IMP
Process View
The network for 'embryonic digit morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
embryonic digit morphogenesis
The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Gli3 | GLI-Kruppel family member GLI3 | 1.000 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.999 | |
| Shh | sonic hedgehog | 0.999 | |
| Msx1 | homeobox, msh-like 1 | 0.993 | |
| Nodal | nodal | 0.991 | |
| Tbx3 | T-box 3 | 0.991 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.990 | |
| Hoxd11 | homeobox D11 | 0.988 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.986 | |
| Pax6 | paired box gene 6 | 0.986 | |
| Fgf8 | fibroblast growth factor 8 | 0.984 | |
| Hoxa11 | homeobox A11 | 0.976 | |
| Pax2 | paired box gene 2 | 0.974 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.974 | |
| Foxc1 | forkhead box C1 | 0.974 | |
| Sall4 | sal-like 4 (Drosophila) | 0.973 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.959 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.954 | |
| Bmp7 | bone morphogenetic protein 7 | 0.952 | |
| Sox2 | SRY-box containing gene 2 | 0.949 | |
| Lhx1 | LIM homeobox protein 1 | 0.940 | |
| Pax3 | paired box gene 3 | 0.938 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.936 | |
| Bmp4 | bone morphogenetic protein 4 | 0.933 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.923 | |
| Runx2 | runt related transcription factor 2 | 0.919 | |
| Msx2 | homeobox, msh-like 2 | 0.918 | |
| Mks1 | Meckel syndrome, type 1 | 0.917 | |
| Prrx2 | paired related homeobox 2 | 0.902 | |
| Prrx1 | paired related homeobox 1 | 0.883 | |
| Hoxd13 | homeobox D13 | 0.871 | |
| Sox9 | SRY-box containing gene 9 | 0.868 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.868 | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.854 | |
| Tbx5 | T-box 5 | 0.848 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.845 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.842 | |
| Dlx5 | distal-less homeobox 5 | 0.838 | |
| Fgf10 | fibroblast growth factor 10 | 0.826 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.825 | |
| Gpc3 | glypican 3 | 0.820 | |
| Sfrp2 | secreted frizzled-related protein 2 | 0.818 | |
| Wnt5a | wingless-related MMTV integration site 5A | 0.813 | |
| Pax8 | paired box gene 8 | 0.799 | |
| Chrd | chordin | 0.777 | |
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.773 | |
| Fzd1 | frizzled homolog 1 (Drosophila) | 0.768 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.760 | |
| Foxc2 | forkhead box C2 | 0.755 | |
| Alx4 | aristaless-like homeobox 4 | 0.744 | |
| Wt1 | Wilms tumor 1 homolog | 0.737 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.736 | |
| Hoxa1 | homeobox A1 | 0.735 | |
| Smad4 | MAD homolog 4 (Drosophila) | 0.725 | |
| Pten | phosphatase and tensin homolog | 0.714 | |
| Smo | smoothened homolog (Drosophila) | 0.711 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.709 | |
| Tbx15 | T-box 15 | 0.691 | |
| Acvr1 | activin A receptor, type 1 | 0.676 | |
| Foxd3 | forkhead box D3 | 0.662 | |
| Sall1 | sal-like 1 (Drosophila) | 0.662 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.654 | |
| Tbx1 | T-box 1 | 0.646 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.638 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.618 | |
| Wnt6 | wingless-related MMTV integration site 6 | 0.618 | |
| Rarg | retinoic acid receptor, gamma | 0.601 | |
| Hcn4 | hyperpolarization-activated, cyclic nucleotide-gated K+ 4 | 0.596 | |
| Hoxa10 | homeobox A10 | 0.584 | |
| Hoxd9 | homeobox D9 | 0.577 | |
| Foxh1 | forkhead box H1 | 0.566 | |
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.557 | |
| Foxd2 | forkhead box D2 | 0.552 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.548 | |
| Gsc | goosecoid homeobox | 0.548 | |
| En1 | engrailed 1 | 0.544 | |
| Rara | retinoic acid receptor, alpha | 0.537 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.534 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.511 | |
| Neurog3 | neurogenin 3 | 0.504 | |
| Jag1 | jagged 1 | 0.501 | |
| Ptk7 | PTK7 protein tyrosine kinase 7 | 0.490 | |
| Bax | BCL2-associated X protein | 0.488 | |
| Nkx2-1 | NK2 homeobox 1 | 0.486 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.486 | |
| Dab1 | disabled homolog 1 (Drosophila) | 0.477 | |
| Pax9 | paired box gene 9 | 0.473 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.471 | |
| Uncx | UNC homeobox | 0.470 | |
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.460 | |
| Fzd2 | frizzled homolog 2 (Drosophila) | 0.452 | |
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.450 | |
| Esrrb | estrogen related receptor, beta | 0.443 | |
| Hoxa13 | homeobox A13 | 0.439 | |
| Gdf11 | growth differentiation factor 11 | 0.435 | |
| Bmpr1b | bone morphogenetic protein receptor, type 1B | 0.433 | |
| Hoxd10 | homeobox D10 | 0.433 | |
| Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.431 | |
| Efnb1 | ephrin B1 | 0.430 | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.425 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| HDAC2 | histone deacetylase 2 | 0.971 | |
| BMP2 | bone morphogenetic protein 2 | 0.962 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.912 | |
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.702 | |
| BCL2L1 | BCL2-like 1 | 0.445 | |
| TJP1 | tight junction protein 1 (zona occludens 1) | 0.417 | |
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.266 | |
| JAG1 | jagged 1 | 0.249 | |
| GATA4 | GATA binding protein 4 | 0.208 | |
| FGF18 | fibroblast growth factor 18 | 0.206 | |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.196 | |
| NOTCH3 | notch 3 | 0.170 | |
| BAK1 | BCL2-antagonist/killer 1 | 0.163 | |
| BAX | BCL2-associated X protein | 0.111 | |
| MSX1 | msh homeobox 1 | 0.086 | |
| ARRB1 | arrestin, beta 1 | 0.084 | |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.078 | |
| BMP7 | bone morphogenetic protein 7 | 0.073 | |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.073 | |
| HOXD13 | homeobox D13 | 0.060 | |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.058 | |
| MSX2 | msh homeobox 2 | 0.057 | |
| COL2A1 | collagen, type II, alpha 1 | 0.055 | |
| HOXA10 | homeobox A10 | 0.051 | |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.047 | |
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.046 | |
| BMP4 | bone morphogenetic protein 4 | 0.046 | |
| DKK1 | dickkopf homolog 1 (Xenopus laevis) | 0.043 | |
| HOXD9 | homeobox D9 | 0.040 | |
| FSTL1 | follistatin-like 1 | 0.036 | |
| HDAC1 | histone deacetylase 1 | 0.034 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.033 | |
| CAPRIN2 | caprin family member 2 | 0.032 | |
| TBX5 | T-box 5 | 0.031 | |
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.028 | |
| SFRP1 | secreted frizzled-related protein 1 | 0.027 | |
| FZD1 | frizzled homolog 1 (Drosophila) | 0.027 | |
| DLX4 | distal-less homeobox 4 | 0.025 | |
| WNT3A | wingless-type MMTV integration site family, member 3A | 0.024 | |
| RNF144B | ring finger protein 144B | 0.023 | |
| FOXF2 | forkhead box F2 | 0.023 | |
| NGFR | nerve growth factor receptor | 0.023 | |
| MAX | MYC associated factor X | 0.023 | |
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.022 | |
| BAD | BCL2-associated agonist of cell death | 0.022 | |
| HOXA11 | homeobox A11 | 0.022 | |
| FEV | FEV (ETS oncogene family) | 0.022 | |
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.022 | |
| FGF3 | fibroblast growth factor 3 | 0.020 | |
| HOXD10 | homeobox D10 | 0.019 | |
| MAML1 | mastermind-like 1 (Drosophila) | 0.019 | |
| DLX5 | distal-less homeobox 5 | 0.017 | |
| LBX1 | ladybird homeobox 1 | 0.016 | |
| BID | BH3 interacting domain death agonist | 0.016 | |
| TBX2 | T-box 2 | 0.015 | |
| TUBB8 | tubulin, beta 8 | 0.015 | |
| WIF1 | WNT inhibitory factor 1 | 0.015 | |
| NKX3-2 | NK3 homeobox 2 | 0.014 | |
| STK36 | serine/threonine kinase 36 | 0.014 | |
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.014 | |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.013 | |
| WNT11 | wingless-type MMTV integration site family, member 11 | 0.013 | |
| TBX1 | T-box 1 | 0.013 | |
| HOXA5 | homeobox A5 | 0.013 | |
| POU4F3 | POU class 4 homeobox 3 | 0.013 | |
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.013 | |
| HOXC8 | homeobox C8 | 0.013 | |
| HOXC6 | homeobox C6 | 0.012 | |
| HES2 | hairy and enhancer of split 2 (Drosophila) | 0.012 | |
| HOXD11 | homeobox D11 | 0.012 | |
| PAX3 | paired box 3 | 0.012 | |
| HOXB13 | homeobox B13 | 0.012 | |
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.011 | |
| CDK6 | cyclin-dependent kinase 6 | 0.011 | |
| FOXL1 | forkhead box L1 | 0.010 | |
| DPY19L4 | dpy-19-like 4 (C. elegans) | 0.010 | |
| PRDM8 | PR domain containing 8 | 0.010 | |
| SIX2 | SIX homeobox 2 | 0.010 | |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.010 | |
| WNT1 | wingless-type MMTV integration site family, member 1 | 0.010 |