The network for 'regulation of granulocyte chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of granulocyte chemotaxis

Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.

Mus musculus
Name Description Probability Func Analog Organism
Cd44 CD44 antigen 0.853
Ccr2 chemokine (C-C motif) receptor 2 0.779
Selp selectin, platelet 0.761
Ccr1 chemokine (C-C motif) receptor 1 0.614
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.487
Ccl2 chemokine (C-C motif) ligand 2 0.443
C3ar1 complement component 3a receptor 1 0.442
Il1b interleukin 1 beta 0.396
Cxcr2 chemokine (C-X-C motif) receptor 2 0.377
Msr1 macrophage scavenger receptor 1 0.363
Ccl3 chemokine (C-C motif) ligand 3 0.304
Itgax integrin alpha X 0.271
Ccl4 chemokine (C-C motif) ligand 4 0.182
Lyz2 lysozyme 2 0.171
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.167
Fcgr1 Fc receptor, IgG, high affinity I 0.165
H2-Eb1 histocompatibility 2, class II antigen E beta 0.153
Rac1 RAS-related C3 botulinum substrate 1 0.144
Slfn1 schlafen 1 0.141
Mmp8 matrix metallopeptidase 8 0.134
Csf1 colony stimulating factor 1 (macrophage) 0.113
Ccl8 chemokine (C-C motif) ligand 8 0.109
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.106
Ccl6 chemokine (C-C motif) ligand 6 0.104
Itgb2 integrin beta 2 0.094
Il12b interleukin 12b 0.091
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.091
Il10ra interleukin 10 receptor, alpha 0.085
Ccr5 chemokine (C-C motif) receptor 5 0.085
Cxcl13 chemokine (C-X-C motif) ligand 13 0.084
Sele selectin, endothelial cell 0.077
Sfpi1 SFFV proviral integration 1 0.074
Slit3 slit homolog 3 (Drosophila) 0.074
Ccl7 chemokine (C-C motif) ligand 7 0.073
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.073
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.072
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.072
Xcr1 chemokine (C motif) receptor 1 0.071
Cdh5 cadherin 5 0.070
Cd7 CD7 antigen 0.069
Ear2 eosinophil-associated, ribonuclease A family, member 2 0.069
Has1 hyaluronan synthase1 0.069
Cd180 CD180 antigen 0.068
Il18rap interleukin 18 receptor accessory protein 0.068
Il2rb interleukin 2 receptor, beta chain 0.068
Osmr oncostatin M receptor 0.067
Clec4d C-type lectin domain family 4, member d 0.067
Gzma granzyme A 0.067
Slc10a6 solute carrier family 10 (sodium/bile acid cotransporter family), member 6 0.066
Il1rn interleukin 1 receptor antagonist 0.066
S100a9 S100 calcium binding protein A9 (calgranulin B) 0.066
Folr2 folate receptor 2 (fetal) 0.065
Selplg selectin, platelet (p-selectin) ligand 0.062
Fpr2 formyl peptide receptor 2 0.061
Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N 0.059
Ifitm6 interferon induced transmembrane protein 6 0.058
Cxcl2 chemokine (C-X-C motif) ligand 2 0.057
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.056
Robo1 roundabout homolog 1 (Drosophila) 0.056
AF251705 cDNA sequence AF251705 0.056
H2-Ab1 histocompatibility 2, class II antigen A, beta 1 0.056
Il1r1 interleukin 1 receptor, type I 0.054
Lin7c lin-7 homolog C (C. elegans) 0.053
Lilrb3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.053
Batf basic leucine zipper transcription factor, ATF-like 0.053
Il1a interleukin 1 alpha 0.052
Itgam integrin alpha M 0.051
Mmp12 matrix metallopeptidase 12 0.051
Gm14548 predicted gene 14548 0.049
Ccl12 chemokine (C-C motif) ligand 12 0.048
Tnf tumor necrosis factor 0.046
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.046
Mrpl3 mitochondrial ribosomal protein L3 0.045
Cxcl12 chemokine (C-X-C motif) ligand 12 0.045
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.044
Icam1 intercellular adhesion molecule 1 0.042
Ctsw cathepsin W 0.041
Itgal integrin alpha L 0.039
Gpr132 G protein-coupled receptor 132 0.038
Cybb cytochrome b-245, beta polypeptide 0.038
Chi3l3 chitinase 3-like 3 0.038
Fpr1 formyl peptide receptor 1 0.037
Bdkrb1 bradykinin receptor, beta 1 0.037
Hp haptoglobin 0.036
Il18r1 interleukin 18 receptor 1 0.036
Cd14 CD14 antigen 0.035
Slfn4 schlafen 4 0.035
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.035
Myo1f myosin IF 0.034
Fcer2a Fc receptor, IgE, low affinity II, alpha polypeptide 0.033
Ngp neutrophilic granule protein 0.032
Ush1c Usher syndrome 1C homolog (human) 0.032
Tyrobp TYRO protein tyrosine kinase binding protein 0.032
Mmp3 matrix metallopeptidase 3 0.032
Ccl9 chemokine (C-C motif) ligand 9 0.032
Cd96 CD96 antigen 0.031
Tbxas1 thromboxane A synthase 1, platelet 0.030
Prg3 proteoglycan 3 0.030
Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 0.030
Ncr1 natural cytotoxicity triggering receptor 1 0.029
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
cdh5 cadherin 5 0.092
etv2 ets variant gene 2 0.079
bmp4 bone morphogenetic protein 4 0.044
LOC557072 caspase recruitment domain-containing protein 11-like 0.033
erg v-ets erythroblastosis virus E26 oncogene like (avian) 0.033
tie2 endothelium-specific receptor tyrosine kinase 2 0.027
plxnd1 plexin D1 0.026
postn periostin, osteoblast specific factor 0.024
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.020
dll4 delta-like 4 (Drosophila) 0.019
tie1 endothelium-specific receptor tyrosine kinase 1 0.018
osr1 odd-skipped related 1 (Drosophila) 0.017
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.017
card9 caspase recruitment domain family, member 9 0.016
vegfc vascular endothelial growth factor c 0.013
krml2.2 Kreisler (mouse) maf-related leucine zipper homolog 2.2 0.013
cmyb transcription factor cmyb 0.012
nipblb novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila) 0.012
cxcl12b chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) 0.011
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.011
ptprf protein tyrosine phosphatase, receptor type, F 0.010
jam2a junctional adhesion molecule 2a 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 0.997
CCL5 chemokine (C-C motif) ligand 5 0.997
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.925
CXCL9 chemokine (C-X-C motif) ligand 9 0.872
S100B S100 calcium binding protein B 0.868
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.847
S100A1 S100 calcium binding protein A1 0.771
S100A16 S100 calcium binding protein A16 0.767
S100A14 S100 calcium binding protein A14 0.734
DPP4 dipeptidyl-peptidase 4 0.538
CCL2 chemokine (C-C motif) ligand 2 0.452
S100A6 S100 calcium binding protein A6 0.447
NCF2 neutrophil cytosolic factor 2 0.440
CCR7 chemokine (C-C motif) receptor 7 0.416
IL8 interleukin 8 0.411
CXCL10 chemokine (C-X-C motif) ligand 10 0.384
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.349
CXCR4 chemokine (C-X-C motif) receptor 4 0.343
IL6 interleukin 6 (interferon, beta 2) 0.331
CCL19 chemokine (C-C motif) ligand 19 0.325
CCL22 chemokine (C-C motif) ligand 22 0.281
CCL13 chemokine (C-C motif) ligand 13 0.244
IFNG interferon, gamma 0.237
CCL8 chemokine (C-C motif) ligand 8 0.237
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.224
IL2RG interleukin 2 receptor, gamma 0.214
IL1B interleukin 1, beta 0.210
IL2RB interleukin 2 receptor, beta 0.197
CCR1 chemokine (C-C motif) receptor 1 0.181
CXCL13 chemokine (C-X-C motif) ligand 13 0.171
TLR4 toll-like receptor 4 0.170
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.159
PARD3 par-3 partitioning defective 3 homolog (C. elegans) 0.155
CCL7 chemokine (C-C motif) ligand 7 0.149
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.133
CCL11 chemokine (C-C motif) ligand 11 0.117
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.115
CXCL11 chemokine (C-X-C motif) ligand 11 0.105
CCR4 chemokine (C-C motif) receptor 4 0.103
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.096
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.084
CCL4 chemokine (C-C motif) ligand 4 0.083
IL7R interleukin 7 receptor 0.083
PLEK pleckstrin 0.080
CD93 CD93 molecule 0.076
CCL20 chemokine (C-C motif) ligand 20 0.076
C1QA complement component 1, q subcomponent, A chain 0.073
IL10 interleukin 10 0.069
FPR1 formyl peptide receptor 1 0.064
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.063
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.063
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.062
C5AR1 complement component 5a receptor 1 0.056
EZR ezrin 0.050
PLAUR plasminogen activator, urokinase receptor 0.050
TNF tumor necrosis factor 0.049
TGFB1 transforming growth factor, beta 1 0.049
CXCL2 chemokine (C-X-C motif) ligand 2 0.048
CCR2 chemokine (C-C motif) receptor 2 0.046
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.045
GZMK granzyme K (granzyme 3; tryptase II) 0.045
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.043
JAM3 junctional adhesion molecule 3 0.043
CCL3 chemokine (C-C motif) ligand 3 0.041
JAM2 junctional adhesion molecule 2 0.040
SELL selectin L 0.040
IL1R2 interleukin 1 receptor, type II 0.040
VCAN versican 0.039
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.037
IL1RN interleukin 1 receptor antagonist 0.037
CD163 CD163 molecule 0.036
CYBB cytochrome b-245, beta polypeptide 0.036
TREM1 triggering receptor expressed on myeloid cells 1 0.033
CLEC7A C-type lectin domain family 7, member A 0.032
AGER advanced glycosylation end product-specific receptor 0.031
CXCL3 chemokine (C-X-C motif) ligand 3 0.030
SELE selectin E 0.030
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.029
FYN FYN oncogene related to SRC, FGR, YES 0.029
IL1R1 interleukin 1 receptor, type I 0.028
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.028
CLEC4A C-type lectin domain family 4, member A 0.027
VCAM1 vascular cell adhesion molecule 1 0.027
IL16 interleukin 16 (lymphocyte chemoattractant factor) 0.027
SFRP4 secreted frizzled-related protein 4 0.026
RHOA ras homolog gene family, member A 0.026
RGS1 regulator of G-protein signaling 1 0.026
BCL2A1 BCL2-related protein A1 0.026
RHOC ras homolog gene family, member C 0.026
TLR2 toll-like receptor 2 0.025
FKBP4 FK506 binding protein 4, 59kDa 0.025
SRGN serglycin 0.025
S100P S100 calcium binding protein P 0.025
CXCL5 chemokine (C-X-C motif) ligand 5 0.024
AREG amphiregulin 0.024
BAK1 BCL2-antagonist/killer 1 0.024
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.024
AQP9 aquaporin 9 0.023
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.022
CD40LG CD40 ligand 0.022
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Tcrb T-cell receptor beta chain 0.299
RT1-Ba RT1 class II, locus Ba 0.108
Il2rb interleukin 2 receptor, beta 0.084
Il2rg interleukin 2 receptor, gamma 0.082
Cxcl10 chemokine (C-X-C motif) ligand 10 0.059
Cd86 CD86 molecule 0.054
Ccl4 chemokine (C-C motif) ligand 4 0.044
Ptger4 prostaglandin E receptor 4 (subtype EP4) 0.040
Psp parotid secretory protein 0.030
RT1-Bb RT1 class II, locus Bb 0.026
Neurl3 neuralized homolog 3 (Drosophila) 0.026
Cxcl2 chemokine (C-X-C motif) ligand 2 0.018
Il6 interleukin 6 0.018
Prss1 protease, serine, 1 (trypsin 1) 0.016
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.016
Ccl20 chemokine (C-C motif) ligand 20 0.015
RT1-Da RT1 class II, locus Da 0.015
Fam65b family with sequence similarity 65, member B 0.015
Ccl3 chemokine (C-C motif) ligand 3 0.014
Gzmk granzyme K 0.014
Cd8a CD8a molecule 0.013
RT1-Db1 RT1 class II, locus Db1 0.013
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.013
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.012
Cd14 CD14 molecule 0.012
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.012
Cd69 Cd69 molecule 0.011
Dmbt1 deleted in malignant brain tumors 1 0.011
Cpa3 carboxypeptidase A3, mast cell 0.011
Il1a interleukin 1 alpha 0.011
Kcna3 potassium voltage-gated channel, shaker-related subfamily, member 3 0.011
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.011
Ccr2 chemokine (C-C motif) receptor 2 0.010
Ccl7 chemokine (C-C motif) ligand 7 0.010
Ccr5 chemokine (C-C motif) receptor 5 0.010
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.010
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism