IMP

Process View

Homo sapiens

4 genes annotated in human

Multi-species View

regulation of interleukin 10 secretion

GO:2001179

Any process that modulates the frequency, rate or extent of interleukin-10 secretion.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interleukin 10 secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of interleukin 10 secretion" (in gray)

Name	Description	Probability	Func Analog Organism
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.994
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.992
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.987
BTN3A3	butyrophilin, subfamily 3, member A3	0.983	Human
HLA-DMB	major histocompatibility complex, class II, DM beta	0.951
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.940	Human
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.921
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.876
HLA-G	major histocompatibility complex, class I, G	0.851
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.846	Human
BTN3A2	butyrophilin, subfamily 3, member A2	0.786	Human
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.773
PILRA	paired immunoglobin-like type 2 receptor alpha	0.750
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.730
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.727
BTN3A1	butyrophilin, subfamily 3, member A1	0.507	Human
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.465	Human
SIGLEC7	sialic acid binding Ig-like lectin 7	0.437
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.383
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.364
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.358	Human
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.352	Human
CD80	CD80 molecule	0.340
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.336
NLRC4	NLR family, CARD domain containing 4	0.232
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.164
MEFV	Mediterranean fever	0.154
HCP5	HLA complex P5	0.147
PTAFR	platelet-activating factor receptor	0.111
NLRP3	NLR family, pyrin domain containing 3	0.110
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.108
BTN2A2	butyrophilin, subfamily 2, member A2	0.088	Human
HK3	hexokinase 3 (white cell)	0.082
TRAF1	TNF receptor-associated factor 1	0.077
TREM1	triggering receptor expressed on myeloid cells 1	0.071
CCR1	chemokine (C-C motif) receptor 1	0.069
SNAP23	synaptosomal-associated protein, 23kDa	0.062
HLA-F	major histocompatibility complex, class I, F	0.058
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.045
AOAH	acyloxyacyl hydrolase (neutrophil)	0.043
CSK	c-src tyrosine kinase	0.041
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.040
NUMB	numb homolog (Drosophila)	0.037
NLRC5	NLR family, CARD domain containing 5	0.037
UBA7	ubiquitin-like modifier activating enzyme 7	0.036
CD86	CD86 molecule	0.032	Human
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.032
CCDC115	coiled-coil domain containing 115	0.031
SIRPB1	signal-regulatory protein beta 1	0.031
HLA-DQA2	major histocompatibility complex, class II, DQ alpha 2	0.031
CD33	CD33 molecule	0.031
CD40	CD40 molecule, TNF receptor superfamily member 5	0.031
ZNF71	zinc finger protein 71	0.030
SIGLEC9	sialic acid binding Ig-like lectin 9	0.029
CD300C	CD300c molecule	0.028
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.027
NOD2	nucleotide-binding oligomerization domain containing 2	0.027
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.025	Human
RARRES3	retinoic acid receptor responder (tazarotene induced) 3	0.025
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.025
BST2	bone marrow stromal cell antigen 2	0.024
DOCK7	dedicator of cytokinesis 7	0.024
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.023
SLC15A3	solute carrier family 15, member 3	0.023
RASSF4	Ras association (RalGDS/AF-6) domain family member 4	0.023
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.022	Human
CCL4	chemokine (C-C motif) ligand 4	0.021
TFF1	trefoil factor 1	0.021
RFX5	regulatory factor X, 5 (influences HLA class II expression)	0.021
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.020
PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	0.020
NMT2	N-myristoyltransferase 2	0.020
APOL3	apolipoprotein L, 3	0.019
TLR8	toll-like receptor 8	0.019
CD72	CD72 molecule	0.019
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.019
LGALS9	lectin, galactoside-binding, soluble, 9	0.019
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.018	Human
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.018
IRF8	interferon regulatory factor 8	0.018
FCAR	Fc fragment of IgA, receptor for	0.018	Human
APOL1	apolipoprotein L, 1	0.018
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.017
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.017
EXT2	exostosin 2	0.017
BTN2A1	butyrophilin, subfamily 2, member A1	0.017	Human
CYTH4	cytohesin 4	0.017
FPR2	formyl peptide receptor 2	0.017
MARCH1	membrane-associated ring finger (C3HC4) 1	0.017
VHL	von Hippel-Lindau tumor suppressor	0.017
PHF11	PHD finger protein 11	0.017
CD1D	CD1d molecule	0.016
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.016
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.016
AIM2	absent in melanoma 2	0.016
RIPK2	receptor-interacting serine-threonine kinase 2	0.016
SIGLEC5	sialic acid binding Ig-like lectin 5	0.016
ERAP2	endoplasmic reticulum aminopeptidase 2	0.015
AIF1	allograft inflammatory factor 1	0.015
ADPRH	ADP-ribosylarginine hydrolase	0.015
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.015
CD22	CD22 molecule	0.015
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.014
CECR1	cat eye syndrome chromosome region, candidate 1	0.014
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.014
EMR3	egf-like module containing, mucin-like, hormone receptor-like 3	0.014
BEST1	bestrophin 1	0.014
SIRPA	signal-regulatory protein alpha	0.014
EPOR	erythropoietin receptor	0.014
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.014
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	0.014
SLAMF8	SLAM family member 8	0.014
HLA-B	major histocompatibility complex, class I, B	0.014
DPEP2	dipeptidase 2	0.014
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.014
TYMP	thymidine phosphorylase	0.014
PECAM1	platelet/endothelial cell adhesion molecule	0.014
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.014
GPR132	G protein-coupled receptor 132	0.014
PYDC2	pyrin domain containing 2	0.013
TXNDC3	thioredoxin domain containing 3 (spermatozoa)	0.013
TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	0.013
CD300A	CD300a molecule	0.013
SLAMF7	SLAM family member 7	0.013
FOLR3	folate receptor 3 (gamma)	0.013
APOBEC3C	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C	0.013
TAPBPL	TAP binding protein-like	0.013
BIN2	bridging integrator 2	0.013
P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7	0.013
ASGR2	asialoglycoprotein receptor 2	0.013
VSIG4	V-set and immunoglobulin domain containing 4	0.013
ROS1	c-ros oncogene 1 , receptor tyrosine kinase	0.013
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.012
FGB	fibrinogen beta chain	0.012
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.012
GBP4	guanylate binding protein 4	0.012
POU2F2	POU class 2 homeobox 2	0.012
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.012
IL15	interleukin 15	0.012
TRIM6-TRIM34	TRIM6-TRIM34 readthrough	0.012
PLXNA1	plexin A1	0.012
HLA-DQB2	major histocompatibility complex, class II, DQ beta 2	0.012
BCL2A1	BCL2-related protein A1	0.011
APP	amyloid beta (A4) precursor protein	0.011
CCL22	chemokine (C-C motif) ligand 22	0.011
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.011
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.011
KIR2DL3	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3	0.011
KIR2DL1	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1	0.011
RAB7L1	RAB7, member RAS oncogene family-like 1	0.011
CMKLR1	chemokine-like receptor 1	0.011
IRF5	interferon regulatory factor 5	0.011
BPI	bactericidal/permeability-increasing protein	0.011
GIMAP2	GTPase, IMAP family member 2	0.011
LY86	lymphocyte antigen 86	0.011
AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	0.011
APOBR	apolipoprotein B receptor	0.011
C17orf60	chromosome 17 open reading frame 60	0.011
MARCO	macrophage receptor with collagenous structure	0.011
APLP1	amyloid beta (A4) precursor-like protein 1	0.010
BAX	BCL2-associated X protein	0.010
LGALS2	lectin, galactoside-binding, soluble, 2	0.010
EBI3	Epstein-Barr virus induced 3	0.010
CCL24	chemokine (C-C motif) ligand 24	0.010
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.010
ETV7	ets variant 7	0.010
SETD7	SET domain containing (lysine methyltransferase) 7	0.010