The network for 'receptor mediated endocytosis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

receptor mediated endocytosis

An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.

Homo sapiens
Name Description Probability Func Analog Organism
GRB2 growth factor receptor-bound protein 2 0.999
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.993
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.993
FYN FYN oncogene related to SRC, FGR, YES 0.968
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.963
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.930
SNX9 sorting nexin 9 0.928
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.895
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.803
SH3KBP1 SH3-domain kinase binding protein 1 0.772
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.727
TBP TATA box binding protein 0.691
C1QBP complement component 1, q subcomponent binding protein 0.685
TUFM Tu translation elongation factor, mitochondrial 0.661
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.623
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.601
HSPA4 heat shock 70kDa protein 4 0.564
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.555
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.549
MRPS28 mitochondrial ribosomal protein S28 0.545
RHOA ras homolog gene family, member A 0.536
DNM2 dynamin 2 0.527
ITSN1 intersectin 1 (SH3 domain protein) 0.514
ICT1 immature colon carcinoma transcript 1 0.502
HSPE1 heat shock 10kDa protein 1 (chaperonin 10) 0.485
PHB prohibitin 0.484
SMN1 survival of motor neuron 1, telomeric 0.479
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.463
SEC23B Sec23 homolog B (S. cerevisiae) 0.449
CAND1 cullin-associated and neddylation-dissociated 1 0.436
ESR1 estrogen receptor 1 0.426
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.425
QARS glutaminyl-tRNA synthetase 0.424
SSB Sjogren syndrome antigen B (autoantigen La) 0.419
EIF3F eukaryotic translation initiation factor 3, subunit F 0.404
FASLG Fas ligand (TNF superfamily, member 6) 0.403
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.393
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 0.391
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.386
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.382
EIF3A eukaryotic translation initiation factor 3, subunit A 0.381
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.374
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.369
FN1 fibronectin 1 0.361
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.357
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.351
RAB5A RAB5A, member RAS oncogene family 0.346
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.337
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.334
IK IK cytokine, down-regulator of HLA II 0.331
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.314
GSK3B glycogen synthase kinase 3 beta 0.312
RAD21 RAD21 homolog (S. pombe) 0.312
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.311
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 0.310
EFTUD2 elongation factor Tu GTP binding domain containing 2 0.307
STOML2 stomatin (EPB72)-like 2 0.299
NOL11 nucleolar protein 11 0.288
SH3GL2 SH3-domain GRB2-like 2 0.285
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 0.275
CAV1 caveolin 1, caveolae protein, 22kDa 0.273
EGFR epidermal growth factor receptor 0.272
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.269
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.269
NCK1 NCK adaptor protein 1 0.266
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 0.266
EZH2 enhancer of zeste homolog 2 (Drosophila) 0.263
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.262
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.257
ATXN1 ataxin 1 0.256
MRPL12 mitochondrial ribosomal protein L12 0.251
EPS15 epidermal growth factor receptor pathway substrate 15 0.251
TEK TEK tyrosine kinase, endothelial 0.250
POLR1C polymerase (RNA) I polypeptide C, 30kDa 0.249
CANX calnexin 0.249
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.248
PMPCA peptidase (mitochondrial processing) alpha 0.246
PWP1 PWP1 homolog (S. cerevisiae) 0.246
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.243
EIF3J eukaryotic translation initiation factor 3, subunit J 0.241
CCNB1 cyclin B1 0.240
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.239
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.234
TP53 tumor protein p53 0.232
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.227
KARS lysyl-tRNA synthetase 0.220
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.219
EIF3D eukaryotic translation initiation factor 3, subunit D 0.218
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.217
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.216
DKC1 dyskeratosis congenita 1, dyskerin 0.215
LCK lymphocyte-specific protein tyrosine kinase 0.214
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.212
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.210
EXOSC8 exosome component 8 0.210
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.205
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.204
POLA2 polymerase (DNA directed), alpha 2 (70kD subunit) 0.204
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 0.200
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.200
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
dao-5 Protein DAO-5 0.857
ZK1127.5 Protein ZK1127.5 0.852
hlh-2 Protein HLH-2 0.795
act-4 Protein ACT-4 0.789
C14C10.4 Protein C14C10.4 0.719
prp-8 Protein PRP-8 0.715
nhr-66 Protein NHR-66 0.693
vab-3 Protein VAB-3 0.682
par-6 Protein PAR-6 0.677
dnc-2 Protein DNC-2 0.675
eef-1A.1 Protein EEF-1A.1 0.669
wdr-46 Protein WDR-46 0.667
mpz-2 Protein MPZ-2 0.667
Y71G12B.8 Protein Y71G12B.8 0.662
K10D3.4 Protein K10D3.4 0.661
cul-1 Protein CUL-1 0.659
Y53C12B.1 Protein Y53C12B.1 0.641
K07C5.6 Protein K07C5.6 0.639
let-754 Protein LET-754 0.637
set-18 Protein SET-18 0.636
mrpl-4 Protein MRPL-4 0.635
klp-16 Protein KLP-16 0.635
F57B10.8 Protein F57B10.8 0.635
vps-37 Protein VPS-37 0.630
zyg-1 Protein ZYG-1 0.625
T20B12.3 Protein T20B12.3 0.624
Y48A6B.3 Protein Y48A6B.3 0.622
puf-7 Protein PUF-7 0.614
vha-9 Protein VHA-9 0.613
F35F11.1 Protein F35F11.1 0.608
F11A10.7 Protein F11A10.7 0.606
skp-1 Protein SKP-1 0.601
ubq-1 Protein UBQ-1 0.597
F09E5.3 Protein F09E5.3 0.593
mig-14 Protein MIG-14 0.592
lex-1 Protein LEX-1 0.584
F38A5.1 Protein F38A5.1 0.584
alx-1 Protein ALX-1 0.582
tag-184 Protein TAG-184 0.578
sex-1 Protein SEX-1 0.578
B0464.2 Protein B0464.2 0.575
col-125 Protein COL-125 0.570
rnp-5 Protein RNP-5 0.569
col-34 Protein COL-34 0.568
lsy-22 Protein LSY-22 0.568
npp-15 Protein NPP-15 0.563
T14G10.5 Protein T14G10.5 0.559
K12H4.3 Protein K12H4.3 0.556
sqt-3 Protein SQT-3 0.555
atp-5 Protein ATP-5 0.547
unc-60 Protein UNC-60 0.546
mrps-18C Protein MRPS-18C 0.546
icd-1 Protein ICD-1 0.538
coq-2 Protein COQ-2 0.534
inx-12 Protein INX-12 0.533
rpn-1 Protein RPN-1 0.531
rsp-1 Protein RSP-1 0.531
E02H1.6 Protein E02H1.6 0.530
snr-5 Protein SNR-5 0.529
cey-1 Protein CEY-1 0.528
Y45F10D.7 Protein Y45F10D.7 0.526
eif-3.C Protein EIF-3.C 0.524
fat-2 Protein FAT-2 0.521
CELE_T04A8.6 Protein T04A8.6 0.519
C18B2.5 Protein C18B2.5 0.518
ced-12 Protein CED-12 0.518
imb-3 Protein IMB-3 0.517
tut-1 Protein TUT-1 0.517
C27F2.8 Protein C27F2.8 0.517
inf-1 Protein INF-1 0.515
F36A2.9 Protein F36A2.9 0.514
spn-4 Protein SPN-4 0.514
cpf-2 Protein CPF-2 0.513
pat-3 Protein PAT-3 0.512
him-17 Protein HIM-17 0.510
tomm-40 Protein TOMM-40 0.507
eif-3.K Protein EIF-3.K 0.506
ttyh-1 Protein TTYH-1 0.505
col-107 Protein COL-107 0.505
hgrs-1 Protein HGRS-1 0.500
mat-3 Protein MAT-3 0.499
cye-1 Protein CYE-1 0.499
T11G6.8 Protein T11G6.8 0.498
xpo-2 Protein XPO-2 0.495
cmd-1 Protein CMD-1 0.493
sem-5 Protein SEM-5 0.489
col-154 Protein COL-154 0.489
cct-2 Protein CCT-2 0.488
pat-6 Protein PAT-6 0.487
prp-3 Protein PRP-3 0.487
stt-3 Protein STT-3 0.486
unc-53 Protein UNC-53 0.486
hcp-4 Protein HCP-4 0.485
CELE_F39H2.3 Protein F39H2.3 0.484
F09F7.3 Protein F09F7.3 0.483
CELE_F53C11.4 Protein F53C11.4 0.482
fipp-1 Protein FIPP-1 0.482
unc-54 Protein UNC-54 0.481
mrps-18B Protein MRPS-18B 0.480
npp-19 Protein NPP-19 0.479
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
csnk1a1 casein kinase 1, alpha 1 0.125
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.063
mib mind bomb 0.050
surf6 surfeit 6 0.046
nolc1 nucleolar and coiled-body phosphoprotein 1 0.045
ddx27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 0.044
lama5 laminin, alpha 5 0.033
tbx1 T-box 1 0.027
per3 period homolog 3 (Drosophila) 0.025
supt6h suppressor of Ty 6 homolog 0.025
im:7148292 im:7148292 0.024
cct3 chaperonin containing TCP1, subunit 3 (gamma) 0.024
clptm1 cleft lip and palate associated transmembrane protein 1 0.023
mki67ip mki67 (FHA domain) interacting nucleolar phosphoprotein (human) 0.023
atp1b3b ATPase, Na+/K+ transporting, beta 3b polypeptide 0.021
atp6v1h ATPase, H+ transporting, lysosomal, V1 subunit H 0.021
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.019
fbn2b fibrillin 2b 0.019
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.019
atp6v1ba ATPase, H+ transporting, lysosomal, V1 subunit B, member a 0.019
crip2 cysteine-rich protein 2 0.017
hspa8 heat shock protein 8 0.017
ran ras-related nuclear protein 0.016
pinx1 pin2/trf1-interacting protein 1 0.016
foxa2 forkhead box A2 0.015
notch1a notch homolog 1a 0.015
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.015
rpl7l1 ribosomal protein L7-like 1 0.014
med7 mediator complex subunit 7 0.014
lamc1 laminin, gamma 1 0.014
plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.014
wdr12 WD repeat domain 12 0.014
actn2 actinin, alpha 2 0.013
fbl fibrillarin 0.012
sec13 SEC13 homolog (S. cerevisiae) 0.012
smc1al structural maintenance of chromosomes 1A, like 0.012
birc5a baculoviral IAP repeat-containing 5a 0.012
cx39.9 connexin 39.9 0.012
rrp15 ribosomal RNA processing 15 homolog (S. cerevisiae) 0.012
txnrd1 thioredoxin reductase 1 0.012
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.012
aldocb aldolase C, fructose-bisphosphate, b 0.012
eif4a1a eukaryotic translation initiation factor 4A, isoform 1A 0.012
tnnt3b troponin T3b, skeletal, fast 0.012
fgfr1a fibroblast growth factor receptor 1a 0.012
eif3b eukaryotic translation initiation factor 3, subunit B 0.011
polr1b polymerase (RNA) I polypeptide B 0.011
acvr1l activin A receptor, type I like 0.011
actl6a actin-like 6A 0.011
ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.011
bop1 block of proliferation 1 0.011
sept7a septin 7a 0.011
pfdn5 prefoldin 5 0.011
notch2 notch homolog 2 0.011
zgc:73198 zgc:73198 0.011
mrpl45 mitochondrial ribosomal protein L45 0.011
calm3b calmodulin 3b (phosphorylase kinase, delta) 0.010
ngdn neuroguidin, EIF4E binding protein 0.010
rbmx RNA binding motif protein, X-linked 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Moe Moesin 0.271
arm armadillo 0.243
Gp150 CG5820 gene product from transcript CG5820-RA 0.222
mop myopic 0.150
put punt 0.149
Atpalpha Na pump alpha subunit 0.148
cpa capping protein alpha 0.141
tsr twinstar 0.133
Mer Merlin 0.130
ebi CG4063 gene product from transcript CG4063-RA 0.113
Arp14D Actin-related protein 14D 0.108
cpb capping protein beta 0.106
Chc Clathrin heavy chain 0.099
Xbp1 X box binding protein-1 0.097
srp serpent 0.095
dom domino 0.088
Rab5 Rab-protein 5 0.086
Arc-p34 CG10954 gene product from transcript CG10954-RA 0.084
CkIIalpha Casein kinase II alpha subunit 0.084
Rho1 CG8416 gene product from transcript CG8416-RB 0.083
mbc myoblast city 0.080
SF2 CG6987 gene product from transcript CG6987-RA 0.077
CG8258 CG8258 gene product from transcript CG8258-RA 0.076
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.075
zip zipper 0.074
Rab11 Rab-protein 11 0.071
scra scraps 0.070
lace CG4162 gene product from transcript CG4162-RA 0.063
Spt5 CG7626 gene product from transcript CG7626-RA 0.058
ik2 IkappaB kinase-like 2 0.053
Rala Ras-related protein 0.053
par-6 CG5884 gene product from transcript CG5884-RA 0.052
capt capulet 0.050
rhea CG6831 gene product from transcript CG6831-RA 0.049
Khc Kinesin heavy chain 0.049
LanA Laminin A 0.047
Cdc37 CG12019 gene product from transcript CG12019-RA 0.042
Actn alpha actinin 0.041
polo CG12306 gene product from transcript CG12306-RA 0.041
usp ultraspiracle 0.040
Nmt N-myristoyl transferase 0.040
osa CG7467 gene product from transcript CG7467-RD 0.039
Amph Amphiphysin 0.039
gish gilgamesh 0.038
klar klarsicht 0.037
Pvr PDGF- and VEGF-receptor related 0.037
numb CG3779 gene product from transcript CG3779-RB 0.037
Hem HEM-protein 0.035
sesB stress-sensitive B 0.035
beta-Spec beta Spectrin 0.034
cora coracle 0.034
CG10754 CG10754 gene product from transcript CG10754-RA 0.033
Rab7 Rab-protein 7 0.033
gammaCop gamma-coatomer protein 0.033
skpA CG16983 gene product from transcript CG16983-RD 0.033
G-oalpha47A G protein oalpha 47A 0.033
sti sticky 0.033
ecd ecdysoneless 0.032
Prp8 pre-mRNA processing factor 8 0.032
Acf1 ATP-dependent chromatin assembly factor large subunit 0.031
Aos1 CG12276 gene product from transcript CG12276-RA 0.031
Klp61F Kinesin-like protein at 61F 0.030
eIF3-S8 CG4954 gene product from transcript CG4954-RA 0.030
alphaTub67C alpha-Tubulin at 67C 0.030
T-cp1 Tcp1-like 0.029
Vha100-1 CG1709 gene product from transcript CG1709-RF 0.028
alpha-Adaptin CG4260 gene product from transcript CG4260-RA 0.028
Trxr-1 Thioredoxin reductase-1 0.027
pit pitchoune 0.027
Kap-alpha3 karyopherin alpha3 0.027
Tab2 TAK1-associated binding protein 2 0.027
mbo members only 0.027
EndoGI Endonuclease G inhibitor 0.027
Sra-1 specifically Rac1-associated protein 1 0.027
smo smoothened 0.027
Pp1-87B Protein phosphatase 1 at 87B 0.027
lwr lesswright 0.026
Tcp-1zeta T-cp1zeta 0.026
BRWD3 CG31132 gene product from transcript CG31132-RA 0.026
egl egalitarian 0.026
Gnf1 Germ line transcription factor 1 0.026
Rab6 Rab-protein 6 0.025
eff effete 0.024
eya eyes absent 0.024
Tak1 TGF-beta activated kinase 1 0.024
CG4699 CG4699 gene product from transcript CG4699-RJ 0.024
CG12301 CG12301 gene product from transcript CG12301-RA 0.024
cact cactus 0.024
Nrg Neuroglian 0.024
hiw highwire 0.024
CG13096 CG13096 gene product from transcript CG13096-RA 0.024
Tcp-1eta CG8351 gene product from transcript CG8351-RA 0.023
Bap Beta Adaptin 0.023
dsh dishevelled 0.023
CG32344 CG32344 gene product from transcript CG32344-RA 0.023
da daughterless 0.023
Dap160 Dynamin associated protein 160 0.023
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.023
SdhA Succinate dehydrogenase A 0.023
mys myospheroid 0.022
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.988
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.970
Ctnnb1 catenin (cadherin associated protein), beta 1 0.822
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.687
Apoe apolipoprotein E 0.645
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.616
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.592
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.504
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.488
Gsk3b glycogen synthase kinase 3 beta 0.455
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.452
Timeless timeless homolog (Drosophila) 0.411
Fgfr2 fibroblast growth factor receptor 2 0.383
App amyloid beta (A4) precursor protein 0.327
Pparg peroxisome proliferator activated receptor gamma 0.324
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.313
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.309
Cltc clathrin, heavy polypeptide (Hc) 0.286
Arid1a AT rich interactive domain 1A (SWI-like) 0.244
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.238
Capzb capping protein (actin filament) muscle Z-line, beta 0.221
Apc adenomatosis polyposis coli 0.213
Dab1 disabled homolog 1 (Drosophila) 0.211
Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.210
Hdac2 histone deacetylase 2 0.209
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.198
Bmp4 bone morphogenetic protein 4 0.195
Dmd dystrophin, muscular dystrophy 0.189
Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 0.182
Cct2 chaperonin containing Tcp1, subunit 2 (beta) 0.167
Mta1 metastasis associated 1 0.165
Cdk4 cyclin-dependent kinase 4 0.165
Eif2c2 eukaryotic translation initiation factor 2C, 2 0.164
Psen1 presenilin 1 0.163
Myh9 myosin, heavy polypeptide 9, non-muscle 0.160
Ccl2 chemokine (C-C motif) ligand 2 0.159
Dync1i2 dynein cytoplasmic 1 intermediate chain 2 0.157
Pola1 polymerase (DNA directed), alpha 1 0.154
Mybbp1a MYB binding protein (P160) 1a 0.149
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.148
Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 0.144
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.142
Klra9 killer cell lectin-like receptor subfamily A, member 9 0.141
Csf1 colony stimulating factor 1 (macrophage) 0.140
Ep400 E1A binding protein p400 0.138
Lrp2 low density lipoprotein receptor-related protein 2 0.136
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.135
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.134
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.133
Lepr leptin receptor 0.128
Hspa8 heat shock protein 8 0.128
Nos1 nitric oxide synthase 1, neuronal 0.128
Cfl1 cofilin 1, non-muscle 0.126
Col4a3 collagen, type IV, alpha 3 0.120
AF251705 cDNA sequence AF251705 0.118
Dlg4 discs, large homolog 4 (Drosophila) 0.115
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.115
Cct7 chaperonin containing Tcp1, subunit 7 (eta) 0.114
Arrb2 arrestin, beta 2 0.113
Pnpla2 patatin-like phospholipase domain containing 2 0.112
Ptrf polymerase I and transcript release factor 0.109
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.108
Notch1 Notch gene homolog 1 (Drosophila) 0.108
Eftud2 elongation factor Tu GTP binding domain containing 2 0.102
Src Rous sarcoma oncogene 0.100
Tyrobp TYRO protein tyrosine kinase binding protein 0.100
Gzma granzyme A 0.099
Notch2 Notch gene homolog 2 (Drosophila) 0.099
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 0.098
Actn4 actinin alpha 4 0.097
Tubb5 tubulin, beta 5 0.096
Cdc25a cell division cycle 25 homolog A (S. pombe) 0.096
Ccl12 chemokine (C-C motif) ligand 12 0.092
Cttn cortactin 0.091
Itga3 integrin alpha 3 0.091
Ager advanced glycosylation end product-specific receptor 0.091
Ncr1 natural cytotoxicity triggering receptor 1 0.091
Ap2a2 adaptor protein complex AP-2, alpha 2 subunit 0.091
Wdr1 WD repeat domain 1 0.090
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.088
Tcp1 t-complex protein 1 0.087
Prnp prion protein 0.087
Racgap1 Rac GTPase-activating protein 1 0.087
Sall4 sal-like 4 (Drosophila) 0.087
Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.086
Rock2 Rho-associated coiled-coil containing protein kinase 2 0.086
Npy2r neuropeptide Y receptor Y2 0.086
Itgax integrin alpha X 0.086
Csf1r colony stimulating factor 1 receptor 0.086
Arrb1 arrestin, beta 1 0.085
Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) 0.085
Phex phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) 0.085
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.084
Grb2 growth factor receptor bound protein 2 0.084
Amelx amelogenin X chromosome 0.084
C3ar1 complement component 3a receptor 1 0.083
Rrm1 ribonucleotide reductase M1 0.083
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.082
Ctnnd1 catenin (cadherin associated protein), delta 1 0.082
Hspd1 heat shock protein 1 (chaperonin) 0.082
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Gria2 glutamate receptor, ionotropic, AMPA 2 0.807
Dlg4 discs, large homolog 4 (Drosophila) 0.291
Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 0.253
Gja1 gap junction protein, alpha 1 0.246
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.150
Baiap2 BAI1-associated protein 2 0.134
Pkn2 protein kinase N2 0.119
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.102
Grip1 glutamate receptor interacting protein 1 0.099
Tmem101 transmembrane protein 101 0.096
Gria1 glutamate receptor, ionotropic, AMPA 1 0.095
LOC100362824 caveolin 2-like 0.093
Smad7 SMAD family member 7 0.093
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.092
Adam10 ADAM metallopeptidase domain 10 0.088
Ptk2b PTK2B protein tyrosine kinase 2 beta 0.082
Ap2b1 adaptor-related protein complex 2, beta 1 subunit 0.080
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.075
Csnk1g3 casein kinase 1, gamma 3 0.074
Dlg2 discs, large homolog 2 (Drosophila) 0.072
Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 0.072
Accn3 amiloride-sensitive cation channel 3 0.072
Tcf12 transcription factor 12 0.071
Trmt61a tRNA methyltransferase 61 homolog A (S. cerevisiae) 0.069
Rab6a RAB6A, member RAS oncogene family 0.067
Cast calpastatin 0.066
N5 DNA binding protein N5 0.064
Myo1d myosin ID 0.064
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.063
LOC678910 similar to CG9967-PA, isoform A 0.063
Cav1 caveolin 1, caveolae protein 0.061
Syt11 synaptotagmin XI 0.059
Add1 adducin 1 (alpha) 0.058
Nlgn1 neuroligin 1 0.055
Psma2 proteasome (prosome, macropain) subunit, alpha type 2 0.054
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.054
Gria3 glutamate receptor, ionotrophic, AMPA 3 0.053
Ube2v2 ubiquitin-conjugating enzyme E2 variant 2 0.053
Irs1 insulin receptor substrate 1 0.052
Ctsl1 cathepsin L1 0.051
Sirpa signal-regulatory protein alpha 0.051
Gcn1l1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) 0.049
Pnlip pancreatic lipase 0.048
Sorbs2 sorbin and SH3 domain containing 2 0.047
Acrv1 acrosomal vesicle protein 1 0.047
Dnm1 dynamin 1 0.047
Chn1 chimerin (chimaerin) 1 0.046
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.046
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.046
Brcc3 BRCA1/BRCA2-containing complex, subunit 3 0.045
Foxj1 forkhead box J1 0.044
Cpxm2 carboxypeptidase X (M14 family), member 2 0.044
Ptafr platelet-activating factor receptor 0.043
Atp5d ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 0.043
Jdp2 Jun dimerization protein 2 0.043
Actn4 actinin alpha 4 0.043
Ccr5 chemokine (C-C motif) receptor 5 0.043
Map2 microtubule-associated protein 2 0.043
Prkch protein kinase C, eta 0.042
Prrx1 paired related homeobox 1 0.042
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.042
Gnai1 guanine nucleotide binding protein (G protein), alpha inhibiting 1 0.041
RGD1311493 similar to CG13379-PA 0.041
Pitpna phosphatidylinositol transfer protein, alpha 0.040
Rnase4 ribonuclease, RNase A family 4 0.040
Apba1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.040
Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 0.039
Nmt1 N-myristoyltransferase 1 0.039
Lrrc59 leucine rich repeat containing 59 0.039
Tpd52 tumor protein D52 0.038
Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) 0.038
Jak1 Janus kinase 1 0.038
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.037
Gas7 growth arrest specific 7 0.037
Tgfbr2 transforming growth factor, beta receptor II 0.037
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.037
Bgn biglycan 0.036
Gak cyclin G associated kinase 0.036
Trim28 tripartite motif-containing 28 0.036
Sept7 septin 7 0.036
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.036
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.036
Odf4 outer dense fiber of sperm tails 4 0.035
Gabrg3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.035
Eef2 eukaryotic translation elongation factor 2 0.035
Mmp9 matrix metallopeptidase 9 0.034
Litaf lipopolysaccharide-induced TNF factor 0.034
Egfr epidermal growth factor receptor 0.034
Ednrb endothelin receptor type B 0.034
Grasp GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.034
Rps2 ribosomal protein S2 0.033
Mprip myosin phosphatase Rho interacting protein 0.033
Ibsp integrin-binding sialoprotein 0.033
Sox13 SRY (sex determining region Y)-box 13 0.033
Ctss cathepsin S 0.033
Il5 interleukin 5 0.032
Stx3 syntaxin 3 0.032
Srpx sushi-repeat-containing protein, X-linked 0.032
Ddx1 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 0.032
Garnl1 GTPase activating Rap/RanGAP domain-like 1 0.032
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
MYO5 Myo5p 0.074
SLA1 Sla1p 0.058
SLA2 Sla2p 0.056
PAN1 Pan1p 0.050
CCT6 Cct6p 0.038
PWP1 Pwp1p 0.026
PRP43 Prp43p 0.025
SKP1 Skp1p 0.025
AKL1 Akl1p 0.022
PRT1 Prt1p 0.018
NOG2 Nog2p 0.017
MRT4 Mrt4p 0.017
RRP5 Rrp5p 0.017
ABP1 Abp1p 0.016
NOP58 Nop58p 0.015
SNU114 Snu114p 0.015
END3 End3p 0.015
SUP45 Sup45p 0.014
PWP2 Pwp2p 0.014
CCT3 Cct3p 0.014
LAS17 Las17p 0.013
CCT8 Cct8p 0.012
RRP9 Rrp9p 0.012
PAT1 Pat1p 0.012
NOP7 Nop7p 0.012
NOP56 Nop56p 0.012
CHC1 Chc1p 0.012
MRS6 Mrs6p 0.011
NIP1 Nip1p 0.011
FUN12 Fun12p 0.011
ARC40 Arc40p 0.011
DHH1 Dhh1p 0.011
PRK1 Prk1p 0.010