The network for 'cyclic nucleotide biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cyclic nucleotide biosynthetic process

The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.

Mus musculus
Name Description Probability Func Analog Organism
Esr1 estrogen receptor 1 (alpha) 0.981
Cckbr cholecystokinin B receptor 0.892
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.856
Ar androgen receptor 0.844
Drd2 dopamine receptor D2 0.701
Pax8 paired box gene 8 0.676
Adrb1 adrenergic receptor, beta 1 0.645
Pgr progesterone receptor 0.499
Kl klotho 0.433
Pten phosphatase and tensin homolog 0.417
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.396
Pnpla2 patatin-like phospholipase domain containing 2 0.357
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.340
Npc1 Niemann Pick type C1 0.335
Crhr1 corticotropin releasing hormone receptor 1 0.333
Gjb5 gap junction protein, beta 5 0.320
Adora2a adenosine A2a receptor 0.313
Nfatc2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.312
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.279
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.273
Gnrh1 gonadotropin releasing hormone 1 0.251
Prlr prolactin receptor 0.246
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.236
Tshr thyroid stimulating hormone receptor 0.233
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.232
Hand1 heart and neural crest derivatives expressed transcript 1 0.222
Shc3 src homology 2 domain-containing transforming protein C3 0.219
Hif1a hypoxia inducible factor 1, alpha subunit 0.216
Vdr vitamin D receptor 0.207
Plxnd1 plexin D1 0.200
Opn1sw opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) 0.196
Slc16a8 solute carrier family 16 (monocarboxylic acid transporters), member 8 0.193
Ghr growth hormone receptor 0.187
Amh anti-Mullerian hormone 0.182
Htr4 5 hydroxytryptamine (serotonin) receptor 4 0.180
Pthlh parathyroid hormone-like peptide 0.180
Galr1 galanin receptor 1 0.172
Ctnnb1 catenin (cadherin associated protein), beta 1 0.169
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.167
Syn2 synapsin II 0.167
Nrp1 neuropilin 1 0.157
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.156
Sstr4 somatostatin receptor 4 0.156
Smad2 MAD homolog 2 (Drosophila) 0.154
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.151
Wnt2b wingless related MMTV integration site 2b 0.151
Grm1 glutamate receptor, metabotropic 1 0.146
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.144
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.144
Ednra endothelin receptor type A 0.143
Cdh6 cadherin 6 0.142
Grid1 glutamate receptor, ionotropic, delta 1 0.140
Cntn4 contactin 4 0.137
Thra thyroid hormone receptor alpha 0.136
Kiss1 KiSS-1 metastasis-suppressor 0.135
C1qtnf1 C1q and tumor necrosis factor related protein 1 0.134
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.133
Prkce protein kinase C, epsilon 0.131
Mc5r melanocortin 5 receptor 0.130
Abcg1 ATP-binding cassette, sub-family G (WHITE), member 1 0.130
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.129
Bmp10 bone morphogenetic protein 10 0.124
Pomc pro-opiomelanocortin-alpha 0.123
Prkaca protein kinase, cAMP dependent, catalytic, alpha 0.122
Prop1 paired like homeodomain factor 1 0.120
Aatk apoptosis-associated tyrosine kinase 0.118
Nos3 nitric oxide synthase 3, endothelial cell 0.117
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.117
Foxi3 forkhead box I3 0.114
Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 0.114
Cplx1 complexin 1 0.113
Lhx6 LIM homeobox protein 6 0.113
Npy5r neuropeptide Y receptor Y5 0.113
Rgs9 regulator of G-protein signaling 9 0.112
Fyn Fyn proto-oncogene 0.112
Htr1d 5-hydroxytryptamine (serotonin) receptor 1D 0.112
Kcnc1 potassium voltage gated channel, Shaw-related subfamily, member 1 0.110
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.110
Lrp1 low density lipoprotein receptor-related protein 1 0.107
Sntb1 syntrophin, basic 1 0.106
Foxo4 forkhead box O4 0.106
Kcnb1 potassium voltage gated channel, Shab-related subfamily, member 1 0.106
Oprm1 opioid receptor, mu 1 0.105
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.105
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.104
Lep leptin 0.104
Acr acrosin prepropeptide 0.104
Ppard peroxisome proliferator activator receptor delta 0.103
Ceacam11 carcinoembryonic antigen-related cell adhesion molecule 11 0.103
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.103
Fndc7 fibronectin type III domain containing 7 0.102
Klf7 Kruppel-like factor 7 (ubiquitous) 0.099
Bcar1 breast cancer anti-estrogen resistance 1 0.099
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.099
Itga2 integrin alpha 2 0.099
Neurog3 neurogenin 3 0.097
Sstr1 somatostatin receptor 1 0.096
Kcnk3 potassium channel, subfamily K, member 3 0.096
Guca2b guanylate cyclase activator 2b (retina) 0.096
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.094
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
tax-4 Protein TAX-4 0.877
gcy-22 Protein GCY-22 0.299
tax-2 Protein TAX-2 0.245
dbl-1 Protein DBL-1 0.240
E02A10.3 Protein E02A10.3 0.215
cal-4 Protein CAL-4 0.214
che-1 Protein CHE-1 0.179
daf-11 Protein DAF-11 0.174
sol-1 Protein SOL-1 0.170
odr-3 Protein ODR-3 0.153
osm-3 Protein OSM-3 0.118
nlp-15 Protein NLP-15 0.100
cpx-1 Protein CPX-1 0.090
pkg-1 Protein PKG-1 0.088
unc-43 Protein UNC-43 0.075
F46C5.2 Protein F46C5.2 0.074
gcy-6 Protein GCY-6 0.073
snt-4 Protein SNT-4 0.069
oig-1 Protein OIG-1 0.068
pde-4 Protein PDE-4 0.062
F46B6.9 Protein F46B6.9 0.059
tax-6 Protein TAX-6 0.048
cal-1 Protein CAL-1 0.047
unc-103 Protein UNC-103 0.044
frm-1 Protein FRM-1 0.043
twk-30 Protein TWK-30 0.042
unc-13 Protein UNC-13 0.042
pry-1 Protein PRY-1 0.041
C01H6.3 Protein C01H6.3 0.041
twk-49 Protein TWK-49 0.041
che-3 Protein CHE-3 0.040
lron-5 Protein LRON-5 0.040
egl-30 Protein EGL-30 0.039
T19D2.3 Protein T19D2.3 0.039
Y72A10A.1 Protein Y72A10A.1 0.039
dac-1 Protein DAC-1 0.038
kvs-2 Protein KVS-2 0.037
che-2 Protein CHE-2 0.037
F07C3.2 Protein F07C3.2 0.036
lpin-1 Protein LPIN-1 0.036
W05B5.1 Protein W05B5.1 0.035
daf-7 Protein DAF-7 0.034
T05H10.8 Protein T05H10.8 0.033
F57C7.4 Protein F57C7.4 0.033
acr-2 Protein ACR-2 0.033
glr-4 Protein GLR-4 0.032
npr-2 Protein NPR-2 0.032
unc-79 Protein UNC-79 0.032
H18N23.2 Protein H18N23.2 0.031
F01G12.6 Protein F01G12.6 0.031
ser-7 Protein SER-7 0.031
sri-11 Protein SRI-11 0.031
itr-1 Protein ITR-1 0.030
fkh-9 Protein FKH-9 0.030
CELE_K03H1.5 Protein K03H1.5 0.030
CELE_T28B8.3 Protein T28B8.3 0.029
ZK669.5 Protein ZK669.5 0.029
fln-1 Protein FLN-1 0.027
pqn-18 Protein PQN-18 0.027
ser-2 Protein SER-2 0.027
hlh-29 Protein HLH-29 0.026
inx-19 Protein INX-19 0.025
sng-1 Protein SNG-1 0.025
acr-15 Protein ACR-15 0.025
CELE_Y64G10A.6 Protein Y64G10A.6 0.025
npr-4 Protein NPR-4 0.025
tag-147 Protein TAG-147 0.024
Y43E12A.2 Protein Y43E12A.2 0.023
F21D12.3 Protein F21D12.3 0.023
srx-36 Protein SRX-36 0.023
C06E7.2 Protein C06E7.2 0.023
tom-1 Protein TOM-1 0.023
glr-5 Protein GLR-5 0.023
pph-1 Protein PPH-1 0.022
C14A4.13 Protein C14A4.13 0.022
math-41 Protein MATH-41 0.022
ser-4 Protein SER-4 0.022
ser-3 Protein SER-3 0.021
R03G5.3 Protein R03G5.3 0.021
col-105 Protein COL-105 0.021
arrd-15 Protein ARRD-15 0.021
CELE_T09E11.3 Protein T09E11.3 0.021
rnt-1 Protein RNT-1 0.021
sri-38 Protein SRI-38 0.021
CELE_Y75B8A.13 Protein Y75B8A.13 0.021
Y48G9A.9 Protein Y48G9A.9 0.020
srx-16 Protein SRX-16 0.020
ncr-1 Protein NCR-1 0.020
CELE_K09C4.6 Protein K09C4.6 0.020
CELE_T11A5.6 Protein T11A5.6 0.020
unc-24 Protein UNC-24 0.019
tph-1 Protein TPH-1 0.019
Y57A10B.1 Protein Y57A10B.1 0.019
Y37A1A.3 Protein Y37A1A.3 0.019
str-246 Protein STR-246 0.019
rga-6 Protein RGA-6 0.019
glb-12 Protein GLB-12 0.019
ain-2 Protein AIN-2 0.019
B0478.3 Protein B0478.3 0.019
pitp-1 Protein PITP-1 0.019
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Danio rerio
Name Description Probability Func Analog Organism
uts1 urotensin 1 0.990
avpl arginine vasopressin-like 0.926
mc2r melanocortin 2 receptor 0.882
mc4r melanocortin 4 receptor 0.646
oxtl oxytocin-like 0.598
vipr2 vasoactive intestinal peptide receptor 2 0.554
adrb2a adrenergic receptor, beta 2a 0.524
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.500
fshr follicle stimulating hormone receptor 0.409
drd2a dopamine receptor D2a 0.409
LOC569642 hypothetical protein LOC569642 0.403
adra2b adrenergic, alpha-2B-, receptor 0.369
si:dkey-228g21.4 si:dkey-228g21.4 0.333
rag1 recombination activating gene 1 0.321
nf1a neurofibromin 1a 0.305
hcrtr2 hypocretin (orexin) receptor 2 0.299
LOC555482 tachykinin receptor 3-like 0.293
cyp11b2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.278
gucy2f guanylate cyclase 2F, retinal 0.271
drd3 dopamine receptor D3 0.257
LOC559201 similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3) 0.249
mpp5b membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5b) 0.215
tert telomerase reverse transcriptase 0.210
drd2b dopamine receptor D2b 0.199
nlgn4a neuroligin 4a 0.189
sox4b SRY-box containing gene 4b 0.174
adra2db adrenergic, alpha-2D-, receptor b 0.172
nf1b neurofibromin 1b 0.145
ros1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) 0.140
fes feline sarcoma oncogene 0.138
ptpra protein tyrosine phosphatase, receptor type, A 0.133
npy8br neuropeptide Y receptor Y8b 0.132
c1qtnf4 C1q and tumor necrosis factor related protein 4 0.128
kiss1rb KISS1 receptor b 0.125
dbh dopamine beta hydroxylase 0.107
dclk2 doublecortin-like kinase 2 0.101
adrb1 adrenergic receptor, beta 1 0.097
alx4a aristaless-like homeobox 4a 0.097
sst3 somatostatin 3 0.092
slc8a4b solute carrier family 8 (sodium/calcium exchanger), member 4b 0.090
bmp8a bone morphogenetic protein 8a 0.090
rag2 recombination activating gene 2 0.087
lifrb leukemia inhibitory factor receptor alpha b 0.087
gc2 guanylyl cyclase 2 0.086
diaph2 diaphanous homolog 2 (Drosophila) 0.086
si:ch211-209p5.2 si:ch211-209p5.2 0.085
rtn1a reticulon 1a 0.082
rx1 retinal homeobox gene 1 0.081
mchr1b melanin-concentrating hormone receptor 1b 0.080
lepr leptin receptor 0.076
hmgb1a high-mobility group box 1a 0.074
atp1b2a ATPase, Na+/K+ transporting, beta 2a polypeptide 0.074
cx55.5 connexin 55.5 0.074
adra2c adrenergic, alpha-2C-, receptor 0.072
mchr1a melanin-concentrating hormone receptor 1a 0.071
adcyap1r1a adenylate cyclase activating polypeptide 1 receptor 1a 0.071
drd2l dopamine receptor D2 like 0.069
tspan7b tetraspanin 7b 0.068
zgc:65851 zgc:65851 0.066
flj13639 flj13639 0.065
mc1r melanocortin 1 receptor 0.064
hcrt hypocretin (orexin) neuropeptide precursor 0.061
mstnb myostatin b 0.060
gnrh2 gonadotropin-releasing hormone 2 0.059
paqr8 progestin and adipoQ receptor family member VIII 0.058
LOC563363 cholesterol side-chain cleavage enzyme, mitochondrial-like 0.056
pp pyrophosphatase (inorganic) 0.056
gnat1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.056
adra2da adrenergic, alpha-2D-, receptor a 0.054
trpc1 transient receptor potential cation channel, subfamily C, member 1 0.053
atp6v0cb ATPase, H+ transporting, lysosomal, V0 subunit c, b 0.052
esr1 estrogen receptor 1 0.052
guca1c guanylate cyclase activator 1C 0.051
opn1lw1 opsin 1 (cone pigments), long-wave-sensitive, 1 0.051
ryr2a ryanodine receptor 2a (cardiac) 0.050
plxnb2a plexin b2a 0.050
ncs1a neuronal calcium sensor 1a 0.048
grk7a G-protein-coupled receptor kinase 7a 0.047
penka proenkephalin a 0.046
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.042
otpa orthopedia homolog a 0.042
prkcea protein kinase C, epsilon a 0.039
mc5rb melanocortin 5b receptor 0.037
arr3a arrestin 3a, retinal (X-arrestin) 0.035
si:dkeyp-59a8.4 si:dkeyp-59a8.4 0.035
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.034
mc5ra melanocortin 5a receptor 0.034
prdm15 PR domain containing 15 0.034
htr1aa 5-hydroxytryptamine (serotonin) receptor 1A a 0.034
uts2b urotensin 2, beta 0.034
saga S-antigen; retina and pineal gland (arrestin) a 0.033
LOC555504 novel protocadherin protein 0.033
bsk146 brain specific kinase 146 0.033
synj1 synaptojanin 1 0.033
adora2b adenosine A2b receptor 0.033
gap43 growth associated protein 43 0.033
clock clock 0.032
opn4l opsin 4, like 0.032
spock3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 0.031
crygm4 crystallin, gamma M4 0.031
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Tbh Tyramine beta hydroxylase 0.964
dnc dunce 0.951
Pde8 Phosphodiesterase 8 0.923
CG42629 CG42629 gene product from transcript CG42629-RB 0.912
wit wishful thinking 0.903
Nmdar1 NMDA receptor 1 0.896
Shaw Shaker cognate w 0.877
Octbeta2R CG33976 gene product from transcript CG33976-RA 0.866
CG13253 CG13253 gene product from transcript CG13253-RB 0.817
tim timeless 0.809
Gyc-89Db Guanylyl cyclase at 89Db 0.759
Rheb CG1081 gene product from transcript CG1081-RA 0.738
CaMKII Calcium/calmodulin-dependent protein kinase II 0.718
Gyc-89Da Guanylyl cyclase at 89Da 0.673
unc-13 CG2999 gene product from transcript CG2999-RA 0.544
Mst57Db Male-specific RNA 57Db 0.434
CG14686 CG14686 gene product from transcript CG14686-RA 0.393
CG34400 CG34400 gene product from transcript CG34400-RD 0.366
5-HT1B Serotonin receptor 1B 0.354
tau CG31057 gene product from transcript CG31057-RA 0.344
mtt mangetout 0.322
Ank2 Ankyrin 2 0.296
Gr64e Gustatory receptor 64e 0.293
Actbeta Activin-beta 0.286
G-salpha60A G protein salpha 60A 0.266
Atf-2 Activating transcription factor-2 0.238
CG32813 CG32813 gene product from transcript CG32813-RE 0.236
Frq2 Frequenin 2 0.235
king-tubby king tubby 0.226
Ac76E Adenylyl cyclase 76E 0.220
slo slowpoke 0.208
5-HT1A Serotonin receptor 1A 0.189
Clk Clock 0.189
AdoR Adenosine receptor 0.172
Cng Cyclic-nucleotide-gated ion channel protein 0.171
cals calsyntenin-1 0.151
per period 0.133
Dh Diuretic hormone 0.130
oa2 octopamine receptor 2 0.130
fd85E forkhead domain 85E 0.125
cry cryptochrome 0.122
beta4GalNAcTA CG8536 gene product from transcript CG8536-RA 0.114
G-oalpha47A G protein oalpha 47A 0.112
Gr43a Gustatory receptor 43a 0.112
Sox100B CG15552 gene product from transcript CG15552-RA 0.110
jeb jelly belly 0.110
Ric Ras which interacts with Calmodulin 0.108
Tdc2 Tyrosine decarboxylase 2 0.106
dpr defective proboscis extension response 0.103
dnr1 defense repressor 1 0.102
CG16778 CG16778 gene product from transcript CG16778-RA 0.102
CG18437 CG18437 gene product from transcript CG18437-RB 0.101
GABA-B-R2 metabotropic GABA-B receptor subtype 2 0.090
Spf45 CG17540 gene product from transcript CG17540-RB 0.089
uzip unzipped 0.088
inaD inactivation no afterpotential D 0.088
pdfr PDF receptor 0.087
Gyc88E Guanylyl cyclase at 88E 0.085
eag ether a go-go 0.075
TyrR Tyramine receptor 0.072
Ac3 CG1506 gene product from transcript CG1506-RA 0.070
Ih I[[h]] channel 0.070
KCNQ KCNQ potassium channel 0.067
Gr28b Gustatory receptor 28b 0.061
5-HT7 Serotonin receptor 7 0.060
Dyb Dystrobrevin-like 0.060
CanA1 Calcineurin A1 0.060
CG14864 CG14864 gene product from transcript CG14864-RB 0.059
CG34351 CG34351 gene product from transcript CG34351-RC 0.056
Gr33a Gustatory receptor 33a 0.054
pain painless 0.053
Tre Trehalose-sensitivity 0.052
Dms Dromyosuppressin 0.051
dpr5 CG5308 gene product from transcript CG5308-RA 0.051
Ast-C Allatostatin C 0.051
GABA-B-R3 metabotropic GABA-B receptor subtype 3 0.046
beat-Vb CG31298 gene product from transcript CG31298-RA 0.045
Ilp4 Insulin-like peptide 4 0.043
CG6983 CG6983 gene product from transcript CG6983-RA 0.043
Plc21C Phospholipase C at 21C 0.043
Rdl Resistant to dieldrin 0.042
hig hikaru genki 0.042
Nep3 Neprilysin 3 0.041
NPFR1 neuropeptide F receptor 0.040
SK small conductance calcium-activated potassium channel 0.038
GluRIIB Glutamate receptor IIB 0.037
CG10137 CG10137 gene product from transcript CG10137-RA 0.037
neuroligin CG13772 gene product from transcript CG13772-RA 0.036
Fer2 48 related 2 0.035
CG15088 CG15088 gene product from transcript CG15088-RC 0.035
mGluRA metabotropic glutamate receptor 0.034
CG31191 CG31191 gene product from transcript CG31191-RA 0.033
CG5342 CG5342 gene product from transcript CG5342-RB 0.033
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.032
PIP5K59B CG3682 gene product from transcript CG3682-RE 0.032
CG33714 CG33714 gene product from transcript CG33714-RB 0.032
Nrx-1 Neurexin 1 0.031
CG31146 CG31146 gene product from transcript CG31146-RD 0.031
CG8959 CG8959 gene product from transcript CG8959-RA 0.031
l(3)82Fd CG32464 gene product from transcript CG32464-RR 0.031
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.000
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.999
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.995
ARRB1 arrestin, beta 1 0.994
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.980
DRD2 dopamine receptor D2 0.970
TBXA2R thromboxane A2 receptor 0.961
ADORA2A adenosine A2a receptor 0.953
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.949
FHL1 four and a half LIM domains 1 0.924
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.899
HP haptoglobin 0.883
NOSTRIN nitric oxide synthase trafficker 0.866
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.852
CRHR1 corticotropin releasing hormone receptor 1 0.835
SLC9A3R2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.829
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.809
CBX1 chromobox homolog 1 0.801
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.763
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.737
CRH corticotropin releasing hormone 0.735
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.716
MT1A metallothionein 1A 0.710
TBC1D10A TBC1 domain family, member 10A 0.701
ADRB2 adrenergic, beta-2-, receptor, surface 0.664
MAPT microtubule-associated protein tau 0.620
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.592
GOPC golgi-associated PDZ and coiled-coil motif containing 0.568
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.550
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.539
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.534
GFI1B growth factor independent 1B transcription repressor 0.533
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.531
NME1 non-metastatic cells 1, protein (NM23A) expressed in 0.522
CD34 CD34 molecule 0.519
FYN FYN oncogene related to SRC, FGR, YES 0.514
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.500
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.457
PDZK1 PDZ domain containing 1 0.425
VAC14 Vac14 homolog (S. cerevisiae) 0.402
MEOX2 mesenchyme homeobox 2 0.402
EZR ezrin 0.375
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.353
PTEN phosphatase and tensin homolog 0.333
PDCD6IP programmed cell death 6 interacting protein 0.327
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.312
GPR6 G protein-coupled receptor 6 0.311
FKBP8 FK506 binding protein 8, 38kDa 0.305
AR androgen receptor 0.290
EGFL7 EGF-like-domain, multiple 7 0.265
LCAT lecithin-cholesterol acyltransferase 0.265
ADORA1 adenosine A1 receptor 0.264
RALBP1 ralA binding protein 1 0.255
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.245
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.238
GHRHR growth hormone releasing hormone receptor 0.237
DEAF1 deformed epidermal autoregulatory factor 1 (Drosophila) 0.221
MTNR1A melatonin receptor 1A 0.220
APOC1 apolipoprotein C-I 0.213
CLDN5 claudin 5 0.210
RALGDS ral guanine nucleotide dissociation stimulator 0.207
CDV3 CDV3 homolog (mouse) 0.204
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.198
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.194
CXCR5 chemokine (C-X-C motif) receptor 5 0.194
PCDHA4 protocadherin alpha 4 0.194
PDZD3 PDZ domain containing 3 0.192
GLP1R glucagon-like peptide 1 receptor 0.191
NME4 non-metastatic cells 4, protein expressed in 0.189
NSF N-ethylmaleimide-sensitive factor 0.184
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.180
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 0.179
NME3 non-metastatic cells 3, protein expressed in 0.178
BZW1 basic leucine zipper and W2 domains 1 0.174
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.166
ELAVL3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) 0.159
A2M alpha-2-macroglobulin 0.157
SSTR4 somatostatin receptor 4 0.153
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.150
BCR breakpoint cluster region 0.150
FAM107A family with sequence similarity 107, member A 0.144
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.140
CALCRL calcitonin receptor-like 0.138
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.137
CRHR2 corticotropin releasing hormone receptor 2 0.136
GFAP glial fibrillary acidic protein 0.131
SLC6A7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 0.130
RIN1 Ras and Rab interactor 1 0.130
BCAR1 breast cancer anti-estrogen resistance 1 0.128
GMFB glia maturation factor, beta 0.127
ADRB3 adrenergic, beta-3-, receptor 0.126
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.124
ACHE acetylcholinesterase 0.121
KCNF1 potassium voltage-gated channel, subfamily F, member 1 0.117
CALCR calcitonin receptor 0.116
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.115
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B 0.114
PDE4DIP phosphodiesterase 4D interacting protein 0.111
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A 0.109
NCOA2 nuclear receptor coactivator 2 0.108
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Olr416 olfactory receptor 416 0.396
Cd63 Cd63 molecule 0.321
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.314
Prp15 proline-rich protein 15 0.291
Hrh3 histamine receptor H3 0.273
Gucy1a3 guanylate cyclase 1, soluble, alpha 3 0.245
Fgf14 fibroblast growth factor 14 0.244
Prlhr prolactin releasing hormone receptor 0.244
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.229
Anxa5 annexin A5 0.198
Nfasc neurofascin 0.185
Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) 0.185
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.172
Olr287 olfactory receptor 287 0.160
Scn10a sodium channel, voltage-gated, type X, alpha subunit 0.159
Calcr calcitonin receptor 0.152
Vipr2 vasoactive intestinal peptide receptor 2 0.141
Cmklr1 chemokine-like receptor 1 0.137
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.135
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.124
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.122
Gpr6 G protein-coupled receptor 6 0.121
Odf4 outer dense fiber of sperm tails 4 0.120
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.120
Chat choline acetyltransferase 0.118
Gpr1 G protein-coupled receptor 1 0.117
Grin3a glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.117
Adra2c adrenergic, alpha-2C-, receptor 0.114
Clstn3 calsyntenin 3 0.111
Notch3 Notch homolog 3 (Drosophila) 0.107
Calm1 calmodulin 1 0.104
Syp synaptophysin 0.104
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.103
Sema4f sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 0.102
Slc16a8 solute carrier family 16, member 8 (monocarboxylic acid transporter 3) 0.102
Lpcat4 lysophosphatidylcholine acyltransferase 4 0.100
Slc18a3 solute carrier family 18 (vesicular acetylcholine), member 3 0.100
Hcrt hypocretin 0.099
Olr1356 olfactory receptor 1356 0.096
Drd2 dopamine receptor D2 0.096
Syt7 synaptotagmin VII 0.095
Vcsa1 variable coding sequence A1 0.095
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.093
Avpr1b arginine vasopressin receptor 1B 0.093
Lrpap1 low density lipoprotein receptor-related protein associated protein 1 0.092
Prph2 peripherin 2 0.090
Adora2a adenosine A2a receptor 0.089
Flt1 FMS-related tyrosine kinase 1 0.088
Cckar cholecystokinin A receptor 0.088
Cpne5 copine V 0.087
Crhbp corticotropin releasing hormone binding protein 0.086
Clcn3 chloride channel 3 0.085
Tacr1 tachykinin receptor 1 0.084
Trhr thyrotropin releasing hormone receptor 0.083
Cxcr5 chemokine (C-X-C motif) receptor 5 0.083
Lamb2 laminin, beta 2 0.081
Nrsn1 neurensin 1 0.081
Vom2r32 vomeronasal 2 receptor, 32 0.080
Ube2d4 ubiquitin-conjugating enzyme E2D 4 0.080
Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.080
Kalrn kalirin, RhoGEF kinase 0.079
Hrh2 histamine receptor H 2 0.079
Hpcal4 hippocalcin-like 4 0.078
Grin2d glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.077
Gpr88 G-protein coupled receptor 88 0.077
Gabrr3 gamma-aminobutyric acid (GABA) receptor, rho 3 0.077
Chrna3 cholinergic receptor, nicotinic, alpha 3 0.075
Fgb fibrinogen beta chain 0.075
Tef thyrotrophic embryonic factor 0.075
Krtap1-5 keratin associated protein 1-5 0.074
Dlg4 discs, large homolog 4 (Drosophila) 0.073
Slc6a7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 0.072
Ncan neurocan 0.072
Vom2r44 vomeronasal 2 receptor 44 0.071
Epor erythropoietin receptor 0.071
Cx3cr1 chemokine (C-X3-C motif) receptor 1 0.070
Gal galanin prepropeptide 0.069
Krt34 keratin 34 0.069
Ecel1 endothelin converting enzyme-like 1 0.068
Kctd13 potassium channel tetramerisation domain containing 13 0.068
Arhgap23 Rho GTPase activating protein 23 0.068
Aqp2 aquaporin 2 (collecting duct) 0.068
Clcn1 chloride channel 1 0.068
Kcna3 potassium voltage-gated channel, shaker-related subfamily, member 3 0.067
Sub1 SUB1 homolog (S. cerevisiae) 0.067
Opn1sw opsin 1 (cone pigments), short-wave-sensitive 0.066
Pmch pro-melanin-concentrating hormone 0.066
Necab2 N-terminal EF-hand calcium binding protein 2 0.066
Aplnr apelin receptor 0.066
Grip2 glutamate receptor interacting protein 2 0.065
Impg2 interphotoreceptor matrix proteoglycan 2 0.065
Krt86 keratin 86 0.064
Sh2d3c SH2 domain containing 3C 0.064
Sgp158 proline-rich glycoprotein (sgp158) 0.063
Pnoc prepronociceptin 0.063
Cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.063
Acan aggrecan 0.062
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.061
Cartpt CART prepropeptide 0.061
Nrg1 neuregulin 1 0.061
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism