The network for 'blastocyst formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

blastocyst formation

The initial formation of a blastocyst from a solid ball of cells known as a morula.

Name Description Probability Func Analog Organism
Pitx2 paired-like homeodomain transcription factor 2 0.999
Tcfap2a transcription factor AP-2, alpha 0.997
Shh sonic hedgehog 0.996
Gli3 GLI-Kruppel family member GLI3 0.995
Fgfr2 fibroblast growth factor receptor 2 0.994
Otx2 orthodenticle homolog 2 (Drosophila) 0.992
Tbx3 T-box 3 0.990
Fgf8 fibroblast growth factor 8 0.985
Hand1 heart and neural crest derivatives expressed transcript 1 0.985
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.984
Pax3 paired box gene 3 0.981
Hand2 heart and neural crest derivatives expressed transcript 2 0.976
Bmp4 bone morphogenetic protein 4 0.956
Foxc1 forkhead box C1 0.954
Sox2 SRY-box containing gene 2 0.952
Pax2 paired box gene 2 0.925
Msx2 homeobox, msh-like 2 0.899
Jag1 jagged 1 0.884
Hoxd13 homeobox D13 0.883
Alx4 aristaless-like homeobox 4 0.864
Nanog Nanog homeobox 0.850
Pou5f1 POU domain, class 5, transcription factor 1 0.834
Hoxa13 homeobox A13 0.821
Chd7 chromodomain helicase DNA binding protein 7 0.813
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.788
Eya1 eyes absent 1 homolog (Drosophila) 0.776
Foxc2 forkhead box C2 0.775
Fgf3 fibroblast growth factor 3 0.761
Ctnnb1 catenin (cadherin associated protein), beta 1 0.760
Zic3 zinc finger protein of the cerebellum 3 0.737
Gata4 GATA binding protein 4 0.727
Tlx3 T-cell leukemia, homeobox 3 0.727
Cdx2 caudal type homeobox 2 0.719
Hoxa1 homeobox A1 0.702
Sall4 sal-like 4 (Drosophila) 0.671
Lhx1 LIM homeobox protein 1 0.652
Dlx5 distal-less homeobox 5 0.640
Fgfr1 fibroblast growth factor receptor 1 0.617
Foxh1 forkhead box H1 0.611
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.598
Pitx1 paired-like homeodomain transcription factor 1 0.598
Tcfap2c transcription factor AP-2, gamma 0.592
Kiss1 KiSS-1 metastasis-suppressor 0.576
Nr0b1 nuclear receptor subfamily 0, group B, member 1 0.558
Pten phosphatase and tensin homolog 0.555
T brachyury 0.552
Pax6 paired box gene 6 0.543
Foxg1 forkhead box G1 0.536
Msx1 homeobox, msh-like 1 0.515
Gbx2 gastrulation brain homeobox 2 0.501
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.491
Fos FBJ osteosarcoma oncogene 0.478
Isl1 ISL1 transcription factor, LIM/homeodomain 0.478
Nog noggin 0.476
Hes1 hairy and enhancer of split 1 (Drosophila) 0.460
Fgfr3 fibroblast growth factor receptor 3 0.451
Arid1a AT rich interactive domain 1A (SWI-like) 0.448
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.431
Tbx1 T-box 1 0.430
Smad6 MAD homolog 6 (Drosophila) 0.416
En1 engrailed 1 0.415
Prrx1 paired related homeobox 1 0.393
En2 engrailed 2 0.391
Foxd3 forkhead box D3 0.385
Nodal nodal 0.383
Bmp7 bone morphogenetic protein 7 0.380
Sall3 sal-like 3 (Drosophila) 0.353
Lmx1b LIM homeobox transcription factor 1 beta 0.337
Wnt6 wingless-related MMTV integration site 6 0.336
Lef1 lymphoid enhancer binding factor 1 0.332
Hmx3 H6 homeobox 3 0.303
Nf1 neurofibromatosis 1 0.303
Sin3a transcriptional regulator, SIN3A (yeast) 0.302
Insm1 insulinoma-associated 1 0.298
Zeb1 zinc finger E-box binding homeobox 1 0.295
Mecom MDS1 and EVI1 complex locus 0.283
Pax8 paired box gene 8 0.283
Sox3 SRY-box containing gene 3 0.278
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.275
Hoxd11 homeobox D11 0.273
Hoxd9 homeobox D9 0.270
Nos3 nitric oxide synthase 3, endothelial cell 0.268
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.262
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.261
Fgf17 fibroblast growth factor 17 0.261
Vangl2 vang-like 2 (van gogh, Drosophila) 0.260
Hoxb13 homeobox B13 0.259
Phlda2 pleckstrin homology-like domain, family A, member 2 0.259
Efnb2 ephrin B2 0.256
Tbx15 T-box 15 0.252
Cldn1 claudin 1 0.251
Fgf4 fibroblast growth factor 4 0.243
Fgf15 fibroblast growth factor 15 0.242
Gata6 GATA binding protein 6 0.240
Gata3 GATA binding protein 3 0.233
Sall1 sal-like 1 (Drosophila) 0.231
Foxa1 forkhead box A1 0.230
Rb1 retinoblastoma 1 0.227
Zic2 zinc finger protein of the cerebellum 2 0.225
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.223
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
POU5F1 POU class 5 homeobox 1 0.964
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.962
GABPA GA binding protein transcription factor, alpha subunit 60kDa 0.924
FOXD3 forkhead box D3 0.924
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.807
AATF apoptosis antagonizing transcription factor 0.530
EP300 E1A binding protein p300 0.518
SP1 Sp1 transcription factor 0.495
SMAD4 SMAD family member 4 0.488
CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.452
SETD8 SET domain containing (lysine methyltransferase) 8 0.451
CREBBP CREB binding protein 0.429
MYOD1 myogenic differentiation 1 0.428
IER2 immediate early response 2 0.420
SMAD7 SMAD family member 7 0.417
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.412
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.405
SOX2 SRY (sex determining region Y)-box 2 0.391
JUN jun proto-oncogene 0.377
MKL1 megakaryoblastic leukemia (translocation) 1 0.356
CTNND1 catenin (cadherin-associated protein), delta 1 0.329
CNOT2 CCR4-NOT transcription complex, subunit 2 0.329
OCLN occludin 0.299
HNF4A hepatocyte nuclear factor 4, alpha 0.298
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.296
GATA2 GATA binding protein 2 0.292
SKI v-ski sarcoma viral oncogene homolog (avian) 0.243
C10orf2 chromosome 10 open reading frame 2 0.224
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 0.222
TCF12 transcription factor 12 0.218
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.205
ATF7IP activating transcription factor 7 interacting protein 0.190
FOS FBJ murine osteosarcoma viral oncogene homolog 0.185
PDX1 pancreatic and duodenal homeobox 1 0.173
GJA1 gap junction protein, alpha 1, 43kDa 0.166
MYOCD myocardin 0.165
SMAD3 SMAD family member 3 0.163
RUNX1 runt-related transcription factor 1 0.161
MYOG myogenin (myogenic factor 4) 0.160
TRIM33 tripartite motif containing 33 0.159
HNF1A HNF1 homeobox A 0.146
SP3 Sp3 transcription factor 0.144
POLR1E polymerase (RNA) I polypeptide E, 53kDa 0.122
POU2F1 POU class 2 homeobox 1 0.120
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.116
MED15 mediator complex subunit 15 0.111
PTPRJ protein tyrosine phosphatase, receptor type, J 0.102
GATA4 GATA binding protein 4 0.097
PPAN peter pan homolog (Drosophila) 0.093
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.092
JUND jun D proto-oncogene 0.091
KRT8 keratin 8 0.085
NFYA nuclear transcription factor Y, alpha 0.081
PRRC2A proline-rich coiled-coil 2A 0.076
IPO4 importin 4 0.074
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.072
MTA1 metastasis associated 1 0.071
UBIAD1 UbiA prenyltransferase domain containing 1 0.069
PSEN1 presenilin 1 0.066
PUM2 pumilio homolog 2 (Drosophila) 0.062
SPOP speckle-type POZ protein 0.062
LMO2 LIM domain only 2 (rhombotin-like 1) 0.062
PPARA peroxisome proliferator-activated receptor alpha 0.061
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.060
TJP2 tight junction protein 2 (zona occludens 2) 0.059
HOXD12 homeobox D12 0.057
TCF4 transcription factor 4 0.057
SREBF2 sterol regulatory element binding transcription factor 2 0.056
YY1 YY1 transcription factor 0.056
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.056
HIPK2 homeodomain interacting protein kinase 2 0.055
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.055
VMP1 vacuole membrane protein 1 0.054
KBTBD7 kelch repeat and BTB (POZ) domain containing 7 0.053
ZFYVE9 zinc finger, FYVE domain containing 9 0.053
ETS2 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) 0.052
NCOR2 nuclear receptor corepressor 2 0.052
TROAP trophinin associated protein (tastin) 0.051
ESR2 estrogen receptor 2 (ER beta) 0.051
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.047
PDLIM1 PDZ and LIM domain 1 0.047
CCDC86 coiled-coil domain containing 86 0.046
ELF1 E74-like factor 1 (ets domain transcription factor) 0.046
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.046
MKL2 MKL/myocardin-like 2 0.045
SFRP5 secreted frizzled-related protein 5 0.045
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.045
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 0.044
FOSL1 FOS-like antigen 1 0.044
TAL1 T-cell acute lymphocytic leukemia 1 0.043
METTL1 methyltransferase like 1 0.043
ACTN4 actinin, alpha 4 0.043
JUP junction plakoglobin 0.042
WDR61 WD repeat domain 61 0.041
STRN4 striatin, calmodulin binding protein 4 0.041
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.041
GJD3 gap junction protein, delta 3, 31.9kDa 0.040
CNOT8 CCR4-NOT transcription complex, subunit 8 0.040
EPAS1 endothelial PAS domain protein 1 0.040
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.039
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism