Process View
The network for 'regulation of protein autophosphorylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Fyn | Fyn proto-oncogene | 0.990 | |
Ephb2 | Eph receptor B2 | 0.974 | |
Fos | FBJ osteosarcoma oncogene | 0.942 | |
Epha4 | Eph receptor A4 | 0.936 | |
Ptk2 | PTK2 protein tyrosine kinase 2 | 0.884 | |
Efnb1 | ephrin B1 | 0.880 | |
Efnb2 | ephrin B2 | 0.814 | |
Dusp1 | dual specificity phosphatase 1 | 0.572 | |
Ret | ret proto-oncogene | 0.526 | |
Src | Rous sarcoma oncogene | 0.524 | |
Pxn | paxillin | 0.400 | |
Zfp36 | zinc finger protein 36 | 0.398 | |
Ephb3 | Eph receptor B3 | 0.385 | |
Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.341 | |
Prkce | protein kinase C, epsilon | 0.324 | |
Acvrl1 | activin A receptor, type II-like 1 | 0.312 | |
Dll4 | delta-like 4 (Drosophila) | 0.266 | |
Grb2 | growth factor receptor bound protein 2 | 0.253 | |
Tnks1bp1 | tankyrase 1 binding protein 1 | 0.214 | |
Ptpn12 | protein tyrosine phosphatase, non-receptor type 12 | 0.211 | |
Rap1b | RAS related protein 1b | 0.195 | |
Klf6 | Kruppel-like factor 6 | 0.166 | |
Mre11a | meiotic recombination 11 homolog A (S. cerevisiae) | 0.163 | |
Plxna1 | plexin A1 | 0.137 | |
Atf3 | activating transcription factor 3 | 0.118 | |
Itga5 | integrin alpha 5 (fibronectin receptor alpha) | 0.116 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.102 | |
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.101 | |
Mapk8 | mitogen-activated protein kinase 8 | 0.095 | |
Igbp1 | immunoglobulin (CD79A) binding protein 1 | 0.094 | |
Gfra1 | glial cell line derived neurotrophic factor family receptor alpha 1 | 0.092 | |
Cbl | Casitas B-lineage lymphoma | 0.088 | |
Mapk14 | mitogen-activated protein kinase 14 | 0.081 | |
Sept7 | septin 7 | 0.079 | |
Plxna4 | plexin A4 | 0.078 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.074 | |
Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.067 | |
Mcl1 | myeloid cell leukemia sequence 1 | 0.067 | |
Bcar1 | breast cancer anti-estrogen resistance 1 | 0.067 | |
Tgfbr1 | transforming growth factor, beta receptor I | 0.067 | |
Nbn | nibrin | 0.065 | |
Gata5 | GATA binding protein 5 | 0.061 | |
Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.061 | |
Arhgef15 | Rho guanine nucleotide exchange factor (GEF) 15 | 0.061 | |
Lmna | lamin A | 0.061 | |
Jak2 | Janus kinase 2 | 0.060 | |
Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.059 | |
Lck | lymphocyte protein tyrosine kinase | 0.058 | |
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.057 | |
Cdc42ep1 | CDC42 effector protein (Rho GTPase binding) 1 | 0.057 | |
Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.054 | |
Itga3 | integrin alpha 3 | 0.051 | |
Mapk1 | mitogen-activated protein kinase 1 | 0.051 | |
Cdk5r1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.051 | |
Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.050 | |
Btg2 | B-cell translocation gene 2, anti-proliferative | 0.050 | |
Egfr | epidermal growth factor receptor | 0.050 | |
Emp2 | epithelial membrane protein 2 | 0.049 | |
Capza2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.048 | |
Junb | Jun-B oncogene | 0.047 | |
Efs | embryonal Fyn-associated substrate | 0.043 | |
Hbegf | heparin-binding EGF-like growth factor | 0.042 | |
Efna5 | ephrin A5 | 0.040 | |
Tspan9 | tetraspanin 9 | 0.039 | |
Actr3 | ARP3 actin-related protein 3 homolog (yeast) | 0.039 | |
Rassf5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.038 | |
Nrp1 | neuropilin 1 | 0.038 | |
Zfpm2 | zinc finger protein, multitype 2 | 0.036 | |
Rhob | ras homolog gene family, member B | 0.035 | |
Lama5 | laminin, alpha 5 | 0.035 | |
Phox2a | paired-like homeobox 2a | 0.035 | |
Fjx1 | four jointed box 1 (Drosophila) | 0.035 | |
Erbb2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.034 | |
Jup | junction plakoglobin | 0.034 | |
Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.033 | |
Mtpn | myotrophin | 0.032 | |
Dusp6 | dual specificity phosphatase 6 | 0.031 | |
Cx3cl1 | chemokine (C-X3-C motif) ligand 1 | 0.031 | |
Pip4k2a | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.031 | |
Rap1a | RAS-related protein-1a | 0.031 | |
Egr1 | early growth response 1 | 0.031 | |
Zfp703 | zinc finger protein 703 | 0.031 | |
Pag1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.031 | |
Fzd2 | frizzled homolog 2 (Drosophila) | 0.030 | |
Shc1 | src homology 2 domain-containing transforming protein C1 | 0.030 | |
Efna1 | ephrin A1 | 0.030 | |
Wdr26 | WD repeat domain 26 | 0.030 | |
Runx1t1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.029 | |
Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.028 | |
Jun | Jun oncogene | 0.028 | |
Ptk2b | PTK2 protein tyrosine kinase 2 beta | 0.027 | |
Ppp1r15a | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.026 | |
Mapk9 | mitogen-activated protein kinase 9 | 0.026 | |
Vav1 | vav 1 oncogene | 0.026 | |
Bok | BCL2-related ovarian killer protein | 0.025 | |
Csf1 | colony stimulating factor 1 (macrophage) | 0.025 | |
Nck2 | non-catalytic region of tyrosine kinase adaptor protein 2 | 0.025 | |
Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.024 | |
Gdnf | glial cell line derived neurotrophic factor | 0.024 | |
Rasa1 | RAS p21 protein activator 1 | 0.023 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 1.000 | |
RAD50 | RAD50 homolog (S. cerevisiae) | 0.980 | |
NBN | nibrin | 0.957 | |
TOLLIP | toll interacting protein | 0.956 | |
MDC1 | mediator of DNA-damage checkpoint 1 | 0.956 | |
FANCD2 | Fanconi anemia, complementation group D2 | 0.936 | |
VEGFA | vascular endothelial growth factor A | 0.821 | |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.744 | |
IER3 | immediate early response 3 | 0.719 | |
FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.664 | |
H2AFX | H2A histone family, member X | 0.651 | |
ATM | ataxia telangiectasia mutated | 0.268 | |
BRCA1 | breast cancer 1, early onset | 0.198 | |
NRP1 | neuropilin 1 | 0.165 | |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.146 | |
ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.121 | |
ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 0.089 | |
PGF | placental growth factor | 0.077 | |
PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.065 | |
RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.059 | |
TP53BP1 | tumor protein p53 binding protein 1 | 0.049 | |
KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.048 | |
TGFB1 | transforming growth factor, beta 1 | 0.046 | |
RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.045 | |
SFN | stratifin | 0.039 | |
PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.035 | |
COL6A1 | collagen, type VI, alpha 1 | 0.034 | |
PLCG1 | phospholipase C, gamma 1 | 0.034 | |
ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.034 | |
PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.033 | |
RBBP8 | retinoblastoma binding protein 8 | 0.031 | |
SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | 0.029 | |
PTPRB | protein tyrosine phosphatase, receptor type, B | 0.029 | |
PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.027 | |
RUNDC3A | RUN domain containing 3A | 0.027 | |
RNF8 | ring finger protein 8 | 0.026 | |
STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.025 | |
IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.025 | |
GRB10 | growth factor receptor-bound protein 10 | 0.025 | |
KRAS | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.023 | |
COL4A1 | collagen, type IV, alpha 1 | 0.021 | |
TOM1 | target of myb1 (chicken) | 0.020 | |
DDIT3 | DNA-damage-inducible transcript 3 | 0.019 | |
PDGFA | platelet-derived growth factor alpha polypeptide | 0.019 | |
PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.018 | |
PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.018 | |
RAB21 | RAB21, member RAS oncogene family | 0.017 | |
RALGDS | ral guanine nucleotide dissociation stimulator | 0.017 | |
TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 0.017 | |
NOMO1 | NODAL modulator 1 | 0.016 | |
ADAM15 | ADAM metallopeptidase domain 15 | 0.016 | |
EFNA5 | ephrin-A5 | 0.015 | |
TOM1L1 | target of myb1 (chicken)-like 1 | 0.015 | |
PYDC2 | pyrin domain containing 2 | 0.014 | |
RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.014 | |
ACACA | acetyl-CoA carboxylase alpha | 0.014 | |
CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.013 | |
MUC1 | mucin 1, cell surface associated | 0.013 | |
MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.012 | |
CLTC | clathrin, heavy chain (Hc) | 0.012 | |
CYTB | cytochrome b | 0.012 | |
SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.012 | |
RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.012 | |
IRS2 | insulin receptor substrate 2 | 0.012 | |
PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.012 | |
CD22 | CD22 molecule | 0.011 | |
SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.011 | |
PYCARD | PYD and CARD domain containing | 0.011 | |
GLUD2 | glutamate dehydrogenase 2 | 0.011 | |
STAB1 | stabilin 1 | 0.011 | |
SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.010 |