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Danio rerio

0 genes annotated in zebrafish

colon cancer

DOID:219

A colorectal cancer that is located in the colon.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "colon cancer" (in gray)

Name	Description	Probability	Func Analog Organism
wls	wntless homolog (Drosophila)	0.360
smad5	MAD homolog 5 (Drosophila)	0.335
neo1	neogenin 1	0.272
gli2a	GLI-Kruppel family member GLI2a	0.228
cdh2	cadherin 2, neuronal	0.164
slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	0.140
fgfr4	fibroblast growth factor receptor 4	0.135
pbx4	pre-B-cell leukemia transcription factor 4	0.135
her9	hairy-related 9	0.124
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.117
bactin1	bactin1	0.116
sox11b	SRY-box containing gene 11b	0.106
gata1a	GATA binding protein 1a	0.102
dag1	dystroglycan 1	0.093
fzd7a	frizzled homolog 7a	0.083
znf503	zinc finger protein 503	0.080
pcna	proliferating cell nuclear antigen	0.073
meis1	myeloid ecotropic viral integration 1	0.064
celf1	cugbp, Elav-like family member 1	0.064
fzd7b	frizzled homolog 7b	0.060
cdkn1a	cyclin-dependent kinase inhibitor 1A	0.060
dusp6	dual specificity phosphatase 6	0.056
fgfr2	fibroblast growth factor receptor 2	0.056
lfng	lunatic fringe homolog	0.055
ccng1	cyclin G1	0.052
znf703	zinc finger protein 703	0.052
tp53	tumor protein p53	0.052	Human
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.047
mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.046
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.045
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.043
ccnd1	cyclin D1	0.042	Human
cdc20	cell division cycle 20 homolog	0.039
ccnb2	cyclin B2	0.039
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.038
ef1a	elongation factor 1-alpha	0.038
wnt11r	wingless-type MMTV integration site family, member 11, related	0.037
pcdh19	protocadherin 19	0.036
her6	hairy-related 6	0.035
ccnb1	cyclin B1	0.035
nrarpa	notch-regulated ankyrin repeat protein a	0.035
hoxb8a	homeo box B8a	0.035
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.034
met	met proto-oncogene (hepatocyte growth factor receptor)	0.034
lamc1	laminin, gamma 1	0.033
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.033
lef1	lymphocyte enhancer binding factor 1	0.032
krt4	keratin 4	0.032
ccna2	cyclin A2	0.031
gclm	glutamate-cysteine ligase, modifier subunit	0.029
elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.028
sfrp1a	secreted frizzled-related protein 1a	0.028
notch3	notch homolog 3	0.027
mmp9	matrix metalloproteinase 9	0.027
cahz	carbonic anhydrase	0.027
sox21a	SRY-box containing gene 21a	0.027
ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.026
eaf2	ELL associated factor 2	0.026
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.026
nr2f5	nuclear receptor subfamily 2, group F, member 5	0.026
cdc25	cell division cycle 25 homolog	0.025
hmga1a	high mobility group AT-hook 1a	0.025
lamb1a	laminin, beta 1a	0.025
ahctf1	AT hook containing transcription factor 1	0.024
pcdh18a	protocadherin 18a	0.024
dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.023
pdgfaa	platelet-derived growth factor alpha a	0.023
mcl1a	myeloid cell leukemia sequence 1a	0.023
slc4a1a	solute carrier family 4, anion exchanger, member 1a	0.023
axin2	axin 2 (conductin, axil)	0.023	Human
chd7	chromodomain helicase DNA binding protein 7	0.022
trim71	tripartite motif-containing 71	0.021
tcf12	transcription factor 12	0.021
tgif1	TGFB-induced factor homeobox 1	0.021
zgc:162630	zgc:162630	0.021
hoxa4a	homeo box A4a	0.020
pea3	ETS-domain transcription factor pea3	0.020
dnmt7	DNA (cytosine-5-)-methyltransferase 7	0.020
prmt1	protein arginine methyltransferase 1	0.020
plk1	polo-like kinase 1 (Drosophila)	0.019
hoxb3a	homeo box B3a	0.019
yap1	Yes-associated protein 1	0.019
psen1	presenilin 1	0.019
slc20a1b	solute carrier family 20, member 1b	0.019
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.019
pdcd2	programmed cell death 2	0.019
irx3a	iroquois homeobox protein 3a	0.018
zgc:55671	zgc:55671	0.018
urod	uroporphyrinogen decarboxylase	0.018
atp6v0ca	ATPase, H+ transporting, lysosomal, V0 subunit c, a	0.018
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.017
tfr1a	transferrin receptor 1a	0.017
mych	myelocytomatosis oncogene homolog	0.017
max	myc-associated factor X	0.017
plod1a	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a	0.016
tmpoa	thymopoietin a	0.016
zgc:101724	zgc:101724	0.016
st8sia6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	0.016
puf60a	poly-U binding splicing factor a	0.016
gfer	growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)	0.016
fgfrl1a	fibroblast growth factor receptor-like 1a	0.016
mtdha	metadherin a	0.016
st8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.016
ryk	receptor-like tyrosine kinase	0.016
ctnnb1	catenin (cadherin-associated protein), beta 1	0.015	Human
zgc:110687	zgc:110687	0.015
nr2f1a	nuclear receptor subfamily 2, group F, member 1a	0.015
k23	k23 gene	0.015
cx43.4	connexin 43.4	0.015
mapk14a	mitogen-activated protein kinase 14a	0.015
pdlim4	PDZ and LIM domain 4	0.015
myod1	myogenic differentiation 1	0.014
lmo4a	LIM domain only 4a	0.014
khdrbs1a	KH domain containing, RNA binding, signal transduction associated 1a	0.014
stil	TAL1 (SCL) interrupting locus	0.014
acsl4a	acyl-CoA synthetase long-chain family member 4a	0.014
ctsl1a	cathepsin L, 1 a	0.014
rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.014
shha	sonic hedgehog a	0.014
ctsd	cathepsin D	0.014
hoxb2a	homeo box B2a	0.014
zeb1	zinc finger E-box binding homeobox 1	0.014
gli3	GLI-Kruppel family member GLI3	0.014
melk	maternal embryonic leucine zipper kinase	0.013
thoc4	THO complex 4	0.013
kif23	kinesin family member 23	0.013
baxa	bcl2-associated X protein, a	0.013	Human
hhip	hedgehog interacting protein	0.013
snai1a	snail homolog 1a (Drosophila)	0.013
nid2a	nidogen 2a (osteonidogen)	0.013
slc11a2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	0.013
tm9sf4	transmembrane 9 superfamily protein member 4	0.013
npc1	Niemann-Pick disease, type C1	0.013
tjp1	tight junction protein 1 (zona occludens 1)	0.013
zgc:64114	zgc:64114	0.013
pabpc1a	poly A binding protein, cytoplasmic 1 a	0.013
jag2	jagged 2	0.012
fancd2	Fanconi anemia, complementation group D2	0.012
sox11a	SRY-box containing gene 11a	0.012
diexf	digestive organ expansion factor homolog	0.012
ube2v2	ubiquitin-conjugating enzyme E2 variant 2	0.012
dhfr	dihydrofolate reductase	0.012
grna	granulin a	0.012
nras	neuroblastoma RAS viral (v-ras) oncogene homolog	0.012
bms1l	BMS1-like, ribosome assembly protein (yeast)	0.012
id2a	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a	0.012
scube2	signal peptide, CUB domain, EGF-like 2	0.012
trim33	tripartite motif-containing 33	0.012
sdcbp	syndecan binding protein (syntenin)	0.011
zbtb16a	zinc finger and BTB domain containing 16a	0.011
marcksb	myristoylated alanine rich protein kinase C substrate b	0.011
egfl6	EGF-like-domain, multiple 6	0.011
tal1	T-cell acute lymphocytic leukemia 1	0.011
ruvbl2	RuvB-like 2 (E. coli)	0.011
eif4a1a	eukaryotic translation initiation factor 4A, isoform 1A	0.011
crabp2b	cellular retinoic acid binding protein 2, b	0.011
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.011
smc4	structural maintenance of chromosomes 4	0.011
gnb2l1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	0.011
hs6st2	heparan sulfate 6-O-sulfotransferase 2	0.011
atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.011
odc1	ornithine decarboxylase 1	0.011	Human
rrm2b	ribonucleotide reductase M2 b	0.011
myca	myelocytomatosis oncogene a	0.011
epha2	eph receptor A2	0.011
actn1	actinin, alpha 1	0.011
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.011
tlr3	toll-like receptor 3	0.011
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.011
irx5a	iroquois homeobox protein 5a	0.011
fgfr1b	fibroblast growth factor receptor 1b	0.011
sulf1	sulfatase 1	0.011
erf	Ets2 repressor factor	0.011
bcl2	B-cell leukemia/lymphoma 2	0.011
napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha	0.010
si:dkey-261h17.1	si:dkey-261h17.1	0.010
dld	deltaD	0.010
foxa3	forkhead box A3	0.010
rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.010
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.010
cx30.3	connexin 30.3	0.010
ntn1a	netrin 1a	0.010
rbl1	retinoblastoma-like 1 (p107)	0.010
ttnb	titin b	0.010