IMP

Process View

Mus musculus

18 genes annotated in mouse

dicarboxylic acid metabolic process

The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dicarboxylic acid metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dicarboxylic acid metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Stat5a	signal transducer and activator of transcription 5A	0.985
Stat5b	signal transducer and activator of transcription 5B	0.903
Lepr	leptin receptor	0.876
Esr1	estrogen receptor 1 (alpha)	0.827
Cs	citrate synthase	0.826
Lep	leptin	0.757
Prlr	prolactin receptor	0.534	Mouse
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	0.441
Ar	androgen receptor	0.438
Aco2	aconitase 2, mitochondrial	0.357
Irf9	interferon regulatory factor 9	0.346
Foxp3	forkhead box P3	0.343
Stat3	signal transducer and activator of transcription 3	0.314	Mouse
Uqcrc2	ubiquinol cytochrome c reductase core protein 2	0.312
Immt	inner membrane protein, mitochondrial	0.259
Ndufv1	NADH dehydrogenase (ubiquinone) flavoprotein 1	0.251
Tgfb1	transforming growth factor, beta 1	0.243
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.215
Ndufs1	NADH dehydrogenase (ubiquinone) Fe-S protein 1	0.211
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.206
Il10	interleukin 10	0.166
Idh3g	isocitrate dehydrogenase 3 (NAD+), gamma	0.149	Rat
Thrb	thyroid hormone receptor beta	0.149
Acsl1	acyl-CoA synthetase long-chain family member 1	0.141
Rxra	retinoid X receptor alpha	0.131
Cav1	caveolin 1, caveolae protein	0.131
Cyc1	cytochrome c-1	0.118
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.107
Smad3	MAD homolog 3 (Drosophila)	0.105
Esr2	estrogen receptor 2 (beta)	0.097
Trp53	transformation related protein 53	0.097
Hsd3b4	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4	0.094
Dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	0.091
Il6st	interleukin 6 signal transducer	0.079
Pnpla2	patatin-like phospholipase domain containing 2	0.078
Sdhd	succinate dehydrogenase complex, subunit D, integral membrane protein	0.076
Acads	acyl-Coenzyme A dehydrogenase, short chain	0.075
Mdh1	malate dehydrogenase 1, NAD (soluble)	0.075
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.069
Tdo2	tryptophan 2,3-dioxygenase	0.067
Kit	kit oncogene	0.067
Trim21	tripartite motif-containing 21	0.066
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.066
Atad3a	ATPase family, AAA domain containing 3A	0.066
Vdac1	voltage-dependent anion channel 1	0.065
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.062
Ndufa10	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10	0.061
Nos1	nitric oxide synthase 1, neuronal	0.053
Ghr	growth hormone receptor	0.053
Ahr	aryl-hydrocarbon receptor	0.052
Drd2	dopamine receptor D2	0.052
Il4ra	interleukin 4 receptor, alpha	0.050
Got1	glutamate oxaloacetate transaminase 1, soluble	0.047
Insr	insulin receptor	0.045
Pparg	peroxisome proliferator activated receptor gamma	0.044	Mouse
Gjb1	gap junction protein, beta 1	0.043
Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta	0.043
Hadh	hydroxyacyl-Coenzyme A dehydrogenase	0.043
Mobp	myelin-associated oligodendrocytic basic protein	0.042
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.041
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.040
Apoe	apolipoprotein E	0.037
Scd1	stearoyl-Coenzyme A desaturase 1	0.036
Pcx	pyruvate carboxylase	0.036	Rat
Trap1	TNF receptor-associated protein 1	0.034
Uqcrfs1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.034
Irs2	insulin receptor substrate 2	0.032
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.032
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.032
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.031
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.031
Ndufs2	NADH dehydrogenase (ubiquinone) Fe-S protein 2	0.031
Pbld1	phenazine biosynthesis-like protein domain containing 1	0.030
Il1r1	interleukin 1 receptor, type I	0.030
Fh1	fumarate hydratase 1	0.030	Yeast
Adra1b	adrenergic receptor, alpha 1b	0.030
Car5a	carbonic anhydrase 5a, mitochondrial	0.030
Stat6	signal transducer and activator of transcription 6	0.030	Mouse
Ndufa9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9	0.029
Acot4	acyl-CoA thioesterase 4	0.029
Mmachc	methylmalonic aciduria cblC type, with homocystinuria	0.028
Jak2	Janus kinase 2	0.028
Csf1	colony stimulating factor 1 (macrophage)	0.026
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.026
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.026
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.026
Hnf4a	hepatic nuclear factor 4, alpha	0.026
Pten	phosphatase and tensin homolog	0.026
Sdsl	serine dehydratase-like	0.026
Fam73b	family with sequence similarity 73, member B	0.025
Hccs	holocytochrome c synthetase	0.025
Rdh16	retinol dehydrogenase 16	0.025
Etfa	electron transferring flavoprotein, alpha polypeptide	0.024
Aldob	aldolase B, fructose-bisphosphate	0.023
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.023
Slc25a4	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4	0.023
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.023
Npy2r	neuropeptide Y receptor Y2	0.022
Mat1a	methionine adenosyltransferase I, alpha	0.022
Cyp4a31	cytochrome P450, family 4, subfamily a, polypeptide 31	0.022
Aldoa	aldolase A, fructose-bisphosphate	0.022
Slc25a5	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5	0.021
Thrsp	thyroid hormone responsive SPOT14 homolog (Rattus)	0.021
Sik3	SIK family kinase 3	0.021
Akap1	A kinase (PRKA) anchor protein 1	0.021
Atp5g3	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)	0.021
H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	0.021
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.021
Nadk	NAD kinase	0.021
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.020
Cyp2c39	cytochrome P450, family 2, subfamily c, polypeptide 39	0.020
Uqcrc1	ubiquinol-cytochrome c reductase core protein 1	0.020
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.020
Echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.020
Ifnar2	interferon (alpha and beta) receptor 2	0.020
Apc	adenomatosis polyposis coli	0.020
Gckr	glucokinase regulatory protein	0.020
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.020
Pomc	pro-opiomelanocortin-alpha	0.020
Upp2	uridine phosphorylase 2	0.019
Slc17a6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6	0.019
Aco1	aconitase 1	0.019
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.019
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.019	Mouse
Coq9	coenzyme Q9 homolog (yeast)	0.019
Wwox	WW domain-containing oxidoreductase	0.019
Btrc	beta-transducin repeat containing protein	0.019
Nfil3	nuclear factor, interleukin 3, regulated	0.018
Shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	0.018
Pgr	progesterone receptor	0.018
Idh3b	isocitrate dehydrogenase 3 (NAD+) beta	0.018	Rat
Apoa4	apolipoprotein A-IV	0.017
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.017
Otx2	orthodenticle homolog 2 (Drosophila)	0.017
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.017
Pdha1	pyruvate dehydrogenase E1 alpha 1	0.017
Ang2	angiogenin, ribonuclease A family, member 2	0.017
Ptgs2	prostaglandin-endoperoxide synthase 2	0.017
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.017
Ndufs7	NADH dehydrogenase (ubiquinone) Fe-S protein 7	0.017
Brp44l	brain protein 44-like	0.016
Slc25a3	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3	0.016
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.016
Slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.016
Syt1	synaptotagmin I	0.016
1300001I01Rik	RIKEN cDNA 1300001I01 gene	0.016
Kcnab3	potassium voltage-gated channel, shaker-related subfamily, beta member 3	0.016
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.016
Adar	adenosine deaminase, RNA-specific	0.016
Npy1r	neuropeptide Y receptor Y1	0.016
Aifm1	apoptosis-inducing factor, mitochondrion-associated 1	0.016
Acot3	acyl-CoA thioesterase 3	0.015	Mouse
Aldh8a1	aldehyde dehydrogenase 8 family, member A1	0.015
Retsat	retinol saturase (all trans retinol 13,14 reductase)	0.015
Cldn2	claudin 2	0.015
Crb3	crumbs homolog 3 (Drosophila)	0.015
Acy1	aminoacylase 1	0.015
Gfm1	G elongation factor, mitochondrial 1	0.015
Khk	ketohexokinase	0.015
Rc3h1	RING CCCH (C3H) domains 1	0.015
Afg3l2	AFG3(ATPase family gene 3)-like 2 (yeast)	0.015
Hgd	homogentisate 1, 2-dioxygenase	0.015
Tlr4	toll-like receptor 4	0.015
Igf1	insulin-like growth factor 1	0.015
Asgr2	asialoglycoprotein receptor 2	0.015
Bckdhb	branched chain ketoacid dehydrogenase E1, beta polypeptide	0.014
Gldc	glycine decarboxylase	0.014
Acat1	acetyl-Coenzyme A acetyltransferase 1	0.014
Aldh1l1	aldehyde dehydrogenase 1 family, member L1	0.014
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.014
Pdhx	pyruvate dehydrogenase complex, component X	0.014
Etfdh	electron transferring flavoprotein, dehydrogenase	0.014
Orm2	orosomucoid 2	0.013
Glud1	glutamate dehydrogenase 1	0.013	Human
Acadvl	acyl-Coenzyme A dehydrogenase, very long chain	0.013
Dgat2	diacylglycerol O-acyltransferase 2	0.013
Hsd17b4	hydroxysteroid (17-beta) dehydrogenase 4	0.013
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.013
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.013
Entpd5	ectonucleoside triphosphate diphosphohydrolase 5	0.013
Acot12	acyl-CoA thioesterase 12	0.013
Got2	glutamate oxaloacetate transaminase 2, mitochondrial	0.013
Pxmp2	peroxisomal membrane protein 2	0.013
Prdx3	peroxiredoxin 3	0.013
Vegfb	vascular endothelial growth factor B	0.013
Hoxb13	homeobox B13	0.013
Vdac2	voltage-dependent anion channel 2	0.013
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.013
Lonp1	lon peptidase 1, mitochondrial	0.013
Lhx1	LIM homeobox protein 1	0.013
Akr1d1	aldo-keto reductase family 1, member D1	0.013
Ldlr	low density lipoprotein receptor	0.013
Atp5g1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)	0.013
Pgm2	phosphoglucomutase 2	0.013
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.013
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.013
Orm3	orosomucoid 3	0.013
Fgl1	fibrinogen-like protein 1	0.013
Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	0.012
Slc25a11	solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11	0.012
Flg	filaggrin	0.012
Ugt3a2	UDP glycosyltransferases 3 family, polypeptide A2	0.012
Gsta3	glutathione S-transferase, alpha 3	0.012
Ivd	isovaleryl coenzyme A dehydrogenase	0.012
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.012
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.012
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.012
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.012
Lipe	lipase, hormone sensitive	0.012
Sds	serine dehydratase	0.012
Amhr2	anti-Mullerian hormone type 2 receptor	0.012
Fktn	fukutin	0.012
Acp6	acid phosphatase 6, lysophosphatidic	0.012
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.012
Acnat2	acyl-coenzyme A amino acid N-acyltransferase 2	0.012	Mouse
Slc29a1	solute carrier family 29 (nucleoside transporters), member 1	0.012
Fmo4	flavin containing monooxygenase 4	0.012
Parp16	poly (ADP-ribose) polymerase family, member 16	0.012
Apoo	apolipoprotein O	0.011
2010003K11Rik	RIKEN cDNA 2010003K11 gene	0.011
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.011
Acy3	aspartoacylase (aminoacylase) 3	0.011
D2hgdh	D-2-hydroxyglutarate dehydrogenase	0.011
Aldh4a1	aldehyde dehydrogenase 4 family, member A1	0.011	Yeast
Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	0.011
Lgals9	lectin, galactose binding, soluble 9	0.011
Nfs1	nitrogen fixation gene 1 (S. cerevisiae)	0.011
G6pc	glucose-6-phosphatase, catalytic	0.011
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.011
Ccbl2	cysteine conjugate-beta lyase 2	0.011
Pex11a	peroxisomal biogenesis factor 11 alpha	0.011
Kiss1	KiSS-1 metastasis-suppressor	0.011
Mog	myelin oligodendrocyte glycoprotein	0.011
AI317395	expressed sequence AI317395	0.011
2310061I04Rik	RIKEN cDNA 2310061I04 gene	0.011
Irgm2	immunity-related GTPase family M member 2	0.011
Acad11	acyl-Coenzyme A dehydrogenase family, member 11	0.011
Emx2	empty spiracles homolog 2 (Drosophila)	0.011
Epb4.1l4b	erythrocyte protein band 4.1-like 4b	0.011
Pdyn	prodynorphin	0.011
H2-D1	histocompatibility 2, D region locus 1	0.011
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.011
Bphl	biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen)	0.011
Fas	Fas (TNF receptor superfamily member 6)	0.011
Mdh2	malate dehydrogenase 2, NAD (mitochondrial)	0.011	Human
Dao	D-amino acid oxidase	0.011	Mouse
Pdhb	pyruvate dehydrogenase (lipoamide) beta	0.011
Masp2	mannan-binding lectin serine peptidase 2	0.011
Hspa9	heat shock protein 9	0.011
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	0.011
Slc12a5	solute carrier family 12, member 5	0.011
Myd88	myeloid differentiation primary response gene 88	0.011
Lyz2	lysozyme 2	0.011
Sardh	sarcosine dehydrogenase	0.011
Reep6	receptor accessory protein 6	0.010
Ak3	adenylate kinase 3	0.010
Cdhr5	cadherin-related family member 5	0.010
Atp5c1	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	0.010
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.010
Agxt2	alanine-glyoxylate aminotransferase 2	0.010
Fam151a	family with sequence simliarity 151, member A	0.010
Clybl	citrate lyase beta like	0.010
Ncoa3	nuclear receptor coactivator 3	0.010
Kif12	kinesin family member 12	0.010
Pipox	pipecolic acid oxidase	0.010
Ankrd43	ankyrin repeat domain 43	0.010
Dnaja3	DnaJ (Hsp40) homolog, subfamily A, member 3	0.010
Hao2	hydroxyacid oxidase 2	0.010
Cyp4f14	cytochrome P450, family 4, subfamily f, polypeptide 14	0.010
Cspg5	chondroitin sulfate proteoglycan 5	0.010
Cntnap1	contactin associated protein-like 1	0.010
Mocs1	molybdenum cofactor synthesis 1	0.010
Pdzk1	PDZ domain containing 1	0.010