The network for 'positive regulation of cardiac muscle tissue growth' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cardiac muscle tissue growth

Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth.

Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Pax2 paired box gene 2 1.000
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 1.000
Fgf8 fibroblast growth factor 8 1.000
Tbx3 T-box 3 1.000
Tbx1 T-box 1 0.997
Foxc1 forkhead box C1 0.996
Notch1 Notch gene homolog 1 (Drosophila) 0.996
Pitx2 paired-like homeodomain transcription factor 2 0.995
Jag1 jagged 1 0.995
Hand2 heart and neural crest derivatives expressed transcript 2 0.992
Gata4 GATA binding protein 4 0.990
Ntf3 neurotrophin 3 0.988
Hoxa1 homeobox A1 0.988
Efnb2 ephrin B2 0.987
Pax3 paired box gene 3 0.975
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.975
Gli3 GLI-Kruppel family member GLI3 0.975
Zfpm2 zinc finger protein, multitype 2 0.951
Bmp4 bone morphogenetic protein 4 0.951
Wt1 Wilms tumor 1 homolog 0.931
Hoxa13 homeobox A13 0.924
Rxra retinoid X receptor alpha 0.918
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.900
Lhx1 LIM homeobox protein 1 0.880
Gata6 GATA binding protein 6 0.879
Nodal nodal 0.865
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.863
Notch2 Notch gene homolog 2 (Drosophila) 0.856
Ret ret proto-oncogene 0.855
Lmx1a LIM homeobox transcription factor 1 alpha 0.854
Tbx2 T-box 2 0.792
Tcf21 transcription factor 21 0.786
Pitx1 paired-like homeodomain transcription factor 1 0.781
Nos3 nitric oxide synthase 3, endothelial cell 0.775
Fgfr1 fibroblast growth factor receptor 1 0.750
Hand1 heart and neural crest derivatives expressed transcript 1 0.744
Fgf10 fibroblast growth factor 10 0.742
Hoxa11 homeobox A11 0.730
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.721
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.720
Hoxd11 homeobox D11 0.696
Chd7 chromodomain helicase DNA binding protein 7 0.690
Sox9 SRY-box containing gene 9 0.671
Foxc2 forkhead box C2 0.624
Isl1 ISL1 transcription factor, LIM/homeodomain 0.612
Nog noggin 0.610
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.575
Wnt10b wingless related MMTV integration site 10b 0.562
Smad6 MAD homolog 6 (Drosophila) 0.547
Dll1 delta-like 1 (Drosophila) 0.547
Bdnf brain derived neurotrophic factor 0.516
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.498
Gja3 gap junction protein, alpha 3 0.480
Dll4 delta-like 4 (Drosophila) 0.480
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.474
Fgf3 fibroblast growth factor 3 0.474
Col13a1 collagen, type XIII, alpha 1 0.459
Ctnnb1 catenin (cadherin associated protein), beta 1 0.458
Gbx2 gastrulation brain homeobox 2 0.452
Vegfa vascular endothelial growth factor A 0.450
Wnt3a wingless-related MMTV integration site 3A 0.421
Meox2 mesenchyme homeobox 2 0.415
Trp63 transformation related protein 63 0.405
Tbx5 T-box 5 0.399
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.362
Chrd chordin 0.359
Sox7 SRY-box containing gene 7 0.353
Pax8 paired box gene 8 0.353
Fgf18 fibroblast growth factor 18 0.337
Msx2 homeobox, msh-like 2 0.320
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.314
Pten phosphatase and tensin homolog 0.304
Mef2c myocyte enhancer factor 2C 0.302
Gata3 GATA binding protein 3 0.295
Foxf1a forkhead box F1a 0.292
Lef1 lymphoid enhancer binding factor 1 0.288
Twist2 twist homolog 2 (Drosophila) 0.283
Gli2 GLI-Kruppel family member GLI2 0.268
Rarg retinoic acid receptor, gamma 0.249
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.247
Gdnf glial cell line derived neurotrophic factor 0.243
Bcl2 B-cell leukemia/lymphoma 2 0.237
Otx1 orthodenticle homolog 1 (Drosophila) 0.229
Lama5 laminin, alpha 5 0.228
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.206
She src homology 2 domain-containing transforming protein E 0.200
Gli1 GLI-Kruppel family member GLI1 0.199
Tbx15 T-box 15 0.186
Otx2 orthodenticle homolog 2 (Drosophila) 0.182
Hmx3 H6 homeobox 3 0.173
Foxn1 forkhead box N1 0.173
Fgf15 fibroblast growth factor 15 0.173
Hoxd13 homeobox D13 0.170
Bmp5 bone morphogenetic protein 5 0.169
Hey1 hairy/enhancer-of-split related with YRPW motif 1 0.169
Ar androgen receptor 0.163
Apc adenomatosis polyposis coli 0.163
Tgfb2 transforming growth factor, beta 2 0.161
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
FGFR2 fibroblast growth factor receptor 2 1.000
FGF1 fibroblast growth factor 1 (acidic) 1.000
CDK2 cyclin-dependent kinase 2 1.000
FGFR1 fibroblast growth factor receptor 1 0.981
FGF10 fibroblast growth factor 10 0.976
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.951
FGF2 fibroblast growth factor 2 (basic) 0.749
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.749
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.705
NOTCH1 notch 1 0.651
JAG1 jagged 1 0.618
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.491
MAML1 mastermind-like 1 (Drosophila) 0.351
FGF7 fibroblast growth factor 7 0.329
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.231
FRS2 fibroblast growth factor receptor substrate 2 0.212
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.180
FGFR3 fibroblast growth factor receptor 3 0.173
NOTCH3 notch 3 0.154
HDAC4 histone deacetylase 4 0.141
SPEN spen homolog, transcriptional regulator (Drosophila) 0.131
CKS2 CDC28 protein kinase regulatory subunit 2 0.127
EP300 E1A binding protein p300 0.118
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.116
ATXN1L ataxin 1-like 0.102
CREBBP CREB binding protein 0.072
NCOA2 nuclear receptor coactivator 2 0.063
CCNB2 cyclin B2 0.058
KAT2B K(lysine) acetyltransferase 2B 0.054
MEF2A myocyte enhancer factor 2A 0.047
PLCG1 phospholipase C, gamma 1 0.045
XIAP X-linked inhibitor of apoptosis 0.044
HDAC9 histone deacetylase 9 0.043
TRO trophinin 0.043
KLF13 Kruppel-like factor 13 0.042
DLG2 discs, large homolog 2 (Drosophila) 0.034
SNW1 SNW domain containing 1 0.029
NCOR2 nuclear receptor corepressor 2 0.029
CTGF connective tissue growth factor 0.027
CIR1 corepressor interacting with RBPJ, 1 0.027
DLL1 delta-like 1 (Drosophila) 0.025
CCNA2 cyclin A2 0.024
NCOA1 nuclear receptor coactivator 1 0.024
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.024
CDK1 cyclin-dependent kinase 1 0.024
KANK2 KN motif and ankyrin repeat domains 2 0.021
GAB2 GRB2-associated binding protein 2 0.021
DLG3 discs, large homolog 3 (Drosophila) 0.020
JAG2 jagged 2 0.020
NOSTRIN nitric oxide synthase trafficker 0.020
NOTCH2 notch 2 0.019
ZEB2 zinc finger E-box binding homeobox 2 0.019
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.018
CCNE1 cyclin E1 0.017
CTNNBL1 catenin, beta like 1 0.016
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.016
FANCE Fanconi anemia, complementation group E 0.015
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 0.015
DDR2 discoidin domain receptor tyrosine kinase 2 0.014
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.014
CELF2 CUGBP, Elav-like family member 2 0.013
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.013
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.013
AR androgen receptor 0.013
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.013
FGF8 fibroblast growth factor 8 (androgen-induced) 0.012
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.012
CKS1B CDC28 protein kinase regulatory subunit 1B 0.012
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.011
DIABLO diablo, IAP-binding mitochondrial protein 0.011
HTT huntingtin 0.011
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.011
TMF1 TATA element modulatory factor 1 0.011
KAL1 Kallmann syndrome 1 sequence 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Acat3 acetyl-Coenzyme A acetyltransferase 3 0.131
Top2a topoisomerase (DNA) II alpha 0.074
Fgfr2 fibroblast growth factor receptor 2 0.066
Musk muscle, skeletal, receptor tyrosine kinase 0.052
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.040
Crhbp corticotropin releasing hormone binding protein 0.037
Gja3 gap junction protein, alpha 3 0.033
Kitlg KIT ligand 0.030
Cdh6 cadherin 6 0.030
Synpo synaptopodin 0.030
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.029
Fdft1 farnesyl diphosphate farnesyl transferase 1 0.026
Grm7 glutamate receptor, metabotropic 7 0.026
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.024
Ccnb1 cyclin B1 0.023
Met met proto-oncogene 0.022
Cyp51 cytochrome P450, family 51 0.022
Ccdc124 coiled-coil domain containing 124 0.021
Prl8a2 prolactin family 8, subfamily a, member 2 0.021
Syt8 synaptotagmin VIII 0.020
Racgap1 Rac GTPase-activating protein 1 0.020
Fgf5 fibroblast growth factor 5 0.020
Pex5l peroxisomal biogenesis factor 5-like 0.020
Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 0.019
Phkg1 phosphorylase kinase, gamma 1 0.019
Otx1 orthodenticle homeobox 1 0.018
Fcer2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.018
Tacr2 tachykinin receptor 2 0.018
Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) 0.018
Kifc1 kinesin family member C1 0.017
RGD1309821 similar to KIAA1161 protein 0.017
Mdga1 MAM domain containing glycosylphosphatidylinositol anchor 1 0.017
Prrx1 paired related homeobox 1 0.017
Syt9 synaptotagmin IX 0.016
Foxi2 forkhead box I2 0.015
Necab1 N-terminal EF-hand calcium binding protein 1 0.015
Sc4mol sterol-C4-methyl oxidase-like 0.015
Chrm4 cholinergic receptor, muscarinic 4 0.015
Cdk1 cyclin-dependent kinase 1 0.014
Ica1l islet cell autoantigen 1-like 0.014
Shox2 short stature homeobox 2 0.014
Ube2c ubiquitin-conjugating enzyme E2C 0.014
RGD1564664 similar to LOC387763 protein 0.014
Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 0.013
Myt1l myelin transcription factor 1-like 0.013
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.013
Svs1 seminal vesicle secretory protein 1 0.013
Npffr1 neuropeptide FF receptor 1 0.013
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.012
Gpr61 G protein-coupled receptor 61 0.012
Egr3 early growth response 3 0.012
Kcnab1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 0.012
Htr2a 5-hydroxytryptamine (serotonin) receptor 2A 0.012
Clstn3 calsyntenin 3 0.012
Pdc phosducin 0.012
A2bp1 ataxin 2 binding protein 1 0.012
Il2ra interleukin 2 receptor, alpha 0.011
Edn1 endothelin 1 0.011
Plxna3 plexin A3 0.011
Oprd1 opioid receptor, delta 1 0.011
Glg1 golgi apparatus protein 1 0.011
Kcnh7 potassium voltage-gated channel, subfamily H (eag-related), member 7 0.011
Dmd dystrophin 0.011
Otud1 OTU domain containing 1 0.011
Nrg1 neuregulin 1 0.011
Cdca3 cell division cycle associated 3 0.011
Unc5b unc-5 homolog B (C. elegans) 0.011
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.011
Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 0.010
Ier5 immediate early response 5 0.010
Cd8b CD8b molecule 0.010
Sycn syncollin 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism