IMP

Process View

Danio rerio

2 genes annotated in zebrafish

Multi-species View

establishment of epithelial cell polarity

GO:0090162

The specification and formation of anisotropic intracellular organization of an epithelial cell.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in zebrafish Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "establishment of epithelial cell polarity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "establishment of epithelial cell polarity" (in gray)

Name	Description	Probability	Func Analog Organism
prkci	protein kinase C, iota	0.544
crb2a	crumbs homolog 2a	0.537
epb41l5	erythrocyte membrane protein band 4.1 like 5	0.450	Fly
lamb1a	laminin, beta 1a	0.318
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.224
mib	mind bomb	0.208
ctbp2l	C-terminal binding protein 2, like	0.166
nyx	nyctalopin	0.166
guca1c	guanylate cyclase activator 1C	0.158
dspa	desmoplakin a	0.140
alcama	activated leukocyte cell adhesion molecule a	0.138
col2a1a	collagen type II, alpha-1a	0.120
lama1	laminin, alpha 1	0.116
jup	junction plakoglobin	0.116
waca	WW domain containing adaptor with coiled-coil a	0.113
llgl2	lethal giant larvae homolog 2 (Drosophila)	0.112	Fly
dvl3	dishevelled, dsh homolog 3 (Drosophila)	0.107	Fly
ptpra	protein tyrosine phosphatase, receptor type, A	0.107
celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 and cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.103
cdh1	cadherin 1, epithelial	0.101	Zebrafish
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.095
tpp1	tripeptidyl peptidase I	0.091
nrp1a	neuropilin 1a	0.088
axin1	axin 1	0.083
cyfip2	cytoplasmic FMR1 interacting protein 2	0.077
clrn1	clarin 1	0.074
snai1a	snail homolog 1a (Drosophila)	0.074
cdh2	cadherin 2, neuronal	0.070
sypb	synaptophysin b	0.069
lsr	lipolysis stimulated lipoprotein receptor	0.069
plp1b	proteolipid protein 1b	0.068
ctnnb1	catenin (cadherin-associated protein), beta 1	0.067
tnnt2a	troponin T2a, cardiac	0.067
osr2	odd-skipped related 2 (Drosophila)	0.058
dag1	dystroglycan 1	0.057
synj1	synaptojanin 1	0.056
zgc:100829	zgc:100829	0.055
pax2a	paired box gene 2a	0.052
ptpn11a	protein tyrosine phosphatase, non-receptor type 11, a	0.051
ilk	integrin linked kinase	0.051
gab1	GRB2-associated binding protein 1	0.050
krt8	keratin 8	0.049
twist1a	twist1a	0.049
ftr82	finTRIM family, member 82	0.047
flr	fleer	0.046
lims1	LIM and senescent cell antigen-like domains 1	0.046
dctn1a	dynactin 1a	0.045
nrp2b	neuropilin 2b	0.045
p2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.045
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.040
sdprb	serum deprivation response b	0.039
st14a	suppression of tumorigenicity 14 (colon carcinoma) a	0.038
waslb	Wiskott-Aldrich syndrome-like b	0.038
dsg2	desmoglein 2	0.038
prkcz	protein kinase C, zeta	0.037
tert	telomerase reverse transcriptase	0.037
top2b	topoisomerase (DNA) II beta	0.037
ctnna	catenin (cadherin-associated protein), alpha	0.036
fam3c	family with sequence similarity 3, member C	0.036
zgc:56010	zgc:56010	0.036
cplx4a	complexin 4a	0.035
opa3	optic atrophy 3	0.035
mapkapk2a	mitogen-activated protein kinase-activated protein kinase 2a	0.033
atp1a1a.4	ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide	0.032
epcam	epithelial cell adhesion molecule	0.032
znf395a	zinc finger protein 395a	0.032
pbx4	pre-B-cell leukemia transcription factor 4	0.032
cldnc	claudin c	0.032
nrp1b	neuropilin 1b	0.032
f11r	F11 receptor	0.031
cx52.9	connexin 52.9	0.031
pou4f1	POU domain, class 4, transcription factor 1	0.030
lmo2	LIM domain only 2 (rhombotin-like 1)	0.030
chrnd	cholinergic receptor, nicotinic, delta polypeptide	0.029
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.029
zgc:101523	zgc:101523	0.029
ythdf1	YTH domain family, member 1	0.028
zgc:66100	zgc:66100	0.028
tgfb3	transforming growth factor, beta 3	0.028
emp2	epithelial membrane protein 2	0.027
slc43a1a	solute carrier family 43, member 1a	0.027
lamc1	laminin, gamma 1	0.026
zgc:162213	zgc:162213	0.026
ift88	intraflagellar transport 88 homolog	0.026
flncb	filamin C, gamma b (actin binding protein 280)	0.026
ndrg1	N-myc downstream regulated gene 1	0.026
ppap2c	phosphatidic acid phosphatase type 2C	0.026
pvrl1a	poliovirus receptor-related 1a	0.026
epha2	eph receptor A2	0.025
spint1a	serine peptidase inhibitor, Kunitz type 1 a	0.025
zgc:101598	zgc:101598	0.025
pcdh2ac	protocadherin 2 alpha c	0.025
wt1b	wilms tumor 1b	0.025
vcana	versican a	0.024
mef2a	myocyte enhancer factor 2a	0.024
olfm1b	olfactomedin 1b	0.024
krml2.2	Kreisler (mouse) maf-related leucine zipper homolog 2.2	0.024
cenph	centromere protein H	0.024
cntn1b	contactin 1b	0.023
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.023
npc1	Niemann-Pick disease, type C1	0.023
anxa11a	annexin A11a	0.023
notch1a	notch homolog 1a	0.023
src	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.023
myo6b	myosin VIb	0.023
ptbp1b	polypyrimidine tract binding protein 1b	0.023
cdh6	cadherin 6	0.022
entpd3	ectonucleoside triphosphate diphosphohydrolase 3	0.022
wu:fc76b04	wu:fc76b04	0.022
ckap5	cytoskeleton associated protein 5	0.021
hnf1bb	HNF1 homeobox Bb	0.021
pdlim1	PDZ and LIM domain 1 (elfin)	0.021
ggnbp2	gametogenetin binding protein 2	0.021
dvl2	dishevelled, dsh homolog 2 (Drosophila)	0.021	Fly
cry3	cryptochrome 3	0.021
gtpbp1	GTP binding protein 1	0.020
lrp2	low density lipoprotein-related protein 2	0.020
pak2a	p21 (CDKN1A)-activated kinase 2a	0.020
zgc:123010	zgc:123010	0.020
dennd5b	DENN/MADD domain containing 5B	0.020
plk3	polo-like kinase 3 (Drosophila)	0.019
flii	flightless I homolog (Drosophila)	0.019
mpz	myelin protein zero	0.019
kif17	kinesin family member 17	0.019
bmp7b	bone morphogenetic protein 7b	0.019
anxa2b	annexin A2b	0.019
itga5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.018
mitfa	microphthalmia-associated transcription factor a	0.018
plcg1	phospholipase C, gamma 1	0.018
tgif1	TGFB-induced factor homeobox 1	0.018
sdcbp	syndecan binding protein (syntenin)	0.018
hgfa	hepatocyte growth factor a	0.018
wu:fb54a03	wu:fb54a03	0.017
cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.017
phox2b	paired-like homeobox 2b	0.017
dnmt8	DNA (cytosine-5-)-methyltransferase 8	0.017
atp6v1ba	ATPase, H+ transporting, lysosomal, V1 subunit B, member a	0.017
gmds	GDP-mannose 4,6-dehydratase	0.017
trim71	tripartite motif-containing 71	0.017
ptf1a	pancreas specific transcription factor, 1a	0.017
robo2	roundabout homolog 2	0.017
si:ch211-215l11.5	si:ch211-215l11.5	0.016
rb1	retinoblastoma 1	0.016
plekha1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.016
smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.016
sb:cb1058	sb:cb1058	0.016
tfa	transferrin-a	0.016
slc20a1a	solute carrier family 20, member 1a	0.015
nuak2	NUAK family, SNF1-like kinase, 2	0.015
cdh4	cadherin 4, retinal	0.015	Zebrafish
stil	TAL1 (SCL) interrupting locus	0.015
slit3	slit (Drosophila) homolog 3	0.015
srp54	signal recognition particle 54	0.015
chst10	carbohydrate sulfotransferase 10	0.015
cd9b	CD9 antigen, b	0.015
sp4	sp4 transcription factor	0.015
slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.015
cxadr	coxsackie virus and adenovirus receptor	0.015
rras	related RAS viral (r-ras) oncogene homolog	0.015
stk35l	serine/threonine kinase 35, like	0.015
celf1	cugbp, Elav-like family member 1	0.014
wdr45l	wdr45 like	0.014
pou4f3	POU domain, class 4, transcription factor 3	0.014
slc38a3	solute carrier family 38, member 3	0.014
rmnd5b	required for meiotic nuclear division 5 homolog B (S. cerevisiae)	0.014
cdk8	cyclin-dependent kinase 8	0.014
erf	Ets2 repressor factor	0.014
cldn7b	claudin 7b	0.014
shroom4	shroom family member 4	0.014
si:dkey-162b3.1	si:dkey-162b3.1	0.014
eya1	eyes absent homolog 1	0.014
rela	v-rel reticuloendotheliosis viral oncogene homolog A	0.014
LOC561183	tyrosine-protein kinase transmembrane receptor ROR2-like	0.014
slc15a2	solute carrier family 15 (H+/peptide transporter), member 2	0.014
si:ch211-254d18.3	si:ch211-254d18.3	0.014
si:dkey-261h17.1	si:dkey-261h17.1	0.014
grma	glutamate receptor, metabotropic a	0.013
cstf3	cleavage stimulation factor, 3' pre-RNA, subunit 3	0.013
psap	prosaposin	0.013
scn1bb	sodium channel, voltage-gated, type I, beta b	0.013
mapk4	mitogen-activated protein kinase 4	0.013
grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.013
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.013
aktip	akt interacting protein	0.013
ttnb	titin b	0.013
esrp2	epithelial splicing regulatory protein 2	0.013
tmsb	thymosin, beta	0.013
rnf2	ring finger protein 2	0.013
fabp2	fatty acid binding protein 2, intestinal	0.013
pxn	paxillin	0.013
hif1al	hypoxia-inducible factor 1, alpha subunit, like	0.013
ccdc6b	coiled-coil domain containing 6b	0.013
slit2	slit (Drosophila) homolog 2	0.013
serinc2	serine incorporator 2	0.013
pard3	par-3 partitioning defective 3 homolog (C. elegans)	0.013	Rat
ift57	intraflagellar transport protein 57	0.013
zgc:152830	zgc:152830	0.013
wu:fc67d01	wu:fc67d01	0.013
mgrn1a	mahogunin, ring finger 1a	0.013
mtdha	metadherin a	0.013
anxa5b	annexin A5b	0.013
ap1b1	adaptor-related protein complex 1, beta 1 subunit	0.013
zgc:65861	zgc:65861	0.013
sept6	septin 6	0.013
cntn1a	contactin 1a	0.013
gatad2a	GATA zinc finger domain containing 2A	0.013
grb10a	growth factor receptor-bound protein 10a	0.012
rbp4	retinol binding protein 4, plasma	0.012
atg13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.012
p2rx3b	purinergic receptor P2X, ligand-gated ion channel, 3b	0.012
dlg4	discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila)	0.012
lztfl1	leucine zipper transcription factor-like 1	0.012
metrnl	meteorin, glial cell differentiation regulator-like	0.012
sept8a	septin 8a	0.012
crb2b	crumbs homolog 2b	0.012
glcci1	glucocorticoid induced transcript 1	0.012
ell2	elongation factor, RNA polymerase II, 2	0.012
wipi2	WD repeat domain, phosphoinositide interacting 2	0.012
celsr3	cadherin, EGF LAG seven-pass G-type receptor 3	0.012
faf2	Fas associated factor family member 2	0.012
ulk1b	unc-51-like kinase 1b (C. elegans)	0.012
pomgnt1	protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase	0.012
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.012
wu:fi36c02	wu:fi36c02	0.012
trpa1a	transient receptor potential cation channel, subfamily A, member 1a	0.012
srrm1	serine/arginine repetitive matrix 1	0.012
zgc:92789	zgc:92789	0.012
wars	tryptophanyl-tRNA synthetase	0.012
ube2e3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)	0.012
im:7145024	im:7145024	0.012
foxk1	forkhead box K1	0.012
tsc22d2	TSC22 domain family 2 and TSC22 domain family, member 2	0.011
syncripl	synaptotagmin binding, cytoplasmic RNA interacting protein, like	0.011
pea3	ETS-domain transcription factor pea3	0.011
si:ch211-261f7.2	si:ch211-261f7.2	0.011
abca1b	ATP-binding cassette, sub-family A (ABC1), member 1B	0.011
LOC567547	5,10-methylenetetrahydrofolate reductase (NADPH)-like	0.011
krt18	keratin 18	0.011
zgc:114097	zgc:114097	0.011
rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.011
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.011
nrf1	nuclear respiratory factor 1	0.011
ccnt2a	cyclin T2a	0.011
kif7	kinesin family member 7	0.011
cyp3c1l2	cytochrome P450, family 3, subfamily c, polypeptide 1 like, 2	0.011
bhmt	betaine-homocysteine methyltransferase	0.011
ass1	argininosuccinate synthetase 1	0.011
suz12b	suppressor of zeste 12 homolog (Drosophila) b	0.011
taf8	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.011
ptprfb	protein tyrosine phosphatase, receptor type, f, b	0.011
ehd1	EH-domain containing 1	0.011
ttc21b	tetratricopeptide repeat domain 21B	0.011
morn4	MORN repeat containing 4	0.011
si:ch211-166a6.5	si:ch211-166a6.5	0.011
ripk4	receptor-interacting serine-threonine kinase 4	0.011
ef1	ETS-related factor1	0.011
zgc:55573	zgc:55573	0.011
tpm4	tropomyosin 4	0.011
pck2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	0.011
celsr1a	cadherin EGF LAG seven-pass G-type receptor 1a	0.011
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.011
faf1	Fas associated factor 1	0.011
ret1	receptor tyrosine kinase	0.011
gnaia	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a	0.011
lsm12	LSM12 homolog (S. cerevisiae)	0.011
zgc:55557	zgc:55557	0.011
supt3h	suppressor of Ty 3 homolog (S. cerevisiae)	0.011
notch3	notch homolog 3	0.011
p4ha1b	prolyl 4-hydroxylase, alpha polypeptide I b	0.011
ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.011
slc4a2a	solute carrier family 4, anion exchanger, member 2a	0.011
ptrfb	polymerase I and transcript release factor b	0.011
tnfaip8	tumor necrosis factor, alpha-induced protein 8	0.010
im:7153078	im:7153078	0.010
cubn	cubilin (intrinsic factor-cobalamin receptor)	0.010
plcd1b	phospholipase C, delta 1b	0.010
zgc:56676	zgc:56676	0.010
slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.010
fzd7b	frizzled homolog 7b	0.010
zgc:55886	zgc:55886	0.010
ptprf	protein tyrosine phosphatase, receptor type, F	0.010
ubtf	upstream binding transcription factor, RNA polymerase I	0.010
hug	HuG	0.010
tbc1d16	TBC1 domain family, member 16	0.010
zgc:153997	zgc:153997	0.010
ntrk3b	neurotrophic tyrosine kinase, receptor, type 3b	0.010
gc3	guanylyl cyclase 3	0.010
psip1	PC4 and SFRS1 interacting protein 1	0.010
atg9a	ATG9 autophagy related 9 homolog A (S. cerevisiae)	0.010
hlxb9la	homeo box HB9 like a	0.010
mylka	myosin, light chain kinase a	0.010
bbs1	Bardet-Biedl syndrome 1	0.010
slc25a32b	solute carrier family 25, member 32b	0.010
slc25a1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	0.010
foxf1	forkhead box F1	0.010
zgc:86598	zgc:86598	0.010
pdxdc1	pyridoxal-dependent decarboxylase domain containing 1	0.010
gbp	glycogen synthase kinase binding protein	0.010
spns1	spinster homolog 1 (Drosophila)	0.010
jph2	junctophilin 2	0.010
trpa1b	transient receptor potential cation channel, subfamily A, member 1b	0.010
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.010
zgc:55652	zgc:55652	0.010
csf3r	colony stimulating factor 3 receptor (granulocyte)	0.010
xrn2	5'-3' exoribonuclease 2	0.010
si:dkey-199f5.8	si:dkey-199f5.8	0.010
arhgef7a	Rho guanine nucleotide exchange factor (GEF) 7a	0.010