IMP

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Homo sapiens

4 genes annotated in human

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histone serine phosphorylation

GO:0035404

The modification of histones by addition of a phosphate group to a serine residue.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "histone serine phosphorylation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "histone serine phosphorylation" (in gray)

Name	Description	Probability	Func Analog Organism
MAPK14	mitogen-activated protein kinase 14	0.993
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.922
INCENP	inner centromere protein antigens 135/155kDa	0.906
CDK1	cyclin-dependent kinase 1	0.860
BIRC5	baculoviral IAP repeat containing 5	0.852
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.831
AURKA	aurora kinase A	0.795	Mouse
MAPK1	mitogen-activated protein kinase 1	0.719
HTT	huntingtin	0.618
GAS2L3	growth arrest-specific 2 like 3	0.604
PLK1	polo-like kinase 1	0.573
MAPK3	mitogen-activated protein kinase 3	0.524
PRMT6	protein arginine methyltransferase 6	0.465
CDCA8	cell division cycle associated 8	0.365
COASY	CoA synthase	0.282
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.266
CDK2	cyclin-dependent kinase 2	0.241
GSK3B	glycogen synthase kinase 3 beta	0.225
RCC1	regulator of chromosome condensation 1	0.211
HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B	0.206
RNF19A	ring finger protein 19A	0.203
PTTG1	pituitary tumor-transforming 1	0.190
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.182
PIAS4	protein inhibitor of activated STAT, 4	0.181
RICTOR	RPTOR independent companion of MTOR, complex 2	0.174
EEF2K	eukaryotic elongation factor-2 kinase	0.170
CCNA2	cyclin A2	0.169
CDKN3	cyclin-dependent kinase inhibitor 3	0.165
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.165
MAPK8	mitogen-activated protein kinase 8	0.160
ACACA	acetyl-CoA carboxylase alpha	0.145
DUSP1	dual specificity phosphatase 1	0.137
TP53	tumor protein p53	0.136
NEK2	NIMA (never in mitosis gene a)-related kinase 2	0.126
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.123
CCDC101	coiled-coil domain containing 101	0.116
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.114
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.107
DUSP3	dual specificity phosphatase 3	0.088
SETD7	SET domain containing (lysine methyltransferase) 7	0.088
TTK	TTK protein kinase	0.087
C19orf46	chromosome 19 open reading frame 46	0.078
SGOL1	shugoshin-like 1 (S. pombe)	0.076
AURKB	aurora kinase B	0.074	Mouse
PDPK1	3-phosphoinositide dependent protein kinase-1	0.070
MAPT	microtubule-associated protein tau	0.068
ITSN1	intersectin 1 (SH3 domain protein)	0.063
CCNB2	cyclin B2	0.061
NCL	nucleolin	0.060
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.056
PRKCA	protein kinase C, alpha	0.055
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.055
UBE2C	ubiquitin-conjugating enzyme E2C	0.054
HMGB1	high mobility group box 1	0.054
CDC25C	cell division cycle 25 homolog C (S. pombe)	0.052
FZD5	frizzled homolog 5 (Drosophila)	0.051
MAP2K1	mitogen-activated protein kinase kinase 1	0.051
ING5	inhibitor of growth family, member 5	0.050
SMS	spermine synthase	0.050
KIF2C	kinesin family member 2C	0.043
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.042
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.042
DUSP7	dual specificity phosphatase 7	0.041
LMO4	LIM domain only 4	0.040
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.038
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.038
ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	0.038
C10orf116	chromosome 10 open reading frame 116	0.038
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.037
EP300	E1A binding protein p300	0.036
MPP1	membrane protein, palmitoylated 1, 55kDa	0.035
ZNF746	zinc finger protein 746	0.035
DHX34	DEAH (Asp-Glu-Ala-His) box polypeptide 34	0.034
GTSE1	G-2 and S-phase expressed 1	0.034
PTPRR	protein tyrosine phosphatase, receptor type, R	0.033
SMAD7	SMAD family member 7	0.032
FNIP1	folliculin interacting protein 1	0.032
HOXB7	homeobox B7	0.032
MAP2K4	mitogen-activated protein kinase kinase 4	0.030
VRK2	vaccinia related kinase 2	0.029	Human
CCNE1	cyclin E1	0.028
PSRC1	proline/serine-rich coiled-coil 1	0.028
MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.027
CDCA5	cell division cycle associated 5	0.027
TBCD	tubulin folding cofactor D	0.027
ILVBL	ilvB (bacterial acetolactate synthase)-like	0.026
CKS2	CDC28 protein kinase regulatory subunit 2	0.026
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.026
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.026
C6orf136	chromosome 6 open reading frame 136	0.026
PPID	peptidylprolyl isomerase D	0.025
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.025
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.024
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.024
MKNK1	MAP kinase interacting serine/threonine kinase 1	0.024
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.024	Mouse
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.023
EIF3C	eukaryotic translation initiation factor 3, subunit C	0.023
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.023
CLTC	clathrin, heavy chain (Hc)	0.021
MAGEH1	melanoma antigen family H, 1	0.021
ZNF71	zinc finger protein 71	0.021
GLMN	glomulin, FKBP associated protein	0.021
VASP	vasodilator-stimulated phosphoprotein	0.021
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.020
WASL	Wiskott-Aldrich syndrome-like	0.020
MAP2K3	mitogen-activated protein kinase kinase 3	0.020
NOTCH1	notch 1	0.019
POU2F1	POU class 2 homeobox 1	0.019
MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)	0.019
PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.018	Mouse
ACYP1	acylphosphatase 1, erythrocyte (common) type	0.018
TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.018
MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	0.017
ZNF512B	zinc finger protein 512B	0.017
MKNK2	MAP kinase interacting serine/threonine kinase 2	0.017
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.017
SMAD6	SMAD family member 6	0.017
IRF3	interferon regulatory factor 3	0.017
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.016
CPSF3L	cleavage and polyadenylation specific factor 3-like	0.016
HMGA1	high mobility group AT-hook 1	0.016	Human
HMGB2	high mobility group box 2	0.016
FMNL1	formin-like 1	0.016
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.015
SOS1	son of sevenless homolog 1 (Drosophila)	0.015
PICALM	phosphatidylinositol binding clathrin assembly protein	0.015
MBP	myelin basic protein	0.015
HDGF	hepatoma-derived growth factor	0.015
TROAP	trophinin associated protein (tastin)	0.015
KAT2B	K(lysine) acetyltransferase 2B	0.015
ATF2	activating transcription factor 2	0.015
SEPT1	septin 1	0.014
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.014
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.014
MAP2K6	mitogen-activated protein kinase kinase 6	0.014
MARK1	MAP/microtubule affinity-regulating kinase 1	0.014
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.014
QKI	quaking homolog, KH domain RNA binding (mouse)	0.014
TNPO1	transportin 1	0.014
DCTN1	dynactin 1	0.013
XPO7	exportin 7	0.013
RAB1B	RAB1B, member RAS oncogene family	0.013
EGR1	early growth response 1	0.013
UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	0.013
CLEC3B	C-type lectin domain family 3, member B	0.013
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.013
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.013
PTPN7	protein tyrosine phosphatase, non-receptor type 7	0.013
AKT1S1	AKT1 substrate 1 (proline-rich)	0.013
CDCA4	cell division cycle associated 4	0.013
ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)	0.013
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.013
RXRA	retinoid X receptor, alpha	0.013
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.013
GRK6	G protein-coupled receptor kinase 6	0.012
HNRNPL	heterogeneous nuclear ribonucleoprotein L	0.012
TP53BP2	tumor protein p53 binding protein, 2	0.012
ARHGAP9	Rho GTPase activating protein 9	0.012
RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	0.012	Human
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.012
FAM64A	family with sequence similarity 64, member A	0.012
GMNN	geminin, DNA replication inhibitor	0.012
CFL1	cofilin 1 (non-muscle)	0.012
SIRT1	sirtuin 1	0.011
RPTOR	regulatory associated protein of MTOR, complex 1	0.011
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.011
WRN	Werner syndrome, RecQ helicase-like	0.011
C13orf34	chromosome 13 open reading frame 34	0.011
RRAS2	related RAS viral (r-ras) oncogene homolog 2	0.011
AGFG1	ArfGAP with FG repeats 1	0.011
RACGAP1	Rac GTPase activating protein 1	0.011
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.011
SERGEF	secretion regulating guanine nucleotide exchange factor	0.011
KIF20A	kinesin family member 20A	0.011
MED25	mediator complex subunit 25	0.011
SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	0.011
FKBP5	FK506 binding protein 5	0.011
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.011
LYPLA2	lysophospholipase II	0.011
PPM1E	protein phosphatase, Mg2+/Mn2+ dependent, 1E	0.011
KIF23	kinesin family member 23	0.011
CDT1	chromatin licensing and DNA replication factor 1	0.011
DALRD3	DALR anticodon binding domain containing 3	0.010
MLF1IP	MLF1 interacting protein	0.010
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.010
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.010
LIMK1	LIM domain kinase 1	0.010
PRKCE	protein kinase C, epsilon	0.010
USF1	upstream transcription factor 1	0.010
HMGB3	high mobility group box 3	0.010
TADA2A	transcriptional adaptor 2A	0.010