IMP
Process View
The network for 'hemangioblast cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
hemangioblast cell differentiation
The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Shh | sonic hedgehog | 1.000 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 1.000 | |
| Pax6 | paired box gene 6 | 1.000 | |
| Neurod1 | neurogenic differentiation 1 | 1.000 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 1.000 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.999 | |
| Pax3 | paired box gene 3 | 0.995 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.995 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.995 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.991 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.988 | |
| Fgf8 | fibroblast growth factor 8 | 0.984 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.977 | |
| Foxc2 | forkhead box C2 | 0.973 | |
| Msx1 | homeobox, msh-like 1 | 0.970 | |
| Gsc | goosecoid homeobox | 0.958 | |
| Onecut1 | one cut domain, family member 1 | 0.947 | |
| Foxc1 | forkhead box C1 | 0.918 | |
| Hoxd13 | homeobox D13 | 0.918 | |
| En1 | engrailed 1 | 0.914 | |
| Prrx2 | paired related homeobox 2 | 0.897 | |
| Sox9 | SRY-box containing gene 9 | 0.878 | |
| Gata4 | GATA binding protein 4 | 0.878 | |
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.875 | |
| Ptf1a | pancreas specific transcription factor, 1a | 0.859 | |
| Msx2 | homeobox, msh-like 2 | 0.853 | |
| Nkx3-2 | NK3 homeobox 2 | 0.828 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.825 | |
| Lhx3 | LIM homeobox protein 3 | 0.808 | |
| Gata1 | GATA binding protein 1 | 0.806 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.788 | |
| Neurog2 | neurogenin 2 | 0.783 | |
| Hoxa1 | homeobox A1 | 0.780 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.776 | |
| Prrx1 | paired related homeobox 1 | 0.761 | |
| Alx3 | aristaless-like homeobox 3 | 0.750 | |
| Insm1 | insulinoma-associated 1 | 0.744 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.728 | |
| Gpr50 | G-protein-coupled receptor 50 | 0.728 | |
| Sox11 | SRY-box containing gene 11 | 0.717 | |
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.714 | |
| Nhlh1 | nescient helix loop helix 1 | 0.709 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.701 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.696 | |
| Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.678 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.657 | |
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.637 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.620 | |
| Hoxd11 | homeobox D11 | 0.616 | |
| Six3 | sine oculis-related homeobox 3 homolog (Drosophila) | 0.608 | |
| Runx2 | runt related transcription factor 2 | 0.589 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.588 | |
| Neurog3 | neurogenin 3 | 0.580 | |
| Bmp4 | bone morphogenetic protein 4 | 0.568 | |
| Dlx2 | distal-less homeobox 2 | 0.565 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.559 | |
| Lhx5 | LIM homeobox protein 5 | 0.558 | |
| Lhx9 | LIM homeobox protein 9 | 0.546 | |
| Sox2 | SRY-box containing gene 2 | 0.493 | |
| Neurod4 | neurogenic differentiation 4 | 0.482 | |
| Hoxd1 | homeobox D1 | 0.472 | |
| Foxd2 | forkhead box D2 | 0.469 | |
| Foxg1 | forkhead box G1 | 0.462 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.455 | |
| Tlx3 | T-cell leukemia, homeobox 3 | 0.447 | |
| Hba-x | hemoglobin X, alpha-like embryonic chain in Hba complex | 0.447 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.445 | |
| Smo | smoothened homolog (Drosophila) | 0.431 | |
| Hoxb1 | homeobox B1 | 0.426 | |
| Fgf15 | fibroblast growth factor 15 | 0.425 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.416 | |
| Tbx1 | T-box 1 | 0.408 | |
| Ntf3 | neurotrophin 3 | 0.407 | |
| Dlx5 | distal-less homeobox 5 | 0.402 | |
| Ebf3 | early B-cell factor 3 | 0.382 | |
| Tal2 | T-cell acute lymphocytic leukemia 2 | 0.382 | |
| Hoxa13 | homeobox A13 | 0.362 | |
| Mn1 | meningioma 1 | 0.355 | |
| Mecom | MDS1 and EVI1 complex locus | 0.349 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.348 | |
| Phox2b | paired-like homeobox 2b | 0.345 | |
| Uncx | UNC homeobox | 0.343 | |
| Prph2 | peripherin 2 | 0.342 | |
| Hoxd3 | homeobox D3 | 0.342 | |
| Alx4 | aristaless-like homeobox 4 | 0.323 | |
| Mab21l2 | mab-21-like 2 (C. elegans) | 0.315 | |
| Kiss1 | KiSS-1 metastasis-suppressor | 0.313 | |
| Zic1 | zinc finger protein of the cerebellum 1 | 0.311 | |
| Cyp19a1 | cytochrome P450, family 19, subfamily a, polypeptide 1 | 0.304 | |
| Dlx6 | distal-less homeobox 6 | 0.299 | |
| Pou4f3 | POU domain, class 4, transcription factor 3 | 0.291 | |
| Hoxc5 | homeobox C5 | 0.285 | |
| Pax9 | paired box gene 9 | 0.278 | |
| Neurog1 | neurogenin 1 | 0.277 | |
| Hmx1 | H6 homeobox 1 | 0.270 | |
| Hoxa10 | homeobox A10 | 0.262 | |
| Sim2 | single-minded homolog 2 (Drosophila) | 0.260 | |
| Slc4a1 | solute carrier family 4 (anion exchanger), member 1 | 0.260 | |
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.257 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.255 |
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Danio rerio
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| isl1 | islet1 | 0.204 | |
| atoh1a | atonal homolog 1a | 0.166 | |
| evx1 | even-skipped homeobox 1 | 0.115 | |
| fli1a | friend leukemia integration 1a | 0.092 | |
| gata1a | GATA binding protein 1a | 0.077 | |
| hhex | hematopoietically expressed homeobox | 0.069 | |
| pax2a | paired box gene 2a | 0.067 | |
| ptf1a | pancreas specific transcription factor, 1a | 0.051 | |
| cdh5 | cadherin 5 | 0.040 | |
| atoh1b | atonal homolog 1b | 0.036 | |
| znfl2a | zinc finger-like gene 2a | 0.033 | |
| slc17a7 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 | 0.032 | |
| efnb2a | ephrin B2a | 0.029 | |
| osr2 | odd-skipped related 2 (Drosophila) | 0.020 | |
| etv2 | ets variant gene 2 | 0.020 | |
| fgf8a | fibroblast growth factor 8 a | 0.019 | |
| pea3 | ETS-domain transcription factor pea3 | 0.019 | |
| fgf10a | fibroblast growth factor 10a | 0.018 | |
| jag2 | jagged 2 | 0.018 | |
| kdrl | kinase insert domain receptor like | 0.017 | |
| hoxa9a | homeo box A9a | 0.017 | |
| ascl1a | achaete-scute complex-like 1a (Drosophila) | 0.017 | |
| runx1 | runt-related transcription factor 1 | 0.016 | |
| tbx5a | T-box 5a | 0.014 | |
| hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.014 | |
| foxa1 | forkhead box A1 | 0.014 | |
| mafba | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) | 0.014 | |
| fzd9b | frizzled homolog 9b | 0.013 | |
| lmo2 | LIM domain only 2 (rhombotin-like 1) | 0.013 | |
| eng2b | engrailed 2b | 0.013 | |
| alcama | activated leukocyte cell adhesion molecule a | 0.012 | |
| aldh1a2 | aldehyde dehydrogenase 1 family, member A2 | 0.011 | |
| atoh1c | atonal homolog 1c | 0.011 | |
| hbbe1.1 | hemoglobin beta embryonic-1.1 | 0.011 | |
| bmper | BMP binding endothelial regulator | 0.010 | |
| eng2a | engrailed 2a | 0.010 |