IMP

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Mus musculus

1 genes annotated in mouse

ventral spinal cord interneuron fate determination

The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ventral spinal cord interneuron fate determination"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ventral spinal cord interneuron fate determination" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Hand2	heart and neural crest derivatives expressed transcript 2	0.999
Fgf8	fibroblast growth factor 8	0.998
Hand1	heart and neural crest derivatives expressed transcript 1	0.994
Mesp1	mesoderm posterior 1	0.926
Sox9	SRY-box containing gene 9	0.909
Pitx2	paired-like homeodomain transcription factor 2	0.897
Tbx1	T-box 1	0.896
Gata4	GATA binding protein 4	0.865
Foxc2	forkhead box C2	0.778
Fgfr2	fibroblast growth factor receptor 2	0.728
Isl1	ISL1 transcription factor, LIM/homeodomain	0.684
Nkx3-2	NK3 homeobox 2	0.680	Mouse
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.644	Mouse
Tbx5	T-box 5	0.628
Msx1	homeobox, msh-like 1	0.584
Otp	orthopedia homolog (Drosophila)	0.540
Gsc	goosecoid homeobox	0.512
Nog	noggin	0.501
Foxc1	forkhead box C1	0.489
Pax3	paired box gene 3	0.457
Pitx1	paired-like homeodomain transcription factor 1	0.453
Nkx6-1	NK6 homeobox 1	0.373
Tcfap2a	transcription factor AP-2, alpha	0.339
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.322	Mouse
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.318
Chrd	chordin	0.296
Rxra	retinoid X receptor alpha	0.289
Tgfb2	transforming growth factor, beta 2	0.286
Vax1	ventral anterior homeobox containing gene 1	0.266
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.265
Lhx3	LIM homeobox protein 3	0.242
Bmp4	bone morphogenetic protein 4	0.230
Otx2	orthodenticle homolog 2 (Drosophila)	0.213
Gli2	GLI-Kruppel family member GLI2	0.206
Lmx1b	LIM homeobox transcription factor 1 beta	0.202
Foxe3	forkhead box E3	0.201
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.196
Fgf3	fibroblast growth factor 3	0.194
Vegfa	vascular endothelial growth factor A	0.176
Atoh7	atonal homolog 7 (Drosophila)	0.170
Gja5	gap junction protein, alpha 5	0.170
Hoxa13	homeobox A13	0.152
Ntf3	neurotrophin 3	0.145
Pitx3	paired-like homeodomain transcription factor 3	0.142
Tlx2	T-cell leukemia, homeobox 2	0.142
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.139
Scn5a	sodium channel, voltage-gated, type V, alpha	0.138
Pax9	paired box gene 9	0.134
Barx1	BarH-like homeobox 1	0.128
Gipc3	GIPC PDZ domain containing family, member 3	0.125
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.121
Jag1	jagged 1	0.120
Odf3	outer dense fiber of sperm tails 3	0.116
Npas1	neuronal PAS domain protein 1	0.110
Omp	olfactory marker protein	0.106
Rara	retinoic acid receptor, alpha	0.102
Alx4	aristaless-like homeobox 4	0.097
Ucn	urocortin	0.097
Wnt3a	wingless-related MMTV integration site 3A	0.096
Hoxd3	homeobox D3	0.096
Sct	secretin	0.096
Col2a1	collagen, type II, alpha 1	0.094
Hoxd13	homeobox D13	0.091
Alx3	aristaless-like homeobox 3	0.091
Gata6	GATA binding protein 6	0.089
Hoxd12	homeobox D12	0.088
Rax	retina and anterior neural fold homeobox	0.079
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.078	Mouse
Ribc2	RIB43A domain with coiled-coils 2	0.077
Mzf1	myeloid zinc finger 1	0.077
Hist1h1t	histone cluster 1, H1t	0.077
Adam17	a disintegrin and metallopeptidase domain 17	0.075
Hoxa1	homeobox A1	0.073
Fgf17	fibroblast growth factor 17	0.072
Gh	growth hormone	0.072
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.066
Fgf10	fibroblast growth factor 10	0.066
Hes2	hairy and enhancer of split 2 (Drosophila)	0.064
Msx2	homeobox, msh-like 2	0.063
Nodal	nodal	0.063
Fgf22	fibroblast growth factor 22	0.062
Hmx1	H6 homeobox 1	0.062
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.061
Grid2ip	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1	0.061
Eya1	eyes absent 1 homolog (Drosophila)	0.061
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.060	Mouse
Rarb	retinoic acid receptor, beta	0.060
4930527J03Rik	RIKEN cDNA 4930527J03 gene	0.059
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.058
Hmx2	H6 homeobox 2	0.058
Gip	gastric inhibitory polypeptide	0.056
Sall4	sal-like 4 (Drosophila)	0.054
Cabp2	calcium binding protein 2	0.053
Tcf15	transcription factor 15	0.053
Hes3	hairy and enhancer of split 3 (Drosophila)	0.052
Rarg	retinoic acid receptor, gamma	0.051
Wnt6	wingless-related MMTV integration site 6	0.051
Cdx1	caudal type homeobox 1	0.049
Rsph6a	radial spoke head 6 homolog A (Chlamydomonas)	0.049
Znrf4	zinc and ring finger 4	0.049
Pdx1	pancreatic and duodenal homeobox 1	0.047
Avp	arginine vasopressin	0.046
Tssk1	testis-specific serine kinase 1	0.046
Btbd17	BTB (POZ) domain containing 17	0.045
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.044
Hoxd11	homeobox D11	0.044
Sox3	SRY-box containing gene 3	0.043
Spert	spermatid associated	0.043
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.043
Pyy	peptide YY	0.043
Dmrtb1	DMRT-like family B with proline-rich C-terminal, 1	0.042
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.042
Tlx3	T-cell leukemia, homeobox 3	0.042
Foxh1	forkhead box H1	0.041
Amh	anti-Mullerian hormone	0.041
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.041
Tbx3	T-box 3	0.040
Neurog1	neurogenin 1	0.040
Evx2	even skipped homeotic gene 2 homolog	0.039
Lhx5	LIM homeobox protein 5	0.039
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.039
Onecut3	one cut domain, family member 3	0.038
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.037
Foxb2	forkhead box B2	0.037
Dlx5	distal-less homeobox 5	0.037
Bdkrb2	bradykinin receptor, beta 2	0.036
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.035
Smo	smoothened homolog (Drosophila)	0.035
Utf1	undifferentiated embryonic cell transcription factor 1	0.035
Fgfrl1	fibroblast growth factor receptor-like 1	0.034
Socs1	suppressor of cytokine signaling 1	0.034
Pax6	paired box gene 6	0.034
BC057022	cDNA sequence BC057022	0.034
Sycn	syncollin	0.033
Fgfr1	fibroblast growth factor receptor 1	0.033
Gjc2	gap junction protein, gamma 2	0.032
Fgf15	fibroblast growth factor 15	0.032
Ltb	lymphotoxin B	0.031
Foxb1	forkhead box B1	0.031
Pth2	parathyroid hormone 2	0.031
Egr4	early growth response 4	0.031
Hoxb13	homeobox B13	0.030
Rhcg	Rhesus blood group-associated C glycoprotein	0.030
Spdef	SAM pointed domain containing ets transcription factor	0.030
Gbx2	gastrulation brain homeobox 2	0.030
Ece1	endothelin converting enzyme 1	0.030
Dscaml1	Down syndrome cell adhesion molecule-like 1	0.029
Foxg1	forkhead box G1	0.029
Col22a1	collagen, type XXII, alpha 1	0.029
1700029H14Rik	RIKEN cDNA 1700029H14 gene	0.029
Emx1	empty spiracles homolog 1 (Drosophila)	0.029
Prm1	protamine 1	0.028
Zfp444	zinc finger protein 444	0.028
Prrx1	paired related homeobox 1	0.027
Fgfr3	fibroblast growth factor receptor 3	0.027
Ptf1a	pancreas specific transcription factor, 1a	0.027
Etv2	ets variant gene 2	0.027
Shank1	SH3/ankyrin domain gene 1	0.027
Sox4	SRY-box containing gene 4	0.026
Pou4f3	POU domain, class 4, transcription factor 3	0.026
Bmp8b	bone morphogenetic protein 8b	0.026
Nrtn	neurturin	0.025
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.025
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.025
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.025	Mouse
Ret	ret proto-oncogene	0.025
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.024
T	brachyury	0.024
Oprd1	opioid receptor, delta 1	0.024
Sox1	SRY-box containing gene 1	0.024
Hoxa3	homeobox A3	0.024
Msgn1	mesogenin 1	0.024
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.024
Sall3	sal-like 3 (Drosophila)	0.024
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.024
Gja1	gap junction protein, alpha 1	0.023
Mesp2	mesoderm posterior 2	0.023
Bhlhe23	basic helix-loop-helix family, member e23	0.023
Ankrd2	ankyrin repeat domain 2 (stretch responsive muscle)	0.022
Barx2	BarH-like homeobox 2	0.022
Oc90	otoconin 90	0.022
Ighmbp2	immunoglobulin mu binding protein 2	0.022
Zscan2	zinc finger and SCAN domain containing 2	0.022
Adra1b	adrenergic receptor, alpha 1b	0.021
Neurog3	neurogenin 3	0.021
Pax1	paired box gene 1	0.021
Defa-rs12	defensin, alpha, related sequence 12	0.021
Efnb2	ephrin B2	0.021
Ppy	pancreatic polypeptide	0.020
Foxa2	forkhead box A2	0.020
Pou3f4	POU domain, class 3, transcription factor 4	0.020
Acvr1	activin A receptor, type 1	0.020
Lactbl1	lactamase, beta-like 1	0.020
Defa-rs2	defensin, alpha, related sequence 2	0.020
6030468B19Rik	RIKEN cDNA 6030468B19 gene	0.019
1700008P20Rik	RIKEN cDNA 1700008P20 gene	0.019
Prop1	paired like homeodomain factor 1	0.019
Pax2	paired box gene 2	0.019
Zfpm2	zinc finger protein, multitype 2	0.019
Ms4a15	membrane-spanning 4-domains, subfamily A, member 15	0.019
Chrm4	cholinergic receptor, muscarinic 4	0.019
Hoxa7	homeobox A7	0.019
Fgf16	fibroblast growth factor 16	0.018
Lmx1a	LIM homeobox transcription factor 1 alpha	0.018
Fam65c	family with sequence similarity 65, member C	0.018
Prss44	protease, serine, 44	0.018
1700011A15Rik	RIKEN cDNA 1700011A15 gene	0.018
Krt16	keratin 16	0.018
Kcnk3	potassium channel, subfamily K, member 3	0.018
Guca2b	guanylate cyclase activator 2b (retina)	0.018
Sstr3	somatostatin receptor 3	0.018
Dmbx1	diencephalon/mesencephalon homeobox 1	0.018
Ccr10	chemokine (C-C motif) receptor 10	0.017
Vangl2	vang-like 2 (van gogh, Drosophila)	0.017
Rhox6	reproductive homeobox 6	0.017
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.017
Insm1	insulinoma-associated 1	0.017
Gli3	GLI-Kruppel family member GLI3	0.017
Dlx6	distal-less homeobox 6	0.017
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.017
1700065I17Rik	RIKEN cDNA 1700065I17 gene	0.017
Foxn4	forkhead box N4	0.017
Fbll1	fibrillarin-like 1	0.017
Cdh15	cadherin 15	0.016
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.016
Sox11	SRY-box containing gene 11	0.016
Bmp7	bone morphogenetic protein 7	0.016
Sac3d1	SAC3 domain containing 1	0.016
4921517D21Rik	RIKEN cDNA 4921517D21 gene	0.016
Tlx1	T-cell leukemia, homeobox 1	0.015
Pax4	paired box gene 4	0.015
Gpr27	G protein-coupled receptor 27	0.015
Sftpb	surfactant associated protein B	0.015
Pthlh	parathyroid hormone-like peptide	0.015
Krt15	keratin 15	0.015
Tcam1	testicular cell adhesion molecule 1	0.015
Theg	testicular haploid expressed gene	0.015
Klhl35	kelch-like 35 (Drosophila)	0.015
Hcrt	hypocretin	0.015
Pnoc	prepronociceptin	0.015
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.015
Tgfbr2	transforming growth factor, beta receptor II	0.015
Pou2f2	POU domain, class 2, transcription factor 2	0.014
Zeb1	zinc finger E-box binding homeobox 1	0.014
Bmp10	bone morphogenetic protein 10	0.014
Dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.014
Sox14	SRY-box containing gene 14	0.014
Allc	allantoicase	0.014
Foxd2	forkhead box D2	0.014
Myl3	myosin, light polypeptide 3	0.014
Gp9	glycoprotein 9 (platelet)	0.014
Dlx2	distal-less homeobox 2	0.014
Trh	thyrotropin releasing hormone	0.014
4930404N11Rik	RIKEN cDNA 4930404N11 gene	0.014
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.014
1700018B08Rik	RIKEN cDNA 1700018B08 gene	0.014
Cort	cortistatin	0.013
Slurp1	secreted Ly6/Plaur domain containing 1	0.013
Arx	aristaless related homeobox	0.013
Cabp7	calcium binding protein 7	0.013
Sp6	trans-acting transcription factor 6	0.013
Cfc1	cripto, FRL-1, cryptic family 1	0.013
Mmp24	matrix metallopeptidase 24	0.013
Zg16	zymogen granule protein 16	0.013
H1foo	H1 histone family, member O, oocyte-specific	0.013
Foxe1	forkhead box E1	0.013
Prrx2	paired related homeobox 2	0.013
Tg	thyroglobulin	0.013
Uncx	UNC homeobox	0.013
Tcf21	transcription factor 21	0.013
Cryba2	crystallin, beta A2	0.013
Galr3	galanin receptor 3	0.013
Foxl2	forkhead box L2	0.013
Nobox	NOBOX oogenesis homeobox	0.013
Dlx1	distal-less homeobox 1	0.013
BC024139	cDNA sequence BC024139	0.013
Tll2	tolloid-like 2	0.013
Nos3	nitric oxide synthase 3, endothelial cell	0.013
Cdx2	caudal type homeobox 2	0.013
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.012
Mdfi	MyoD family inhibitor	0.012
Mmel1	membrane metallo-endopeptidase-like 1	0.012
Fgf21	fibroblast growth factor 21	0.012
Mybpc3	myosin binding protein C, cardiac	0.012
Tsx	testis specific X-linked gene	0.012
Tas1r1	taste receptor, type 1, member 1	0.012
Pax8	paired box gene 8	0.012
1700001O22Rik	RIKEN cDNA 1700001O22 gene	0.012
Rtn4r	reticulon 4 receptor	0.012
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.012
Papln	papilin, proteoglycan-like sulfated glycoprotein	0.012
Xirp1	xin actin-binding repeat containing 1	0.012
Tssk3	testis-specific serine kinase 3	0.012
Gja8	gap junction protein, alpha 8	0.011
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.011
Art5	ADP-ribosyltransferase 5	0.011
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.011
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.011
Hoxc9	homeobox C9	0.011
Cela3b	chymotrypsin-like elastase family, member 3B	0.011
Fut7	fucosyltransferase 7	0.011
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.011
Sox10	SRY-box containing gene 10	0.011
Gucy2e	guanylate cyclase 2e	0.011
Isl2	insulin related protein 2 (islet 2)	0.011
Lhx4	LIM homeobox protein 4	0.011
Gata5	GATA binding protein 5	0.011
Dusp13	dual specificity phosphatase 13	0.011
Ntn3	netrin 3	0.011
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.011
Plekhg6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.011
Figla	folliculogenesis specific basic helix-loop-helix	0.011
Mnx1	motor neuron and pancreas homeobox 1	0.010
Wap	whey acidic protein	0.010
Slc26a5	solute carrier family 26, member 5	0.010
Foxd3	forkhead box D3	0.010
Padi1	peptidyl arginine deiminase, type I	0.010
Sfpi1	SFFV proviral integration 1	0.010
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.010
Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3	0.010
Glis1	GLIS family zinc finger 1	0.010
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.010
Best2	bestrophin 2	0.010
Syngr4	synaptogyrin 4	0.010
Gjb4	gap junction protein, beta 4	0.010
Gzmm	granzyme M (lymphocyte met-ase 1)	0.010
Ctnnb1	catenin (cadherin associated protein), beta 1	0.010
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.010
Rhpn1	rhophilin, Rho GTPase binding protein 1	0.010