IMP

Process View

Mus musculus

4 genes annotated in mouse

Multi-species View

elastic fiber assembly

GO:0048251

Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "elastic fiber assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "elastic fiber assembly" (in gray)

Name	Description	Probability	Func Analog Organism
Eln	elastin	0.999
Tgfbr2	transforming growth factor, beta receptor II	0.999
Fbn1	fibrillin 1	0.995
Lox	lysyl oxidase	0.960
Igfbp6	insulin-like growth factor binding protein 6	0.647
Mmp2	matrix metallopeptidase 2	0.611
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.582
Tagln	transgelin	0.482
Agtr1a	angiotensin II receptor, type 1a	0.476
Ltbp2	latent transforming growth factor beta binding protein 2	0.470	Mouse
Tenc1	tensin like C1 domain-containing phosphatase	0.452
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.410
Sod3	superoxide dismutase 3, extracellular	0.405
Ldlr	low density lipoprotein receptor	0.315
Dpt	dermatopontin	0.303
Fbln5	fibulin 5	0.302
Cnn1	calponin 1	0.242
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.238	Mouse
Bgn	biglycan	0.237
Col6a1	collagen, type VI, alpha 1	0.225
Loxl1	lysyl oxidase-like 1	0.213	Mouse
Aoc3	amine oxidase, copper containing 3	0.211
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.208
Figf	c-fos induced growth factor	0.207
Thbs2	thrombospondin 2	0.203
Mrc2	mannose receptor, C type 2	0.199
Sorbs3	sorbin and SH3 domain containing 3	0.199
Col1a2	collagen, type I, alpha 2	0.194
Aebp1	AE binding protein 1	0.190
Col16a1	collagen, type XVI, alpha 1	0.186
Slc39a4	solute carrier family 39 (zinc transporter), member 4	0.182
Prelp	proline arginine-rich end leucine-rich repeat	0.165
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.149
Steap3	STEAP family member 3	0.144
Lama2	laminin, alpha 2	0.143
Col6a2	collagen, type VI, alpha 2	0.137
Lamb2	laminin, beta 2	0.134
Nid1	nidogen 1	0.133
Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.130
Apoe	apolipoprotein E	0.129
Egfl7	EGF-like domain 7	0.125
Acta2	actin, alpha 2, smooth muscle, aorta	0.113
Thbs3	thrombospondin 3	0.098
Idua	iduronidase, alpha-L-	0.087
Fbln2	fibulin 2	0.082	Mouse
Pcolce	procollagen C-endopeptidase enhancer protein	0.080
Mcam	melanoma cell adhesion molecule	0.075
Mfap5	microfibrillar associated protein 5	0.074
Sox13	SRY-box containing gene 13	0.070
Acvrl1	activin A receptor, type II-like 1	0.070
Slit3	slit homolog 3 (Drosophila)	0.068
Mrvi1	MRV integration site 1	0.066
Col6a3	collagen, type VI, alpha 3	0.064
Timp3	tissue inhibitor of metalloproteinase 3	0.064
Dpep1	dipeptidase 1 (renal)	0.060
Ptrf	polymerase I and transcript release factor	0.060
Ltbp4	latent transforming growth factor beta binding protein 4	0.057	Mouse
Notch3	Notch gene homolog 3 (Drosophila)	0.057
Chrm2	cholinergic receptor, muscarinic 2, cardiac	0.056
Nos3	nitric oxide synthase 3, endothelial cell	0.054
Htra3	HtrA serine peptidase 3	0.054
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.049
Tgfbr1	transforming growth factor, beta receptor I	0.048
Thbd	thrombomodulin	0.047
Cyr61	cysteine rich protein 61	0.047
Ctgf	connective tissue growth factor	0.046
Agtr2	angiotensin II receptor, type 2	0.046
Cfd	complement factor D (adipsin)	0.043
Itgbl1	integrin, beta-like 1	0.043
Cd248	CD248 antigen, endosialin	0.043
Pdlim3	PDZ and LIM domain 3	0.043
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.042
Adamts2	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2	0.041
Mylk	myosin, light polypeptide kinase	0.041
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.040
Ptgis	prostaglandin I2 (prostacyclin) synthase	0.040
Lamc2	laminin, gamma 2	0.040
Ddr2	discoidin domain receptor family, member 2	0.039
Col4a5	collagen, type IV, alpha 5	0.039
Lama5	laminin, alpha 5	0.039
Gas1	growth arrest specific 1	0.037
Smtn	smoothelin	0.036
Itgb4	integrin beta 4	0.036
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.034
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.034
Smoc2	SPARC related modular calcium binding 2	0.033
Upk3b	uroplakin 3B	0.033
Mfap4	microfibrillar-associated protein 4	0.033
Tnxb	tenascin XB	0.032	Human
Trim47	tripartite motif-containing 47	0.032
Fmod	fibromodulin	0.031
Myh11	myosin, heavy polypeptide 11, smooth muscle	0.031	Human
Slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	0.030
Srpx2	sushi-repeat-containing protein, X-linked 2	0.030
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.030
Lamb1	laminin B1	0.028
Msln	mesothelin	0.028
Chpf	chondroitin polymerizing factor	0.028
Cav1	caveolin 1, caveolae protein	0.027
Col4a2	collagen, type IV, alpha 2	0.027
Col5a1	collagen, type V, alpha 1	0.027
Actg2	actin, gamma 2, smooth muscle, enteric	0.027
Col1a1	collagen, type I, alpha 1	0.027
Igfbp7	insulin-like growth factor binding protein 7	0.027
Slc31a1	solute carrier family 31, member 1	0.027
Nes	nestin	0.026
Timp1	tissue inhibitor of metalloproteinase 1	0.026
Adamts5	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)	0.026
Col8a1	collagen, type VIII, alpha 1	0.026
Emp2	epithelial membrane protein 2	0.026
Amotl2	angiomotin-like 2	0.026
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.025
Gpr133	G protein-coupled receptor 133	0.025
Mgp	matrix Gla protein	0.025
Scara3	scavenger receptor class A, member 3	0.023
Tgfb3	transforming growth factor, beta 3	0.023
Cilp	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	0.023
Col5a2	collagen, type V, alpha 2	0.023
Spsb1	splA/ryanodine receptor domain and SOCS box containing 1	0.023
Thbs1	thrombospondin 1	0.022
Slc12a4	solute carrier family 12, member 4	0.022
Lrp1	low density lipoprotein receptor-related protein 1	0.022
Plin4	perilipin 4	0.022
Robo4	roundabout homolog 4 (Drosophila)	0.021
Pbxip1	pre-B-cell leukemia transcription factor interacting protein 1	0.021
Col15a1	collagen, type XV, alpha 1	0.021
Rhbdf1	rhomboid family 1 (Drosophila)	0.021
Flt4	FMS-like tyrosine kinase 4	0.020
Cbr2	carbonyl reductase 2	0.020
Pkd1	polycystic kidney disease 1 homolog	0.020
Phldb1	pleckstrin homology-like domain, family B, member 1	0.020
Bmp6	bone morphogenetic protein 6	0.020
Kcnk3	potassium channel, subfamily K, member 3	0.020
Gjc1	gap junction protein, gamma 1	0.019
Vasn	vasorin	0.018
Gm10393	predicted gene 10393	0.018
Lmcd1	LIM and cysteine-rich domains 1	0.018
Tmem45a	transmembrane protein 45a	0.018
Itga7	integrin alpha 7	0.017
Htra1	HtrA serine peptidase 1	0.017
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.017
Tusc5	tumor suppressor candidate 5	0.017
Ushbp1	Usher syndrome 1C binding protein 1	0.017
Igfbp3	insulin-like growth factor binding protein 3	0.016
Abi3bp	ABI gene family, member 3 (NESH) binding protein	0.016
Prss23	protease, serine, 23	0.016
Cxcr7	chemokine (C-X-C motif) receptor 7	0.016
Scarf2	scavenger receptor class F, member 2	0.016
Clec3b	C-type lectin domain family 3, member b	0.016
Mmp23	matrix metallopeptidase 23	0.016
Fgd5	FYVE, RhoGEF and PH domain containing 5	0.016
Tnc	tenascin C	0.016
Podn	podocan	0.016
Osr1	odd-skipped related 1 (Drosophila)	0.016
Col4a1	collagen, type IV, alpha 1	0.016
Adcy4	adenylate cyclase 4	0.016
Lmod1	leiomodin 1 (smooth muscle)	0.016
Fmo2	flavin containing monooxygenase 2	0.015
Galntl2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2	0.015
Col3a1	collagen, type III, alpha 1	0.015
Chrnb1	cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)	0.015
Fstl1	follistatin-like 1	0.015
Chrm3	cholinergic receptor, muscarinic 3, cardiac	0.015
Olfml2b	olfactomedin-like 2B	0.015
Snta1	syntrophin, acidic 1	0.015
Mmp3	matrix metallopeptidase 3	0.015
Fblim1	filamin binding LIM protein 1	0.015
Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.015
Dmpk	dystrophia myotonica-protein kinase	0.015
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.015
Fibin	fin bud initiation factor homolog (zebrafish)	0.014
C1qtnf2	C1q and tumor necrosis factor related protein 2	0.014
Xirp1	xin actin-binding repeat containing 1	0.014
Ltbp1	latent transforming growth factor beta binding protein 1	0.014	Mouse
Phldb2	pleckstrin homology-like domain, family B, member 2	0.014
A4galt	alpha 1,4-galactosyltransferase	0.014
Myl9	myosin, light polypeptide 9, regulatory	0.014
Sulf1	sulfatase 1	0.014
Mybpc3	myosin binding protein C, cardiac	0.013
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.013
AU021092	expressed sequence AU021092	0.013
Syde1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.013
BC020535	cDNA sequence BC020535	0.013
Npr3	natriuretic peptide receptor 3	0.013
Cpxm2	carboxypeptidase X 2 (M14 family)	0.013
Efcab4a	EF-hand calcium binding domain 4A	0.013
Mustn1	musculoskeletal, embryonic nuclear protein 1	0.013
Tgfbr3	transforming growth factor, beta receptor III	0.012
Erbb2ip	Erbb2 interacting protein	0.012
C1qtnf7	C1q and tumor necrosis factor related protein 7	0.012
Fgfr1	fibroblast growth factor receptor 1	0.012
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.012
Pmepa1	prostate transmembrane protein, androgen induced 1	0.012
Sardh	sarcosine dehydrogenase	0.012
Pecam1	platelet/endothelial cell adhesion molecule 1	0.012
Ephx3	epoxide hydrolase 3	0.012
Hspa12b	heat shock protein 12B	0.012
Gpx3	glutathione peroxidase 3	0.012
Creb3l1	cAMP responsive element binding protein 3-like 1	0.012
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.011
Olfml2a	olfactomedin-like 2A	0.011
Sh3bgr	SH3-binding domain glutamic acid-rich protein	0.011
Gas6	growth arrest specific 6	0.011
Rhoj	ras homolog gene family, member J	0.011
Ephb4	Eph receptor B4	0.011
Cygb	cytoglobin	0.011
Marveld1	MARVEL (membrane-associating) domain containing 1	0.011
Des	desmin	0.011
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.011
Synm	synemin, intermediate filament protein	0.011
Tnn	tenascin N	0.011
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.010
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.010
Kcne4	potassium voltage-gated channel, Isk-related subfamily, gene 4	0.010
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.010
Dhrs7c	dehydrogenase/reductase (SDR family) member 7C	0.010
Tlr4	toll-like receptor 4	0.010
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.010
Esam	endothelial cell-specific adhesion molecule	0.010