The network for 'regulation of protein autophosphorylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of protein autophosphorylation

Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues.

Name Description Probability Func Analog Organism
Fyn Fyn proto-oncogene 0.990
Ephb2 Eph receptor B2 0.974
Fos FBJ osteosarcoma oncogene 0.942
Epha4 Eph receptor A4 0.936
Ptk2 PTK2 protein tyrosine kinase 2 0.884
Efnb1 ephrin B1 0.880
Efnb2 ephrin B2 0.814
Dusp1 dual specificity phosphatase 1 0.572
Ret ret proto-oncogene 0.526
Src Rous sarcoma oncogene 0.524
Pxn paxillin 0.400
Zfp36 zinc finger protein 36 0.398
Ephb3 Eph receptor B3 0.385
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.341
Prkce protein kinase C, epsilon 0.324
Acvrl1 activin A receptor, type II-like 1 0.312
Dll4 delta-like 4 (Drosophila) 0.266
Grb2 growth factor receptor bound protein 2 0.253
Tnks1bp1 tankyrase 1 binding protein 1 0.214
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.211
Rap1b RAS related protein 1b 0.195
Klf6 Kruppel-like factor 6 0.166
Mre11a meiotic recombination 11 homolog A (S. cerevisiae) 0.163
Plxna1 plexin A1 0.137
Atf3 activating transcription factor 3 0.118
Itga5 integrin alpha 5 (fibronectin receptor alpha) 0.116
Tgfbr2 transforming growth factor, beta receptor II 0.102
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.101
Mapk8 mitogen-activated protein kinase 8 0.095
Igbp1 immunoglobulin (CD79A) binding protein 1 0.094
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.092
Cbl Casitas B-lineage lymphoma 0.088
Mapk14 mitogen-activated protein kinase 14 0.081
Sept7 septin 7 0.079
Plxna4 plexin A4 0.078
Nos3 nitric oxide synthase 3, endothelial cell 0.074
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.067
Mcl1 myeloid cell leukemia sequence 1 0.067
Bcar1 breast cancer anti-estrogen resistance 1 0.067
Tgfbr1 transforming growth factor, beta receptor I 0.067
Nbn nibrin 0.065
Gata5 GATA binding protein 5 0.061
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.061
Arhgef15 Rho guanine nucleotide exchange factor (GEF) 15 0.061
Lmna lamin A 0.061
Jak2 Janus kinase 2 0.060
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.059
Lck lymphocyte protein tyrosine kinase 0.058
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.057
Cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.057
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.054
Itga3 integrin alpha 3 0.051
Mapk1 mitogen-activated protein kinase 1 0.051
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.051
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.050
Btg2 B-cell translocation gene 2, anti-proliferative 0.050
Egfr epidermal growth factor receptor 0.050
Emp2 epithelial membrane protein 2 0.049
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.048
Junb Jun-B oncogene 0.047
Efs embryonal Fyn-associated substrate 0.043
Hbegf heparin-binding EGF-like growth factor 0.042
Efna5 ephrin A5 0.040
Tspan9 tetraspanin 9 0.039
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.039
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.038
Nrp1 neuropilin 1 0.038
Zfpm2 zinc finger protein, multitype 2 0.036
Rhob ras homolog gene family, member B 0.035
Lama5 laminin, alpha 5 0.035
Phox2a paired-like homeobox 2a 0.035
Fjx1 four jointed box 1 (Drosophila) 0.035
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.034
Jup junction plakoglobin 0.034
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.033
Mtpn myotrophin 0.032
Dusp6 dual specificity phosphatase 6 0.031
Cx3cl1 chemokine (C-X3-C motif) ligand 1 0.031
Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.031
Rap1a RAS-related protein-1a 0.031
Egr1 early growth response 1 0.031
Zfp703 zinc finger protein 703 0.031
Pag1 phosphoprotein associated with glycosphingolipid microdomains 1 0.031
Fzd2 frizzled homolog 2 (Drosophila) 0.030
Shc1 src homology 2 domain-containing transforming protein C1 0.030
Efna1 ephrin A1 0.030
Wdr26 WD repeat domain 26 0.030
Runx1t1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.029
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.028
Jun Jun oncogene 0.028
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.027
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.026
Mapk9 mitogen-activated protein kinase 9 0.026
Vav1 vav 1 oncogene 0.026
Bok BCL2-related ovarian killer protein 0.025
Csf1 colony stimulating factor 1 (macrophage) 0.025
Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 0.025
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.024
Gdnf glial cell line derived neurotrophic factor 0.024
Rasa1 RAS p21 protein activator 1 0.023
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 1.000
RAD50 RAD50 homolog (S. cerevisiae) 0.980
NBN nibrin 0.957
TOLLIP toll interacting protein 0.956
MDC1 mediator of DNA-damage checkpoint 1 0.956
FANCD2 Fanconi anemia, complementation group D2 0.936
VEGFA vascular endothelial growth factor A 0.821
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.744
IER3 immediate early response 3 0.719
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.664
H2AFX H2A histone family, member X 0.651
ATM ataxia telangiectasia mutated 0.268
BRCA1 breast cancer 1, early onset 0.198
NRP1 neuropilin 1 0.165
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.146
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.121
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.089
PGF placental growth factor 0.077
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.065
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.059
TP53BP1 tumor protein p53 binding protein 1 0.049
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.048
TGFB1 transforming growth factor, beta 1 0.046
RIPK2 receptor-interacting serine-threonine kinase 2 0.045
SFN stratifin 0.039
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.035
COL6A1 collagen, type VI, alpha 1 0.034
PLCG1 phospholipase C, gamma 1 0.034
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.034
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.033
RBBP8 retinoblastoma binding protein 8 0.031
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 0.029
PTPRB protein tyrosine phosphatase, receptor type, B 0.029
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.027
RUNDC3A RUN domain containing 3A 0.027
RNF8 ring finger protein 8 0.026
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.025
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.025
GRB10 growth factor receptor-bound protein 10 0.025
KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.023
COL4A1 collagen, type IV, alpha 1 0.021
TOM1 target of myb1 (chicken) 0.020
DDIT3 DNA-damage-inducible transcript 3 0.019
PDGFA platelet-derived growth factor alpha polypeptide 0.019
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.018
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 0.018
RAB21 RAB21, member RAS oncogene family 0.017
RALGDS ral guanine nucleotide dissociation stimulator 0.017
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.017
NOMO1 NODAL modulator 1 0.016
ADAM15 ADAM metallopeptidase domain 15 0.016
EFNA5 ephrin-A5 0.015
TOM1L1 target of myb1 (chicken)-like 1 0.015
PYDC2 pyrin domain containing 2 0.014
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.014
ACACA acetyl-CoA carboxylase alpha 0.014
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.013
MUC1 mucin 1, cell surface associated 0.013
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.012
CLTC clathrin, heavy chain (Hc) 0.012
CYTB cytochrome b 0.012
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.012
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.012
IRS2 insulin receptor substrate 2 0.012
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.012
CD22 CD22 molecule 0.011
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.011
PYCARD PYD and CARD domain containing 0.011
GLUD2 glutamate dehydrogenase 2 0.011
STAB1 stabilin 1 0.011
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism