The network for 'oocyte anterior posterior axis specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

oocyte anterior posterior axis specification

Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster.

Mus musculus
Name Description Probability Func Analog Organism
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1.000
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.999
Ctnnb1 catenin (cadherin associated protein), beta 1 0.997
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.965
Stx1a syntaxin 1A (brain) 0.964
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.952
Snap25 synaptosomal-associated protein 25 0.935
Apc adenomatosis polyposis coli 0.919
Fus fusion, derived from t(12;16) malignant liposarcoma (human) 0.905
Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.903
Htt huntingtin 0.863
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 0.852
Npm1 nucleophosmin 1 0.809
Cct2 chaperonin containing Tcp1, subunit 2 (beta) 0.795
Gsk3b glycogen synthase kinase 3 beta 0.784
Arid1b AT rich interactive domain 1B (SWI-like) 0.780
Cct6a chaperonin containing Tcp1, subunit 6a (zeta) 0.775
Smad4 MAD homolog 4 (Drosophila) 0.738
Vamp2 vesicle-associated membrane protein 2 0.720
Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 0.686
Hspa8 heat shock protein 8 0.660
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.655
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.645
Bicd2 bicaudal D homolog 2 (Drosophila) 0.627
Srsf2 serine/arginine-rich splicing factor 2 0.599
Set SET nuclear oncogene 0.591
Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 0.585
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.579
Bmpr1a bone morphogenetic protein receptor, type 1A 0.579
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.565
Dlg4 discs, large homolog 4 (Drosophila) 0.562
Rac1 RAS-related C3 botulinum substrate 1 0.540
Mtap2 microtubule-associated protein 2 0.536
Ccnd1 cyclin D1 0.535
Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein 0.530
Hnrnpf heterogeneous nuclear ribonucleoprotein F 0.524
Wdr1 WD repeat domain 1 0.510
Vasp vasodilator-stimulated phosphoprotein 0.496
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.493
Ncl nucleolin 0.489
Dlg2 discs, large homolog 2 (Drosophila) 0.486
Cops4 COP9 (constitutive photomorphogenic) homolog, subunit 4 (Arabidopsis thaliana) 0.484
Eif4a1 eukaryotic translation initiation factor 4A1 0.484
Vcp valosin containing protein 0.471
Ptges3 prostaglandin E synthase 3 (cytosolic) 0.466
2500003M10Rik RIKEN cDNA 2500003M10 gene 0.456
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.447
Eif5a eukaryotic translation initiation factor 5A 0.435
Ap2a1 adaptor protein complex AP-2, alpha 1 subunit 0.432
Caprin1 cell cycle associated protein 1 0.430
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.430
Erh enhancer of rudimentary homolog (Drosophila) 0.428
Spnb2 spectrin beta 2 0.418
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.388
Hnrnpk heterogeneous nuclear ribonucleoprotein K 0.371
Pdlim5 PDZ and LIM domain 5 0.369
Cltc clathrin, heavy polypeptide (Hc) 0.345
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.338
Dlg1 discs, large homolog 1 (Drosophila) 0.337
Hif1a hypoxia inducible factor 1, alpha subunit 0.332
Snrpd1 small nuclear ribonucleoprotein D1 0.323
Smad1 MAD homolog 1 (Drosophila) 0.308
Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 0.290
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.290
Hnrnpd heterogeneous nuclear ribonucleoprotein D 0.289
Ccdc64 coiled-coil domain containing 64 0.273
Tsc1 tuberous sclerosis 1 0.263
Ddx3x DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked 0.261
Kpnb1 karyopherin (importin) beta 1 0.256
Rpgrip1l Rpgrip1-like 0.255
Cct7 chaperonin containing Tcp1, subunit 7 (eta) 0.254
Ube2n ubiquitin-conjugating enzyme E2N 0.252
Prkcz protein kinase C, zeta 0.252
Snrpb small nuclear ribonucleoprotein B 0.252
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.251
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.247
Prmt1 protein arginine N-methyltransferase 1 0.243
Shank2 SH3/ankyrin domain gene 2 0.236
Nudc nuclear distribution gene C homolog (Aspergillus) 0.233
Syp synaptophysin 0.231
Bsn bassoon 0.230
Stx12 syntaxin 12 0.226
Capzb capping protein (actin filament) muscle Z-line, beta 0.225
Cul3 cullin 3 0.218
Mael maelstrom homolog (Drosophila) 0.215
G3bp1 Ras-GTPase-activating protein SH3-domain binding protein 1 0.211
Tfdp2 transcription factor Dp 2 0.211
Nf2 neurofibromatosis 2 0.210
Arc activity regulated cytoskeletal-associated protein 0.206
1110004F10Rik RIKEN cDNA 1110004F10 gene 0.205
Prmt5 protein arginine N-methyltransferase 5 0.204
Fbl fibrillarin 0.199
Ewsr1 Ewing sarcoma breakpoint region 1 0.198
Kars lysyl-tRNA synthetase 0.191
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.190
Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 0.187
Pcbp1 poly(rC) binding protein 1 0.186
Nap1l1 nucleosome assembly protein 1-like 1 0.185
Dhx15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 0.183
Ina internexin neuronal intermediate filament protein, alpha 0.183
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
par-5 Protein PAR-5 0.012
glh-1 Protein GLH-1 0.010
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Danio rerio
Name Description Probability Func Analog Organism
nanos3 nanos homolog 3 0.981
ca15b carbonic anhydrase XV b 0.936
piwil2 piwi-like 2 (Drosophila) 0.842
piwil1 piwi-like 1 (Drosophila) 0.763
brca2 breast cancer 2, early onset 0.669
vasa vasa homolog 0.609
elavl2 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) 0.557
org oogenesis-related gene 0.534
dazl daz-like gene 0.506
dlg2 discs, large (Drosophila) homolog 2 0.483
zorba Orb/CPEB-related RNA-binding protein 0.459
dlg1 discs, large (Drosophila) homolog 1 0.398
tdrd1 tudor domain containing 1 0.365
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.363
eef1g eukaryotic translation elongation factor 1 gamma 0.326
eif5a eukaryotic translation initiation factor 5A 0.301
nudt9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.300
buc bucky ball 0.245
rpl3 ribosomal protein L3 0.240
pfn2 profilin 2 0.239
snx6 sorting nexin 6 0.236
rpl23a ribosomal protein L23a 0.235
zgc:103482 zgc:103482 0.222
dnd dead end 0.218
ilf2 interleukin enhancer binding factor 2 0.216
atp6v1h ATPase, H+ transporting, lysosomal, V1 subunit H 0.207
krt8 keratin 8 0.199
zgc:109888 zgc:109888 0.193
cpne1 copine I 0.192
rnf17 ring finger protein 17 0.190
rap1b RAS related protein 1b 0.183
rps4x ribosomal protein S4, X-linked 0.181
pak2a p21 (CDKN1A)-activated kinase 2a 0.181
ef1a elongation factor 1-alpha 0.181
hnrnpa0l heterogeneous nuclear ribonucleoprotein A0, like 0.178
acsbg2 acyl-CoA synthetase bubblegum family member 2 0.171
rpl4 ribosomal protein L4 0.170
sfrs3b splicing factor, arginine/serine-rich 3b 0.170
tubg1 tubulin, gamma 1 0.168
myl1 myosin, light chain 1, alkali; skeletal, fast 0.164
zgc:103697 zgc:103697 0.163
zgc:193933 zgc:193933 0.161
cct7 chaperonin containing TCP1, subunit 7 (eta) 0.161
rps2 ribosomal protein S2 0.159
smarce1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.159
ilk integrin linked kinase 0.157
dynlt3 dynein, light chain, Tctex-type 3 0.157
spsb4a splA/ryanodine receptor domain and SOCS box containing 4a 0.152
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.148
stac3 SH3 and cysteine rich domain 3 0.148
spsb1 splA/ryanodine receptor domain and SOCS box containing 1 0.147
ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.146
arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.143
ppargc1al peroxisome proliferator-activated receptor gamma, coactivator 1 alpha like 0.142
znf711 zinc finger protein 711 0.141
pdcd6ip programmed cell death 6 interacting protein 0.139
mpz myelin protein zero 0.138
eif3c eukaryotic translation initiation factor 3, subunit C 0.138
ck2b casein kinase 2 beta 0.137
tpt1 tumor protein, translationally-controlled 1 0.135
rpl5b ribosomal protein L5b 0.134
pkm2a pyruvate kinase, muscle, a 0.131
rps9 ribosomal protein S9 0.128
flot1b flotillin 1b 0.126
gdf9 growth differentiation factor 9 0.123
hnrnpa0 heterogeneous nuclear ribonucleoprotein A0 0.120
psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.119
prkd1 protein kinase D1 0.118
rps24 ribosomal protein S24 0.118
eif4a1a eukaryotic translation initiation factor 4A, isoform 1A 0.118
esyt3 extended synaptotagmin-like protein 3 0.116
atp1b3b ATPase, Na+/K+ transporting, beta 3b polypeptide 0.115
eif4a1b eukaryotic translation initiation factor 4A, isoform 1B 0.110
stau2 staufen, RNA binding protein, homolog 2 (Drosophila) 0.108
rpl7a ribosomal protein L7a 0.107
tnnc2 troponin C type 2 (fast) 0.107
neb nebulin 0.107
rpl36a ribosomal protein L36A 0.106
LOC561889 granulito 0.106
e2f5 E2F transcription factor 5 0.105
rpl19 ribosomal protein L19 0.100
copeb core promoter element binding protein 0.100
rps10 ribosomal protein S10 0.100
stmn2b stathmin-like 2b 0.099
sf1 splicing factor 1 0.099
chrna1 cholinergic receptor, nicotinic, alpha polypeptide 1 0.098
tdrd7 tudor domain containing 7 0.098
sybu syntabulin (syntaxin-interacting) 0.097
zgc:56005 zgc:56005 0.097
tbpl2 TATA box binding protein like 2 0.096
bactin1 bactin1 0.095
asz1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 0.094
il7r interleukin 7 receptor 0.094
eif3d eukaryotic translation initiation factor 3, subunit D 0.093
eif3b eukaryotic translation initiation factor 3, subunit B 0.092
zgc:65894 zgc:65894 0.091
acvr1b activin A receptor, type IB 0.088
zgc:77155 zgc:77155 0.088
gnao1a guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a 0.088
rpl10 ribosomal protein L10 0.087
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Drosophila melanogaster
Name Description Probability Func Analog Organism
sqd squid 1.000
BicD Bicaudal D 1.000
baz bazooka 1.000
mago mago nashi 0.998
tsu tsunagi 0.998
par-1 CG8201 gene product from transcript CG8201-RA 0.997
osk oskar 0.997
mael maelstrom 0.994
Src64B Src oncogene at 64B 0.992
vas vasa 0.991
slmb supernumerary limbs 0.989
aret arrest 0.988
Hel25E Helicase at 25E 0.985
stau staufen 0.984
aPKC atypical protein kinase C 0.983
spir spire 0.979
CG6854 CG6854 gene product from transcript CG6854-RC 0.978
sec5 CG8843 gene product from transcript CG8843-RA 0.973
pita CG3941 gene product from transcript CG3941-RA 0.967
spn-E spindle E 0.964
Lam Lamin 0.960
par-6 CG5884 gene product from transcript CG5884-RA 0.960
Dhc64C Dynein heavy chain 64C 0.944
tral trailer hitch 0.938
rok Rho-kinase 0.931
Lis-1 Lissencephaly-1 0.924
TER94 CG2331 gene product from transcript CG2331-RA 0.911
shg shotgun 0.903
sqh spaghetti squash 0.903
me31B maternal expression at 31B 0.901
psq pipsqueak 0.897
glo glorund 0.890
Khc Kinesin heavy chain 0.879
egh egghead 0.874
pum pumilio 0.868
Rac1 CG2248 gene product from transcript CG2248-RA 0.862
CG4771 CG4771 gene product from transcript CG4771-RA 0.840
vls valois 0.839
CG11188 CG11188 gene product from transcript CG11188-RA 0.809
Chc Clathrin heavy chain 0.803
Gprk2 G protein-coupled receptor kinase 2 0.801
Dlic Dynein light intermediate chain 0.800
Dcp1 Decapping protein 1 0.793
Cdc42 CG12530 gene product from transcript CG12530-RA 0.790
hts hu li tai shao 0.782
Fmr1 CG6203 gene product from transcript CG6203-RC 0.777
tud tudor 0.739
tho2 CG31671 gene product from transcript CG31671-RA 0.669
orb oo18 RNA-binding protein 0.662
aub aubergine 0.661
cpa capping protein alpha 0.656
Atx2 Ataxin-2 0.636
SRPK CG8174 gene product from transcript CG8174-RA 0.633
ecd ecdysoneless 0.632
ttk tramtrack 0.626
brat brain tumor 0.604
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.540
rhi rhino 0.533
egg eggless 0.514
hb hunchback 0.506
Pen Pendulin 0.501
ens ensconsin 0.500
Rab6 Rab-protein 6 0.486
zuc zucchini 0.476
del deadlock 0.457
CG10260 CG10260 gene product from transcript CG10260-RB 0.456
RpL10Ab Ribosomal protein L10Ab 0.455
Rab5 Rab-protein 5 0.454
krimp krimper 0.443
lic licorne 0.437
sax saxophone 0.430
gus gustavus 0.428
JIL-1 CG6297 gene product from transcript CG6297-RA 0.425
grk gurken 0.404
mtrm matrimony 0.394
bcd bicoid 0.388
spn-A spindle A 0.382
Tm1 Tropomyosin 1 0.376
jagn jagunal 0.368
alpha-Spec alpha Spectrin 0.362
Hrb27C Heterogeneous nuclear ribonucleoprotein at 27C 0.345
kel kelch 0.332
Dp DP transcription factor 0.322
CG17838 CG17838 gene product from transcript CG17838-RA 0.318
cup CG11181 gene product from transcript CG11181-RB 0.315
rin rasputin 0.314
Rab11 Rab-protein 11 0.308
CSN5 COP9 complex homolog subunit 5 0.302
Pi3K21B CG2699 gene product from transcript CG2699-RA 0.292
spn-B spindle B 0.283
tau CG31057 gene product from transcript CG31057-RA 0.282
dap dacapo 0.279
crb crumbs 0.278
qm quemao 0.274
spen split ends 0.271
Sop2 Suppressor of profilin 2 0.270
beta-Spec beta Spectrin 0.265
4EHP CG33100 gene product from transcript CG33100-RA 0.262
armi armitage 0.255
Ets97D Ets at 97D 0.243
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism