IMP

Process View

Homo sapiens

22 genes annotated in human

Multi-species View

spermatogenesis

GO:0007283

The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "spermatogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "spermatogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.891
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.379
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.244
ATXN1	ataxin 1	0.224
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.132	Fly
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.121
BRCA2	breast cancer 2, early onset	0.113	Mouse
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.111
CDK2	cyclin-dependent kinase 2	0.091
XIAP	X-linked inhibitor of apoptosis	0.088
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.082
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.070
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.067	Fly
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.066
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.062	Fly
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.059
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.055
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.052
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.052
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	0.049
RIPK2	receptor-interacting serine-threonine kinase 2	0.047
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.042
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.041
SCHIP1	schwannomin interacting protein 1	0.041
WASL	Wiskott-Aldrich syndrome-like	0.039	Fly
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.039	Worm
CCNA2	cyclin A2	0.039
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.039	Fly
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.038
TCP1	t-complex 1	0.037
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.037	Fly
SKP2	S-phase kinase-associated protein 2 (p45)	0.034
NCL	nucleolin	0.034
EXOC7	exocyst complex component 7	0.032
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.031
SYNE1	spectrin repeat containing, nuclear envelope 1	0.031
BCL2	B-cell CLL/lymphoma 2	0.030
NOTCH1	notch 1	0.029	Rat
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.029
SFN	stratifin	0.028
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.028
CDT1	chromatin licensing and DNA replication factor 1	0.028
PLK1	polo-like kinase 1	0.028	Fly
BRCA1	breast cancer 1, early onset	0.027
SRSF2	serine/arginine-rich splicing factor 2	0.027
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.027
NOTCH3	notch 3	0.026
CCNB1	cyclin B1	0.026	Rat
VDAC1	voltage-dependent anion channel 1	0.025	Fly
HSPA8	heat shock 70kDa protein 8	0.025
PHC2	polyhomeotic homolog 2 (Drosophila)	0.025	Mouse
EIF4A2	eukaryotic translation initiation factor 4A2	0.025
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.024
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.024
TARDBP	TAR DNA binding protein	0.024
RORA	RAR-related orphan receptor A	0.023
EIF3L	eukaryotic translation initiation factor 3, subunit L	0.023
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.022
KIF23	kinesin family member 23	0.022
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.022
HMGA1	high mobility group AT-hook 1	0.022	Mouse
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.021	Fly
RBMX	RNA binding motif protein, X-linked	0.021
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.021
SKP1	S-phase kinase-associated protein 1	0.021
CDK1	cyclin-dependent kinase 1	0.021	Fly
ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.021
PTGES3	prostaglandin E synthase 3 (cytosolic)	0.020
CSNK2B	casein kinase 2, beta polypeptide	0.020
LAT	linker for activation of T cells	0.020
BCL2L1	BCL2-like 1	0.020	Mouse
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.020
SOS1	son of sevenless homolog 1 (Drosophila)	0.020
UBC	ubiquitin C	0.020	Fly
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.020
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.019
BAD	BCL2-associated agonist of cell death	0.019
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.019
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.019
PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.019
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.019
GSK3B	glycogen synthase kinase 3 beta	0.019
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.019
CLCN3	chloride channel 3	0.019
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.018
MPDZ	multiple PDZ domain protein	0.018
PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	0.018
HDAC2	histone deacetylase 2	0.017
PML	promyelocytic leukemia	0.017
H3F3B	H3 histone, family 3B (H3.3B)	0.017
FRA10AC1	fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1	0.017
SNX9	sorting nexin 9	0.017
PEX5	peroxisomal biogenesis factor 5	0.017
TSKS	testis-specific serine kinase substrate	0.017
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.017
ARID4B	AT rich interactive domain 4B (RBP1-like)	0.017	Mouse
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.017
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.017	Fly
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.016
XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3	0.016
PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	0.016
VCP	valosin containing protein	0.016
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.016
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.016
MYCBP	c-myc binding protein	0.015
RBBP4	retinoblastoma binding protein 4	0.015
TOB1	transducer of ERBB2, 1	0.015
UQCRC2	ubiquinol-cytochrome c reductase core protein II	0.015
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.015	Fly
EIF3H	eukaryotic translation initiation factor 3, subunit H	0.015
ATF2	activating transcription factor 2	0.015
SMAD3	SMAD family member 3	0.015
TRIM28	tripartite motif containing 28	0.015
RPA1	replication protein A1, 70kDa	0.015
ADNP	activity-dependent neuroprotector homeobox	0.015
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.015
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.014
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.014
WEE1	WEE1 homolog (S. pombe)	0.014
JAG1	jagged 1	0.014	Human
FUBP1	far upstream element (FUSE) binding protein 1	0.014	Fly
IQGAP1	IQ motif containing GTPase activating protein 1	0.013
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.013
CDKN3	cyclin-dependent kinase inhibitor 3	0.013
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.013
AIMP2	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	0.013
PBK	PDZ binding kinase	0.013
EIF3K	eukaryotic translation initiation factor 3, subunit K	0.013
ELL2	elongation factor, RNA polymerase II, 2	0.013
BCR	breakpoint cluster region	0.013
HDAC1	histone deacetylase 1	0.013
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	0.013	Fly
PLEC	plectin	0.013
BBS2	Bardet-Biedl syndrome 2	0.013
PDIA3	protein disulfide isomerase family A, member 3	0.013
BAK1	BCL2-antagonist/killer 1	0.013
CCNE1	cyclin E1	0.012
PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	0.012
FASLG	Fas ligand (TNF superfamily, member 6)	0.012
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.012
GRB10	growth factor receptor-bound protein 10	0.012
EIF3F	eukaryotic translation initiation factor 3, subunit F	0.012
IRS1	insulin receptor substrate 1	0.012	Fly
FANCD2	Fanconi anemia, complementation group D2	0.012
UQCRFS1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.012
CNOT6	CCR4-NOT transcription complex, subunit 6	0.012
DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.012	Mouse
MED28	mediator complex subunit 28	0.012
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.012
BIRC2	baculoviral IAP repeat containing 2	0.012
SET	SET nuclear oncogene	0.012
PABPC1	poly(A) binding protein, cytoplasmic 1	0.012
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.012
UBXN7	UBX domain protein 7	0.012
GAB1	GRB2-associated binding protein 1	0.012
PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	0.012
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.012
CCNB2	cyclin B2	0.012
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.012
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.012
DNM2	dynamin 2	0.011	Fly
ORC1	origin recognition complex, subunit 1	0.011
IGF1R	insulin-like growth factor 1 receptor	0.011	Fly
ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	0.011
COX17	COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)	0.011
DICER1	dicer 1, ribonuclease type III	0.011
CNOT7	CCR4-NOT transcription complex, subunit 7	0.011
CCND1	cyclin D1	0.011
RSBN1	round spermatid basic protein 1	0.011
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.011
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.011
EPS15	epidermal growth factor receptor pathway substrate 15	0.011
CNOT8	CCR4-NOT transcription complex, subunit 8	0.011
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.011	Fly
SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3	0.011
TRIP6	thyroid hormone receptor interactor 6	0.011
USP42	ubiquitin specific peptidase 42	0.011
TLK1	tousled-like kinase 1	0.011
HSPA4	heat shock 70kDa protein 4	0.011
BCOR	BCL6 corepressor	0.011
ARID4A	AT rich interactive domain 4A (RBP1-like)	0.011	Mouse
HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	0.011
STRN3	striatin, calmodulin binding protein 3	0.011
MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.011
DNM1	dynamin 1	0.011	Fly
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.011
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.011
NCOR2	nuclear receptor corepressor 2	0.010
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.010
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.010
PAPOLA	poly(A) polymerase alpha	0.010
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.010
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.010
SYNE2	spectrin repeat containing, nuclear envelope 2	0.010
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.010
PABPN1	poly(A) binding protein, nuclear 1	0.010
HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	0.010
EP300	E1A binding protein p300	0.010	Worm
SP1	Sp1 transcription factor	0.010
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.010
TP53	tumor protein p53	0.010	Zebrafish
NLRC4	NLR family, CARD domain containing 4	0.010