IMP
Process View
The network for 'negative regulation of sterol transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of sterol transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.936 | |
| Traf6 | TNF receptor-associated factor 6 | 0.827 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.791 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.740 | |
| Ihh | Indian hedgehog | 0.739 | |
| Mep1a | meprin 1 alpha | 0.729 | |
| Ldlr | low density lipoprotein receptor | 0.546 | |
| Gata4 | GATA binding protein 4 | 0.497 | |
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.410 | |
| Axin1 | axin 1 | 0.396 | |
| Abcg8 | ATP-binding cassette, sub-family G (WHITE), member 8 | 0.377 | |
| Npc1 | Niemann Pick type C1 | 0.374 | |
| Shh | sonic hedgehog | 0.358 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.345 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.331 | |
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.290 | |
| Pten | phosphatase and tensin homolog | 0.260 | |
| Abcg5 | ATP-binding cassette, sub-family G (WHITE), member 5 | 0.246 | |
| Cyp27b1 | cytochrome P450, family 27, subfamily b, polypeptide 1 | 0.215 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.208 | |
| Klf15 | Kruppel-like factor 15 | 0.205 | |
| Agtr2 | angiotensin II receptor, type 2 | 0.194 | |
| Tbx3 | T-box 3 | 0.191 | |
| T | brachyury | 0.186 | |
| Col4a3 | collagen, type IV, alpha 3 | 0.146 | |
| Pla2g10 | phospholipase A2, group X | 0.142 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.133 | |
| Atp4a | ATPase, H+/K+ exchanging, gastric, alpha polypeptide | 0.133 | |
| Runx2 | runt related transcription factor 2 | 0.132 | |
| Tex19.2 | testis expressed gene 19.2 | 0.128 | |
| Lep | leptin | 0.128 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.123 | |
| Slc6a20b | solute carrier family 6 (neurotransmitter transporter), member 20B | 0.122 | |
| Egfr | epidermal growth factor receptor | 0.122 | |
| Krtap5-1 | keratin associated protein 5-1 | 0.121 | |
| Nkx2-1 | NK2 homeobox 1 | 0.118 | |
| Kcnq1 | potassium voltage-gated channel, subfamily Q, member 1 | 0.118 | |
| Sertad2 | SERTA domain containing 2 | 0.117 | |
| Pkd1 | polycystic kidney disease 1 homolog | 0.111 | |
| Slc22a2 | solute carrier family 22 (organic cation transporter), member 2 | 0.108 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.103 | |
| Zp2 | zona pellucida glycoprotein 2 | 0.098 | |
| Bmp4 | bone morphogenetic protein 4 | 0.094 | |
| Gsk3b | glycogen synthase kinase 3 beta | 0.091 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.089 | |
| Pick1 | protein interacting with C kinase 1 | 0.087 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.086 | |
| Nr0b2 | nuclear receptor subfamily 0, group B, member 2 | 0.086 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.085 | |
| Sct | secretin | 0.083 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.082 | |
| Cdon | cell adhesion molecule-related/down-regulated by oncogenes | 0.076 | |
| Cubn | cubilin (intrinsic factor-cobalamin receptor) | 0.075 | |
| Lgals2 | lectin, galactose-binding, soluble 2 | 0.075 | |
| Slc7a9 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 | 0.074 | |
| Apoa1 | apolipoprotein A-I | 0.073 | |
| Col4a4 | collagen, type IV, alpha 4 | 0.070 | |
| App | amyloid beta (A4) precursor protein | 0.067 | |
| Psen1 | presenilin 1 | 0.066 | |
| Zp3 | zona pellucida glycoprotein 3 | 0.065 | |
| Tff1 | trefoil factor 1 | 0.063 | |
| Wap | whey acidic protein | 0.060 | |
| Kcnk7 | potassium channel, subfamily K, member 7 | 0.059 | |
| Srf | serum response factor | 0.059 | |
| Sox13 | SRY-box containing gene 13 | 0.059 | |
| Peli2 | pellino 2 | 0.058 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.058 | |
| Il1r1 | interleukin 1 receptor, type I | 0.058 | |
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.057 | |
| Foxa2 | forkhead box A2 | 0.057 | |
| Scarb1 | scavenger receptor class B, member 1 | 0.055 | |
| Lpin1 | lipin 1 | 0.054 | |
| Gsg1 | germ cell-specific gene 1 | 0.053 | |
| Mertk | c-mer proto-oncogene tyrosine kinase | 0.053 | |
| Fgf9 | fibroblast growth factor 9 | 0.052 | |
| Smpd3 | sphingomyelin phosphodiesterase 3, neutral | 0.052 | |
| Otog | otogelin | 0.051 | |
| Lrp5 | low density lipoprotein receptor-related protein 5 | 0.051 | |
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.050 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.049 | |
| Clcnka | chloride channel Ka | 0.049 | |
| Itga3 | integrin alpha 3 | 0.048 | |
| Lyz2 | lysozyme 2 | 0.048 | |
| Spam1 | sperm adhesion molecule 1 | 0.048 | |
| Tulp2 | tubby-like protein 2 | 0.048 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.046 | |
| Cdh16 | cadherin 16 | 0.046 | |
| Fabp2 | fatty acid binding protein 2, intestinal | 0.046 | |
| Capn9 | calpain 9 | 0.046 | |
| Pla2g2c | phospholipase A2, group IIC | 0.045 | |
| Lrp4 | low density lipoprotein receptor-related protein 4 | 0.042 | |
| Sox3 | SRY-box containing gene 3 | 0.042 | |
| Cox8c | cytochrome c oxidase, subunit VIIIc | 0.041 | |
| Clps | colipase, pancreatic | 0.041 | |
| Hgfac | hepatocyte growth factor activator | 0.041 | |
| Irak4 | interleukin-1 receptor-associated kinase 4 | 0.041 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.040 | |
| Pmel | premelanosome protein | 0.040 | |
| Nags | N-acetylglutamate synthase | 0.040 | |
| Srcrb4d | scavenger receptor cysteine rich domain containing, group B (4 domains) | 0.040 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| ALB | albumin | 1.000 | |
| APOA1 | apolipoprotein A-I | 1.000 | |
| HP | haptoglobin | 0.984 | |
| APOC1 | apolipoprotein C-I | 0.975 | |
| APOE | apolipoprotein E | 0.966 | |
| A2M | alpha-2-macroglobulin | 0.637 | |
| APOA2 | apolipoprotein A-II | 0.621 | |
| APOC3 | apolipoprotein C-III | 0.580 | |
| LCAT | lecithin-cholesterol acyltransferase | 0.529 | |
| TRAF6 | TNF receptor-associated factor 6 | 0.449 | |
| MED15 | mediator complex subunit 15 | 0.315 | |
| APOC2 | apolipoprotein C-II | 0.237 | |
| FGA | fibrinogen alpha chain | 0.162 | |
| TXNDC2 | thioredoxin domain containing 2 (spermatozoa) | 0.064 | |
| AHSG | alpha-2-HS-glycoprotein | 0.039 | |
| TTR | transthyretin | 0.039 | |
| LDLR | low density lipoprotein receptor | 0.037 | |
| PLTP | phospholipid transfer protein | 0.037 | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.024 | |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | 0.021 | |
| APOB | apolipoprotein B (including Ag(x) antigen) | 0.016 | |
| IRAK4 | interleukin-1 receptor-associated kinase 4 | 0.012 |