The network for 'wnt signaling pathway involved in forebrain neuroblast division' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

wnt signaling pathway involved in forebrain neuroblast division

The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.

Name Description Probability Func Analog Organism
Gli3 GLI-Kruppel family member GLI3 1.000
Shh sonic hedgehog 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Fgf8 fibroblast growth factor 8 1.000
Pax2 paired box gene 2 1.000
Fgfr1 fibroblast growth factor receptor 1 1.000
Rarg retinoic acid receptor, gamma 1.000
Bmp7 bone morphogenetic protein 7 1.000
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Foxc1 forkhead box C1 1.000
Smo smoothened homolog (Drosophila) 1.000
Bmp4 bone morphogenetic protein 4 1.000
Msx1 homeobox, msh-like 1 0.999
Tbx1 T-box 1 0.999
Ctnnb1 catenin (cadherin associated protein), beta 1 0.999
Lhx1 LIM homeobox protein 1 0.999
Foxc2 forkhead box C2 0.999
Gli2 GLI-Kruppel family member GLI2 0.998
Pax3 paired box gene 3 0.998
Wnt3a wingless-related MMTV integration site 3A 0.998
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.997
T brachyury 0.997
Sox9 SRY-box containing gene 9 0.996
Dlx5 distal-less homeobox 5 0.996
Chrd chordin 0.995
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.995
Otx1 orthodenticle homolog 1 (Drosophila) 0.995
Pitx2 paired-like homeodomain transcription factor 2 0.993
Prrx1 paired related homeobox 1 0.989
Emx2 empty spiracles homolog 2 (Drosophila) 0.988
Tbx3 T-box 3 0.986
Prrx2 paired related homeobox 2 0.986
Rarb retinoic acid receptor, beta 0.984
Nog noggin 0.983
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.978
Lmx1b LIM homeobox transcription factor 1 beta 0.975
Fgfr3 fibroblast growth factor receptor 3 0.971
Gbx2 gastrulation brain homeobox 2 0.969
Msx2 homeobox, msh-like 2 0.964
Pax8 paired box gene 8 0.963
Ptk7 PTK7 protein tyrosine kinase 7 0.962
Hoxa2 homeobox A2 0.959
Gdnf glial cell line derived neurotrophic factor 0.955
Tcfap2a transcription factor AP-2, alpha 0.946
En1 engrailed 1 0.941
Lmx1a LIM homeobox transcription factor 1 alpha 0.939
Fgf10 fibroblast growth factor 10 0.939
Hoxa1 homeobox A1 0.935
Hand1 heart and neural crest derivatives expressed transcript 1 0.919
Rara retinoic acid receptor, alpha 0.916
Wnt1 wingless-related MMTV integration site 1 0.907
Lef1 lymphoid enhancer binding factor 1 0.894
Twist2 twist homolog 2 (Drosophila) 0.891
Hoxd11 homeobox D11 0.879
Tbx2 T-box 2 0.875
Alx4 aristaless-like homeobox 4 0.865
Wnt4 wingless-related MMTV integration site 4 0.864
Eya1 eyes absent 1 homolog (Drosophila) 0.846
Gsc goosecoid homeobox 0.844
Kl klotho 0.836
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.829
Tgfb2 transforming growth factor, beta 2 0.805
Fgf3 fibroblast growth factor 3 0.798
Hoxa13 homeobox A13 0.791
Col2a1 collagen, type II, alpha 1 0.790
Emx1 empty spiracles homolog 1 (Drosophila) 0.776
Ptch1 patched homolog 1 0.769
Vangl2 vang-like 2 (van gogh, Drosophila) 0.750
Hand2 heart and neural crest derivatives expressed transcript 2 0.749
Lrp6 low density lipoprotein receptor-related protein 6 0.745
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.742
Nodal nodal 0.738
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.727
Rxra retinoid X receptor alpha 0.721
Meox2 mesenchyme homeobox 2 0.719
Fgf18 fibroblast growth factor 18 0.713
Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.704
Hoxd13 homeobox D13 0.698
Smad6 MAD homolog 6 (Drosophila) 0.686
Tbx15 T-box 15 0.663
Zeb1 zinc finger E-box binding homeobox 1 0.662
Pou3f3 POU domain, class 3, transcription factor 3 0.659
Trp63 transformation related protein 63 0.647
Sox11 SRY-box containing gene 11 0.637
Pitx1 paired-like homeodomain transcription factor 1 0.630
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.627
Bmper BMP-binding endothelial regulator 0.627
Hoxa11 homeobox A11 0.625
Fzd8 frizzled homolog 8 (Drosophila) 0.607
Hoxa4 homeobox A4 0.602
Tead3 TEA domain family member 3 0.600
Pax9 paired box gene 9 0.586
Pax1 paired box gene 1 0.586
Hoxa3 homeobox A3 0.565
Bmp2 bone morphogenetic protein 2 0.564
Hmx3 H6 homeobox 3 0.552
Col13a1 collagen, type XIII, alpha 1 0.540
Pax6 paired box gene 6 0.536
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.530
Psen1 presenilin 1 0.521
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism