The network for 'metencephalon development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

metencephalon development

The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure.

Mus musculus
Name Description Probability Func Analog Organism
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Pax2 paired box gene 2 0.999
Shh sonic hedgehog 0.999
En1 engrailed 1 0.997
Gli2 GLI-Kruppel family member GLI2 0.997
Fgf8 fibroblast growth factor 8 0.995
Trp53 transformation related protein 53 0.993
Gli3 GLI-Kruppel family member GLI3 0.991
Emx1 empty spiracles homolog 1 (Drosophila) 0.991
Pitx2 paired-like homeodomain transcription factor 2 0.988
Insm1 insulinoma-associated 1 0.987
Fgfr1 fibroblast growth factor receptor 1 0.987
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.982
Lmx1b LIM homeobox transcription factor 1 beta 0.980
Pten phosphatase and tensin homolog 0.967
Pax6 paired box gene 6 0.965
Phox2b paired-like homeobox 2b 0.946
Emx2 empty spiracles homolog 2 (Drosophila) 0.944
Tbx3 T-box 3 0.937
Msx2 homeobox, msh-like 2 0.931
Gbx2 gastrulation brain homeobox 2 0.922
Hoxa1 homeobox A1 0.919
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.915
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.913
Sox2 SRY-box containing gene 2 0.907
Msx1 homeobox, msh-like 1 0.898
Kiss1 KiSS-1 metastasis-suppressor 0.874
Neurog2 neurogenin 2 0.873
Reln reelin 0.873
Pax3 paired box gene 3 0.872
Wnt6 wingless-related MMTV integration site 6 0.868
Fgfr2 fibroblast growth factor receptor 2 0.861
Smad4 MAD homolog 4 (Drosophila) 0.860
Eya1 eyes absent 1 homolog (Drosophila) 0.855
Wnt1 wingless-related MMTV integration site 1 0.845
Ank1 ankyrin 1, erythroid 0.840
Abl1 c-abl oncogene 1, non-receptor tyrosine kinase 0.834
Hoxa2 homeobox A2 0.832
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.828
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.812
Dlx5 distal-less homeobox 5 0.810
Bdnf brain derived neurotrophic factor 0.806
Fzd8 frizzled homolog 8 (Drosophila) 0.792
Axin1 axin 1 0.790
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.783
Lmx1a LIM homeobox transcription factor 1 alpha 0.783
Nog noggin 0.781
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.780
Smad3 MAD homolog 3 (Drosophila) 0.779
Dlg4 discs, large homolog 4 (Drosophila) 0.778
Chrd chordin 0.773
Gsc goosecoid homeobox 0.770
Nodal nodal 0.763
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.758
Foxc1 forkhead box C1 0.750
Gdnf glial cell line derived neurotrophic factor 0.747
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.738
Wt1 Wilms tumor 1 homolog 0.735
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.735
Prrx1 paired related homeobox 1 0.733
Otx1 orthodenticle homolog 1 (Drosophila) 0.719
Tbx1 T-box 1 0.715
Isl1 ISL1 transcription factor, LIM/homeodomain 0.711
Drd2 dopamine receptor D2 0.709
Bmp4 bone morphogenetic protein 4 0.705
Ctnnb1 catenin (cadherin associated protein), beta 1 0.705
Lhx5 LIM homeobox protein 5 0.701
Neurog3 neurogenin 3 0.692
C1qc complement component 1, q subcomponent, C chain 0.691
Grid2 glutamate receptor, ionotropic, delta 2 0.684
C1qa complement component 1, q subcomponent, alpha polypeptide 0.678
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.677
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.675
Rarb retinoic acid receptor, beta 0.672
Bcl2 B-cell leukemia/lymphoma 2 0.649
Nkx6-1 NK6 homeobox 1 0.639
Tgfb2 transforming growth factor, beta 2 0.637
Fgf10 fibroblast growth factor 10 0.631
Foxp2 forkhead box P2 0.630
Foxg1 forkhead box G1 0.618
Bmp7 bone morphogenetic protein 7 0.618
Nhlh1 nescient helix loop helix 1 0.611
Fgf15 fibroblast growth factor 15 0.604
Pbx1 pre B-cell leukemia transcription factor 1 0.603
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.601
Wnt3a wingless-related MMTV integration site 3A 0.593
Smo smoothened homolog (Drosophila) 0.579
Rara retinoic acid receptor, alpha 0.575
Lhx1 LIM homeobox protein 1 0.574
Ntf3 neurotrophin 3 0.573
Hoxd3 homeobox D3 0.567
C1qb complement component 1, q subcomponent, beta polypeptide 0.552
Sez6l seizure related 6 homolog like 0.551
Apc adenomatosis polyposis coli 0.541
Pou3f3 POU domain, class 3, transcription factor 3 0.540
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.531
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.530
Ror1 receptor tyrosine kinase-like orphan receptor 1 0.524
Pax8 paired box gene 8 0.521
Rarg retinoic acid receptor, gamma 0.519
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
fgf3 fibroblast growth factor 3 0.968
foxa2 forkhead box A2 0.961
neurod neurogenic differentiation 0.918
wnt1 wingless-type MMTV integration site family, member 1 0.872
phox2a paired-like homeobox 2a 0.857
pax6b paired box gene 6b 0.745
hnf1ba HNF1 homeobox Ba 0.648
wnt2 wingless-type MMTV integration site family member 2 0.643
ascl1a achaete-scute complex-like 1a (Drosophila) 0.616
her5 hairy-related 5 0.551
hmx4 H6 family homeobox 4 0.536
otpb orthopedia homolog b 0.508
egr2b early growth response 2b 0.507
mpz myelin protein zero 0.497
gbx1 gastrulation brain homeobox 1 0.469
atoh1a atonal homolog 1a 0.467
dharma dharma 0.454
dkk1b dickkopf 1b 0.453
wnt4a wingless-type MMTV integration site family, member 4a 0.440
wnt8b wingless-type MMTV integration site family, member 8b 0.422
gbx2 gastrulation brain homeo box 2 0.419
hoxb1b homeo box B1b 0.368
ptf1a pancreas specific transcription factor, 1a 0.347
lhx1a LIM homeobox 1a 0.336
wnt10b wingless-type MMTV integration site family, member 10b 0.323
gli1 GLI-Kruppel family member 1 0.304
dld deltaD 0.303
fzd3a frizzled homolog 3a 0.295
fgf8a fibroblast growth factor 8 a 0.288
cdh2 cadherin 2, neuronal 0.287
tbx1 T-box 1 0.276
dbx1a developing brain homeobox 1a 0.267
ntla no tail a 0.245
ndr2 nodal-related 2 0.242
hoxc4a homeo box C4a 0.242
eng2a engrailed 2a 0.239
dla deltaA 0.236
otx1b orthodenticle homolog 1b 0.231
col4a5 collagen, type IV, alpha 5 (Alport syndrome) 0.228
shha sonic hedgehog a 0.220
tbx16 T-box gene 16 0.209
nadl1.1 neural adhesion molecule L1.1 0.208
sox2 SRY-box containing gene 2 0.207
dlx2a distal-less homeobox gene 2a 0.202
spry2 sprouty homolog 2 0.198
admp anti-dorsalizing morphogenic protein 0.195
lfng lunatic fringe homolog 0.192
neurod4 neurogenic differentiation 4 0.179
sp5l Sp5 transcription factor-like 0.177
nanos3 nanos homolog 3 0.172
chd chordin 0.171
sox32 SRY-box containing gene 32 0.162
pax8 paired box gene 8 0.158
eve1 even-skipped-like1 0.158
zfyve26 zinc finger, FYVE domain containing 26 0.157
zic2a zic family member 2 (odd-paired homolog, Drosophila), a 0.153
neurog1 neurogenin 1 0.153
hoxb1a homeo box B1a 0.150
pitx3 paired-like homeodomain transcription factor 3 0.147
hoxd4a homeo box D4a 0.146
irx7 iroquois homeobox protein 7 0.141
tal1 T-cell acute lymphocytic leukemia 1 0.140
map2k4a mitogen-activated protein kinase kinase 4a 0.140
wnt3 wingless-type MMTV integration site family, member 3 0.134
sox17 SRY-box containing gene 17 0.133
eng2b engrailed 2b 0.131
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.129
nes nestin 0.128
wif1 wnt inhibitory factor 1 0.126
wnt11 wingless-type MMTV integration site family, member 11 0.124
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.123
st8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.120
cdx4 caudal type homeo box transcription factor 4 0.119
gata2a GATA-binding protein 2a 0.118
her8a hairy-related 8a 0.118
isl1 islet1 0.115
foxa1 forkhead box A1 0.113
nkx6.2 NK6 transcription factor related, locus 2 0.110
six3b sine oculis homeobox homolog 3b 0.102
meis3 myeloid ecotropic viral integration site 3 0.102
raraa retinoic acid receptor, alpha a 0.101
fbp1b fructose-1,6-bisphosphatase 1b 0.097
wnt10a wingless-type MMTV integration site family, member 10a 0.096
hmx3 homeo box (H6 family) 3 0.096
crestin crestin 0.094
pou5f1 POU domain, class 5, transcription factor 1 0.092
mnx1 motor neuron and pancreas homeobox 1 0.092
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.092
flh floating head 0.091
nkx2.2a NK2 transcription factor related 2a 0.091
lratb lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b) 0.091
sox19b SRY-box containing gene 19b 0.091
cx30.3 connexin 30.3 0.089
irx3a iroquois homeobox protein 3a 0.087
fgf10a fibroblast growth factor 10a 0.087
olig4 oligodendrocyte transcription factor 4 0.086
gja3 gap junction protein, alpha 3 0.085
bmp2a bone morphogenetic protein 2a 0.085
igf1rb insulin-like growth factor 1b receptor 0.085
dab1b disabled homolog 1b (Drosophila) 0.083
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
HDAC2 histone deacetylase 2 0.975
BCL2L1 BCL2-like 1 0.965
ESR1 estrogen receptor 1 0.963
TRRAP transformation/transcription domain-associated protein 0.912
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.901
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.849
PDZD11 PDZ domain containing 11 0.834
TP53 tumor protein p53 0.833
PPP5C protein phosphatase 5, catalytic subunit 0.736
SKI v-ski sarcoma viral oncogene homolog (avian) 0.535
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.497
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.485
SNTG2 syntrophin, gamma 2 0.477
CHDH choline dehydrogenase 0.476
AR androgen receptor 0.472
LMO4 LIM domain only 4 0.415
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.413
COPB1 coatomer protein complex, subunit beta 1 0.410
ATG13 ATG13 autophagy related 13 homolog (S. cerevisiae) 0.403
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.400
APC adenomatous polyposis coli 0.391
MYOD1 myogenic differentiation 1 0.372
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.348
PTCH1 patched 1 0.346
NRXN1 neurexin 1 0.331
NCOA1 nuclear receptor coactivator 1 0.316
HNF4A hepatocyte nuclear factor 4, alpha 0.312
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.312
SETD8 SET domain containing (lysine methyltransferase) 8 0.304
PDX1 pancreatic and duodenal homeobox 1 0.301
GATA2 GATA binding protein 2 0.299
HOXD12 homeobox D12 0.285
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.282
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.276
SOX1 SRY (sex determining region Y)-box 1 0.260
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.253
NDP Norrie disease (pseudoglioma) 0.245
ZNF512B zinc finger protein 512B 0.236
SESN2 sestrin 2 0.234
HOXA9 homeobox A9 0.227
TCF4 transcription factor 4 0.224
TCF12 transcription factor 12 0.218
RIN1 Ras and Rab interactor 1 0.212
ACTL6B actin-like 6B 0.211
FGF3 fibroblast growth factor 3 0.207
EGFR epidermal growth factor receptor 0.202
ATN1 atrophin 1 0.197
MYO16 myosin XVI 0.187
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.186
RAX retina and anterior neural fold homeobox 0.181
RUNX1 runt-related transcription factor 1 0.181
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.177
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.174
CALCA calcitonin-related polypeptide alpha 0.172
SIX6 SIX homeobox 6 0.166
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.166
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.166
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.160
RPL18A ribosomal protein L18a 0.157
AMBRA1 autophagy/beclin-1 regulator 1 0.150
SEC24D SEC24 family, member D (S. cerevisiae) 0.150
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 0.148
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.147
DDX17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 0.147
NCOR1 nuclear receptor corepressor 1 0.141
TRIP6 thyroid hormone receptor interactor 6 0.139
TADA2A transcriptional adaptor 2A 0.138
TAL1 T-cell acute lymphocytic leukemia 1 0.138
MPDZ multiple PDZ domain protein 0.138
LSAMP limbic system-associated membrane protein 0.137
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.137
BAI1 brain-specific angiogenesis inhibitor 1 0.136
GATA4 GATA binding protein 4 0.135
MET met proto-oncogene (hepatocyte growth factor receptor) 0.134
PBX1 pre-B-cell leukemia homeobox 1 0.131
LPHN1 latrophilin 1 0.128
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.127
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 0.124
WNT3A wingless-type MMTV integration site family, member 3A 0.124
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.124
NEGR1 neuronal growth regulator 1 0.121
POU4F3 POU class 4 homeobox 3 0.121
DLG2 discs, large homolog 2 (Drosophila) 0.121
SEC23A Sec23 homolog A (S. cerevisiae) 0.120
KCNQ2 potassium voltage-gated channel, KQT-like subfamily, member 2 0.118
LHX3 LIM homeobox 3 0.118
SETDB1 SET domain, bifurcated 1 0.117
SEC24A SEC24 family, member A (S. cerevisiae) 0.116
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.113
LRRK2 leucine-rich repeat kinase 2 0.113
NKX6-1 NK6 homeobox 1 0.113
DKK1 dickkopf homolog 1 (Xenopus laevis) 0.111
TP73 tumor protein p73 0.111
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.110
SOX11 SRY (sex determining region Y)-box 11 0.110
ARHGAP22 Rho GTPase activating protein 22 0.106
FOXA2 forkhead box A2 0.105
SRRM4 serine/arginine repetitive matrix 4 0.105
HYOU1 hypoxia up-regulated 1 0.105
CHD3 chromodomain helicase DNA binding protein 3 0.105
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism