IMP
Process View
positive regulation of superoxide anion generation
Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of superoxide anion generation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| IL8 | interleukin 8 | 0.947 | ||
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.847 | Mouse | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.828 | Mouse | |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.705 | Mouse | |
| PRDX1 | peroxiredoxin 1 | 0.598 | ||
| IL1B | interleukin 1, beta | 0.446 | ||
| NOXA1 | NADPH oxidase activator 1 | 0.356 | ||
| PRKCZ | protein kinase C, zeta | 0.344 | Human | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.313 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.287 | ||
| NCF1 | neutrophil cytosolic factor 1 | 0.284 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.239 | ||
| ENG | endoglin | 0.173 | ||
| PARD6A | par-6 partitioning defective 6 homolog alpha (C. elegans) | 0.149 | ||
| CCL20 | chemokine (C-C motif) ligand 20 | 0.146 | ||
| IL6 | interleukin 6 (interferon, beta 2) | 0.144 | ||
| NUMB | numb homolog (Drosophila) | 0.143 | ||
| PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.137 | ||
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.119 | ||
| ZNF71 | zinc finger protein 71 | 0.115 | ||
| CDCP1 | CUB domain containing protein 1 | 0.110 | ||
| DCTN1 | dynactin 1 | 0.087 | ||
| CCDC115 | coiled-coil domain containing 115 | 0.086 | ||
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.085 | ||
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.074 | ||
| CARD11 | caspase recruitment domain family, member 11 | 0.071 | ||
| PARD3 | par-3 partitioning defective 3 homolog (C. elegans) | 0.066 | ||
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.059 | ||
| IER3 | immediate early response 3 | 0.056 | ||
| RARA | retinoic acid receptor, alpha | 0.053 | ||
| PRKCB | protein kinase C, beta | 0.052 | ||
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.051 | ||
| PPP2R4 | protein phosphatase 2A activator, regulatory subunit 4 | 0.050 | ||
| PICK1 | protein interacting with PRKCA 1 | 0.047 | ||
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.046 | ||
| SH3RF1 | SH3 domain containing ring finger 1 | 0.046 | ||
| MAPT | microtubule-associated protein tau | 0.044 | ||
| CYBA | cytochrome b-245, alpha polypeptide | 0.041 | ||
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.040 | ||
| TGFB3 | transforming growth factor, beta 3 | 0.039 | ||
| PARK7 | Parkinson disease (autosomal recessive, early onset) 7 | 0.037 | ||
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.037 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.035 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.034 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.033 | Human | |
| APP | amyloid beta (A4) precursor protein | 0.032 | ||
| NMT2 | N-myristoyltransferase 2 | 0.029 | ||
| ARRB1 | arrestin, beta 1 | 0.028 | ||
| TSC22D1 | TSC22 domain family, member 1 | 0.028 | ||
| THBS1 | thrombospondin 1 | 0.028 | ||
| TRIM9 | tripartite motif containing 9 | 0.027 | ||
| ASXL1 | additional sex combs like 1 (Drosophila) | 0.027 | ||
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.027 | ||
| PLAUR | plasminogen activator, urokinase receptor | 0.026 | ||
| CD2 | CD2 molecule | 0.025 | ||
| BCL10 | B-cell CLL/lymphoma 10 | 0.024 | ||
| LCK | lymphocyte-specific protein tyrosine kinase | 0.024 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.024 | ||
| STK4 | serine/threonine kinase 4 | 0.024 | ||
| INADL | InaD-like (Drosophila) | 0.024 | ||
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.024 | ||
| BAD | BCL2-associated agonist of cell death | 0.024 | ||
| VHL | von Hippel-Lindau tumor suppressor | 0.023 | ||
| CCL14 | chemokine (C-C motif) ligand 14 | 0.023 | ||
| PTEN | phosphatase and tensin homolog | 0.022 | ||
| ACTB | actin, beta | 0.021 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.021 | ||
| MBD1 | methyl-CpG binding domain protein 1 | 0.021 | ||
| SQSTM1 | sequestosome 1 | 0.020 | ||
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.019 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.019 | ||
| GFAP | glial fibrillary acidic protein | 0.019 | ||
| COX6C | cytochrome c oxidase subunit VIc | 0.019 | ||
| SOD2 | superoxide dismutase 2, mitochondrial | 0.019 | ||
| PRKCA | protein kinase C, alpha | 0.018 | ||
| PEBP4 | phosphatidylethanolamine-binding protein 4 | 0.018 | ||
| SMG1 | SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) | 0.018 | ||
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.018 | ||
| CCL2 | chemokine (C-C motif) ligand 2 | 0.018 | ||
| CCHCR1 | coiled-coil alpha-helical rod protein 1 | 0.018 | ||
| LIF | leukemia inhibitory factor (cholinergic differentiation factor) | 0.016 | ||
| PRDX6 | peroxiredoxin 6 | 0.016 | ||
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.016 | ||
| FAM129A | family with sequence similarity 129, member A | 0.016 | ||
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.015 | ||
| PAWR | PRKC, apoptosis, WT1, regulator | 0.015 | ||
| THEM4 | thioesterase superfamily member 4 | 0.015 | ||
| DPP4 | dipeptidyl-peptidase 4 | 0.015 | ||
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.015 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.015 | ||
| SH2D1A | SH2 domain containing 1A | 0.014 | ||
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.014 | ||
| PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.014 | ||
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 0.014 | Human | |
| PPP1R10 | protein phosphatase 1, regulatory (inhibitor) subunit 10 | 0.014 | ||
| INHBA | inhibin, beta A | 0.014 | ||
| FABP4 | fatty acid binding protein 4, adipocyte | 0.014 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.014 | ||
| MAP1LC3A | microtubule-associated protein 1 light chain 3 alpha | 0.014 | ||
| MED25 | mediator complex subunit 25 | 0.014 | ||
| SEPT11 | septin 11 | 0.013 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.013 | ||
| IL32 | interleukin 32 | 0.013 | ||
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit | 0.013 | ||
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.013 | ||
| POFUT1 | protein O-fucosyltransferase 1 | 0.013 | ||
| ACVR2B | activin A receptor, type IIB | 0.013 | ||
| PROCR | protein C receptor, endothelial | 0.013 | ||
| SORBS2 | sorbin and SH3 domain containing 2 | 0.013 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.013 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.013 | ||
| MMP1 | matrix metallopeptidase 1 (interstitial collagenase) | 0.012 | ||
| BAG3 | BCL2-associated athanogene 3 | 0.012 | ||
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.012 | ||
| CD247 | CD247 molecule | 0.012 | ||
| TGFBR3 | transforming growth factor, beta receptor III | 0.012 | ||
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.012 | ||
| SETDB1 | SET domain, bifurcated 1 | 0.012 | ||
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.012 | ||
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.012 | ||
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.012 | ||
| PI3 | peptidase inhibitor 3, skin-derived | 0.011 | ||
| NRP1 | neuropilin 1 | 0.011 | ||
| PNMA1 | paraneoplastic antigen MA1 | 0.011 | ||
| MAFF | v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) | 0.011 | ||
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.011 | ||
| WWC1 | WW and C2 domain containing 1 | 0.011 | ||
| BAG1 | BCL2-associated athanogene | 0.011 | ||
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.011 | ||
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.011 | ||
| SH2D2A | SH2 domain containing 2A | 0.011 | ||
| SAMD4B | sterile alpha motif domain containing 4B | 0.011 | ||
| RGS1 | regulator of G-protein signaling 1 | 0.011 | ||
| ADAP1 | ArfGAP with dual PH domains 1 | 0.011 | ||
| PTX3 | pentraxin 3, long | 0.011 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.011 | ||
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.011 | ||
| MMP10 | matrix metallopeptidase 10 (stromelysin 2) | 0.010 | ||
| SCAMP1 | secretory carrier membrane protein 1 | 0.010 | ||
| ZHX1 | zinc fingers and homeoboxes 1 | 0.010 | ||
| F11R | F11 receptor | 0.010 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.010 | ||
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.010 | ||
| PRKCQ | protein kinase C, theta | 0.010 | Human | |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) | 0.010 | ||
| RASSF3 | Ras association (RalGDS/AF-6) domain family member 3 | 0.010 | ||
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | 0.010 | ||
| PNPLA3 | patatin-like phospholipase domain containing 3 | 0.010 | ||
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.010 | ||
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.010 | ||
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.010 | ||
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.010 | ||
| SELE | selectin E | 0.010 | ||
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.010 | ||
| ITK | IL2-inducible T-cell kinase | 0.010 |