IMP

Process View

Mus musculus

1 genes annotated in mouse

neural fold elevation formation

The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neural fold elevation formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "neural fold elevation formation" (in gray)

Name	Description	Probability	Func Analog Organism
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.844
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.673
Ctnnb1	catenin (cadherin associated protein), beta 1	0.633
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.590
Nos3	nitric oxide synthase 3, endothelial cell	0.585
Otp	orthopedia homolog (Drosophila)	0.525
Egln1	EGL nine homolog 1 (C. elegans)	0.455
Fgf8	fibroblast growth factor 8	0.452
Gdnf	glial cell line derived neurotrophic factor	0.367
Vegfa	vascular endothelial growth factor A	0.361
Egfr	epidermal growth factor receptor	0.337
Gli3	GLI-Kruppel family member GLI3	0.324
Pten	phosphatase and tensin homolog	0.319
Spry4	sprouty homolog 4 (Drosophila)	0.274
Foxd2	forkhead box D2	0.273
Gpr50	G-protein-coupled receptor 50	0.251
Lepr	leptin receptor	0.227
Fgfr2	fibroblast growth factor receptor 2	0.222
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.218
Sim1	single-minded homolog 1 (Drosophila)	0.214	Mouse
Pitx2	paired-like homeodomain transcription factor 2	0.199
Grid1	glutamate receptor, ionotropic, delta 1	0.181
Wnt1	wingless-related MMTV integration site 1	0.171
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.169
Efna2	ephrin A2	0.168
Efnb2	ephrin B2	0.161
Sim2	single-minded homolog 2 (Drosophila)	0.160	Mouse
Epas1	endothelial PAS domain protein 1	0.152	Mouse
Hoxd13	homeobox D13	0.143
Adam17	a disintegrin and metallopeptidase domain 17	0.136
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.131
Sox9	SRY-box containing gene 9	0.131
Foxc1	forkhead box C1	0.128
Tead3	TEA domain family member 3	0.124
Shh	sonic hedgehog	0.119
Gata4	GATA binding protein 4	0.115
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.108
Sept7	septin 7	0.099
Amh	anti-Mullerian hormone	0.097
Hbb-b1	hemoglobin, beta adult major chain	0.096
Hoxd9	homeobox D9	0.096
Onecut1	one cut domain, family member 1	0.092
Pitx1	paired-like homeodomain transcription factor 1	0.092
Lmx1b	LIM homeobox transcription factor 1 beta	0.089
Pax3	paired box gene 3	0.087
Wnk2	WNK lysine deficient protein kinase 2	0.087
Hoxa11	homeobox A11	0.085
Wnt6	wingless-related MMTV integration site 6	0.084
Foxf1a	forkhead box F1a	0.084
Lhx1	LIM homeobox protein 1	0.084
Wnt2b	wingless related MMTV integration site 2b	0.083
Emid2	EMI domain containing 2	0.083
Gpr12	G-protein coupled receptor 12	0.081
Hif1a	hypoxia inducible factor 1, alpha subunit	0.080
Capn6	calpain 6	0.077
Ephb2	Eph receptor B2	0.074
Uncx	UNC homeobox	0.071
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.069
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.069
Pax2	paired box gene 2	0.065
Nhlh1	nescient helix loop helix 1	0.065
Nf1	neurofibromatosis 1	0.065
Myod1	myogenic differentiation 1	0.064
Rb1	retinoblastoma 1	0.064
Insr	insulin receptor	0.062
Rxra	retinoid X receptor alpha	0.061
Tac2	tachykinin 2	0.059
Pou3f2	POU domain, class 3, transcription factor 2	0.059
Des	desmin	0.058
Hoxa13	homeobox A13	0.058
Syt7	synaptotagmin VII	0.057
Tbx15	T-box 15	0.057
Psen1	presenilin 1	0.056
Tcfap2c	transcription factor AP-2, gamma	0.056
Hmx3	H6 homeobox 3	0.054
Braf	Braf transforming gene	0.052
Sall3	sal-like 3 (Drosophila)	0.051
Neurog1	neurogenin 1	0.050
Gata6	GATA binding protein 6	0.050
Hand2	heart and neural crest derivatives expressed transcript 2	0.050
Efna5	ephrin A5	0.050
Col4a3	collagen, type IV, alpha 3	0.049
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.048
Hmx1	H6 homeobox 1	0.047
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.047
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.047
Adra2b	adrenergic receptor, alpha 2b	0.047
Chrd	chordin	0.046
Wt1	Wilms tumor 1 homolog	0.044
Ebf3	early B-cell factor 3	0.044
Fgf3	fibroblast growth factor 3	0.044
Foxa2	forkhead box A2	0.044
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.043
Plcg1	phospholipase C, gamma 1	0.043
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.043
Fzd4	frizzled homolog 4 (Drosophila)	0.043
Pax8	paired box gene 8	0.042
Tcfap2a	transcription factor AP-2, alpha	0.042
Tbx1	T-box 1	0.041
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.041
Fgf4	fibroblast growth factor 4	0.041
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.040
Ihh	Indian hedgehog	0.040
Hand1	heart and neural crest derivatives expressed transcript 1	0.039
Nfia	nuclear factor I/A	0.039
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.037
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.037
Eya4	eyes absent 4 homolog (Drosophila)	0.037
Gpr27	G protein-coupled receptor 27	0.036
Hoxd11	homeobox D11	0.035
Tgfa	transforming growth factor alpha	0.034
Hoxc8	homeobox C8	0.034
Nrtn	neurturin	0.034
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.033
Hoxa10	homeobox A10	0.033
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.033
Epor	erythropoietin receptor	0.032
Arnt	aryl hydrocarbon receptor nuclear translocator	0.031
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.031
Clcnka	chloride channel Ka	0.031
Sox3	SRY-box containing gene 3	0.031
Plac1	placental specific protein 1	0.030
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.030
Cbln1	cerebellin 1 precursor protein	0.030
Rax	retina and anterior neural fold homeobox	0.030
Gsx1	GS homeobox 1	0.030
Msx1	homeobox, msh-like 1	0.030
Pitx3	paired-like homeodomain transcription factor 3	0.029
Foxb1	forkhead box B1	0.029
Tlx3	T-cell leukemia, homeobox 3	0.029
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.029
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.029
Lhx3	LIM homeobox protein 3	0.028
Sult5a1	sulfotransferase family 5A, member 1	0.028
Mipol1	mirror-image polydactyly gene 1 homolog (human)	0.028
Adra2a	adrenergic receptor, alpha 2a	0.028
Ret	ret proto-oncogene	0.028
Padi3	peptidyl arginine deiminase, type III	0.027
Lhx6	LIM homeobox protein 6	0.027
Hoxa4	homeobox A4	0.027
Zfp185	zinc finger protein 185	0.026
Hoxb1	homeobox B1	0.026
Hoxd3	homeobox D3	0.026
Mlph	melanophilin	0.025
Barx2	BarH-like homeobox 2	0.024
Wnt7a	wingless-related MMTV integration site 7A	0.024
Stat3	signal transducer and activator of transcription 3	0.024
Nrk	Nik related kinase	0.024
Grb10	growth factor receptor bound protein 10	0.023
Slc25a29	solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29	0.023
Hoxd10	homeobox D10	0.023
Zfp316	zinc finger protein 316	0.023
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.023
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.023
Fosl2	fos-like antigen 2	0.023
Neurog3	neurogenin 3	0.023
Ebf2	early B-cell factor 2	0.023
Sox7	SRY-box containing gene 7	0.022
Hoxa1	homeobox A1	0.022
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.022
Pou3f1	POU domain, class 3, transcription factor 1	0.022
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.022
Marveld3	MARVEL (membrane-associating) domain containing 3	0.022
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.022
Hoxc5	homeobox C5	0.022
Irx1	Iroquois related homeobox 1 (Drosophila)	0.021
Tal2	T-cell acute lymphocytic leukemia 2	0.021
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.021
Bmp7	bone morphogenetic protein 7	0.021
Pou3f3	POU domain, class 3, transcription factor 3	0.021
Evx2	even skipped homeotic gene 2 homolog	0.021
Irx6	Iroquois related homeobox 6 (Drosophila)	0.021
Cav1	caveolin 1, caveolae protein	0.021
Isl1	ISL1 transcription factor, LIM/homeodomain	0.021
Dab1	disabled homolog 1 (Drosophila)	0.021
Acan	aggrecan	0.020
Alk	anaplastic lymphoma kinase	0.020
Trpc5	transient receptor potential cation channel, subfamily C, member 5	0.020
Gcgr	glucagon receptor	0.020
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.020
Lhx5	LIM homeobox protein 5	0.020
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.019
Fgf10	fibroblast growth factor 10	0.019
Tgfbr3	transforming growth factor, beta receptor III	0.019
Hoxb9	homeobox B9	0.019
Dlg1	discs, large homolog 1 (Drosophila)	0.019
Hoxd4	homeobox D4	0.019
Tlx2	T-cell leukemia, homeobox 2	0.019
Ncs1	neuronal calcium sensor 1	0.019
Rbms1	RNA binding motif, single stranded interacting protein 1	0.019
Dlx4	distal-less homeobox 4	0.019
Flt1	FMS-like tyrosine kinase 1	0.019
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.019
Bnc1	basonuclin 1	0.019
Apc	adenomatosis polyposis coli	0.018
Pdx1	pancreatic and duodenal homeobox 1	0.018
Rdh10	retinol dehydrogenase 10 (all-trans)	0.018
Dlx6	distal-less homeobox 6	0.018
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.018
Twist2	twist homolog 2 (Drosophila)	0.018
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.018
Dcc	deleted in colorectal carcinoma	0.018
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.018
Pla2g2c	phospholipase A2, group IIC	0.018
Jag1	jagged 1	0.018
Phox2a	paired-like homeobox 2a	0.018
Itga3	integrin alpha 3	0.018
Ptk7	PTK7 protein tyrosine kinase 7	0.017
Smad3	MAD homolog 3 (Drosophila)	0.017
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.017
Nog	noggin	0.017
Actn3	actinin alpha 3	0.017
Lama5	laminin, alpha 5	0.017
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.017
Snx6	sorting nexin 6	0.017
Prkcc	protein kinase C, gamma	0.017
Chrm4	cholinergic receptor, muscarinic 4	0.017
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.017
Rab25	RAB25, member RAS oncogene family	0.017
Bzw1	basic leucine zipper and W2 domains 1	0.017
Cnr1	cannabinoid receptor 1 (brain)	0.017
Mmp24	matrix metallopeptidase 24	0.017
Sox11	SRY-box containing gene 11	0.017
Sh3pxd2a	SH3 and PX domains 2A	0.017
Wnt7b	wingless-related MMTV integration site 7B	0.016
Foxo4	forkhead box O4	0.016
En2	engrailed 2	0.016
Tbx2	T-box 2	0.016
Insm1	insulinoma-associated 1	0.016
Egln3	EGL nine homolog 3 (C. elegans)	0.016
Gnao1	guanine nucleotide binding protein, alpha O	0.016
Mgat3	mannoside acetylglucosaminyltransferase 3	0.016
Nptx2	neuronal pentraxin 2	0.016
Drd4	dopamine receptor D4	0.016
Ly6g6c	lymphocyte antigen 6 complex, locus G6C	0.016
Cachd1	cache domain containing 1	0.016
Fbn2	fibrillin 2	0.016
Notch2	Notch gene homolog 2 (Drosophila)	0.016
Vax1	ventral anterior homeobox containing gene 1	0.015
Nkx6-1	NK6 homeobox 1	0.015
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.015
Zfp651	zinc finger protein 651	0.015
Dlk1	delta-like 1 homolog (Drosophila)	0.015
Acr	acrosin prepropeptide	0.015
Hoxd8	homeobox D8	0.015
Msi1	Musashi homolog 1(Drosophila)	0.015
Tgfb2	transforming growth factor, beta 2	0.015
Eda	ectodysplasin-A	0.015
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.015
Ntsr1	neurotensin receptor 1	0.015
Sftpb	surfactant associated protein B	0.015
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.014
Gata2	GATA binding protein 2	0.014
Sox17	SRY-box containing gene 17	0.014
Wnt9a	wingless-type MMTV integration site 9A	0.014
Fgf15	fibroblast growth factor 15	0.014
Hrh3	histamine receptor H3	0.014
Lrp2	low density lipoprotein receptor-related protein 2	0.014
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.014
Inca1	inhibitor of CDK, cyclin A1 interacting protein 1	0.014
Cdh4	cadherin 4	0.014
Otx2	orthodenticle homolog 2 (Drosophila)	0.014
Grik3	glutamate receptor, ionotropic, kainate 3	0.014
Nrg3	neuregulin 3	0.014
Chad	chondroadherin	0.014
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.014
Pax1	paired box gene 1	0.013
Ccdc96	coiled-coil domain containing 96	0.013
P4htm	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	0.013
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.013
Ppard	peroxisome proliferator activator receptor delta	0.013
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.013
Rnf208	ring finger protein 208	0.013
Degs2	degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase	0.013
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.013
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.013
Sox1	SRY-box containing gene 1	0.013
Zbtb7c	zinc finger and BTB domain containing 7C	0.013
Nynrin	NYN domain and retroviral integrase containing	0.013
Lhb	luteinizing hormone beta	0.013
Dlx1	distal-less homeobox 1	0.013
Cdh3	cadherin 3	0.013
Mybph	myosin binding protein H	0.013
Myog	myogenin	0.013
Elf3	E74-like factor 3	0.013
Kcnk3	potassium channel, subfamily K, member 3	0.012
Pthlh	parathyroid hormone-like peptide	0.012
Lhx9	LIM homeobox protein 9	0.012
Hnf4a	hepatic nuclear factor 4, alpha	0.012
Adra2c	adrenergic receptor, alpha 2c	0.012
Notch1	Notch gene homolog 1 (Drosophila)	0.012
Pax7	paired box gene 7	0.012
Scn9a	sodium channel, voltage-gated, type IX, alpha	0.012
Hoxc6	homeobox C6	0.012
Foxc2	forkhead box C2	0.012
Gm13290	predicted gene 13290	0.012
Ppl	periplakin	0.012
Pou2f3	POU domain, class 2, transcription factor 3	0.012
Neurog2	neurogenin 2	0.012
Trp53	transformation related protein 53	0.012
Zic2	zinc finger protein of the cerebellum 2	0.012
Tmem116	transmembrane protein 116	0.012
Plxna1	plexin A1	0.012
Npr1	natriuretic peptide receptor 1	0.012
Masp1	mannan-binding lectin serine peptidase 1	0.012
Unc5c	unc-5 homolog C (C. elegans)	0.012
Ybx2	Y box protein 2	0.012
Tas1r2	taste receptor, type 1, member 2	0.012
Fam83h	family with sequence similarity 83, member H	0.012
Glra1	glycine receptor, alpha 1 subunit	0.011
Hoxd1	homeobox D1	0.011
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.011
Hrc	histidine rich calcium binding protein	0.011
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.011
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.011
Col1a1	collagen, type I, alpha 1	0.011
Tead4	TEA domain family member 4	0.011
Tnni1	troponin I, skeletal, slow 1	0.011
Vstm2b	V-set and transmembrane domain containing 2B	0.011
Pnmt	phenylethanolamine-N-methyltransferase	0.011
Etv2	ets variant gene 2	0.011
Zic1	zinc finger protein of the cerebellum 1	0.011
Tsga10	testis specific 10	0.011
Wnt4	wingless-related MMTV integration site 4	0.011
Foxo1	forkhead box O1	0.011
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.011
Nos1	nitric oxide synthase 1, neuronal	0.011
Wnt10b	wingless related MMTV integration site 10b	0.011
Myom2	myomesin 2	0.011
Csf3	colony stimulating factor 3 (granulocyte)	0.011
Ppara	peroxisome proliferator activated receptor alpha	0.011
Krtdap	keratinocyte differentiation associated protein	0.011
Rhox6	reproductive homeobox 6	0.011
Th	tyrosine hydroxylase	0.011
Tbx3	T-box 3	0.011
Pcdh12	protocadherin 12	0.011
Btbd17	BTB (POZ) domain containing 17	0.011
Sftpc	surfactant associated protein C	0.010
Cdx1	caudal type homeobox 1	0.010
Meox1	mesenchyme homeobox 1	0.010
Hoxb6	homeobox B6	0.010
Foxj1	forkhead box J1	0.010
Nrap	nebulin-related anchoring protein	0.010
Mark4	MAP/microtubule affinity-regulating kinase 4	0.010
Klf3	Kruppel-like factor 3 (basic)	0.010
Gja3	gap junction protein, alpha 3	0.010
Gpr132	G protein-coupled receptor 132	0.010
Kl	klotho	0.010