The network for 'pallium development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pallium development

The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.

Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Gli3 GLI-Kruppel family member GLI3 1.000
Pax6 paired box gene 6 1.000
Pax2 paired box gene 2 1.000
Ctnnb1 catenin (cadherin associated protein), beta 1 1.000
Sox2 SRY-box containing gene 2 1.000
Gli2 GLI-Kruppel family member GLI2 1.000
Pax3 paired box gene 3 0.999
Foxc1 forkhead box C1 0.999
Fgfr2 fibroblast growth factor receptor 2 0.999
Emx1 empty spiracles homolog 1 (Drosophila) 0.999
Foxg1 forkhead box G1 0.997
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.995
Dlx5 distal-less homeobox 5 0.995
Msx1 homeobox, msh-like 1 0.994
Hand1 heart and neural crest derivatives expressed transcript 1 0.994
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.993
Tcfap2a transcription factor AP-2, alpha 0.993
Fgfr1 fibroblast growth factor receptor 1 0.990
Hand2 heart and neural crest derivatives expressed transcript 2 0.987
Nog noggin 0.987
Dab1 disabled homolog 1 (Drosophila) 0.985
Rarg retinoic acid receptor, gamma 0.985
Trp53 transformation related protein 53 0.985
Prrx1 paired related homeobox 1 0.984
Eya1 eyes absent 1 homolog (Drosophila) 0.984
Insm1 insulinoma-associated 1 0.983
Sox9 SRY-box containing gene 9 0.982
Emx2 empty spiracles homolog 2 (Drosophila) 0.980
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.979
Foxc2 forkhead box C2 0.978
Fgf10 fibroblast growth factor 10 0.978
Bmp4 bone morphogenetic protein 4 0.978
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.974
Efnb2 ephrin B2 0.973
Col2a1 collagen, type II, alpha 1 0.972
Pbx1 pre B-cell leukemia transcription factor 1 0.967
Lepr leptin receptor 0.967
Lhx1 LIM homeobox protein 1 0.964
Pou3f3 POU domain, class 3, transcription factor 3 0.961
Epha4 Eph receptor A4 0.960
Tgfb2 transforming growth factor, beta 2 0.959
Zeb1 zinc finger E-box binding homeobox 1 0.957
Fgf8 fibroblast growth factor 8 0.956
Nkx2-1 NK2 homeobox 1 0.954
Hoxa1 homeobox A1 0.953
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.953
Trp63 transformation related protein 63 0.952
Msx2 homeobox, msh-like 2 0.951
Neurod1 neurogenic differentiation 1 0.948
Myod1 myogenic differentiation 1 0.945
Ntf3 neurotrophin 3 0.944
Bmp7 bone morphogenetic protein 7 0.944
Hes1 hairy and enhancer of split 1 (Drosophila) 0.941
Pax8 paired box gene 8 0.941
Lmx1a LIM homeobox transcription factor 1 alpha 0.935
Bcl2 B-cell leukemia/lymphoma 2 0.934
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.933
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.933
Ret ret proto-oncogene 0.931
Pitx2 paired-like homeodomain transcription factor 2 0.926
Apc adenomatosis polyposis coli 0.920
Hoxd13 homeobox D13 0.917
Pitx1 paired-like homeodomain transcription factor 1 0.915
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.915
Id1 inhibitor of DNA binding 1 0.914
Chd7 chromodomain helicase DNA binding protein 7 0.913
Pou4f3 POU domain, class 4, transcription factor 3 0.912
Alx4 aristaless-like homeobox 4 0.910
Tbx1 T-box 1 0.899
Tbx3 T-box 3 0.891
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.887
Gdnf glial cell line derived neurotrophic factor 0.883
Sox3 SRY-box containing gene 3 0.880
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.876
Gbx2 gastrulation brain homeobox 2 0.872
Dcc deleted in colorectal carcinoma 0.870
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.866
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.862
En1 engrailed 1 0.854
Nrp1 neuropilin 1 0.852
Pthlh parathyroid hormone-like peptide 0.850
Sox11 SRY-box containing gene 11 0.850
Hoxa2 homeobox A2 0.842
Phox2b paired-like homeobox 2b 0.837
Smad3 MAD homolog 3 (Drosophila) 0.835
Prrx2 paired related homeobox 2 0.833
Gsc goosecoid homeobox 0.832
Hoxd11 homeobox D11 0.816
Chrd chordin 0.813
Notch1 Notch gene homolog 1 (Drosophila) 0.806
Gata4 GATA binding protein 4 0.805
Wnt6 wingless-related MMTV integration site 6 0.804
Rxra retinoid X receptor alpha 0.802
Rarb retinoic acid receptor, beta 0.800
Hoxb1 homeobox B1 0.799
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.796
Bdnf brain derived neurotrophic factor 0.794
Bbs4 Bardet-Biedl syndrome 4 (human) 0.794
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PEX14 peroxisomal biogenesis factor 14 0.752
GSK3B glycogen synthase kinase 3 beta 0.728
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.631
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.485
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.450
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.421
LAMB1 laminin, beta 1 0.413
SORBS3 sorbin and SH3 domain containing 3 0.413
VEGFA vascular endothelial growth factor A 0.364
DLG4 discs, large homolog 4 (Drosophila) 0.354
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.330
PEX19 peroxisomal biogenesis factor 19 0.305
NDEL1 nudE nuclear distribution gene E homolog (A. nidulans)-like 1 0.204
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.184
BAK1 BCL2-antagonist/killer 1 0.180
PEX12 peroxisomal biogenesis factor 12 0.168
AXIN1 axin 1 0.140
BCL2L1 BCL2-like 1 0.139
TCF4 transcription factor 4 0.139
TSC2 tuberous sclerosis 2 0.123
USP46 ubiquitin specific peptidase 46 0.119
E2F1 E2F transcription factor 1 0.108
SCHIP1 schwannomin interacting protein 1 0.107
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.107
PAX3 paired box 3 0.095
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.092
AR androgen receptor 0.087
HNF4A hepatocyte nuclear factor 4, alpha 0.081
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.078
SOX10 SRY (sex determining region Y)-box 10 0.078
PAX6 paired box 6 0.076
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.076
ZHX1 zinc fingers and homeoboxes 1 0.076
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.074
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.072
WDR20 WD repeat domain 20 0.067
SPTBN4 spectrin, beta, non-erythrocytic 4 0.064
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.062
MKL1 megakaryoblastic leukemia (translocation) 1 0.061
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.061
APP amyloid beta (A4) precursor protein 0.060
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.057
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.055
MAP1A microtubule-associated protein 1A 0.048
TP73 tumor protein p73 0.047
SIX3 SIX homeobox 3 0.047
EZR ezrin 0.044
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.043
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.042
KCNA4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.041
RXRA retinoid X receptor, alpha 0.041
UBE3A ubiquitin protein ligase E3A 0.040
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.040
ESR1 estrogen receptor 1 0.038
CPE carboxypeptidase E 0.035
TMEM173 transmembrane protein 173 0.034
GATAD2B GATA zinc finger domain containing 2B 0.033
TP53 tumor protein p53 0.033
APC adenomatous polyposis coli 0.033
SNAPIN SNAP-associated protein 0.032
EPAS1 endothelial PAS domain protein 1 0.029
PAX8 paired box 8 0.029
XIAP X-linked inhibitor of apoptosis 0.029
RPL18A ribosomal protein L18a 0.029
NCOR2 nuclear receptor corepressor 2 0.028
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.028
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.028
PCM1 pericentriolar material 1 0.028
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.027
ASB7 ankyrin repeat and SOCS box containing 7 0.027
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 0.027
SKI v-ski sarcoma viral oncogene homolog (avian) 0.027
QKI quaking homolog, KH domain RNA binding (mouse) 0.026
SCRIB scribbled homolog (Drosophila) 0.026
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.026
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.025
SNX27 sorting nexin family member 27 0.024
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.024
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.023
LHX2 LIM homeobox 2 0.023
BBS2 Bardet-Biedl syndrome 2 0.022
IGF1R insulin-like growth factor 1 receptor 0.022
LIG3 ligase III, DNA, ATP-dependent 0.022
BTRC beta-transducin repeat containing 0.021
PSEN2 presenilin 2 (Alzheimer disease 4) 0.021
RDX radixin 0.021
TTC8 tetratricopeptide repeat domain 8 0.021
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.020
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.019
FLNB filamin B, beta 0.019
YAP1 Yes-associated protein 1 0.019
COL5A2 collagen, type V, alpha 2 0.018
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.018
DCTN1 dynactin 1 0.018
BAI1 brain-specific angiogenesis inhibitor 1 0.017
ALK anaplastic lymphoma receptor tyrosine kinase 0.017
SLIT2 slit homolog 2 (Drosophila) 0.017
PKP4 plakophilin 4 0.017
RTKN rhotekin 0.017
MED25 mediator complex subunit 25 0.017
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Rattus norvegicus
Name Description Probability Func Analog Organism
Anxa2 annexin A2 0.189
Lrrc7 leucine rich repeat containing 7 0.134
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.113
Adra2c adrenergic, alpha-2C-, receptor 0.105
Dlg4 discs, large homolog 4 (Drosophila) 0.097
Dbp D site of albumin promoter (albumin D-box) binding protein 0.093
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.082
Cckbr cholecystokinin B receptor 0.080
Kcnc3 potassium voltage gated channel, Shaw-related subfamily, member 3 0.078
Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.073
Grin3a glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.072
Rorb RAR-related orphan receptor B 0.066
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.059
Akap5 A kinase (PRKA) anchor protein 5 0.056
Ednrb endothelin receptor type B 0.055
Lgals3 lectin, galactoside-binding, soluble, 3 0.054
Tlr4 toll-like receptor 4 0.054
Nkx6-1 NK6 homeobox 1 0.052
Nrxn3 neurexin 3 0.052
Cd40lg CD40 ligand 0.050
Htr5b 5-hydroxytryptamine (serotonin) receptor 5B 0.049
Neurod2 neurogenic differentiation 2 0.047
Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 0.047
Aqp4 aquaporin 4 0.047
Cpb1 carboxypeptidase B1 (tissue) 0.046
Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 0.046
Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 0.046
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.044
Lin7b lin-7 homolog b (C. elegans) 0.043
Il12b interleukin 12B 0.042
Nr4a2 nuclear receptor subfamily 4, group A, member 2 0.042
Casp3 caspase 3 0.042
Glp1r glucagon-like peptide 1 receptor 0.041
Gad2 glutamate decarboxylase 2 0.040
Pou3f3 POU class 3 homeobox 3 0.040
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.039
Pank2 pantothenate kinase 2 (Hallervorden-Spatz syndrome) 0.038
Grik1 glutamate receptor, ionotropic, kainate 1 0.038
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.037
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.037
Gfra2 GDNF family receptor alpha 2 0.036
Znf536 zinc finger protein 536 0.036
Cd9 CD9 molecule 0.035
Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 0.034
Olr1493 olfactory receptor gene Olr1493 0.034
Gria4 glutamate receptor, ionotrophic, AMPA 4 0.034
Pdc phosducin 0.033
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.033
Cmklr1 chemokine-like receptor 1 0.033
Hist1h2ba histone cluster 1, H2ba 0.033
Cryga crystallin, gamma A 0.033
S100a11 S100 calcium binding protein A11 (calizzarin) 0.033
Rup2 urinary protein 2 0.033
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.032
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.031
Unc13a unc-13 homolog A (C. elegans) 0.031
Hoxa2 homeo box A2 0.031
Map2 microtubule-associated protein 2 0.031
Anxa1 annexin A1 0.031
Tnr tenascin R 0.031
Il10ra interleukin 10 receptor, alpha 0.031
Il15 interleukin 15 0.030
Egr3 early growth response 3 0.030
Grm1 glutamate receptor, metabotropic 1 0.030
S100a10 S100 calcium binding protein A10 0.030
Sult1d1 sulfotransferase family 1D, member 1 0.030
Csf1 colony stimulating factor 1 (macrophage) 0.029
Pou2f2 POU class 2 homeobox 2 0.029
Gria2 glutamate receptor, ionotropic, AMPA 2 0.029
Casp12 caspase 12 0.028
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.028
Fgfr2 fibroblast growth factor receptor 2 0.028
Adam17 ADAM metallopeptidase domain 17 0.027
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.027
Trim9 tripartite motif-containing 9 0.027
Bcl2 B-cell CLL/lymphoma 2 0.027
Rims1 regulating synaptic membrane exocytosis 1 0.027
Ahr aryl hydrocarbon receptor 0.027
Ptch1 patched homolog 1 (Drosophila) 0.027
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.026
Ar androgen receptor 0.026
Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 0.026
Camkv CaM kinase-like vesicle-associated 0.026
Lzts1 leucine zipper, putative tumor suppressor 1 0.026
Gria1 glutamate receptor, ionotropic, AMPA 1 0.026
Grid2 glutamate receptor, ionotropic, delta 2 0.026
Slc12a1 solute carrier family 12 (sodium/potassium/chloride transporters), member 1 0.025
Crhbp corticotropin releasing hormone binding protein 0.025
Adam7 ADAM metallopeptidase domain 7 0.025
Unc5a unc-5 homolog A (C. elegans) 0.025
Npy5r neuropeptide Y receptor Y5 0.025
LOC100361547 Cytochrome P450, family 2, subfamily c, polypeptide 7-like 0.025
Calcrl calcitonin receptor-like 0.024
Tgfbr2 transforming growth factor, beta receptor II 0.024
Robo2 roundabout homolog 2 (Drosophila) 0.024
Jak2 Janus kinase 2 0.024
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.024
Znf532 zinc finger protein 532 0.023
Vcsa1 variable coding sequence A1 0.023
LOC246267 resection-induced TPI (rs11) 0.023
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism