Process View
The network for 'wnt signaling pathway involved in forebrain neuroblast division' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Gli3 | GLI-Kruppel family member GLI3 | 1.000 | |
| Shh | sonic hedgehog | 1.000 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
| Fgf8 | fibroblast growth factor 8 | 1.000 | |
| Pax2 | paired box gene 2 | 1.000 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 1.000 | |
| Rarg | retinoic acid receptor, gamma | 1.000 | |
| Bmp7 | bone morphogenetic protein 7 | 1.000 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 1.000 | |
| Foxc1 | forkhead box C1 | 1.000 | |
| Smo | smoothened homolog (Drosophila) | 1.000 | |
| Bmp4 | bone morphogenetic protein 4 | 1.000 | |
| Msx1 | homeobox, msh-like 1 | 0.999 | |
| Tbx1 | T-box 1 | 0.999 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.999 | |
| Lhx1 | LIM homeobox protein 1 | 0.999 | |
| Foxc2 | forkhead box C2 | 0.999 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.998 | |
| Pax3 | paired box gene 3 | 0.998 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.998 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.997 | |
| T | brachyury | 0.997 | |
| Sox9 | SRY-box containing gene 9 | 0.996 | |
| Dlx5 | distal-less homeobox 5 | 0.996 | |
| Chrd | chordin | 0.995 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.995 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.995 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.993 | |
| Prrx1 | paired related homeobox 1 | 0.989 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.988 | |
| Tbx3 | T-box 3 | 0.986 | |
| Prrx2 | paired related homeobox 2 | 0.986 | |
| Rarb | retinoic acid receptor, beta | 0.984 | |
| Nog | noggin | 0.983 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.978 | |
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.975 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.971 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.969 | |
| Msx2 | homeobox, msh-like 2 | 0.964 | |
| Pax8 | paired box gene 8 | 0.963 | |
| Ptk7 | PTK7 protein tyrosine kinase 7 | 0.962 | |
| Hoxa2 | homeobox A2 | 0.959 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.955 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.946 | |
| En1 | engrailed 1 | 0.941 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.939 | |
| Fgf10 | fibroblast growth factor 10 | 0.939 | |
| Hoxa1 | homeobox A1 | 0.935 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.919 | |
| Rara | retinoic acid receptor, alpha | 0.916 | |
| Wnt1 | wingless-related MMTV integration site 1 | 0.907 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.894 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.891 | |
| Hoxd11 | homeobox D11 | 0.879 | |
| Tbx2 | T-box 2 | 0.875 | |
| Alx4 | aristaless-like homeobox 4 | 0.865 | |
| Wnt4 | wingless-related MMTV integration site 4 | 0.864 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.846 | |
| Gsc | goosecoid homeobox | 0.844 | |
| Kl | klotho | 0.836 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.829 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.805 | |
| Fgf3 | fibroblast growth factor 3 | 0.798 | |
| Hoxa13 | homeobox A13 | 0.791 | |
| Col2a1 | collagen, type II, alpha 1 | 0.790 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.776 | |
| Ptch1 | patched homolog 1 | 0.769 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.750 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.749 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.745 | |
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.742 | |
| Nodal | nodal | 0.738 | |
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.727 | |
| Rxra | retinoid X receptor alpha | 0.721 | |
| Meox2 | mesenchyme homeobox 2 | 0.719 | |
| Fgf18 | fibroblast growth factor 18 | 0.713 | |
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.704 | |
| Hoxd13 | homeobox D13 | 0.698 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.686 | |
| Tbx15 | T-box 15 | 0.663 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.662 | |
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.659 | |
| Trp63 | transformation related protein 63 | 0.647 | |
| Sox11 | SRY-box containing gene 11 | 0.637 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.630 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.627 | |
| Bmper | BMP-binding endothelial regulator | 0.627 | |
| Hoxa11 | homeobox A11 | 0.625 | |
| Fzd8 | frizzled homolog 8 (Drosophila) | 0.607 | |
| Hoxa4 | homeobox A4 | 0.602 | |
| Tead3 | TEA domain family member 3 | 0.600 | |
| Pax9 | paired box gene 9 | 0.586 | |
| Pax1 | paired box gene 1 | 0.586 | |
| Hoxa3 | homeobox A3 | 0.565 | |
| Bmp2 | bone morphogenetic protein 2 | 0.564 | |
| Hmx3 | H6 homeobox 3 | 0.552 | |
| Col13a1 | collagen, type XIII, alpha 1 | 0.540 | |
| Pax6 | paired box gene 6 | 0.536 | |
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.530 | |
| Psen1 | presenilin 1 | 0.521 |