IMP
Process View
negative regulation of mononuclear cell proliferation
Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of mononuclear cell proliferation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CD80 | CD80 molecule | 0.793 | ||
| HLA-B | major histocompatibility complex, class I, B | 0.401 | ||
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.385 | ||
| B2M | beta-2-microglobulin | 0.334 | ||
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.240 | ||
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 0.217 | ||
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 0.214 | ||
| HLA-F | major histocompatibility complex, class I, F | 0.165 | Human | |
| HLA-E | major histocompatibility complex, class I, E | 0.156 | Human | |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.143 | ||
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | 0.133 | ||
| IL1B | interleukin 1, beta | 0.113 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.098 | Human | |
| IL8 | interleukin 8 | 0.086 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.084 | Mouse | |
| HLA-G | major histocompatibility complex, class I, G | 0.080 | ||
| POU3F2 | POU class 3 homeobox 2 | 0.076 | ||
| GRAP2 | GRB2-related adaptor protein 2 | 0.075 | ||
| HLA-A | major histocompatibility complex, class I, A | 0.070 | Human | |
| ICAM1 | intercellular adhesion molecule 1 | 0.070 | ||
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 0.069 | Human | |
| CD86 | CD86 molecule | 0.068 | ||
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | 0.064 | ||
| IL10RA | interleukin 10 receptor, alpha | 0.063 | ||
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.052 | Human | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.048 | ||
| CD33 | CD33 molecule | 0.046 | ||
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.044 | ||
| HLA-C | major histocompatibility complex, class I, C | 0.040 | Human | |
| IL6 | interleukin 6 (interferon, beta 2) | 0.039 | ||
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 0.039 | Human | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.038 | ||
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.038 | ||
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.037 | ||
| SYK | spleen tyrosine kinase | 0.035 | ||
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.035 | ||
| TFF1 | trefoil factor 1 | 0.035 | ||
| HK3 | hexokinase 3 (white cell) | 0.034 | ||
| HLA-DRB5 | major histocompatibility complex, class II, DR beta 5 | 0.034 | Human | |
| IL4R | interleukin 4 receptor | 0.033 | ||
| SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.033 | ||
| PTAFR | platelet-activating factor receptor | 0.033 | ||
| POU5F1 | POU class 5 homeobox 1 | 0.033 | ||
| CCL22 | chemokine (C-C motif) ligand 22 | 0.033 | Human | |
| IL10 | interleukin 10 | 0.032 | ||
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.031 | Human | |
| AIF1 | allograft inflammatory factor 1 | 0.031 | ||
| ADAM17 | ADAM metallopeptidase domain 17 | 0.028 | ||
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.027 | ||
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 0.025 | ||
| EPOR | erythropoietin receptor | 0.025 | ||
| HLA-DMB | major histocompatibility complex, class II, DM beta | 0.025 | ||
| CD163 | CD163 molecule | 0.025 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.024 | ||
| APP | amyloid beta (A4) precursor protein | 0.024 | ||
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.024 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.023 | ||
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | 0.023 | Human Rat | |
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.023 | ||
| IL22RA1 | interleukin 22 receptor, alpha 1 | 0.022 | ||
| DPP4 | dipeptidyl-peptidase 4 | 0.022 | ||
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.022 | ||
| CCL7 | chemokine (C-C motif) ligand 7 | 0.021 | Human | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.021 | ||
| IGSF6 | immunoglobulin superfamily, member 6 | 0.021 | ||
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.020 | ||
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.020 | ||
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.018 | ||
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) | 0.018 | ||
| ENG | endoglin | 0.018 | ||
| CCL13 | chemokine (C-C motif) ligand 13 | 0.018 | Human | |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.017 | ||
| BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.017 | ||
| BTN3A1 | butyrophilin, subfamily 3, member A1 | 0.017 | ||
| BCL2A1 | BCL2-related protein A1 | 0.017 | ||
| IL22RA2 | interleukin 22 receptor, alpha 2 | 0.016 | ||
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.016 | ||
| NLRP3 | NLR family, pyrin domain containing 3 | 0.016 | ||
| IL1RN | interleukin 1 receptor antagonist | 0.016 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.016 | ||
| CCL20 | chemokine (C-C motif) ligand 20 | 0.016 | Human | |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.016 | ||
| PECAM1 | platelet/endothelial cell adhesion molecule | 0.016 | ||
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.015 | ||
| CCL2 | chemokine (C-C motif) ligand 2 | 0.015 | Human | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.014 | Human | |
| BTN3A2 | butyrophilin, subfamily 3, member A2 | 0.014 | ||
| HCK | hemopoietic cell kinase | 0.014 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.014 | ||
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.014 | ||
| PLEK | pleckstrin | 0.014 | ||
| TAPBP | TAP binding protein (tapasin) | 0.014 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.014 | ||
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.014 | ||
| TRAF5 | TNF receptor-associated factor 5 | 0.014 | ||
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.013 | ||
| SMAD7 | SMAD family member 7 | 0.013 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.013 | ||
| CCR4 | chemokine (C-C motif) receptor 4 | 0.013 | ||
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.013 | ||
| IFNG | interferon, gamma | 0.013 | ||
| SPI1 | spleen focus forming virus (SFFV) proviral integration oncogene spi1 | 0.012 | ||
| SH3BP2 | SH3-domain binding protein 2 | 0.012 | ||
| FPR3 | formyl peptide receptor 3 | 0.012 | ||
| TNF | tumor necrosis factor | 0.012 | ||
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.012 | ||
| XIAP | X-linked inhibitor of apoptosis | 0.012 | ||
| CCR5 | chemokine (C-C motif) receptor 5 | 0.011 | ||
| CCND1 | cyclin D1 | 0.011 | ||
| CCL5 | chemokine (C-C motif) ligand 5 | 0.011 | Human | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.011 | ||
| PBK | PDZ binding kinase | 0.011 | ||
| CD83 | CD83 molecule | 0.011 | ||
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.011 | ||
| CCR7 | chemokine (C-C motif) receptor 7 | 0.011 | ||
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | 0.011 | ||
| HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 | 0.010 | ||
| CCL11 | chemokine (C-C motif) ligand 11 | 0.010 | Human | |
| SOCS3 | suppressor of cytokine signaling 3 | 0.010 | ||
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.010 | ||
| CH25H | cholesterol 25-hydroxylase | 0.010 | ||
| BTN2A2 | butyrophilin, subfamily 2, member A2 | 0.010 | Mouse |