IMP
Process View
The network for 'regulation of rap protein signal transduction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of rap protein signal transduction
Any process that modulates the frequency, rate or extent of Rap protein signal transduction.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.884 | |
| ABI1 | abl-interactor 1 | 0.722 | |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.597 | |
| RAP1A | RAP1A, member of RAS oncogene family | 0.472 | |
| RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.443 | |
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.394 | |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.391 | |
| CLASP1 | cytoplasmic linker associated protein 1 | 0.390 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.367 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.290 | |
| DNM2 | dynamin 2 | 0.138 | |
| DNM1 | dynamin 1 | 0.132 | |
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.116 | |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.110 | |
| MEOX2 | mesenchyme homeobox 2 | 0.086 | |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.076 | |
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.069 | |
| LAT | linker for activation of T cells | 0.069 | |
| WASL | Wiskott-Aldrich syndrome-like | 0.068 | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.067 | |
| GAB1 | GRB2-associated binding protein 1 | 0.054 | |
| GAB2 | GRB2-associated binding protein 2 | 0.051 | |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.049 | |
| ITSN2 | intersectin 2 | 0.047 | |
| STK4 | serine/threonine kinase 4 | 0.047 | |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.041 | |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.041 | |
| PKN2 | protein kinase N2 | 0.041 | |
| RALGDS | ral guanine nucleotide dissociation stimulator | 0.040 | |
| PTCHD2 | patched domain containing 2 | 0.036 | |
| CBLB | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 0.035 | |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.032 | |
| ATP8 | ATP synthase F0 subunit 8 | 0.029 | |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.029 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.026 | |
| RHEB | Ras homolog enriched in brain | 0.025 | |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.024 | |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.024 | |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.023 | |
| BAG1 | BCL2-associated athanogene | 0.022 | |
| CSNK1G2 | casein kinase 1, gamma 2 | 0.022 | |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.022 | |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | 0.021 | |
| LY6G6F | lymphocyte antigen 6 complex, locus G6F | 0.021 | |
| ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.021 | |
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.020 | |
| PEBP4 | phosphatidylethanolamine-binding protein 4 | 0.020 | |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.020 | |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.018 | |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.017 | |
| FGFR1 | fibroblast growth factor receptor 1 | 0.017 | |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.016 | |
| PTPRA | protein tyrosine phosphatase, receptor type, A | 0.016 | |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.016 | |
| SH3PXD2A | SH3 and PX domains 2A | 0.015 | |
| BCR | breakpoint cluster region | 0.015 | |
| KRT8 | keratin 8 | 0.014 | |
| RHOU | ras homolog gene family, member U | 0.013 | |
| PLCG1 | phospholipase C, gamma 1 | 0.013 | |
| STK3 | serine/threonine kinase 3 | 0.013 | |
| SECISBP2L | SECIS binding protein 2-like | 0.013 | |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.012 | |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.012 | |
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.012 | |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit | 0.012 | |
| REPS2 | RALBP1 associated Eps domain containing 2 | 0.011 | |
| CORO1C | coronin, actin binding protein, 1C | 0.011 | |
| NEB | nebulin | 0.011 | |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.010 |
Loading network...
Drosophila melanogaster
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| phl | pole hole | 0.131 | |
| rl | rolled | 0.122 | |
| Pten | CG5671 gene product from transcript CG5671-RB | 0.094 | |
| Ephrin | CG1862 gene product from transcript CG1862-RA | 0.045 | |
| cno | canoe | 0.023 | |
| arm | armadillo | 0.022 | |
| aop | anterior open | 0.021 | |
| N | Notch | 0.020 | |
| tkv | thickveins | 0.017 | |
| Pi3K92E | CG4141 gene product from transcript CG4141-RB | 0.016 | |
| Cdc42 | CG12530 gene product from transcript CG12530-RA | 0.016 | |
| spi | spitz | 0.015 | |
| Pkn | Protein kinase related to protein kinase N | 0.014 | |
| ed | echinoid | 0.013 | |
| Rbf | Retinoblastoma-family protein | 0.013 | |
| Egfr | Epidermal growth factor receptor | 0.013 | |
| Rheb | CG1081 gene product from transcript CG1081-RA | 0.012 | |
| Stat92E | Signal-transducer and activator of transcription protein at 92E | 0.012 | |
| dos | daughter of sevenless | 0.011 | |
| CdsA | CDP diglyceride synthetase | 0.011 | |
| Src64B | Src oncogene at 64B | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Efnb2 | ephrin B2 | 0.887 | |
| Ephb2 | Eph receptor B2 | 0.756 | |
| Epha4 | Eph receptor A4 | 0.743 | |
| Ephb3 | Eph receptor B3 | 0.224 | |
| Efnb1 | ephrin B1 | 0.096 | |
| Braf | Braf transforming gene | 0.043 | |
| Hprt | hypoxanthine guanine phosphoribosyl transferase | 0.040 | |
| Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.039 | |
| Arhgef15 | Rho guanine nucleotide exchange factor (GEF) 15 | 0.036 | |
| Trim33 | tripartite motif-containing 33 | 0.036 | |
| Raf1 | v-raf-leukemia viral oncogene 1 | 0.030 | |
| Kcnk2 | potassium channel, subfamily K, member 2 | 0.025 | |
| Cdc42ep1 | CDC42 effector protein (Rho GTPase binding) 1 | 0.021 | |
| Nf1 | neurofibromatosis 1 | 0.021 | |
| Pten | phosphatase and tensin homolog | 0.020 | |
| Grip1 | glutamate receptor interacting protein 1 | 0.017 | |
| Gata5 | GATA binding protein 5 | 0.016 | |
| Ptp4a2 | protein tyrosine phosphatase 4a2 | 0.015 | |
| Sept7 | septin 7 | 0.013 | |
| Tmeff2 | transmembrane protein with EGF-like and two follistatin-like domains 2 | 0.013 | |
| Tnks1bp1 | tankyrase 1 binding protein 1 | 0.013 | |
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.012 | |
| Plxna2 | plexin A2 | 0.011 | |
| Irs1 | insulin receptor substrate 1 | 0.011 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.011 | |
| Sh3rf1 | SH3 domain containing ring finger 1 | 0.010 | |
| Grb2 | growth factor receptor bound protein 2 | 0.010 |