1 (PHD domain)	0.010
slc9a1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.010
zeb1	zinc finger E-box binding homeobox 1	0.010
si:ch211-57g18.1	si:ch211-57g18.1	0.010
ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.010
rbm22	RNA binding motif protein 22	0.010
vps39	vacuolar protein sorting 39 homolog (S. cerevisiae)	0.010
yeats4	YEATS domain containing 4	0.010
aftpha	aftiphilin a	0.010
usp28	ubiquitin specific peptidase 28	0.010
mapkapk2a	mitogen-activated protein kinase-activated protein kinase 2a	0.010
brms1la	breast cancer metastasis-suppressor 1-like a	0.010
csf3r	colony stimulating factor 3 receptor (granulocyte)	0.010
fbxw11b	F-box and WD-40 domain protein 11b	0.010	Fly
jak2b	Janus kinase 2b	0.010