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Process View

Mus musculus

1 genes annotated in mouse

renal capsule formation

The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "renal capsule formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "renal capsule formation" (in gray)

Name	Description	Probability	Func Analog Organism
Pax2	paired box gene 2	1.000
Fgfr2	fibroblast growth factor receptor 2	0.999
Tbx1	T-box 1	0.999
Eya1	eyes absent 1 homolog (Drosophila)	0.993
Foxc2	forkhead box C2	0.986	Mouse
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.986
Fgf8	fibroblast growth factor 8	0.984
Shh	sonic hedgehog	0.982
Hoxa1	homeobox A1	0.979
Otx2	orthodenticle homolog 2 (Drosophila)	0.964
Bmp4	bone morphogenetic protein 4	0.942
Gbx2	gastrulation brain homeobox 2	0.941
Pax3	paired box gene 3	0.932
Pitx2	paired-like homeodomain transcription factor 2	0.920
Tcfap2a	transcription factor AP-2, alpha	0.917
Hmx3	H6 homeobox 3	0.905
Foxc1	forkhead box C1	0.900	Mouse
Hand2	heart and neural crest derivatives expressed transcript 2	0.869
Gli3	GLI-Kruppel family member GLI3	0.856
Jag1	jagged 1	0.792
Tgfb2	transforming growth factor, beta 2	0.751
Lmx1a	LIM homeobox transcription factor 1 alpha	0.746
Foxa2	forkhead box A2	0.726	Mouse
Dlx5	distal-less homeobox 5	0.714
Chd7	chromodomain helicase DNA binding protein 7	0.710
Msx1	homeobox, msh-like 1	0.650
Pax6	paired box gene 6	0.647
Foxg1	forkhead box G1	0.643	Mouse
Gsc	goosecoid homeobox	0.637
Lmx1b	LIM homeobox transcription factor 1 beta	0.636
Prrx2	paired related homeobox 2	0.602
Pax8	paired box gene 8	0.585
Otx1	orthodenticle homolog 1 (Drosophila)	0.577
Hoxa3	homeobox A3	0.568
Fgfr3	fibroblast growth factor receptor 3	0.552
Hand1	heart and neural crest derivatives expressed transcript 1	0.474
Rarb	retinoic acid receptor, beta	0.428
Rarg	retinoic acid receptor, gamma	0.427
Tbx10	T-box 10	0.411
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.392
Hoxd3	homeobox D3	0.374
Hoxa2	homeobox A2	0.351
Ednra	endothelin receptor type A	0.349
Prrx1	paired related homeobox 1	0.346
Fgf3	fibroblast growth factor 3	0.326
Efnb2	ephrin B2	0.325
Smo	smoothened homolog (Drosophila)	0.323
Lhx1	LIM homeobox protein 1	0.302
Nog	noggin	0.292
Mesp1	mesoderm posterior 1	0.257
Zeb1	zinc finger E-box binding homeobox 1	0.255
Sox2	SRY-box containing gene 2	0.254
Vax1	ventral anterior homeobox containing gene 1	0.247
Pax9	paired box gene 9	0.239
Chrd	chordin	0.231
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.225
Wnt1	wingless-related MMTV integration site 1	0.224
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.217
Emx2	empty spiracles homolog 2 (Drosophila)	0.197
Vangl2	vang-like 2 (van gogh, Drosophila)	0.177
Neurog1	neurogenin 1	0.164
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.158
Gata4	GATA binding protein 4	0.158
Ntf3	neurotrophin 3	0.157
Nkx3-2	NK3 homeobox 2	0.156
Isl1	ISL1 transcription factor, LIM/homeodomain	0.155
Hoxd11	homeobox D11	0.144
Hmx1	H6 homeobox 1	0.142
Cdx1	caudal type homeobox 1	0.137
En1	engrailed 1	0.131
Fgfr1	fibroblast growth factor receptor 1	0.130
Alx4	aristaless-like homeobox 4	0.128
Pou4f2	POU domain, class 4, transcription factor 2	0.119
T	brachyury	0.116
Matn3	matrilin 3	0.115
Pou4f3	POU domain, class 4, transcription factor 3	0.115
Bmp7	bone morphogenetic protein 7	0.115
Msx2	homeobox, msh-like 2	0.114
Fgf10	fibroblast growth factor 10	0.107
Foxh1	forkhead box H1	0.106
Vegfa	vascular endothelial growth factor A	0.105
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.104
Gdnf	glial cell line derived neurotrophic factor	0.104
Hoxd9	homeobox D9	0.097
Nkx2-1	NK2 homeobox 1	0.093
Foxf2	forkhead box F2	0.088
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.088
Foxb1	forkhead box B1	0.088
Hoxb3	homeobox B3	0.087
Atoh1	atonal homolog 1 (Drosophila)	0.085
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.083
Gli2	GLI-Kruppel family member GLI2	0.080
Foxa1	forkhead box A1	0.080	Mouse
Amh	anti-Mullerian hormone	0.078
Evx2	even skipped homeotic gene 2 homolog	0.075
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.074
Hmx2	H6 homeobox 2	0.073
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.072
Foxe3	forkhead box E3	0.071	Mouse
Tlx3	T-cell leukemia, homeobox 3	0.068
Adra2b	adrenergic receptor, alpha 2b	0.067
Meox2	mesenchyme homeobox 2	0.066
Sox9	SRY-box containing gene 9	0.063
Hoxa9	homeobox A9	0.061
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.061
Pitx3	paired-like homeodomain transcription factor 3	0.059
Pbx1	pre B-cell leukemia transcription factor 1	0.057
Tshz1	teashirt zinc finger family member 1	0.057
Pdx1	pancreatic and duodenal homeobox 1	0.053
Ihh	Indian hedgehog	0.051
Hoxb1	homeobox B1	0.050
Sox3	SRY-box containing gene 3	0.050
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.049
Cldn3	claudin 3	0.048
Hoxa4	homeobox A4	0.048
Bnc1	basonuclin 1	0.048
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.047
Gata3	GATA binding protein 3	0.047
Emx1	empty spiracles homolog 1 (Drosophila)	0.046
Wt1	Wilms tumor 1 homolog	0.046
Hoxb6	homeobox B6	0.045
Fgf4	fibroblast growth factor 4	0.044
Wnt7a	wingless-related MMTV integration site 7A	0.041
Tcf21	transcription factor 21	0.038
Hoxb13	homeobox B13	0.038
Hoxd13	homeobox D13	0.038
Hoxc8	homeobox C8	0.037
Figla	folliculogenesis specific basic helix-loop-helix	0.036
Gata6	GATA binding protein 6	0.036
Rxra	retinoid X receptor alpha	0.036
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.035
Tmprss2	transmembrane protease, serine 2	0.035
Dlx2	distal-less homeobox 2	0.035
Onecut1	one cut domain, family member 1	0.035
Phlda2	pleckstrin homology-like domain, family A, member 2	0.034
Dmrt3	doublesex and mab-3 related transcription factor 3	0.034
Hoxb9	homeobox B9	0.034
Ece1	endothelin converting enzyme 1	0.034
Olfr70	olfactory receptor 70	0.034
Wnt3a	wingless-related MMTV integration site 3A	0.034
Hoxc6	homeobox C6	0.033
Slc26a4	solute carrier family 26, member 4	0.033
Myod1	myogenic differentiation 1	0.032
Emid2	EMI domain containing 2	0.032
Klk4	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	0.032
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.032
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.031
Mycs	myc-like oncogene, s-myc protein	0.030
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.030
Hoxd1	homeobox D1	0.029
Pax1	paired box gene 1	0.029
Hmga2	high mobility group AT-hook 2	0.028
Tlx2	T-cell leukemia, homeobox 2	0.028
Ctnnb1	catenin (cadherin associated protein), beta 1	0.028
Etv2	ets variant gene 2	0.028
Nodal	nodal	0.028
Hoxb5	homeobox B5	0.027
Pitx1	paired-like homeodomain transcription factor 1	0.027
Sall3	sal-like 3 (Drosophila)	0.026
Hoxa10	homeobox A10	0.026
Evx1	even skipped homeotic gene 1 homolog	0.026
Kremen2	kringle containing transmembrane protein 2	0.026
Apob	apolipoprotein B	0.026
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.025
Hoxb2	homeobox B2	0.025
Hoxd10	homeobox D10	0.025
Hes5	hairy and enhancer of split 5 (Drosophila)	0.025
Foxi3	forkhead box I3	0.025
Mecom	MDS1 and EVI1 complex locus	0.025
Sall4	sal-like 4 (Drosophila)	0.025
Il25	interleukin 25	0.025
Pax7	paired box gene 7	0.024
Ush1g	Usher syndrome 1G homolog (human)	0.024
Elf3	E74-like factor 3	0.024
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.023
Zic1	zinc finger protein of the cerebellum 1	0.023
Pcdh12	protocadherin 12	0.023
Cldn8	claudin 8	0.022
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.022
BC057022	cDNA sequence BC057022	0.022
Fgf15	fibroblast growth factor 15	0.022
Vsx2	visual system homeobox 2	0.022
Irx1	Iroquois related homeobox 1 (Drosophila)	0.022
Alx1	ALX homeobox 1	0.021
Notch1	Notch gene homolog 1 (Drosophila)	0.021
Lyzl4	lysozyme-like 4	0.021
Hoxa11	homeobox A11	0.021
Hnf1b	HNF1 homeobox B	0.021
Hoxd4	homeobox D4	0.021
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.021
Tbx2	T-box 2	0.021
Adam17	a disintegrin and metallopeptidase domain 17	0.020
Rdh10	retinol dehydrogenase 10 (all-trans)	0.020
Myo15	myosin XV	0.020
Hoxb8	homeobox B8	0.020
F12	coagulation factor XII (Hageman factor)	0.020
Dhh	desert hedgehog	0.019
Rax	retina and anterior neural fold homeobox	0.019
Pou2f3	POU domain, class 2, transcription factor 3	0.019
Vax2	ventral anterior homeobox containing gene 2	0.018
Hes1	hairy and enhancer of split 1 (Drosophila)	0.018
Sox7	SRY-box containing gene 7	0.018
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.018
Hnf4a	hepatic nuclear factor 4, alpha	0.018
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.018
Nobox	NOBOX oogenesis homeobox	0.018
Nrtn	neurturin	0.018
Zfp771	zinc finger protein 771	0.018
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.018
Gsx1	GS homeobox 1	0.018
Theg	testicular haploid expressed gene	0.017
Mip	major intrinsic protein of eye lens fiber	0.017
Tgfbr2	transforming growth factor, beta receptor II	0.017
Psen1	presenilin 1	0.017
Sftpb	surfactant associated protein B	0.017
Zic3	zinc finger protein of the cerebellum 3	0.016
Fev	FEV (ETS oncogene family)	0.016
Tmem30b	transmembrane protein 30B	0.016
Sox1	SRY-box containing gene 1	0.016
Fgfr4	fibroblast growth factor receptor 4	0.016
Lhx3	LIM homeobox protein 3	0.016
Crb2	crumbs homolog 2 (Drosophila)	0.016
Wnt9b	wingless-type MMTV integration site 9B	0.016
Tead3	TEA domain family member 3	0.016
Foxd3	forkhead box D3	0.016	Mouse
Tbx15	T-box 15	0.016
Onecut3	one cut domain, family member 3	0.015
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.015
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.015
Myf5	myogenic factor 5	0.015
Cldn2	claudin 2	0.015
Hoxb7	homeobox B7	0.015
G6pc2	glucose-6-phosphatase, catalytic, 2	0.015
Dmgdh	dimethylglycine dehydrogenase precursor	0.015
Mn1	meningioma 1	0.015
Mnx1	motor neuron and pancreas homeobox 1	0.015
Lefty1	left right determination factor 1	0.015
Foxn4	forkhead box N4	0.015
Lhx5	LIM homeobox protein 5	0.015
Uncx	UNC homeobox	0.014
Gjd3	gap junction protein, delta 3	0.014
Sall1	sal-like 1 (Drosophila)	0.014
Scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.014
Foxl1	forkhead box L1	0.014
Bik	BCL2-interacting killer	0.014
Dlx6	distal-less homeobox 6	0.014
Prm1	protamine 1	0.014
Snai1	snail homolog 1 (Drosophila)	0.014
Cel	carboxyl ester lipase	0.014
Myog	myogenin	0.014
Mlph	melanophilin	0.014
Foxq1	forkhead box Q1	0.014	Mouse
Hes3	hairy and enhancer of split 3 (Drosophila)	0.014
Ccdc96	coiled-coil domain containing 96	0.014
Krt8	keratin 8	0.014
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.014
Col17a1	collagen, type XVII, alpha 1	0.013
Tcl1	T-cell lymphoma breakpoint 1	0.013
Nccrp1	non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)	0.013
Bdnf	brain derived neurotrophic factor	0.013
Hoxd8	homeobox D8	0.013
Marveld3	MARVEL (membrane-associating) domain containing 3	0.013
Sost	sclerostin	0.013
Tal2	T-cell acute lymphocytic leukemia 2	0.013
Lhb	luteinizing hormone beta	0.013
Inhbe	inhibin beta E	0.013
Irx3	Iroquois related homeobox 3 (Drosophila)	0.013
Gdf15	growth differentiation factor 15	0.013
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.013
Mdfi	MyoD family inhibitor	0.013
Zic2	zinc finger protein of the cerebellum 2	0.013
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.013
Gjb3	gap junction protein, beta 3	0.013
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.013
Gpr50	G-protein-coupled receptor 50	0.013
BC021785	cDNA sequence BC021785	0.013
Fshr	follicle stimulating hormone receptor	0.012
Foxd4	forkhead box D4	0.012	Mouse
Apoa5	apolipoprotein A-V	0.012
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.012
Nkx6-1	NK6 homeobox 1	0.012
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.012
Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	0.012
Fam65c	family with sequence similarity 65, member C	0.012
Gjb4	gap junction protein, beta 4	0.012
Spdef	SAM pointed domain containing ets transcription factor	0.012
Twist2	twist homolog 2 (Drosophila)	0.012
Cdx2	caudal type homeobox 2	0.012
Foxl2	forkhead box L2	0.012	Mouse
Ambn	ameloblastin	0.012
Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	0.012
Il11	interleukin 11	0.012
Socs1	suppressor of cytokine signaling 1	0.012
Lrp2	low density lipoprotein receptor-related protein 2	0.012
Hmga1	high mobility group AT-hook 1	0.012
Epha8	Eph receptor A8	0.012
C77080	expressed sequence C77080	0.012
Uroc1	urocanase domain containing 1	0.012
2610109H07Rik	RIKEN cDNA 2610109H07 gene	0.011
Smad6	MAD homolog 6 (Drosophila)	0.011
Cldn4	claudin 4	0.011
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.011
S1pr2	sphingosine-1-phosphate receptor 2	0.011
Myo6	myosin VI	0.011
Ptk7	PTK7 protein tyrosine kinase 7	0.011
Sox11	SRY-box containing gene 11	0.011
Crb3	crumbs homolog 3 (Drosophila)	0.011
Sox14	SRY-box containing gene 14	0.011
Hpx	hemopexin	0.011
Foxi1	forkhead box I1	0.011	Mouse
Sim1	single-minded homolog 1 (Drosophila)	0.011
Col13a1	collagen, type XIII, alpha 1	0.011
Fzd10	frizzled homolog 10 (Drosophila)	0.011
Sim2	single-minded homolog 2 (Drosophila)	0.011
En2	engrailed 2	0.011
Aqp2	aquaporin 2	0.011
Col22a1	collagen, type XXII, alpha 1	0.011
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.011
Barx1	BarH-like homeobox 1	0.011
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.011
Phox2b	paired-like homeobox 2b	0.011
Mapk15	mitogen-activated protein kinase 15	0.011
Wnt6	wingless-related MMTV integration site 6	0.011
Pou5f1	POU domain, class 5, transcription factor 1	0.011
F2	coagulation factor II	0.011
Acvr1	activin A receptor, type 1	0.011
Otp	orthopedia homolog (Drosophila)	0.010
Wnt2b	wingless related MMTV integration site 2b	0.010
Srrm4	serine/arginine repetitive matrix 4	0.010
Slc18a3	solute carrier family 18 (vesicular monoamine), member 3	0.010
Mep1a	meprin 1 alpha	0.010
Flt4	FMS-like tyrosine kinase 4	0.010
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.010
Rara	retinoic acid receptor, alpha	0.010
Tulp2	tubby-like protein 2	0.010
Cldn6	claudin 6	0.010
Barhl1	BarH-like 1 (Drosophila)	0.010
BC024139	cDNA sequence BC024139	0.010
Bdkrb2	bradykinin receptor, beta 2	0.010
Rtn4rl2	reticulon 4 receptor-like 2	0.010