IMP

Process View

Mus musculus

13 genes annotated in mouse

cellular response to corticosteroid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to corticosteroid stimulus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to corticosteroid stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.726	Mouse
Vegfa	vascular endothelial growth factor A	0.703
Tgfb1	transforming growth factor, beta 1	0.536	Mouse Rat
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.530
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.506
Trim55	tripartite motif-containing 55	0.407	Mouse
Ptgs2	prostaglandin-endoperoxide synthase 2	0.342
Pax3	paired box gene 3	0.326
Stat3	signal transducer and activator of transcription 3	0.281
Ren1	renin 1 structural	0.279
Tgfbr2	transforming growth factor, beta receptor II	0.265
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.232
Lyz2	lysozyme 2	0.210
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.196
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.178
Lepr	leptin receptor	0.159
Lep	leptin	0.155
Trim63	tripartite motif-containing 63	0.136
Pitx2	paired-like homeodomain transcription factor 2	0.135
Casp1	caspase 1	0.130	Mouse
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.128
Trp53	transformation related protein 53	0.124
Foxc1	forkhead box C1	0.097
Osmr	oncostatin M receptor	0.095
Esr1	estrogen receptor 1 (alpha)	0.095
Fbn1	fibrillin 1	0.087
Gbp5	guanylate binding protein 5	0.084
Myog	myogenin	0.082	Mouse
Slc12a1	solute carrier family 12, member 1	0.082
Hif1a	hypoxia inducible factor 1, alpha subunit	0.081
Dmd	dystrophin, muscular dystrophy	0.079
Shh	sonic hedgehog	0.079
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.078
Gata4	GATA binding protein 4	0.077
Aim2	absent in melanoma 2	0.075
Il18	interleukin 18	0.071
Fgfr2	fibroblast growth factor receptor 2	0.071
Hand2	heart and neural crest derivatives expressed transcript 2	0.071
Ghr	growth hormone receptor	0.070
Prlr	prolactin receptor	0.066
Zeb1	zinc finger E-box binding homeobox 1	0.064
Csf1	colony stimulating factor 1 (macrophage)	0.060
Meox2	mesenchyme homeobox 2	0.059
Pax7	paired box gene 7	0.053
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.052
Fas	Fas (TNF receptor superfamily member 6)	0.051
Nos3	nitric oxide synthase 3, endothelial cell	0.051
Pomc	pro-opiomelanocortin-alpha	0.047
Lox	lysyl oxidase	0.047
Tnni2	troponin I, skeletal, fast 2	0.046
Wwox	WW domain-containing oxidoreductase	0.045
Agtr1a	angiotensin II receptor, type 1a	0.045	Rat
Errfi1	ERBB receptor feedback inhibitor 1	0.043
Foxp3	forkhead box P3	0.042
Kit	kit oncogene	0.041
Esr2	estrogen receptor 2 (beta)	0.039
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.036
Il1b	interleukin 1 beta	0.035
Il6st	interleukin 6 signal transducer	0.034
Fst	follistatin	0.033
Jak2	Janus kinase 2	0.033
Vdr	vitamin D receptor	0.032
Pycard	PYD and CARD domain containing	0.031
Htt	huntingtin	0.031
Nos1	nitric oxide synthase 1, neuronal	0.031
Arnt	aryl hydrocarbon receptor nuclear translocator	0.030
Prrx1	paired related homeobox 1	0.030
Apc	adenomatosis polyposis coli	0.030
Akr1c6	aldo-keto reductase family 1, member C6	0.029
Socs5	suppressor of cytokine signaling 5	0.027
Rb1	retinoblastoma 1	0.027
Rora	RAR-related orphan receptor alpha	0.026
Il1r1	interleukin 1 receptor, type I	0.025
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.025
Bdkrb2	bradykinin receptor, beta 2	0.025
Hsd3b6	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6	0.025	Rat
Bmp2	bone morphogenetic protein 2	0.025
Myod1	myogenic differentiation 1	0.024
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.024
Fbxo32	F-box protein 32	0.023
H2-Eb1	histocompatibility 2, class II antigen E beta	0.022
Fgfr1	fibroblast growth factor receptor 1	0.022
Hbegf	heparin-binding EGF-like growth factor	0.022
Nf1	neurofibromatosis 1	0.021
Pparg	peroxisome proliferator activated receptor gamma	0.021
Ccl2	chemokine (C-C motif) ligand 2	0.021
Mstn	myostatin	0.021
Myf5	myogenic factor 5	0.021	Mouse
Wfikkn2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.021
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.021
Ar	androgen receptor	0.021
F13b	coagulation factor XIII, beta subunit	0.020
Ece1	endothelin converting enzyme 1	0.020
Tgfb2	transforming growth factor, beta 2	0.020	Mouse
Csf1r	colony stimulating factor 1 receptor	0.020
Kiss1	KiSS-1 metastasis-suppressor	0.020
Dysf	dysferlin	0.020
Pten	phosphatase and tensin homolog	0.018
Cav1	caveolin 1, caveolae protein	0.018
Plau	plasminogen activator, urokinase	0.018
Ednra	endothelin receptor type A	0.018
Vav3	vav 3 oncogene	0.018
Msx1	homeobox, msh-like 1	0.018
Ret	ret proto-oncogene	0.017
Mybph	myosin binding protein H	0.017
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.016
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.016	Rat
Smad3	MAD homolog 3 (Drosophila)	0.016
Eif3f	eukaryotic translation initiation factor 3, subunit F	0.016
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.016
Myf6	myogenic factor 6	0.016	Mouse
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.015
Tgfbr1	transforming growth factor, beta receptor I	0.015
Tfpi2	tissue factor pathway inhibitor 2	0.015
Stat5a	signal transducer and activator of transcription 5A	0.015
Nanog	Nanog homeobox	0.015
Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	0.015	Rat
Rxra	retinoid X receptor alpha	0.015
Drd2	dopamine receptor D2	0.015
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.014
Hoxd8	homeobox D8	0.014
Thbs1	thrombospondin 1	0.014
Keg1	kidney expressed gene 1	0.014
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.014
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.014
Msx2	homeobox, msh-like 2	0.014
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.014
Fgf10	fibroblast growth factor 10	0.014
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.014
Rarb	retinoic acid receptor, beta	0.013
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.013
Emp1	epithelial membrane protein 1	0.013
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.013
Otc	ornithine transcarbamylase	0.013
Col1a1	collagen, type I, alpha 1	0.013
Cxcl1	chemokine (C-X-C motif) ligand 1	0.013
Vhl	von Hippel-Lindau tumor suppressor	0.013
Dsg4	desmoglein 4	0.013
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.012
Apaf1	apoptotic peptidase activating factor 1	0.012
Foxc2	forkhead box C2	0.012
Sox9	SRY-box containing gene 9	0.012
Xirp1	xin actin-binding repeat containing 1	0.012
Cyp2j5	cytochrome P450, family 2, subfamily j, polypeptide 5	0.012
Myc	myelocytomatosis oncogene	0.012
Cyld	cylindromatosis (turban tumor syndrome)	0.012
Glyat	glycine-N-acyltransferase	0.011
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.011
Klhl24	kelch-like 24 (Drosophila)	0.011
Arx	aristaless related homeobox	0.011
Htra3	HtrA serine peptidase 3	0.011
Hrc	histidine rich calcium binding protein	0.011
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.011
Klf6	Kruppel-like factor 6	0.011
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.011
Egfr	epidermal growth factor receptor	0.011	Rat
Ifngr1	interferon gamma receptor 1	0.011
Gm4788	predicted gene 4788	0.011
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.011
Il1a	interleukin 1 alpha	0.011
Fshr	follicle stimulating hormone receptor	0.011
Jag1	jagged 1	0.011
Pla2r1	phospholipase A2 receptor 1	0.011
Gna13	guanine nucleotide binding protein, alpha 13	0.011
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.011
Pax6	paired box gene 6	0.011
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.011
Mesp1	mesoderm posterior 1	0.010
Nr3c2	nuclear receptor subfamily 3, group C, member 2	0.010	Mouse
Prl	prolactin	0.010
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.010	Rat
Foxn1	forkhead box N1	0.010