Process View
The network for 'branching involved in salivary gland morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The process in which the branching structure of the salivary gland is generated and organized.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Axl | AXL receptor tyrosine kinase | 0.998 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.998 | |
| Shh | sonic hedgehog | 0.997 | |
| Lamc1 | laminin, gamma 1 | 0.996 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.996 | |
| Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.994 | |
| Bmp4 | bone morphogenetic protein 4 | 0.992 | |
| Nrp1 | neuropilin 1 | 0.988 | |
| Vegfa | vascular endothelial growth factor A | 0.981 | |
| Plau | plasminogen activator, urokinase | 0.981 | |
| Trp63 | transformation related protein 63 | 0.976 | |
| Pax2 | paired box gene 2 | 0.964 | |
| Arhgef11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.964 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.959 | |
| Lamb1 | laminin B1 | 0.955 | |
| Bmp7 | bone morphogenetic protein 7 | 0.952 | |
| Kdr | kinase insert domain protein receptor | 0.943 | |
| Tcf21 | transcription factor 21 | 0.942 | |
| Sox7 | SRY-box containing gene 7 | 0.937 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.924 | |
| Sema3f | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | 0.898 | |
| Itga3 | integrin alpha 3 | 0.889 | |
| Rarg | retinoic acid receptor, gamma | 0.884 | |
| Hoxa13 | homeobox A13 | 0.864 | |
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.861 | |
| Plxna1 | plexin A1 | 0.852 | |
| Fgf8 | fibroblast growth factor 8 | 0.839 | |
| Hoxd13 | homeobox D13 | 0.824 | |
| Hoxd11 | homeobox D11 | 0.819 | |
| Flt4 | FMS-like tyrosine kinase 4 | 0.816 | |
| Ddr2 | discoidin domain receptor family, member 2 | 0.794 | |
| Epha4 | Eph receptor A4 | 0.772 | |
| Lama5 | laminin, alpha 5 | 0.770 | |
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.759 | |
| Mrc2 | mannose receptor, C type 2 | 0.756 | |
| Tnf | tumor necrosis factor | 0.736 | |
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.701 | |
| Bmp5 | bone morphogenetic protein 5 | 0.701 | |
| Nos1 | nitric oxide synthase 1, neuronal | 0.681 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.669 | |
| Prrx1 | paired related homeobox 1 | 0.666 | |
| Foxc1 | forkhead box C1 | 0.662 | |
| Nid1 | nidogen 1 | 0.641 | |
| Pax3 | paired box gene 3 | 0.621 | |
| Ednra | endothelin receptor type A | 0.610 | |
| Tbx3 | T-box 3 | 0.601 | |
| Lhx1 | LIM homeobox protein 1 | 0.595 | |
| Pthlh | parathyroid hormone-like peptide | 0.591 | |
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.580 | |
| Ar | androgen receptor | 0.567 | |
| Mmp9 | matrix metallopeptidase 9 | 0.550 | |
| Wt1 | Wilms tumor 1 homolog | 0.547 | |
| Npr3 | natriuretic peptide receptor 3 | 0.540 | |
| Flt1 | FMS-like tyrosine kinase 1 | 0.525 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.491 | |
| Tbx2 | T-box 2 | 0.480 | |
| Emp2 | epithelial membrane protein 2 | 0.459 | |
| Tyro3 | TYRO3 protein tyrosine kinase 3 | 0.454 | |
| Fgf10 | fibroblast growth factor 10 | 0.454 | |
| Tbx1 | T-box 1 | 0.440 | |
| She | src homology 2 domain-containing transforming protein E | 0.437 | |
| Il10 | interleukin 10 | 0.437 | |
| Ltbp1 | latent transforming growth factor beta binding protein 1 | 0.423 | |
| Spry4 | sprouty homolog 4 (Drosophila) | 0.422 | |
| Lama1 | laminin, alpha 1 | 0.421 | |
| Lama3 | laminin, alpha 3 | 0.419 | |
| Col4a2 | collagen, type IV, alpha 2 | 0.414 | |
| Cdx1 | caudal type homeobox 1 | 0.413 | |
| Lamc2 | laminin, gamma 2 | 0.404 | |
| Pdgfb | platelet derived growth factor, B polypeptide | 0.404 | |
| Edn3 | endothelin 3 | 0.402 | |
| Pcdh12 | protocadherin 12 | 0.397 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.358 | |
| Grb10 | growth factor receptor bound protein 10 | 0.349 | |
| Ror1 | receptor tyrosine kinase-like orphan receptor 1 | 0.349 | |
| Sema3a | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.345 | |
| Hoxa11 | homeobox A11 | 0.327 | |
| Dmd | dystrophin, muscular dystrophy | 0.324 | |
| Cdh13 | cadherin 13 | 0.309 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.309 | |
| Tbx15 | T-box 15 | 0.308 | |
| Col4a3 | collagen, type IV, alpha 3 | 0.299 | |
| Jag1 | jagged 1 | 0.299 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.283 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.281 | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.280 | |
| Kcne1 | potassium voltage-gated channel, Isk-related subfamily, member 1 | 0.272 | |
| Wnt5a | wingless-related MMTV integration site 5A | 0.263 | |
| Sgcd | sarcoglycan, delta (dystrophin-associated glycoprotein) | 0.262 | |
| En1 | engrailed 1 | 0.259 | |
| Fgfr4 | fibroblast growth factor receptor 4 | 0.255 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.252 | |
| Col12a1 | collagen, type XII, alpha 1 | 0.246 | |
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.246 | |
| Tspan9 | tetraspanin 9 | 0.245 | |
| Ltb | lymphotoxin B | 0.244 | |
| Arhgef12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.232 | |
| Foxn1 | forkhead box N1 | 0.229 | |
| Mmp15 | matrix metallopeptidase 15 | 0.228 | |
| Mertk | c-mer proto-oncogene tyrosine kinase | 0.223 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 1.000 | |
| FGF1 | fibroblast growth factor 1 (acidic) | 1.000 | |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.999 | |
| VEGFA | vascular endothelial growth factor A | 0.999 | |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.999 | |
| PLCG1 | phospholipase C, gamma 1 | 0.980 | |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.978 | |
| FGF10 | fibroblast growth factor 10 | 0.966 | |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.963 | |
| FN1 | fibronectin 1 | 0.947 | |
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.947 | |
| FGF2 | fibroblast growth factor 2 (basic) | 0.933 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.882 | |
| EGFR | epidermal growth factor receptor | 0.865 | |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.821 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.800 | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.768 | |
| PSEN1 | presenilin 1 | 0.743 | |
| RANBP9 | RAN binding protein 9 | 0.690 | |
| UTRN | utrophin | 0.633 | |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.621 | |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.610 | |
| PDGFC | platelet derived growth factor C | 0.556 | |
| THBS1 | thrombospondin 1 | 0.520 | |
| COL4A1 | collagen, type IV, alpha 1 | 0.490 | |
| FGFR1 | fibroblast growth factor receptor 1 | 0.480 | |
| FGF7 | fibroblast growth factor 7 | 0.439 | |
| DMD | dystrophin | 0.404 | |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.402 | |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.400 | |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.368 | |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.364 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.345 | |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.332 | |
| COL6A1 | collagen, type VI, alpha 1 | 0.311 | |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.307 | |
| FGFR2 | fibroblast growth factor receptor 2 | 0.302 | |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.266 | |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.261 | |
| IL6R | interleukin 6 receptor | 0.255 | |
| FGFR3 | fibroblast growth factor receptor 3 | 0.246 | |
| DTNA | dystrobrevin, alpha | 0.231 | |
| COL5A1 | collagen, type V, alpha 1 | 0.216 | |
| NOG | noggin | 0.202 | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.201 | |
| PLAUR | plasminogen activator, urokinase receptor | 0.184 | |
| OSMR | oncostatin M receptor | 0.183 | |
| EPAS1 | endothelial PAS domain protein 1 | 0.172 | |
| NRP1 | neuropilin 1 | 0.169 | |
| COL2A1 | collagen, type II, alpha 1 | 0.167 | |
| COL7A1 | collagen, type VII, alpha 1 | 0.160 | |
| FYN | FYN oncogene related to SRC, FGR, YES | 0.148 | |
| AGRN | agrin | 0.144 | |
| TNC | tenascin C | 0.141 | |
| PLXNB1 | plexin B1 | 0.122 | |
| CTGF | connective tissue growth factor | 0.115 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.115 | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.107 | |
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.103 | |
| PVR | poliovirus receptor | 0.087 | |
| STC1 | stanniocalcin 1 | 0.086 | |
| GAB1 | GRB2-associated binding protein 1 | 0.082 | |
| PGF | placental growth factor | 0.076 | |
| LAT | linker for activation of T cells | 0.073 | |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.073 | |
| KNG1 | kininogen 1 | 0.068 | |
| VEGFC | vascular endothelial growth factor C | 0.067 | |
| BCAM | basal cell adhesion molecule (Lutheran blood group) | 0.062 | |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.057 | |
| JUP | junction plakoglobin | 0.054 | |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.052 | |
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.051 | |
| COL4A2 | collagen, type IV, alpha 2 | 0.051 | |
| NOSTRIN | nitric oxide synthase trafficker | 0.050 | |
| TGFB3 | transforming growth factor, beta 3 | 0.049 | |
| A2M | alpha-2-macroglobulin | 0.048 | |
| SHB | Src homology 2 domain containing adaptor protein B | 0.047 | |
| COL1A1 | collagen, type I, alpha 1 | 0.047 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.047 | |
| TGFB2 | transforming growth factor, beta 2 | 0.046 | |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 0.046 | |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.046 | |
| PXDN | peroxidasin homolog (Drosophila) | 0.046 | |
| NRP2 | neuropilin 2 | 0.045 | |
| C3 | complement component 3 | 0.044 | |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.041 | |
| GPC1 | glypican 1 | 0.039 | |
| GCGR | glucagon receptor | 0.039 | |
| LAMB3 | laminin, beta 3 | 0.036 | |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.035 | |
| LAMA5 | laminin, alpha 5 | 0.034 | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.033 | |
| GHR | growth hormone receptor | 0.033 | |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.033 | |
| NNMT | nicotinamide N-methyltransferase | 0.032 | |
| MDFI | MyoD family inhibitor | 0.031 | |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | 0.030 | |
| JAG1 | jagged 1 | 0.030 | |
| HRH1 | histamine receptor H1 | 0.030 | |
| SERTAD1 | SERTA domain containing 1 | 0.029 |