IMP
Process View
The network for 'mitral valve morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
mitral valve morphogenesis
The process in which the structure of the mitral valve is generated and organized.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Gata4 | GATA binding protein 4 | 1.000 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 1.000 | |
| Efnb2 | ephrin B2 | 1.000 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 1.000 | |
| Tgfb2 | transforming growth factor, beta 2 | 1.000 | |
| Pax3 | paired box gene 3 | 1.000 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 1.000 | |
| Jag1 | jagged 1 | 0.999 | |
| Fgf8 | fibroblast growth factor 8 | 0.999 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.999 | |
| Shh | sonic hedgehog | 0.999 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.999 | |
| Ntf3 | neurotrophin 3 | 0.998 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.998 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.997 | |
| Foxc2 | forkhead box C2 | 0.993 | |
| Neurod1 | neurogenic differentiation 1 | 0.993 | |
| Foxc1 | forkhead box C1 | 0.993 | |
| Ephb2 | Eph receptor B2 | 0.989 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.987 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.981 | |
| Pax6 | paired box gene 6 | 0.981 | |
| Sox11 | SRY-box containing gene 11 | 0.979 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.976 | |
| Hoxa1 | homeobox A1 | 0.973 | |
| Bmp4 | bone morphogenetic protein 4 | 0.952 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.937 | |
| Sox9 | SRY-box containing gene 9 | 0.932 | |
| Gata1 | GATA binding protein 1 | 0.925 | |
| Msx1 | homeobox, msh-like 1 | 0.921 | |
| Meox2 | mesenchyme homeobox 2 | 0.910 | |
| Gata6 | GATA binding protein 6 | 0.902 | |
| Vegfa | vascular endothelial growth factor A | 0.900 | |
| Onecut1 | one cut domain, family member 1 | 0.883 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.880 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.871 | |
| Efna2 | ephrin A2 | 0.870 | |
| Smo | smoothened homolog (Drosophila) | 0.868 | |
| Tbx1 | T-box 1 | 0.866 | |
| Gpr50 | G-protein-coupled receptor 50 | 0.865 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.851 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.850 | |
| Hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.840 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.832 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.821 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.801 | |
| Sox2 | SRY-box containing gene 2 | 0.786 | |
| Adam19 | a disintegrin and metallopeptidase domain 19 (meltrin beta) | 0.768 | |
| Neurog3 | neurogenin 3 | 0.751 | |
| Insm1 | insulinoma-associated 1 | 0.741 | |
| Ptf1a | pancreas specific transcription factor, 1a | 0.740 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.729 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.727 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.721 | |
| Foxg1 | forkhead box G1 | 0.702 | |
| Epha4 | Eph receptor A4 | 0.684 | |
| Hoxd13 | homeobox D13 | 0.667 | |
| Nf1 | neurofibromatosis 1 | 0.662 | |
| Sox7 | SRY-box containing gene 7 | 0.661 | |
| En1 | engrailed 1 | 0.649 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.644 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.642 | |
| Prrx1 | paired related homeobox 1 | 0.607 | |
| Gsc | goosecoid homeobox | 0.605 | |
| Fgf10 | fibroblast growth factor 10 | 0.600 | |
| Tcf15 | transcription factor 15 | 0.597 | |
| She | src homology 2 domain-containing transforming protein E | 0.594 | |
| Mecom | MDS1 and EVI1 complex locus | 0.590 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.584 | |
| Neurog2 | neurogenin 2 | 0.548 | |
| Lhx3 | LIM homeobox protein 3 | 0.547 | |
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.533 | |
| Msx2 | homeobox, msh-like 2 | 0.530 | |
| Cxcr4 | chemokine (C-X-C motif) receptor 4 | 0.525 | |
| Mesp1 | mesoderm posterior 1 | 0.522 | |
| Ednra | endothelin receptor type A | 0.518 | |
| Sox4 | SRY-box containing gene 4 | 0.517 | |
| Runx2 | runt related transcription factor 2 | 0.517 | |
| Foxd2 | forkhead box D2 | 0.507 | |
| Tal2 | T-cell acute lymphocytic leukemia 2 | 0.507 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.503 | |
| Rxra | retinoid X receptor alpha | 0.497 | |
| Klf3 | Kruppel-like factor 3 (basic) | 0.477 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.474 | |
| Tbx3 | T-box 3 | 0.469 | |
| Ebf3 | early B-cell factor 3 | 0.460 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.453 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.452 | |
| Dock1 | dedicator of cytokinesis 1 | 0.451 | |
| Hhex | hematopoietically expressed homeobox | 0.432 | |
| Alx3 | aristaless-like homeobox 3 | 0.425 | |
| Alx4 | aristaless-like homeobox 4 | 0.419 | |
| Rasip1 | Ras interacting protein 1 | 0.416 | |
| Prrx2 | paired related homeobox 2 | 0.415 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.413 | |
| Lhx5 | LIM homeobox protein 5 | 0.408 | |
| Cldn5 | claudin 5 | 0.405 | |
| Meox1 | mesenchyme homeobox 1 | 0.404 | |
| Sall3 | sal-like 3 (Drosophila) | 0.397 | |
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.396 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| JAG1 | jagged 1 | 1.000 | |
| NOTCH1 | notch 1 | 0.998 | |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.997 | |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.994 | |
| TGFB1 | transforming growth factor, beta 1 | 0.992 | |
| NOTCH3 | notch 3 | 0.981 | |
| BMP2 | bone morphogenetic protein 2 | 0.950 | |
| ACVR1 | activin A receptor, type I | 0.913 | |
| SMAD7 | SMAD family member 7 | 0.910 | |
| GDF5 | growth differentiation factor 5 | 0.909 | |
| ENG | endoglin | 0.879 | |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.848 | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.562 | |
| TGFB3 | transforming growth factor, beta 3 | 0.526 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.509 | |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.493 | |
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.461 | |
| DLL1 | delta-like 1 (Drosophila) | 0.414 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.280 | |
| FSTL1 | follistatin-like 1 | 0.272 | |
| SMAD2 | SMAD family member 2 | 0.260 | |
| XIAP | X-linked inhibitor of apoptosis | 0.237 | |
| MAML1 | mastermind-like 1 (Drosophila) | 0.145 | |
| JAG2 | jagged 2 | 0.144 | |
| PDGFC | platelet derived growth factor C | 0.134 | |
| RXRA | retinoid X receptor, alpha | 0.128 | |
| MAPK8 | mitogen-activated protein kinase 8 | 0.127 | |
| NOTCH2 | notch 2 | 0.115 | |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.104 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.072 | |
| SMAD1 | SMAD family member 1 | 0.060 | |
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.057 | |
| NRP1 | neuropilin 1 | 0.056 | |
| MARCKSL1 | MARCKS-like 1 | 0.041 | |
| BMP4 | bone morphogenetic protein 4 | 0.035 | |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.034 | |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | 0.025 | |
| NOTCH2NL | notch 2 N-terminal like | 0.025 | |
| FNDC3B | fibronectin type III domain containing 3B | 0.022 | |
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.022 | |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.021 | |
| CTBP2 | C-terminal binding protein 2 | 0.021 | |
| GSK3B | glycogen synthase kinase 3 beta | 0.020 | |
| SMAD4 | SMAD family member 4 | 0.018 | |
| EGFL7 | EGF-like-domain, multiple 7 | 0.018 | |
| ACVR1B | activin A receptor, type IB | 0.017 | |
| SMAD6 | SMAD family member 6 | 0.017 | |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.016 | |
| GFI1B | growth factor independent 1B transcription repressor | 0.013 | |
| ANTXR2 | anthrax toxin receptor 2 | 0.013 | |
| RAMP2 | receptor (G protein-coupled) activity modifying protein 2 | 0.012 | |
| ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.012 | |
| EFNB2 | ephrin-B2 | 0.012 | |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.011 | |
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.010 | |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.010 | |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.010 | |
| AXIN1 | axin 1 | 0.010 |