The network for 'head morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

head morphogenesis

The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.

Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Pax3 paired box gene 3 0.999
Pitx2 paired-like homeodomain transcription factor 2 0.999
Tbx3 T-box 3 0.998
Otx2 orthodenticle homolog 2 (Drosophila) 0.994
Fgfr2 fibroblast growth factor receptor 2 0.981
Col1a1 collagen, type I, alpha 1 0.975
T brachyury 0.973
Hand1 heart and neural crest derivatives expressed transcript 1 0.964
Hoxa1 homeobox A1 0.948
Gbx2 gastrulation brain homeobox 2 0.941
Fgf8 fibroblast growth factor 8 0.931
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.922
Tbx1 T-box 1 0.918
Neurog2 neurogenin 2 0.907
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.893
Pitx1 paired-like homeodomain transcription factor 1 0.892
Isl1 ISL1 transcription factor, LIM/homeodomain 0.892
Fbn1 fibrillin 1 0.892
Nodal nodal 0.858
Foxc2 forkhead box C2 0.858
Meox2 mesenchyme homeobox 2 0.856
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.847
Msx1 homeobox, msh-like 1 0.840
Gli3 GLI-Kruppel family member GLI3 0.840
Zeb1 zinc finger E-box binding homeobox 1 0.834
Msx2 homeobox, msh-like 2 0.825
Schip1 schwannomin interacting protein 1 0.795
Tal1 T-cell acute lymphocytic leukemia 1 0.793
Fgfr1 fibroblast growth factor receptor 1 0.784
Twist2 twist homolog 2 (Drosophila) 0.774
Vegfa vascular endothelial growth factor A 0.755
Tiparp TCDD-inducible poly(ADP-ribose) polymerase 0.753
Pax6 paired box gene 6 0.749
Lef1 lymphoid enhancer binding factor 1 0.749
Hand2 heart and neural crest derivatives expressed transcript 2 0.735
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.677
Tcfap2a transcription factor AP-2, alpha 0.670
Fgf10 fibroblast growth factor 10 0.664
Arid5b AT rich interactive domain 5B (MRF1-like) 0.652
Snai1 snail homolog 1 (Drosophila) 0.641
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.638
Sox11 SRY-box containing gene 11 0.634
Neurod1 neurogenic differentiation 1 0.630
Alx4 aristaless-like homeobox 4 0.629
Wnt3a wingless-related MMTV integration site 3A 0.624
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.609
Bmp4 bone morphogenetic protein 4 0.603
Col13a1 collagen, type XIII, alpha 1 0.598
Lhx1 LIM homeobox protein 1 0.592
Col2a1 collagen, type II, alpha 1 0.545
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.528
Sox2 SRY-box containing gene 2 0.517
Ptf1a pancreas specific transcription factor, 1a 0.509
Col1a2 collagen, type I, alpha 2 0.496
Nos3 nitric oxide synthase 3, endothelial cell 0.495
Dlx1 distal-less homeobox 1 0.493
Pax9 paired box gene 9 0.483
Col5a1 collagen, type V, alpha 1 0.470
Gli2 GLI-Kruppel family member GLI2 0.466
Zic3 zinc finger protein of the cerebellum 3 0.462
Gata4 GATA binding protein 4 0.462
Chd7 chromodomain helicase DNA binding protein 7 0.459
Csf1 colony stimulating factor 1 (macrophage) 0.443
Sgpl1 sphingosine phosphate lyase 1 0.441
Dlx5 distal-less homeobox 5 0.433
Col6a2 collagen, type VI, alpha 2 0.413
Pax2 paired box gene 2 0.412
Gdnf glial cell line derived neurotrophic factor 0.406
Col3a1 collagen, type III, alpha 1 0.405
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.405
Sox9 SRY-box containing gene 9 0.403
Tlx3 T-cell leukemia, homeobox 3 0.368
Hoxa11 homeobox A11 0.365
Foxg1 forkhead box G1 0.336
Eln elastin 0.330
Foxc1 forkhead box C1 0.324
Bcl2 B-cell leukemia/lymphoma 2 0.323
Bgn biglycan 0.320
Wt1 Wilms tumor 1 homolog 0.312
Tgfb2 transforming growth factor, beta 2 0.309
Twist1 twist homolog 1 (Drosophila) 0.308
Lmx1a LIM homeobox transcription factor 1 alpha 0.301
Gata1 GATA binding protein 1 0.294
Prrx2 paired related homeobox 2 0.292
Eya1 eyes absent 1 homolog (Drosophila) 0.291
Hoxa13 homeobox A13 0.290
Cdx2 caudal type homeobox 2 0.288
Plekha1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.281
Pou4f2 POU domain, class 4, transcription factor 2 0.269
Hoxb1 homeobox B1 0.269
Acan aggrecan 0.266
Shox2 short stature homeobox 2 0.251
Pax1 paired box gene 1 0.251
Bmp7 bone morphogenetic protein 7 0.249
Gata3 GATA binding protein 3 0.244
Plin1 perilipin 1 0.240
Hoxd11 homeobox D11 0.237
Mecom MDS1 and EVI1 complex locus 0.236
Vangl2 vang-like 2 (van gogh, Drosophila) 0.235
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
bmp4 bone morphogenetic protein 4 0.889
jag1b jagged 1b 0.796
dla deltaA 0.766
col1a2 collagen, type I, alpha 2 0.562
tbx2b T-box 2b 0.447
bmp2b bone morphogenetic protein 2b 0.337
notch3 notch homolog 3 0.322
eya1 eyes absent homolog 1 0.299
dlx3b distal-less homeobox gene 3b 0.277
csnk1a1 casein kinase 1, alpha 1 0.236
wnt5b wingless-type MMTV integration site family, member 5b 0.231
tbx1 T-box 1 0.204
tp63 tumor protein p63 0.184
pitx3 paired-like homeodomain transcription factor 3 0.170
sox9a SRY-box containing gene 9a 0.170
dld deltaD 0.169
dlb deltaB 0.108
shha sonic hedgehog a 0.107
ascl1a achaete-scute complex-like 1a (Drosophila) 0.103
fgf20a fibroblast growth factor 20a 0.095
nkx3.2 NK3 homeobox 2 0.093
fgf10a fibroblast growth factor 10a 0.089
pitx2 paired-like homeodomain transcription factor 2 0.084
rest RE1-silencing transcription factor 0.078
postn periostin, osteoblast specific factor 0.073
unc5b unc-5 homolog B (C. elegans) 0.069
gata3 GATA-binding protein 3 0.064
foxi1 forkhead box I1 0.062
tbx22 T-box 22 0.062
robo3 roundabout homolog 3 0.059
pou1f1 POU domain, class 1, transcription factor 1 0.056
dlc deltaC 0.055
tcf12 transcription factor 12 0.052
barx1 BarH-like homeobox 1 0.047
edn1 endothelin 1 0.044
plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.036
unc45a unc-45 homolog A (C. elegans) 0.033
fgf3 fibroblast growth factor 3 0.033
cdh2 cadherin 2, neuronal 0.033
tgfb3 transforming growth factor, beta 3 0.033
fzd7a frizzled homolog 7a 0.032
ptch2 patched 2 0.031
tbx5a T-box 5a 0.031
prdm1a PR domain containing 1a, with ZNF domain 0.031
gata2a GATA-binding protein 2a 0.030
mab21l2 mab-21-like 2 0.029
prl prolactin 0.028
boc brother of CDO 0.027
ahr2 aryl hydrocarbon receptor 2 0.027
midn midnolin 0.027
pea3 ETS-domain transcription factor pea3 0.026
cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 0.025
yap1 Yes-associated protein 1 0.025
hoxb1b homeo box B1b 0.025
col5a1 procollagen, type V, alpha 1 0.025
rerea arginine-glutamic acid dipeptide (RE) repeats a 0.025
ier5l immediate early response 5-like 0.023
dlx4a distal-less homeobox gene 4a 0.023
col19a1 collagen, type XIX, alpha 1 0.022
fzd9b frizzled homolog 9b 0.022
dlx4b distal-less homeobox gene 4b 0.021
znf503 zinc finger protein 503 0.020
gli2a GLI-Kruppel family member GLI2a 0.020
hand2 heart and neural crest derivatives expressed transcript 2 0.019
insm1b insulinoma-associated 1b 0.019
col12a1 collagen, type XII, alpha 1 0.019
notch1a notch homolog 1a 0.019
snai1a snail homolog 1a (Drosophila) 0.019
neurog1 neurogenin 1 0.018
six1b sine oculis homeobox homolog 1b 0.018
nfatc1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.018
wnt11r wingless-type MMTV integration site family, member 11, related 0.018
cdon cell adhesion molecule-related/down-regulated by oncogenes 0.018
ptch1 patched 1 0.017
fn1 fibronectin 1 0.017
emilin1b elastin microfibril interfacer 1b 0.017
sulf1 sulfatase 1 0.017
flncb filamin C, gamma b (actin binding protein 280) 0.016
cdkn1c cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.016
vcana versican a 0.016
foxe3 forkhead box E3 0.016
alcama activated leukocyte cell adhesion molecule a 0.015
btg1 B-cell translocation gene 1 0.015
hoxa2b homeo box A2b 0.015
traf4a tnf receptor-associated factor 4a 0.015
neo1 neogenin 1 0.015
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.015
evx1 even-skipped homeobox 1 0.015
wif1 wnt inhibitory factor 1 0.015
lama5 laminin, alpha 5 0.014
smad7 MAD, mothers against decapentaplegic homolog 7 (Drosophila) 0.014
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.014
isl1 islet1 0.013
ephb4b eph receptor B4b 0.013
plod1a procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a 0.013
pcdh18a protocadherin 18a 0.013
spry4 sprouty (Drosophila) homolog 4 0.012
s1pr1 sphingosine-1-phosphate receptor 1 0.012
npnt nephronectin 0.012
mmp15b matrix metallopeptidase 15b 0.012
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.024
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.018
NOTCH1 notch 1 0.010
MMS22L MMS22-like, DNA repair protein 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism