The network for 'neuroepithelial cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

neuroepithelial cell differentiation

The process in which epiblast cells acquire specialized features of neuroepithelial cells.

Mus musculus
Name Description Probability Func Analog Organism
Mitf microphthalmia-associated transcription factor 1.000
Shh sonic hedgehog 0.999
Gli3 GLI-Kruppel family member GLI3 0.997
a nonagouti 0.992
Lyst lysosomal trafficking regulator 0.988
Fgf8 fibroblast growth factor 8 0.987
Trp53 transformation related protein 53 0.983
Otx2 orthodenticle homolog 2 (Drosophila) 0.979
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.978
Hps1 Hermansky-Pudlak syndrome 1 homolog (human) 0.959
Fgfr2 fibroblast growth factor receptor 2 0.955
Bmp7 bone morphogenetic protein 7 0.945
Sox2 SRY-box containing gene 2 0.927
Ctnnb1 catenin (cadherin associated protein), beta 1 0.917
Sox9 SRY-box containing gene 9 0.911
Pax3 paired box gene 3 0.907
Pten phosphatase and tensin homolog 0.900
Ednrb endothelin receptor type B 0.897
Fgfr1 fibroblast growth factor receptor 1 0.896
Hand2 heart and neural crest derivatives expressed transcript 2 0.881
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.859
Rarb retinoic acid receptor, beta 0.850
Hand1 heart and neural crest derivatives expressed transcript 1 0.844
Nog noggin 0.843
Bmp4 bone morphogenetic protein 4 0.826
Gli2 GLI-Kruppel family member GLI2 0.822
Wnt3a wingless-related MMTV integration site 3A 0.820
Tyrp1 tyrosinase-related protein 1 0.811
Sox10 SRY-box containing gene 10 0.776
Vegfa vascular endothelial growth factor A 0.771
Hoxa13 homeobox A13 0.758
Tcf4 transcription factor 4 0.751
Foxa2 forkhead box A2 0.748
Ret ret proto-oncogene 0.740
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.722
Kit kit oncogene 0.712
Neurog3 neurogenin 3 0.696
Prrx2 paired related homeobox 2 0.696
Alx4 aristaless-like homeobox 4 0.648
Ptprb protein tyrosine phosphatase, receptor type, B 0.630
Pax6 paired box gene 6 0.630
Pax2 paired box gene 2 0.628
Nkx2-2 NK2 transcription factor related, locus 2 (Drosophila) 0.627
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.620
Wnt10b wingless related MMTV integration site 10b 0.614
Fgfr3 fibroblast growth factor receptor 3 0.601
Sox3 SRY-box containing gene 3 0.588
Tbx2 T-box 2 0.578
Gata6 GATA binding protein 6 0.577
Runx2 runt related transcription factor 2 0.573
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.565
Lhx3 LIM homeobox protein 3 0.557
Hoxd13 homeobox D13 0.553
Gdnf glial cell line derived neurotrophic factor 0.529
Ap3b1 adaptor-related protein complex 3, beta 1 subunit 0.529
Tcf21 transcription factor 21 0.523
Bdkrb2 bradykinin receptor, beta 2 0.522
Pou5f1 POU domain, class 5, transcription factor 1 0.511
Sox7 SRY-box containing gene 7 0.494
Kdr kinase insert domain protein receptor 0.492
Prrx1 paired related homeobox 1 0.490
Cno cappuccino 0.484
Rab27a RAB27A, member RAS oncogene family 0.480
Foxc2 forkhead box C2 0.478
Flt4 FMS-like tyrosine kinase 4 0.477
Gbx2 gastrulation brain homeobox 2 0.464
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.440
Acvr1 activin A receptor, type 1 0.425
Hes1 hairy and enhancer of split 1 (Drosophila) 0.409
Pou3f3 POU domain, class 3, transcription factor 3 0.401
Kitl kit ligand 0.400
Fgf18 fibroblast growth factor 18 0.393
Pitx2 paired-like homeodomain transcription factor 2 0.392
Lhx1 LIM homeobox protein 1 0.362
Zic3 zinc finger protein of the cerebellum 3 0.354
Emx2 empty spiracles homolog 2 (Drosophila) 0.343
Emx1 empty spiracles homolog 1 (Drosophila) 0.341
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.332
Pax8 paired box gene 8 0.322
Isl1 ISL1 transcription factor, LIM/homeodomain 0.321
Eya1 eyes absent 1 homolog (Drosophila) 0.319
Nodal nodal 0.319
Foxc1 forkhead box C1 0.316
Foxf1a forkhead box F1a 0.316
Hps6 Hermansky-Pudlak syndrome 6 0.300
Fgf3 fibroblast growth factor 3 0.298
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.295
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.294
Meox2 mesenchyme homeobox 2 0.285
Gdf5 growth differentiation factor 5 0.272
Nos3 nitric oxide synthase 3, endothelial cell 0.263
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.256
Id1 inhibitor of DNA binding 1 0.251
Bax BCL2-associated X protein 0.246
Wnt4 wingless-related MMTV integration site 4 0.239
Gsc goosecoid homeobox 0.233
Ren1 renin 1 structural 0.232
Rara retinoic acid receptor, alpha 0.232
Rarg retinoic acid receptor, gamma 0.231
Mlph melanophilin 0.230
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
kita kit receptor a 0.997
mitfa microphthalmia-associated transcription factor a 0.975
sox10 SRY-box containing gene 10 0.972
mib mind bomb 0.938
tfap2a transcription factor AP-2 alpha 0.876
foxd3 forkhead box D3 0.874
tyr tyrosinase 0.828
foxi1 forkhead box I1 0.773
msxb muscle segment homeobox B 0.691
slc24a5 solute carrier family 24, member 5 0.648
zgc:112329 zgc:112329 0.634
gdf6a growth differentiation factor 6a 0.615
sc:d812 sc:d812 0.597
rx3 retinal homeobox gene 3 0.566
pmela premelanosome protein a 0.557
prdm1a PR domain containing 1a, with ZNF domain 0.491
hoxb3a homeo box B3a 0.476
sox2 SRY-box containing gene 2 0.435
hlxb9la homeo box HB9 like a 0.425
vps39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.412
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.393
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.377
sox7 SRY-box containing gene 7 0.353
notch1a notch homolog 1a 0.344
slc45a2 solute carrier family 45, member 2 0.335
foxa3 forkhead box A3 0.311
six4b sine oculis homeobox homolog 4b 0.305
pitx2 paired-like homeodomain transcription factor 2 0.277
sox19a SRY-box containing gene 19a 0.276
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.272
gata3 GATA-binding protein 3 0.271
gata2a GATA-binding protein 2a 0.263
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.260
kcnj13 potassium inwardly-rectifying channel, subfamily J, member 13 0.253
tfap2e transcription factor AP-2 epsilon 0.253
hoxd13a homeo box D13a 0.229
dct dopachrome tautomerase 0.227
hhex hematopoietically expressed homeobox 0.217
sox3 SRY-box containing gene 3 0.206
eya1 eyes absent homolog 1 0.196
msxc muscle segment homeobox C 0.190
irx3a iroquois homeobox protein 3a 0.190
six3a sine oculis homeobox homolog 3a 0.177
si:ch211-235f6.2 si:ch211-235f6.2 0.176
sox1a SRY-box containing gene 1a 0.166
tp63 tumor protein p63 0.165
foxg1a forkhead box G1a 0.158
mitfb microphthalmia-associated transcription factor b 0.151
jag1b jagged 1b 0.149
ltk leukocyte tyrosine kinase 0.132
gbx2 gastrulation brain homeo box 2 0.130
otx2 orthodenticle homolog 2 0.125
hmx4 H6 family homeobox 4 0.121
gata6 GATA-binding protein 6 0.120
mab21l2 mab-21-like 2 0.116
crb2a crumbs homolog 2a 0.112
insm1a insulinoma-associated 1a 0.109
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.109
pax2a paired box gene 2a 0.107
spon2a spondin 2a, extracellular matrix protein 0.098
hand2 heart and neural crest derivatives expressed transcript 2 0.093
hoxd10a homeo box D10a 0.093
mlphb melanophilin b 0.093
tyrp1 tyrosinase-related protein 1 0.093
slc4a1b solute carrier family 4, anion exchanger, member 1b 0.091
zgc:162329 zgc:162329 0.091
pax6a paired box gene 6a 0.088
mdkb midkine-related growth factor b 0.088
hlxb9lb homeo box HB9 like b 0.087
bhlhe22 basic helix-loop-helix family, member e22 0.087
hoxa10b homeo box A10b 0.086
tfe3b transcription factor binding to IGHM enhancer 3b 0.084
jag2 jagged 2 0.081
etv2 ets variant gene 2 0.080
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.080
ptch1 patched 1 0.077
tfec transcription factor EC 0.076
cx41.8 connexin 41.8 0.075
csf1ra colony stimulating factor 1 receptor, a 0.075
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.073
flt4 fms-related tyrosine kinase 4 0.072
notch3 notch homolog 3 0.071
foxj1a forkhead box J1a 0.069
tfeb transcription factor EB 0.066
tp53 tumor protein p53 0.066
hoxd11a homeo box D11a 0.065
isl1 islet1 0.064
isl2a islet2a 0.060
zic4 zic family member 4 0.059
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.057
kdrl kinase insert domain receptor like 0.057
dusp5 dual specificity phosphatase 5 0.057
kctd15a potassium channel tetramerisation domain containing 15a 0.055
tbx5a T-box 5a 0.052
tal1 T-cell acute lymphocytic leukemia 1 0.052
pnp4a purine nucleoside phosphorylase 4a 0.051
nkx2.2b NK2 transcription factor related 2b 0.051
mpp5a membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a) 0.050
neurod neurogenic differentiation 0.050
zic6 zic family member 6 0.048
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Drosophila melanogaster
Name Description Probability Func Analog Organism
E(spl) Enhancer of split 0.884
slp1 sloppy paired 1 0.406
HLHmgamma E(spl) region transcript mgamma 0.266
tll tailless 0.250
HLHm7 E(spl) region transcript m7 0.244
HLH54F CG5005 gene product from transcript CG5005-RA 0.225
amos absent MD neurons and olfactory sensilla 0.221
twi twist 0.211
HLHm5 E(spl) region transcript m5 0.204
CG14869 CG14869 gene product from transcript CG14869-RB 0.112
ato atonal 0.104
HLHmdelta E(spl) region transcript mdelta 0.104
bin biniou 0.085
gsb gooseberry 0.077
m4 E(spl) region transcript m4 0.070
pdm2 POU domain protein 2 0.070
hkb huckebein 0.067
unc-5 CG8166 gene product from transcript CG8166-RA 0.067
m2 E(spl) region transcript m2 0.066
sc scute 0.065
ase asense 0.061
tin tinman 0.054
ro rough 0.040
mam mastermind 0.037
mid midline 0.037
HLHmbeta E(spl) region transcript mbeta 0.034
Tom Twin of m4 0.031
malpha E(spl) region transcript malpha 0.030
ac achaete 0.029
byn brachyenteron 0.028
HGTX CG13475 gene product from transcript CG13475-RB 0.026
vav CG7893 gene product from transcript CG7893-RB 0.026
lea leak 0.024
sna snail 0.023
Notum CG13076 gene product from transcript CG13076-RB 0.021
eve even skipped 0.020
Ubx Ultrabithorax 0.019
Msi Male-specific insect derived growth factor 0.019
Kr Kruppel 0.017
l(1)sc lethal of scute 0.017
aop anterior open 0.017
sns sticks and stones 0.017
gcm glial cells missing 0.017
slou slouch 0.015
noc no ocelli 0.015
HLHm3 E(spl) region transcript m3 0.014
stumps CG31317 gene product from transcript CG31317-RC 0.012
pb proboscipedia 0.011
inv invected 0.011
kni knirps 0.011
Doc2 Dorsocross2 0.010
Rel Relish 0.010
pan pangolin 0.010
jeb jelly belly 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
EP300 E1A binding protein p300 0.348
TCF4 transcription factor 4 0.153
TAL1 T-cell acute lymphocytic leukemia 1 0.140
PAX3 paired box 3 0.121
PSEN1 presenilin 1 0.115
RAB27A RAB27A, member RAS oncogene family 0.085
POU5F1 POU class 5 homeobox 1 0.080
FGFR1 fibroblast growth factor receptor 1 0.075
POU3F2 POU class 3 homeobox 2 0.047
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.042
BMPR1A bone morphogenetic protein receptor, type IA 0.042
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.033
HDAC4 histone deacetylase 4 0.032
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.030
SMAD4 SMAD family member 4 0.030
MLPH melanophilin 0.023
RUNX1 runt-related transcription factor 1 0.016
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.013
HDAC2 histone deacetylase 2 0.012
ARRB1 arrestin, beta 1 0.012
KITLG KIT ligand 0.012
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.011
YY1 YY1 transcription factor 0.011
AR androgen receptor 0.011
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.011
TGIF1 TGFB-induced factor homeobox 1 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Adam10 ADAM metallopeptidase domain 10 0.074
Calcrl calcitonin receptor-like 0.030
Lman1 lectin, mannose-binding, 1 0.027
Tgfbr2 transforming growth factor, beta receptor II 0.022
Ednrb endothelin receptor type B 0.021
F13a1 coagulation factor XIII, A1 polypeptide 0.021
RGD1564327 similar to integrin alpha 8 0.019
Nfix nuclear factor I/X (CCAAT-binding transcription factor) 0.018
Ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.018
Aqp4 aquaporin 4 0.017
Lrrc4b leucine rich repeat containing 4B 0.017
Il1r1 interleukin 1 receptor, type I 0.016
Mag myelin-associated glycoprotein 0.015
Tmod2 tropomodulin 2 0.015
Bbx bobby sox homolog (Drosophila) 0.015
Ppap2b phosphatidic acid phosphatase type 2B 0.014
Tcf4 transcription factor 4 0.013
Clic4 chloride intracellular channel 4 0.013
Lbr lamin B receptor 0.013
Nfia nuclear factor I/A 0.013
Rasa1 RAS p21 protein activator (GTPase activating protein) 1 0.012
Rfc1 replication factor C (activator 1) 1 0.011
Igfbp5 insulin-like growth factor binding protein 5 0.011
Olr1654 olfactory receptor 1654 0.011
Hes5 hairy and enhancer of split 5 (Drosophila) 0.011
Myo1c myosin IC 0.011
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.010
Ccdc102a coiled-coil domain containing 102A 0.010
Atf2 activating transcription factor 2 0.010
Kitlg KIT ligand 0.010
A3galt2 alpha 1,3-galactosyltransferase 2 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism