IMP
Process View
negative regulation of mitotic sister chromatid separation
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of mitotic sister chromatid separation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.997 | Fly | |
| CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.991 | ||
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.929 | Yeast | |
| ANAPC4 | anaphase promoting complex subunit 4 | 0.893 | ||
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.613 | ||
| BUB1 | budding uninhibited by benzimidazoles 1 homolog (yeast) | 0.556 | Fly | |
| CDK2 | cyclin-dependent kinase 2 | 0.523 | ||
| ANAPC7 | anaphase promoting complex subunit 7 | 0.430 | ||
| CCNA2 | cyclin A2 | 0.407 | ||
| CCNB1 | cyclin B1 | 0.364 | ||
| BUB3 | budding uninhibited by benzimidazoles 3 homolog (yeast) | 0.352 | Worm Fly | |
| ANAPC5 | anaphase promoting complex subunit 5 | 0.244 | ||
| ANAPC1 | anaphase promoting complex subunit 1 | 0.192 | ||
| CDC16 | cell division cycle 16 homolog (S. cerevisiae) | 0.160 | ||
| DSN1 | DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.148 | ||
| ANAPC11 | anaphase promoting complex subunit 11 | 0.124 | ||
| BRCA2 | breast cancer 2, early onset | 0.100 | ||
| CDC23 | cell division cycle 23 homolog (S. cerevisiae) | 0.081 | ||
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.076 | ||
| CBX5 | chromobox homolog 5 | 0.069 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.066 | ||
| ZWINT | ZW10 interactor | 0.065 | ||
| CASC5 | cancer susceptibility candidate 5 | 0.059 | ||
| CHAF1A | chromatin assembly factor 1, subunit A (p150) | 0.054 | ||
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.050 | ||
| CDC6 | cell division cycle 6 homolog (S. cerevisiae) | 0.048 | ||
| OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.046 | ||
| NDC80 | NDC80 homolog, kinetochore complex component (S. cerevisiae) | 0.045 | ||
| RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.041 | ||
| MYST1 | MYST histone acetyltransferase 1 | 0.039 | ||
| SKA3 | spindle and kinetochore associated complex subunit 3 | 0.039 | ||
| SKA1 | spindle and kinetochore associated complex subunit 1 | 0.038 | ||
| PTTG1 | pituitary tumor-transforming 1 | 0.037 | ||
| CENPE | centromere protein E, 312kDa | 0.036 | Mouse | |
| SKA2 | spindle and kinetochore associated complex subunit 2 | 0.034 | ||
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.034 | ||
| AURKB | aurora kinase B | 0.033 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.033 | ||
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 0.031 | ||
| CDC26 | cell division cycle 26 homolog (S. cerevisiae) | 0.030 | ||
| DOT1L | DOT1-like, histone H3 methyltransferase (S. cerevisiae) | 0.030 | ||
| NUF2 | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.029 | ||
| ORC2 | origin recognition complex, subunit 2 | 0.026 | ||
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 | 0.025 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.024 | ||
| ZNF207 | zinc finger protein 207 | 0.024 | ||
| PRNP | prion protein | 0.023 | ||
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.023 | ||
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.022 | ||
| UHRF1 | ubiquitin-like with PHD and ring finger domains 1 | 0.022 | ||
| FBXO5 | F-box protein 5 | 0.022 | ||
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.021 | ||
| CCDC99 | coiled-coil domain containing 99 | 0.020 | ||
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.020 | ||
| CCNE1 | cyclin E1 | 0.020 | Fly | |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.020 | ||
| CCNB2 | cyclin B2 | 0.019 | ||
| C19orf39 | chromosome 19 open reading frame 39 | 0.019 | ||
| HERC2 | hect domain and RLD 2 | 0.019 | ||
| NEK2 | NIMA (never in mitosis gene a)-related kinase 2 | 0.018 | ||
| SMC3 | structural maintenance of chromosomes 3 | 0.018 | ||
| FXR2 | fragile X mental retardation, autosomal homolog 2 | 0.018 | ||
| H2AFX | H2A histone family, member X | 0.018 | ||
| KIF18A | kinesin family member 18A | 0.018 | ||
| TCP1 | t-complex 1 | 0.018 | ||
| PTEN | phosphatase and tensin homolog | 0.017 | ||
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.017 | ||
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.017 | ||
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.016 | ||
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.016 | ||
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.016 | ||
| HIST1H4A | histone cluster 1, H4a | 0.016 | ||
| SMC4 | structural maintenance of chromosomes 4 | 0.015 | ||
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.015 | ||
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.015 | ||
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | 0.015 | ||
| ATMIN | ATM interactor | 0.015 | ||
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.015 | ||
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 | 0.015 | ||
| RAD52 | RAD52 homolog (S. cerevisiae) | 0.015 | ||
| PPME1 | protein phosphatase methylesterase 1 | 0.015 | ||
| FANCD2 | Fanconi anemia, complementation group D2 | 0.014 | ||
| PARP3 | poly (ADP-ribose) polymerase family, member 3 | 0.014 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.013 | ||
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.013 | ||
| HIST1H1E | histone cluster 1, H1e | 0.013 | ||
| SLX4 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) | 0.012 | ||
| USP44 | ubiquitin specific peptidase 44 | 0.012 | ||
| C13orf34 | chromosome 13 open reading frame 34 | 0.012 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.012 | ||
| BRCA1 | breast cancer 1, early onset | 0.011 | ||
| TTK | TTK protein kinase | 0.011 | Yeast | |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) | 0.011 | ||
| CBX1 | chromobox homolog 1 | 0.011 | ||
| MAD2L1BP | MAD2L1 binding protein | 0.011 | ||
| ANKRD52 | ankyrin repeat domain 52 | 0.011 | ||
| RAD51AP1 | RAD51 associated protein 1 | 0.011 | ||
| USP49 | ubiquitin specific peptidase 49 | 0.011 | Human | |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.011 | ||
| CCNE2 | cyclin E2 | 0.010 | Fly | |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.010 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.010 | ||
| PLK4 | polo-like kinase 4 | 0.010 |