IMP

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Homo sapiens

3 genes annotated in human

respiratory gaseous exchange

The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "respiratory gaseous exchange"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "respiratory gaseous exchange" (in gray)

Name	Description	Probability	Func Analog Organism
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.333
TNNI1	troponin I type 1 (skeletal, slow)	0.318
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.161
ZFX	zinc finger protein, X-linked	0.155
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.123
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.103
MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	0.102
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.100
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.100
ZNF512B	zinc finger protein 512B	0.086
TCEAL5	transcription elongation factor A (SII)-like 5	0.067
GFI1B	growth factor independent 1B transcription repressor	0.065
ARRDC3	arrestin domain containing 3	0.065
ARL4D	ADP-ribosylation factor-like 4D	0.060
POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)	0.058
HIPK2	homeodomain interacting protein kinase 2	0.055
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.044
USP9X	ubiquitin specific peptidase 9, X-linked	0.042
SMAD9	SMAD family member 9	0.039
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.039
JUN	jun proto-oncogene	0.038
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.035
ATN1	atrophin 1	0.035
BCL6	B-cell CLL/lymphoma 6	0.035
RGS2	regulator of G-protein signaling 2, 24kDa	0.033
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.033
ADORA2A	adenosine A2a receptor	0.032
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.030
GRIN3B	glutamate receptor, ionotropic, N-methyl-D-aspartate 3B	0.028
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.026
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.025
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.025
PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.025
ING2	inhibitor of growth family, member 2	0.025
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.024
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.024
HOXA4	homeobox A4	0.024
CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.023
HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2	0.023
HOXA10	homeobox A10	0.022
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.022
TNNI2	troponin I type 2 (skeletal, fast)	0.022
RBBP5	retinoblastoma binding protein 5	0.022
HOXA7	homeobox A7	0.022
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.021
MAST1	microtubule associated serine/threonine kinase 1	0.021
TNNT2	troponin T type 2 (cardiac)	0.021
NCF1	neutrophil cytosolic factor 1	0.021
EGR3	early growth response 3	0.020
EGR2	early growth response 2	0.020
MAP2K7	mitogen-activated protein kinase kinase 7	0.020
CCNL1	cyclin L1	0.020
RIC8A	resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)	0.019
SMAD1	SMAD family member 1	0.019
NELL2	NEL-like 2 (chicken)	0.019
CRYZ	crystallin, zeta (quinone reductase)	0.019
PDZD4	PDZ domain containing 4	0.018
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.018
DRD2	dopamine receptor D2	0.018
PRKCB	protein kinase C, beta	0.018
NFIL3	nuclear factor, interleukin 3 regulated	0.017
MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	0.017
ACAP3	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	0.017
KLF4	Kruppel-like factor 4 (gut)	0.017
TRIP6	thyroid hormone receptor interactor 6	0.017
ATF2	activating transcription factor 2	0.017
CYR61	cysteine-rich, angiogenic inducer, 61	0.016
MON1A	MON1 homolog A (yeast)	0.016
HDAC4	histone deacetylase 4	0.016
HAND2	heart and neural crest derivatives expressed 2	0.016
NOTCH3	notch 3	0.016
TIPARP	TCDD-inducible poly(ADP-ribose) polymerase	0.016
NBR1	neighbor of BRCA1 gene 1	0.016
RAD23B	RAD23 homolog B (S. cerevisiae)	0.016
TNNI3	troponin I type 3 (cardiac)	0.016
MLL2	myeloid/lymphoid or mixed-lineage leukemia 2	0.016
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.015
GADD45B	growth arrest and DNA-damage-inducible, beta	0.015
JUNB	jun B proto-oncogene	0.015
EGFL7	EGF-like-domain, multiple 7	0.015
BEGAIN	brain-enriched guanylate kinase-associated homolog (rat)	0.015
KLF9	Kruppel-like factor 9	0.015
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.015
COL20A1	collagen, type XX, alpha 1	0.015
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.015
PHACTR3	phosphatase and actin regulator 3	0.015
MEIS1	Meis homeobox 1	0.015
DTX3	deltex homolog 3 (Drosophila)	0.015
PSAP	prosaposin	0.015
SEPT11	septin 11	0.014
KLF5	Kruppel-like factor 5 (intestinal)	0.014
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.014
PELI1	pellino homolog 1 (Drosophila)	0.014
MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.014
SGK1	serum/glucocorticoid regulated kinase 1	0.014
SGSH	N-sulfoglucosamine sulfohydrolase	0.014
KLF10	Kruppel-like factor 10	0.014
TRIM9	tripartite motif containing 9	0.014
TMEM59L	transmembrane protein 59-like	0.014
EGR1	early growth response 1	0.014
FOXD3	forkhead box D3	0.014
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.014
PRKCA	protein kinase C, alpha	0.014
CPEB4	cytoplasmic polyadenylation element binding protein 4	0.014
HOXB5	homeobox B5	0.014
TOB1	transducer of ERBB2, 1	0.014
MAN2B1	mannosidase, alpha, class 2B, member 1	0.014
ESD	esterase D	0.013
C9orf25	chromosome 9 open reading frame 25	0.013
KLF6	Kruppel-like factor 6	0.013
RUNX1	runt-related transcription factor 1	0.013
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.013
NRXN1	neurexin 1	0.013
BCOR	BCL6 corepressor	0.013
IER2	immediate early response 2	0.013
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.013
CACNB1	calcium channel, voltage-dependent, beta 1 subunit	0.013
ARL4C	ADP-ribosylation factor-like 4C	0.013
NCOA6	nuclear receptor coactivator 6	0.013
SLC38A2	solute carrier family 38, member 2	0.013
NXPH3	neurexophilin 3	0.013
SIN3B	SIN3 homolog B, transcription regulator (yeast)	0.013
USHBP1	Usher syndrome 1C binding protein 1	0.013
TBC1D10A	TBC1 domain family, member 10A	0.013
VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	0.013
FBXO33	F-box protein 33	0.013
IL6R	interleukin 6 receptor	0.013
EFNA3	ephrin-A3	0.013
DLG4	discs, large homolog 4 (Drosophila)	0.013
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.013
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.013
NUMBL	numb homolog (Drosophila)-like	0.013
BTG2	BTG family, member 2	0.013
SIK1	salt-inducible kinase 1	0.013
ACHE	acetylcholinesterase	0.013
MAP3K10	mitogen-activated protein kinase kinase kinase 10	0.013
ECI2	enoyl-CoA delta isomerase 2	0.013
IFRD1	interferon-related developmental regulator 1	0.013
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.013
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.013
GIGYF1	GRB10 interacting GYF protein 1	0.013
EIF1	eukaryotic translation initiation factor 1	0.013
LTBP4	latent transforming growth factor beta binding protein 4	0.012
NOTCH1	notch 1	0.012
PMF1	polyamine-modulated factor 1	0.012
HOXA6	homeobox A6	0.012
ZBTB4	zinc finger and BTB domain containing 4	0.012
BDH2	3-hydroxybutyrate dehydrogenase, type 2	0.012
PTPRN	protein tyrosine phosphatase, receptor type, N	0.012
POU4F3	POU class 4 homeobox 3	0.012
PTGER1	prostaglandin E receptor 1 (subtype EP1), 42kDa	0.012
CACNG2	calcium channel, voltage-dependent, gamma subunit 2	0.012
DLG2	discs, large homolog 2 (Drosophila)	0.012
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.012
ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	0.012
BAI1	brain-specific angiogenesis inhibitor 1	0.012
DLL4	delta-like 4 (Drosophila)	0.012
TNNT1	troponin T type 1 (skeletal, slow)	0.012
PRKCG	protein kinase C, gamma	0.012
FBXL15	F-box and leucine-rich repeat protein 15	0.012
PLEKHO1	pleckstrin homology domain containing, family O member 1	0.012
SLIT1	slit homolog 1 (Drosophila)	0.012
ARHGAP33	Rho GTPase activating protein 33	0.012
SRCIN1	SRC kinase signaling inhibitor 1	0.012
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.012
HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	0.012
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.012
CHRD	chordin	0.012
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.012
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.012
NAMPT	nicotinamide phosphoribosyltransferase	0.012
NUP210	nucleoporin 210kDa	0.012
HOXA2	homeobox A2	0.012
USP15	ubiquitin specific peptidase 15	0.012
GRN	granulin	0.012
SMAD3	SMAD family member 3	0.012
NRXN3	neurexin 3	0.012
CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	0.012
RUNDC3A	RUN domain containing 3A	0.012
TNK2	tyrosine kinase, non-receptor, 2	0.011
RPH3A	rabphilin 3A homolog (mouse)	0.011
FNDC3A	fibronectin type III domain containing 3A	0.011
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.011
RIMS1	regulating synaptic membrane exocytosis 1	0.011
CDX2	caudal type homeobox 2	0.011
NLGN2	neuroligin 2	0.011	Mouse
SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	0.011
LBX1	ladybird homeobox 1	0.011
MEGF11	multiple EGF-like-domains 11	0.011
PYY	peptide YY	0.011
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.011
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.011
PHF12	PHD finger protein 12	0.011
PDX1	pancreatic and duodenal homeobox 1	0.011
BRF1	BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)	0.011
NECAB2	N-terminal EF-hand calcium binding protein 2	0.011
PDE4D	phosphodiesterase 4D, cAMP-specific	0.011
MPP2	membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)	0.011
MARK4	MAP/microtubule affinity-regulating kinase 4	0.011
FTL	ferritin, light polypeptide	0.011
DMPK	dystrophia myotonica-protein kinase	0.011
KCNE3	potassium voltage-gated channel, Isk-related family, member 3	0.011
CALCRL	calcitonin receptor-like	0.011
NRXN2	neurexin 2	0.011
NTM	neurotrimin	0.011
BHLHE23	basic helix-loop-helix family, member e23	0.011
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.011
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.011
WDR26	WD repeat domain 26	0.011
CHST8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.011
SPATA20	spermatogenesis associated 20	0.011
MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	0.011
BTG1	B-cell translocation gene 1, anti-proliferative	0.011
SIX4	SIX homeobox 4	0.011
TMEM14A	transmembrane protein 14A	0.011
URB1	URB1 ribosome biogenesis 1 homolog (S. cerevisiae)	0.011
KDM3B	lysine (K)-specific demethylase 3B	0.011
BMP2	bone morphogenetic protein 2	0.011
PHKB	phosphorylase kinase, beta	0.011
SLC32A1	solute carrier family 32 (GABA vesicular transporter), member 1	0.011
TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	0.011
SETD1A	SET domain containing 1A	0.011
NPPC	natriuretic peptide C	0.011
LCOR	ligand dependent nuclear receptor corepressor	0.011
ADAM15	ADAM metallopeptidase domain 15	0.011
ANKS3	ankyrin repeat and sterile alpha motif domain containing 3	0.011
HOXA1	homeobox A1	0.011
TIMP2	TIMP metallopeptidase inhibitor 2	0.011
KBTBD2	kelch repeat and BTB (POZ) domain containing 2	0.011
PTPRA	protein tyrosine phosphatase, receptor type, A	0.011
CREM	cAMP responsive element modulator	0.010
CKB	creatine kinase, brain	0.010
ACTL6B	actin-like 6B	0.010
KDM6B	lysine (K)-specific demethylase 6B	0.010
KIAA0284	KIAA0284	0.010
CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2	0.010
DUSP4	dual specificity phosphatase 4	0.010
PALM	paralemmin	0.010
MEGF6	multiple EGF-like-domains 6	0.010
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.010
DUSP1	dual specificity phosphatase 1	0.010
SNCG	synuclein, gamma (breast cancer-specific protein 1)	0.010
FOXB1	forkhead box B1	0.010
REEP2	receptor accessory protein 2	0.010
CYB5A	cytochrome b5 type A (microsomal)	0.010
SNX13	sorting nexin 13	0.010
ALDH7A1	aldehyde dehydrogenase 7 family, member A1	0.010
FBRS	fibrosin	0.010
CBX7	chromobox homolog 7	0.010
CAMK2B	calcium/calmodulin-dependent protein kinase II beta	0.010
SPTBN4	spectrin, beta, non-erythrocytic 4	0.010
HES7	hairy and enhancer of split 7 (Drosophila)	0.010
MAPK4	mitogen-activated protein kinase 4	0.010
PGRMC2	progesterone receptor membrane component 2	0.010
NPAS1	neuronal PAS domain protein 1	0.010
ARID5B	AT rich interactive domain 5B (MRF1-like)	0.010
IQSEC1	IQ motif and Sec7 domain 1	0.010
OPRD1	opioid receptor, delta 1	0.010
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.010
CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.010
FANCG	Fanconi anemia, complementation group G	0.010
LPPR2	lipid phosphate phosphatase-related protein type 2	0.010
C20orf201	chromosome 20 open reading frame 201	0.010
ZBED5	zinc finger, BED-type containing 5	0.010
CASP6	caspase 6, apoptosis-related cysteine peptidase	0.010
GPRC5B	G protein-coupled receptor, family C, group 5, member B	0.010
VGLL3	vestigial like 3 (Drosophila)	0.010
CHD8	chromodomain helicase DNA binding protein 8	0.010
SPTBN2	spectrin, beta, non-erythrocytic 2	0.010
SEMA6C	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C	0.010
PDCD6IP	programmed cell death 6 interacting protein	0.010
TRPS1	trichorhinophalangeal syndrome I	0.010