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Process View

Homo sapiens

24 genes annotated in human

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mrna 3 end processing

GO:0031124

Any process involved in forming the mature 3' end of an mRNA molecule.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mrna 3 end processing"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mrna 3 end processing" (in gray)

Name	Description	Probability	Func Analog Organism
TNRC6A	trinucleotide repeat containing 6A	1.000	Human
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	1.000
YBX1	Y box binding protein 1	1.000	Zebrafish
TOB1	transducer of ERBB2, 1	0.999
PABPC1	poly(A) binding protein, cytoplasmic 1	0.998	Yeast Mouse
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.997
WWOX	WW domain containing oxidoreductase	0.992
CNOT7	CCR4-NOT transcription complex, subunit 7	0.991
CNOT8	CCR4-NOT transcription complex, subunit 8	0.988	Human Fly
CPSF2	cleavage and polyadenylation specific factor 2, 100kDa	0.986
THOC4	THO complex 4	0.976
CTR9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.966	Yeast
DDX39B	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	0.914	Yeast
BTG1	B-cell translocation gene 1, anti-proliferative	0.848	Human
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.798
DICER1	dicer 1, ribonuclease type III	0.778
PRKCZ	protein kinase C, zeta	0.776	Yeast
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.708	Yeast
TNRC6B	trinucleotide repeat containing 6B	0.684
MNAT1	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)	0.677
DUSP1	dual specificity phosphatase 1	0.622
ZNF202	zinc finger protein 202	0.618
CPSF3	cleavage and polyadenylation specific factor 3, 73kDa	0.601
THOC5	THO complex 5	0.589
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.557
WDR61	WD repeat domain 61	0.556
CNOT2	CCR4-NOT transcription complex, subunit 2	0.534
CNOT1	CCR4-NOT transcription complex, subunit 1	0.513
PAIP2	poly(A) binding protein interacting protein 2	0.500
EIF2C4	eukaryotic translation initiation factor 2C, 4	0.461
CNOT6	CCR4-NOT transcription complex, subunit 6	0.416	Yeast Fly
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.412
NOXA1	NADPH oxidase activator 1	0.405
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.379
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.368
CNOT3	CCR4-NOT transcription complex, subunit 3	0.319	Yeast
PAN3	PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)	0.284	Yeast
PRRC2A	proline-rich coiled-coil 2A	0.265
TNRC6C	trinucleotide repeat containing 6C	0.243
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.229	Mouse
BTG2	BTG family, member 2	0.223
RAD21	RAD21 homolog (S. pombe)	0.213
CNOT10	CCR4-NOT transcription complex, subunit 10	0.199
CLK2	CDC-like kinase 2	0.195
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.195
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.192
CPEB4	cytoplasmic polyadenylation element binding protein 4	0.189	Human
ILF3	interleukin enhancer binding factor 3, 90kDa	0.185
SRPK2	SRSF protein kinase 2	0.176
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.162	Yeast
CPSF1	cleavage and polyadenylation specific factor 1, 160kDa	0.161
EIF4A3	eukaryotic translation initiation factor 4A3	0.152
RBM8A	RNA binding motif protein 8A	0.150
CNOT6L	CCR4-NOT transcription complex, subunit 6-like	0.121	Yeast
CPSF6	cleavage and polyadenylation specific factor 6, 68kDa	0.112
ACIN1	apoptotic chromatin condensation inducer 1	0.110
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.109
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.108
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.097
AEBP2	AE binding protein 2	0.096
CKS2	CDC28 protein kinase regulatory subunit 2	0.095
PTBP1	polypyrimidine tract binding protein 1	0.084
NXT1	NTF2-like export factor 1	0.083
CSTF2	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa	0.082
ANAPC4	anaphase promoting complex subunit 4	0.082
SYMPK	symplekin	0.081
FYN	FYN oncogene related to SRC, FGR, YES	0.077
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.075
CCNH	cyclin H	0.075
DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A	0.075	Yeast
CHTOP	chromatin target of PRMT1	0.073
ILF2	interleukin enhancer binding factor 2, 45kDa	0.072
MAPT	microtubule-associated protein tau	0.068
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.068
SRSF9	serine/arginine-rich splicing factor 9	0.067
CARD11	caspase recruitment domain family, member 11	0.066
TCEA1	transcription elongation factor A (SII), 1	0.062	Yeast
STAG2	stromal antigen 2	0.058
UBAP2L	ubiquitin associated protein 2-like	0.057
ZMAT3	zinc finger, matrin-type 3	0.056
THOC1	THO complex 1	0.055
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.055
CPEB3	cytoplasmic polyadenylation element binding protein 3	0.055
HSF1	heat shock transcription factor 1	0.055
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.052
CBWD2	COBW domain containing 2	0.051
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.051
MAGEA11	melanoma antigen family A, 11	0.045
PNRC1	proline-rich nuclear receptor coactivator 1	0.045
EIF2C3	eukaryotic translation initiation factor 2C, 3	0.044
LSM3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.044
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	0.043
TRIM41	tripartite motif containing 41	0.041
CCL14	chemokine (C-C motif) ligand 14	0.041
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.040
THOC2	THO complex 2	0.040
SH3RF1	SH3 domain containing ring finger 1	0.039
CIZ1	CDKN1A interacting zinc finger protein 1	0.038
KLF4	Kruppel-like factor 4 (gut)	0.037
PMS2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	0.037
CDCP1	CUB domain containing protein 1	0.035
PAN2	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)	0.035	Yeast Fly
XRN2	5'-3' exoribonuclease 2	0.035
GABARAPL1	GABA(A) receptor-associated protein like 1	0.034
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.032
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.031
SBF1	SET binding factor 1	0.031
POLR2J	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa	0.031
STRN4	striatin, calmodulin binding protein 4	0.030
KHSRP	KH-type splicing regulatory protein	0.029
DCAF15	DDB1 and CUL4 associated factor 15	0.029
NUP214	nucleoporin 214kDa	0.028
SNRPA	small nuclear ribonucleoprotein polypeptide A	0.028
CENPT	centromere protein T	0.028
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.027
CSNK1G2	casein kinase 1, gamma 2	0.027
THOC6	THO complex 6 homolog (Drosophila)	0.027
NUMB	numb homolog (Drosophila)	0.027
NUP35	nucleoporin 35kDa	0.027
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.026
MTA1	metastasis associated 1	0.026
IRF3	interferon regulatory factor 3	0.026
CELF1	CUGBP, Elav-like family member 1	0.025
ATAD2	ATPase family, AAA domain containing 2	0.025
ARID1A	AT rich interactive domain 1A (SWI-like)	0.025
FAM118B	family with sequence similarity 118, member B	0.025
ZC3HC1	zinc finger, C3HC-type containing 1	0.024
NCBP1	nuclear cap binding protein subunit 1, 80kDa	0.023
IPO8	importin 8	0.022
PAFAH1B2	platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)	0.022
PCBP1	poly(rC) binding protein 1	0.021
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.021
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.021
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.021
RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)	0.021
C1orf93	chromosome 1 open reading frame 93	0.020
NONO	non-POU domain containing, octamer-binding	0.019
TSC22D1	TSC22 domain family, member 1	0.019
PCBP2	poly(rC) binding protein 2	0.019
PRKCB	protein kinase C, beta	0.019
SARNP	SAP domain containing ribonucleoprotein	0.019
PTGES3	prostaglandin E synthase 3 (cytosolic)	0.018
DDX46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.018
MARK3	MAP/microtubule affinity-regulating kinase 3	0.018
MAGED2	melanoma antigen family D, 2	0.018
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.018
JUNB	jun B proto-oncogene	0.018
NCBP2	nuclear cap binding protein subunit 2, 20kDa	0.018
JUND	jun D proto-oncogene	0.018
C17orf85	chromosome 17 open reading frame 85	0.017
HMGN2	high mobility group nucleosomal binding domain 2	0.017
PCNA	proliferating cell nuclear antigen	0.017
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.017
FAM190B	family with sequence similarity 190, member B	0.017
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.016
MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)	0.016
CAPRIN1	cell cycle associated protein 1	0.016
SUGP1	SURP and G patch domain containing 1	0.016
PNN	pinin, desmosome associated protein	0.016
ASXL1	additional sex combs like 1 (Drosophila)	0.016
RAE1	RAE1 RNA export 1 homolog (S. pombe)	0.016
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.016
TOB2	transducer of ERBB2, 2	0.015
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.015
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.015
DAZAP1	DAZ associated protein 1	0.015
EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	0.015
SRRT	serrate RNA effector molecule homolog (Arabidopsis)	0.015
C7orf64	chromosome 7 open reading frame 64	0.015
GLIS2	GLIS family zinc finger 2	0.015
DAP3	death associated protein 3	0.014
TMSB4X	thymosin beta 4, X-linked	0.014
PAIP1	poly(A) binding protein interacting protein 1	0.014
ERI1	exoribonuclease 1	0.014
LMO3	LIM domain only 3 (rhombotin-like 2)	0.014
PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)	0.014	Yeast
GTF2H2	general transcription factor IIH, polypeptide 2, 44kDa	0.014
NUDT21	nudix (nucleoside diphosphate linked moiety X)-type motif 21	0.013
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.013
C19orf29	chromosome 19 open reading frame 29	0.013
CCND3	cyclin D3	0.013
NCF1	neutrophil cytosolic factor 1	0.013
ATXN1	ataxin 1	0.013
POLDIP3	polymerase (DNA-directed), delta interacting protein 3	0.012
MKNK2	MAP kinase interacting serine/threonine kinase 2	0.012
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.012
KLHL12	kelch-like 12 (Drosophila)	0.012
TARDBP	TAR DNA binding protein	0.011
CDK10	cyclin-dependent kinase 10	0.011
FBXO33	F-box protein 33	0.011
CKAP5	cytoskeleton associated protein 5	0.011
CCDC115	coiled-coil domain containing 115	0.011
DPY30	dpy-30 homolog (C. elegans)	0.011
CABIN1	calcineurin binding protein 1	0.011
CCHCR1	coiled-coil alpha-helical rod protein 1	0.011
NUP98	nucleoporin 98kDa	0.011
SESN2	sestrin 2	0.011
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.011
RBM41	RNA binding motif protein 41	0.011
HMGA1	high mobility group AT-hook 1	0.011
C5orf41	chromosome 5 open reading frame 41	0.011
MAPK14	mitogen-activated protein kinase 14	0.011
BACE1	beta-site APP-cleaving enzyme 1	0.011
SMG1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)	0.010
SERBP1	SERPINE1 mRNA binding protein 1	0.010
SMARCAD1	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1	0.010