IMP

Process View

Homo sapiens

32 genes annotated in human

Multi-species View

regulation of steroid metabolic process

GO:0019218

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of steroid metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of steroid metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	0.998	Human
FGF1	fibroblast growth factor 1 (acidic)	0.882
FGFR1	fibroblast growth factor receptor 1	0.858	Human
HNF4A	hepatocyte nuclear factor 4, alpha	0.826
IL1R1	interleukin 1 receptor, type I	0.815
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.713
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	0.705	Human
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.680	Human
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.676
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.642	Human
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.592
INSR	insulin receptor	0.468
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.430	Yeast
CREBBP	CREB binding protein	0.415
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.387
ZFYVE9	zinc finger, FYVE domain containing 9	0.341
FGF10	fibroblast growth factor 10	0.314	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.313
GH1	growth hormone 1	0.295	Rat
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.292
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.291
BCL3	B-cell CLL/lymphoma 3	0.252
CSH1	chorionic somatomammotropin hormone 1 (placental lactogen)	0.251	Rat
NCOR2	nuclear receptor corepressor 2	0.242
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.223	Human
NCOA1	nuclear receptor coactivator 1	0.205
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.200
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.197
ALB	albumin	0.192
SREBF2	sterol regulatory element binding transcription factor 2	0.186
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.156
CSHL1	chorionic somatomammotropin hormone-like 1	0.151	Rat
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.149	Human
TNIP1	TNFAIP3 interacting protein 1	0.145
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.143	Human
EP300	E1A binding protein p300	0.136
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.133	Yeast
FGF8	fibroblast growth factor 8 (androgen-induced)	0.125
GH2	growth hormone 2	0.110	Rat
APOC2	apolipoprotein C-II	0.095
ESR1	estrogen receptor 1	0.094
BMPR1B	bone morphogenetic protein receptor, type IB	0.084
CSH2	chorionic somatomammotropin hormone 2	0.084	Rat
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.082
KLB	klotho beta	0.073
PGRMC1	progesterone receptor membrane component 1	0.069
FGF7	fibroblast growth factor 7	0.068	Human
MED15	mediator complex subunit 15	0.067
FGF2	fibroblast growth factor 2 (basic)	0.064	Human
APOC1	apolipoprotein C-I	0.062
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.060
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.059
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.055
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.050
IRS1	insulin receptor substrate 1	0.048
RRAGC	Ras-related GTP binding C	0.046
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.046	Yeast
RXRA	retinoid X receptor, alpha	0.045
SKIL	SKI-like oncogene	0.044
MYO6	myosin VI	0.044
RUNX1	runt-related transcription factor 1	0.043
SMAD3	SMAD family member 3	0.042
IL2RB	interleukin 2 receptor, beta	0.041
HDAC3	histone deacetylase 3	0.040
SF3B4	splicing factor 3b, subunit 4, 49kDa	0.040
HP	haptoglobin	0.040
HR	hairless homolog (mouse)	0.040
RLN3	relaxin 3	0.039
TIMP3	TIMP metallopeptidase inhibitor 3	0.039
ITGB1BP3	integrin beta 1 binding protein 3	0.038
WNT1	wingless-type MMTV integration site family, member 1	0.038	Human
APOC3	apolipoprotein C-III	0.037
LDLR	low density lipoprotein receptor	0.035
ZMYND11	zinc finger, MYND-type containing 11	0.034
SMAD6	SMAD family member 6	0.034
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.034
GRB10	growth factor receptor-bound protein 10	0.034
FRS2	fibroblast growth factor receptor substrate 2	0.033
FGF4	fibroblast growth factor 4	0.033	Human
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.032
ACAA1	acetyl-CoA acyltransferase 1	0.031
LAMTOR2	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2	0.031
RRAGA	Ras-related GTP binding A	0.031
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.030
FBXL15	F-box and leucine-rich repeat protein 15	0.030
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.029	Yeast
SP1	Sp1 transcription factor	0.029
FGF18	fibroblast growth factor 18	0.028
PPARA	peroxisome proliferator-activated receptor alpha	0.028	Human
C7orf59	chromosome 7 open reading frame 59	0.027
PGR	progesterone receptor	0.027
DECR1	2,4-dienoyl CoA reductase 1, mitochondrial	0.027
FSTL1	follistatin-like 1	0.027
CAV1	caveolin 1, caveolae protein, 22kDa	0.026
TG	thyroglobulin	0.026
IRS2	insulin receptor substrate 2	0.026
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.025
CXXC5	CXXC finger protein 5	0.025
SNW1	SNW domain containing 1	0.025
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.025	Yeast
CYP19A1	cytochrome P450, family 19, subfamily A, polypeptide 1	0.025
IHH	Indian hedgehog	0.025
PEX19	peroxisomal biogenesis factor 19	0.024
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.024
ABCF3	ATP-binding cassette, sub-family F (GCN20), member 3	0.024
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.024
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.024
AHSG	alpha-2-HS-glycoprotein	0.024
KAT2B	K(lysine) acetyltransferase 2B	0.023
AMBP	alpha-1-microglobulin/bikunin precursor	0.023
F7	coagulation factor VII (serum prothrombin conversion accelerator)	0.023
GHR	growth hormone receptor	0.023
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.023
LCAT	lecithin-cholesterol acyltransferase	0.023
SMAD2	SMAD family member 2	0.023
AR	androgen receptor	0.023
ITIH1	inter-alpha (globulin) inhibitor H1	0.022
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.022
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.022
SMAD7	SMAD family member 7	0.022
GGA3	golgi-associated, gamma adaptin ear containing, ARF binding protein 3	0.021
RBM4	RNA binding motif protein 4	0.021
SMN1	survival of motor neuron 1, telomeric	0.021
TF	transferrin	0.021
BAG1	BCL2-associated athanogene	0.021
IL1R2	interleukin 1 receptor, type II	0.021
ONECUT1	one cut homeobox 1	0.021
ZEB2	zinc finger E-box binding homeobox 2	0.021
ANKRD13A	ankyrin repeat domain 13A	0.020
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	0.020
NCOA6	nuclear receptor coactivator 6	0.020
DCN	decorin	0.020
SFRP1	secreted frizzled-related protein 1	0.019
HBXIP	hepatitis B virus x interacting protein	0.019
JAG2	jagged 2	0.019
NCOR1	nuclear receptor corepressor 1	0.019
LRP6	low density lipoprotein receptor-related protein 6	0.019
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.019
RARA	retinoic acid receptor, alpha	0.019
LOXL4	lysyl oxidase-like 4	0.019
PPARG	peroxisome proliferator-activated receptor gamma	0.018	Human
STAP2	signal transducing adaptor family member 2	0.018
A2M	alpha-2-macroglobulin	0.018
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.018
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.018
FGF19	fibroblast growth factor 19	0.018
CCL20	chemokine (C-C motif) ligand 20	0.017
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.017
PEX14	peroxisomal biogenesis factor 14	0.017
BHMT	betaine--homocysteine S-methyltransferase	0.017
GJB4	gap junction protein, beta 4, 30.3kDa	0.017
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.017
FST	follistatin	0.017
ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	0.017
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.016
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.016
RNF11	ring finger protein 11	0.016
EPAS1	endothelial PAS domain protein 1	0.016
GDNF	glial cell derived neurotrophic factor	0.016
NOG	noggin	0.016
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.016
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.016
HIPK2	homeodomain interacting protein kinase 2	0.016
WNT11	wingless-type MMTV integration site family, member 11	0.016	Human
WNT3	wingless-type MMTV integration site family, member 3	0.016	Human
SCD	stearoyl-CoA desaturase (delta-9-desaturase)	0.016
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.015
IGF2R	insulin-like growth factor 2 receptor	0.015
KNG1	kininogen 1	0.015
BDKRB1	bradykinin receptor B1	0.015	Human
HSD17B4	hydroxysteroid (17-beta) dehydrogenase 4	0.015
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.015
HAND1	heart and neural crest derivatives expressed 1	0.015
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.015
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.015
SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	0.015
SMAD4	SMAD family member 4	0.014
YY1	YY1 transcription factor	0.014
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.014
LHX3	LIM homeobox 3	0.014
NELL2	NEL-like 2 (chicken)	0.014
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.014	Human
FGA	fibrinogen alpha chain	0.014
SOX7	SRY (sex determining region Y)-box 7	0.014
FGF3	fibroblast growth factor 3	0.014	Human
IGFBP1	insulin-like growth factor binding protein 1	0.014
TM4SF5	transmembrane 4 L six family member 5	0.014
PTHLH	parathyroid hormone-like hormone	0.014
OTC	ornithine carbamoyltransferase	0.014
NKD2	naked cuticle homolog 2 (Drosophila)	0.014
CDX1	caudal type homeobox 1	0.014
ESRRG	estrogen-related receptor gamma	0.014
TRADD	TNFRSF1A-associated via death domain	0.014
CYP7B1	cytochrome P450, family 7, subfamily B, polypeptide 1	0.014	Human
LIPC	lipase, hepatic	0.014
JUB	jub, ajuba homolog (Xenopus laevis)	0.014
HRG	histidine-rich glycoprotein	0.014
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.014
SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	0.014
FBLN1	fibulin 1	0.014
COL2A1	collagen, type II, alpha 1	0.013
NOS1	nitric oxide synthase 1 (neuronal)	0.013
MAPT	microtubule-associated protein tau	0.013
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.013
AADAC	arylacetamide deacetylase (esterase)	0.013
PAX7	paired box 7	0.013
CSNK1D	casein kinase 1, delta	0.013
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.013
PRDM5	PR domain containing 5	0.013
HOXD1	homeobox D1	0.013
RCOR1	REST corepressor 1	0.013
EPS15	epidermal growth factor receptor pathway substrate 15	0.013
HPD	4-hydroxyphenylpyruvate dioxygenase	0.013
TNIP2	TNFAIP3 interacting protein 2	0.013
DMD	dystrophin	0.013
CCL1	chemokine (C-C motif) ligand 1	0.013
BMP4	bone morphogenetic protein 4	0.013	Human
SKP1	S-phase kinase-associated protein 1	0.013
PTEN	phosphatase and tensin homolog	0.013
SOX21	SRY (sex determining region Y)-box 21	0.013
TLX1	T-cell leukemia homeobox 1	0.013
CCRN4L	CCR4 carbon catabolite repression 4-like (S. cerevisiae)	0.013
THPO	thrombopoietin	0.013
SOCS1	suppressor of cytokine signaling 1	0.013
FOXA2	forkhead box A2	0.013	Mouse
GFER	growth factor, augmenter of liver regeneration	0.013
BARX1	BARX homeobox 1	0.013
RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1	0.013
NGF	nerve growth factor (beta polypeptide)	0.013
C8A	complement component 8, alpha polypeptide	0.013
SRP14	signal recognition particle 14kDa (homologous Alu RNA binding protein)	0.013
FOXF1	forkhead box F1	0.013
ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5	0.013
GSC	goosecoid homeobox	0.012
RAX	retina and anterior neural fold homeobox	0.012
CAT	catalase	0.012
BMP7	bone morphogenetic protein 7	0.012	Human
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.012
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.012
FZD10	frizzled homolog 10 (Drosophila)	0.012
PEX2	peroxisomal biogenesis factor 2	0.012	Mouse
RBMS3	RNA binding motif, single stranded interacting protein 3	0.012
WIF1	WNT inhibitory factor 1	0.012
GNG13	guanine nucleotide binding protein (G protein), gamma 13	0.012
COX6C	cytochrome c oxidase subunit VIc	0.012
CALCR	calcitonin receptor	0.012
TMPRSS6	transmembrane protease, serine 6	0.012
PGLYRP4	peptidoglycan recognition protein 4	0.012
PRRX2	paired related homeobox 2	0.012
TGFBR1	transforming growth factor, beta receptor 1	0.012
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.012
COL13A1	collagen, type XIII, alpha 1	0.012
HSD3B2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.012	Rat
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.012	Human
ACVR1B	activin A receptor, type IB	0.012
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	0.012
INHBA	inhibin, beta A	0.012
HOXB1	homeobox B1	0.012
ACAN	aggrecan	0.012
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.012
FOXO3	forkhead box O3	0.012
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.012
WNT4	wingless-type MMTV integration site family, member 4	0.012
CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	0.012	Human
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.012
TBX5	T-box 5	0.012
STAB2	stabilin 2	0.012
AGTR1	angiotensin II receptor, type 1	0.012
PTH1R	parathyroid hormone 1 receptor	0.012
CLDN14	claudin 14	0.012
TP73	tumor protein p73	0.011
PRDX1	peroxiredoxin 1	0.011
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.011
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.011
FGF5	fibroblast growth factor 5	0.011	Human
CRYZ	crystallin, zeta (quinone reductase)	0.011
WNT2	wingless-type MMTV integration site family member 2	0.011	Human
FGFR3	fibroblast growth factor receptor 3	0.011	Human
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.011
CTGF	connective tissue growth factor	0.011
NOTCH1	notch 1	0.011
F11	coagulation factor XI	0.011
CCR9	chemokine (C-C motif) receptor 9	0.011
KRT76	keratin 76	0.011
NEUROG2	neurogenin 2	0.011
DNAJC1	DnaJ (Hsp40) homolog, subfamily C, member 1	0.011
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.011
WNT9B	wingless-type MMTV integration site family, member 9B	0.011	Human
HYAL1	hyaluronoglucosaminidase 1	0.011
RGN	regucalcin (senescence marker protein-30)	0.011
C8B	complement component 8, beta polypeptide	0.011
KALRN	kalirin, RhoGEF kinase	0.011
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.011
PRKCQ	protein kinase C, theta	0.011
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.011
GLYAT	glycine-N-acyltransferase	0.011
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.011
PLTP	phospholipid transfer protein	0.011
KCNK9	potassium channel, subfamily K, member 9	0.011
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.011
OTP	orthopedia homeobox	0.011
PITX2	paired-like homeodomain 2	0.011
IRF4	interferon regulatory factor 4	0.011
PDE6A	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.011
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.011
GPC3	glypican 3	0.011
WT1	Wilms tumor 1	0.011
DTNA	dystrobrevin, alpha	0.011
PAH	phenylalanine hydroxylase	0.011
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.011
NTN1	netrin 1	0.011
PCSK9	proprotein convertase subtilisin/kexin type 9	0.010
ADH5	alcohol dehydrogenase 5 (class III), chi polypeptide	0.010
F2	coagulation factor II (thrombin)	0.010
AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.010
TOLLIP	toll interacting protein	0.010
HMGA2	high mobility group AT-hook 2	0.010
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.010
IDI1	isopentenyl-diphosphate delta isomerase 1	0.010
GEMIN5	gem (nuclear organelle) associated protein 5	0.010
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A	0.010
HRSP12	heat-responsive protein 12	0.010
PELP1	proline, glutamate and leucine rich protein 1	0.010
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.010
APOC4	apolipoprotein C-IV	0.010
ADRB3	adrenergic, beta-3-, receptor	0.010
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.010
FOXF2	forkhead box F2	0.010
MYOD1	myogenic differentiation 1	0.010
RNF168	ring finger protein 168	0.010
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.010	Human Mouse
SLC13A5	solute carrier family 13 (sodium-dependent citrate transporter), member 5	0.010
RBP4	retinol binding protein 4, plasma	0.010
NTNG1	netrin G1	0.010
WNK1	WNK lysine deficient protein kinase 1	0.010