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Process View

Danio rerio

12 genes annotated in zebrafish

thyroid gland development

The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.

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In addition to gene-name show these genes:

Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "thyroid gland development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "thyroid gland development" (in gray)

Name	Description	Probability	Func Analog Organism
pax2a	paired box gene 2a	0.996
tbx1	T-box 1	0.897	Mouse
tal1	T-cell acute lymphocytic leukemia 1	0.879
foxa1	forkhead box A1	0.679
hoxa2b	homeo box A2b	0.666
atoh1a	atonal homolog 1a	0.656	Zebrafish
dla	deltaA	0.613	Zebrafish
gata4	GATA-binding protein 4	0.590	Zebrafish
nkx2.2a	NK2 transcription factor related 2a	0.575	Zebrafish
runx1	runt-related transcription factor 1	0.574
hand2	heart and neural crest derivatives expressed transcript 2	0.548
ncs1a	neuronal calcium sensor 1a	0.498
pax8	paired box gene 8	0.462	Human Zebrafish Mouse
erg	v-ets erythroblastosis virus E26 oncogene like (avian)	0.435
notch1a	notch homolog 1a	0.386
pitx2	paired-like homeodomain transcription factor 2	0.380
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.356
hhex	hematopoietically expressed homeobox	0.316
foxi1	forkhead box I1	0.299
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.285
foxa2	forkhead box A2	0.268
gata2a	GATA-binding protein 2a	0.267	Zebrafish
barhl2	BarH-like 2	0.263
fgf8a	fibroblast growth factor 8 a	0.251
fras1	Fraser syndrome 1	0.231
nkx2.5	NK2 transcription factor related 5	0.218	Zebrafish
nkx2.1a	NK2 homeobox 1a	0.201
nkx2.2b	NK2 transcription factor related 2b	0.198	Zebrafish
sox9a	SRY-box containing gene 9a	0.197
neurod4	neurogenic differentiation 4	0.195	Zebrafish
bcl2l1	bcl2-like 1	0.194
nkx3.2	NK3 homeobox 2	0.193
hoxb4a	homeo box B4a	0.189
dmrt2a	doublesex and mab-3 related transcription factor 2a	0.182
dlb	deltaB	0.176	Zebrafish
jag1b	jagged 1b	0.175
jag2	jagged 2	0.175	Zebrafish
fgf3	fibroblast growth factor 3	0.165
slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.162
pitx3	paired-like homeodomain transcription factor 3	0.162
mcl1a	myeloid cell leukemia sequence 1a	0.156	Zebrafish
eng2b	engrailed 2b	0.150
gata5	GATA-binding protein 5	0.149
prox1	prospero-related homeobox gene 1	0.149
dlx3b	distal-less homeobox gene 3b	0.147
tbx24	T-box 24	0.140
dlc	deltaC	0.136	Zebrafish
isl1	islet1	0.132
nppa	natriuretic peptide precursor A	0.132
sox9b	SRY-box containing gene 9b	0.124
gata1a	GATA binding protein 1a	0.118	Zebrafish
dbx1b	developing brain homeobox 1b	0.118
evx1	even-skipped homeobox 1	0.118
mib	mind bomb	0.116
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.101
mcl1b	myeloid cell leukemia sequence 1b	0.100	Zebrafish
tie2	endothelium-specific receptor tyrosine kinase 2	0.095
hoxa3a	homeo box A3a	0.095	Mouse
gdf6a	growth differentiation factor 6a	0.094
baxa	bcl2-associated X protein, a	0.093	Zebrafish
nkx2.3	NK2 transcription factor related 3	0.092	Zebrafish
mitfa	microphthalmia-associated transcription factor a	0.091
runx3	runt-related transcription factor 3	0.088
tbx20	T-box 20	0.087
tgfb3	transforming growth factor, beta 3	0.084
dld	deltaD	0.083	Zebrafish
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.080
cdh5	cadherin 5	0.078
ptf1a	pancreas specific transcription factor, 1a	0.075	Zebrafish
her1	hairy-related 1	0.072
flt1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.072	Zebrafish
rnasel1	ribonuclease like 1	0.071
hbbe3	hemoglobin beta embryonic-3	0.070
bmp4	bone morphogenetic protein 4	0.069
dll4	delta-like 4 (Drosophila)	0.063	Zebrafish
lhx1a	LIM homeobox 1a	0.059
tbx2b	T-box 2b	0.059
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.058
gli1	GLI-Kruppel family member 1	0.057
cmyb	transcription factor cmyb	0.055
myf5	myogenic factor 5	0.054
si:ch211-235f6.2	si:ch211-235f6.2	0.053
lhx1b	LIM homeobox 1b	0.052
gpr126	G protein-coupled receptor 126	0.049
gbx2	gastrulation brain homeo box 2	0.048
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.047
bbc3	BCL2 binding component 3	0.046
olig3	oligodendrocyte transcription factor 3	0.045
kdr	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.043	Zebrafish
sox1a	SRY-box containing gene 1a	0.042
myod1	myogenic differentiation 1	0.042
bmp2b	bone morphogenetic protein 2b	0.041
foxd3	forkhead box D3	0.041
mcamb	melanoma cell adhesion molecule b	0.040
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.038
aplnrb	apelin receptor b	0.037
hmx4	H6 family homeobox 4	0.036
tp63	tumor protein p63	0.036
sox7	SRY-box containing gene 7	0.035
hoxd3a	homeo box D3a	0.035	Mouse
eya1	eyes absent homolog 1	0.035
notch3	notch homolog 3	0.035
lmo2	LIM domain only 2 (rhombotin-like 1)	0.034
thraa	thyroid hormone receptor alpha a	0.034	Mouse
gata6	GATA-binding protein 6	0.034
atoh1b	atonal homolog 1b	0.032	Zebrafish
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.032
mespb	mesoderm posterior b	0.031
egr1	early growth response 1	0.031
foxj1a	forkhead box J1a	0.030
six4b	sine oculis homeobox homolog 4b	0.030
lama5	laminin, alpha 5	0.030
fgfrl1b	fibroblast growth factor receptor-like 1b	0.028
hoxb6a	homeo box B6a	0.028
pou4f1	POU domain, class 4, transcription factor 1	0.026
edn1	endothelin 1	0.026
nrarpb	notch-regulated ankyrin repeat protein b	0.026
hoxd4a	homeo box D4a	0.026
fli1a	friend leukemia integration 1a	0.025
igfbp3	insulin-like growth factor binding protein 3	0.025
bcl2	B-cell leukemia/lymphoma 2	0.025	Zebrafish
znfl2a	zinc finger-like gene 2a	0.024
hoxb3a	homeo box B3a	0.023	Mouse
limk1	LIM domain kinase 1	0.023
hoxb5b	homeo box B5b	0.023
nphs2	nephrosis 2, idiopathic, steroid-resistant (podocin)	0.023
alcama	activated leukocyte cell adhesion molecule a	0.023
dlx4b	distal-less homeobox gene 4b	0.023
meis3	myeloid ecotropic viral integration site 3	0.023
osr1	odd-skipped related 1 (Drosophila)	0.022
tp53	tumor protein p53	0.022
sulf1	sulfatase 1	0.021
pdlim3a	PDZ and LIM domain 3a	0.021
pou1f1	POU domain, class 1, transcription factor 1	0.021
fn1	fibronectin 1	0.020
her5	hairy-related 5	0.020
vmhcl	ventricular myosin heavy chain-like	0.020
ptgs1	prostaglandin-endoperoxide synthase 1	0.019
cdx4	caudal type homeo box transcription factor 4	0.019
zgc:112355	zgc:112355	0.019
wu:fv91b12	wu:fv91b12	0.019
nkx2.1b	NK2 homeobox 1b	0.019	Human Zebrafish Mouse
vwf	von Willebrand factor	0.018
hoxb6b	homeo box B6b	0.018
rxrga	retinoid x receptor, gamma a	0.018
tbx5a	T-box 5a	0.017
pcdh10b	protocadherin 10b	0.017
eng1a	engrailed 1a	0.016
pdx1	pancreatic and duodenal homeobox 1	0.016
pax5	paired box gene 5	0.016	Zebrafish
six4a	sine oculis homeobox homolog 4a	0.015
flt4	fms-related tyrosine kinase 4	0.015	Zebrafish
traf4a	tnf receptor-associated factor 4a	0.015
pax6b	paired box gene 6b	0.015
dlx4a	distal-less homeobox gene 4a	0.015
egr2a	early growth response 2a	0.015
fech	ferrochelatase	0.015
bida	BH3 interacting domain death agonist	0.015
wnt4b	wingless-type MMTV integration site family, member 4b	0.014
hoxb2a	homeo box B2a	0.014
six2a	sine oculis-related homeobox 2a	0.014
zgc:110784	zgc:110784	0.013
irx4b	iroquois homeobox protein 4b	0.013
lhx5	LIM homeobox 5	0.013
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.013
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.013
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.013
tp73	tumor protein p73	0.013
zgc:162630	zgc:162630	0.013
spaw	southpaw	0.013
nkx2.9	NK2 transcription factor related, locus 9 (Drosophila)	0.013	Zebrafish
stc1l	stanniocalcin 1, like	0.013
hnf1ba	HNF1 homeobox Ba	0.013
hoxb1b	homeo box B1b	0.012
otomp	otolith matrix protein	0.012
barx1	BarH-like homeobox 1	0.012
met	met proto-oncogene (hepatocyte growth factor receptor)	0.012
aldoca	aldolase C, fructose-bisphosphate, a	0.012
cyp1a	cytochrome P450, family 1, subfamily A	0.012
rhcgb	Rhesus blood group, C glycoprotein b	0.012
efnb2a	ephrin B2a	0.012
hoxa9a	homeo box A9a	0.012
gata3	GATA-binding protein 3	0.012	Zebrafish
bad	BCL2-antagonist of cell death	0.012
sesn1	sestrin 1	0.012
sox10	SRY-box containing gene 10	0.012
zgc:64114	zgc:64114	0.011
hoxb8a	homeo box B8a	0.010
klf4	Kruppel-like factor 4	0.010
aplnra	apelin receptor a	0.010
nkx2.7	NK2 transcription factor related 7	0.010	Zebrafish