IMP

Process View

Mus musculus

12 genes annotated in mouse

astrocyte development

The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "astrocyte development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "astrocyte development" (in gray)

Name	Description	Probability	Func Analog Organism
Pax3	paired box gene 3	0.836
Pax2	paired box gene 2	0.751
Emx2	empty spiracles homolog 2 (Drosophila)	0.691
Otx2	orthodenticle homolog 2 (Drosophila)	0.652
Isl1	ISL1 transcription factor, LIM/homeodomain	0.643
Shh	sonic hedgehog	0.635
Eya1	eyes absent 1 homolog (Drosophila)	0.628
Pnpla2	patatin-like phospholipase domain containing 2	0.592
Sall4	sal-like 4 (Drosophila)	0.542
Drd2	dopamine receptor D2	0.476
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.456
Sox2	SRY-box containing gene 2	0.441
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.422
Nanog	Nanog homeobox	0.415
Kl	klotho	0.385
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.369
Fgf8	fibroblast growth factor 8	0.347
Fgfr2	fibroblast growth factor receptor 2	0.329
Gli3	GLI-Kruppel family member GLI3	0.323
Pax6	paired box gene 6	0.266
Nog	noggin	0.264
Sall3	sal-like 3 (Drosophila)	0.261
Nefl	neurofilament, light polypeptide	0.242	Mouse
Des	desmin	0.230	Mouse
Adrb3	adrenergic receptor, beta 3	0.219	Mouse
Adrb1	adrenergic receptor, beta 1	0.213	Mouse
Sall1	sal-like 1 (Drosophila)	0.210
Sox9	SRY-box containing gene 9	0.207
Foxg1	forkhead box G1	0.203
Msx1	homeobox, msh-like 1	0.187
Tcfap2a	transcription factor AP-2, alpha	0.178
Bmp4	bone morphogenetic protein 4	0.176
Pparg	peroxisome proliferator activated receptor gamma	0.174
Rarg	retinoic acid receptor, gamma	0.160
Tcfcp2l1	transcription factor CP2-like 1	0.159
Sox10	SRY-box containing gene 10	0.158
Sox1	SRY-box containing gene 1	0.154
Lepr	leptin receptor	0.151
Gbx2	gastrulation brain homeobox 2	0.140
Ret	ret proto-oncogene	0.139
Fgf10	fibroblast growth factor 10	0.132
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.128
Chd7	chromodomain helicase DNA binding protein 7	0.123
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.116
Wnt7a	wingless-related MMTV integration site 7A	0.105
Insm1	insulinoma-associated 1	0.102
Dlx5	distal-less homeobox 5	0.102
Atoh7	atonal homolog 7 (Drosophila)	0.094
Pax1	paired box gene 1	0.093
Lmx1a	LIM homeobox transcription factor 1 alpha	0.091
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.082
Sult4a1	sulfotransferase family 4A, member 1	0.081
Bdnf	brain derived neurotrophic factor	0.080
Rxra	retinoid X receptor alpha	0.078
Hmx3	H6 homeobox 3	0.078
Hoxb1	homeobox B1	0.077
Foxd2	forkhead box D2	0.076
Rara	retinoic acid receptor, alpha	0.075
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.075
Tbx10	T-box 10	0.074
Hoxd3	homeobox D3	0.074
Ppl	periplakin	0.074
Fgf4	fibroblast growth factor 4	0.073
Tbx1	T-box 1	0.072
Gli2	GLI-Kruppel family member GLI2	0.068
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.065
Chrd	chordin	0.064
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.064
Plcg1	phospholipase C, gamma 1	0.063
Fgf3	fibroblast growth factor 3	0.063
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.062
Neurog3	neurogenin 3	0.062
Wt1	Wilms tumor 1 homolog	0.061
C1ql1	complement component 1, q subcomponent-like 1	0.059
Hand2	heart and neural crest derivatives expressed transcript 2	0.059
Nid1	nidogen 1	0.059
Crp	C-reactive protein, pentraxin-related	0.058
Wnt1	wingless-related MMTV integration site 1	0.056
Hoxa1	homeobox A1	0.056
Nf1	neurofibromatosis 1	0.055
Vav2	vav 2 oncogene	0.055
Vegfa	vascular endothelial growth factor A	0.055
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.054
Zeb1	zinc finger E-box binding homeobox 1	0.054
Vangl2	vang-like 2 (van gogh, Drosophila)	0.053
ND6	NADH dehydrogenase subunit 6	0.052
Ednra	endothelin receptor type A	0.052
Apoa1	apolipoprotein A-I	0.051
Ar	androgen receptor	0.050
Esrrb	estrogen related receptor, beta	0.049
Agtr1a	angiotensin II receptor, type 1a	0.049
Sox3	SRY-box containing gene 3	0.048
Mog	myelin oligodendrocyte glycoprotein	0.048
Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	0.047	Mouse
Dlx1	distal-less homeobox 1	0.047
Hoxd11	homeobox D11	0.046
F9	coagulation factor IX	0.046
En1	engrailed 1	0.045
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.044
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.043
Nos1	nitric oxide synthase 1, neuronal	0.042
Pitx2	paired-like homeodomain transcription factor 2	0.042
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.041
Cplx1	complexin 1	0.041
Apoe	apolipoprotein E	0.041
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.041
Fgfr1	fibroblast growth factor receptor 1	0.040
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.040
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.039
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.038
Mobp	myelin-associated oligodendrocytic basic protein	0.038
Bdkrb2	bradykinin receptor, beta 2	0.038
Adrb2	adrenergic receptor, beta 2	0.038	Mouse
Phox2b	paired-like homeobox 2b	0.038
Neurod1	neurogenic differentiation 1	0.037
Lef1	lymphoid enhancer binding factor 1	0.036
Prox1	prospero-related homeobox 1	0.036
Foxc2	forkhead box C2	0.036
Otx1	orthodenticle homolog 1 (Drosophila)	0.036
Gsx1	GS homeobox 1	0.036
Gfap	glial fibrillary acidic protein	0.035
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.035	Mouse
Fga	fibrinogen alpha chain	0.035
Grid1	glutamate receptor, ionotropic, delta 1	0.034
Zic2	zinc finger protein of the cerebellum 2	0.034
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.034
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.034
T	brachyury	0.033
Foxi3	forkhead box I3	0.033
Sstr4	somatostatin receptor 4	0.033
Zic3	zinc finger protein of the cerebellum 3	0.033
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.032
Nefm	neurofilament, medium polypeptide	0.032	Mouse
Vip	vasoactive intestinal polypeptide	0.032
Gdnf	glial cell line derived neurotrophic factor	0.032
Ptch1	patched homolog 1	0.032
Tcof1	Treacher Collins Franceschetti syndrome 1, homolog	0.031
Inhbc	inhibin beta-C	0.031
Lhx1	LIM homeobox protein 1	0.031
Prkcc	protein kinase C, gamma	0.031
Shc3	src homology 2 domain-containing transforming protein C3	0.030
Trp63	transformation related protein 63	0.030
Kifc2	kinesin family member C2	0.030
Prph	peripherin	0.029	Mouse
Hoxa4	homeobox A4	0.029
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.029
Hpca	hippocalcin	0.029
Ece1	endothelin converting enzyme 1	0.028
Glra1	glycine receptor, alpha 1 subunit	0.028
Lag3	lymphocyte-activation gene 3	0.028
Cfh	complement component factor h	0.028
Lama5	laminin, alpha 5	0.027
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.027
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.026
Amh	anti-Mullerian hormone	0.026
Adcyap1	adenylate cyclase activating polypeptide 1	0.026
Ppt1	palmitoyl-protein thioesterase 1	0.026
Apoa5	apolipoprotein A-V	0.026
Hoxa10	homeobox A10	0.025
Sox11	SRY-box containing gene 11	0.025
Tlx3	T-cell leukemia, homeobox 3	0.025
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.025
Pou3f2	POU domain, class 3, transcription factor 2	0.024
Spry4	sprouty homolog 4 (Drosophila)	0.024
Pou3f1	POU domain, class 3, transcription factor 1	0.024	Mouse
Gdf11	growth differentiation factor 11	0.024
Dlx6	distal-less homeobox 6	0.024
F2	coagulation factor II	0.024
Cckbr	cholecystokinin B receptor	0.024
Epha8	Eph receptor A8	0.024
Ren1	renin 1 structural	0.024
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.023	Mouse
Gpr50	G-protein-coupled receptor 50	0.023
Phox2a	paired-like homeobox 2a	0.023
2210010C04Rik	RIKEN cDNA 2210010C04 gene	0.023
Dlx2	distal-less homeobox 2	0.023
Trh	thyrotropin releasing hormone	0.023
Hoxc5	homeobox C5	0.023
Napb	N-ethylmaleimide sensitive fusion protein attachment protein beta	0.023
Plp1	proteolipid protein (myelin) 1	0.022
Ache	acetylcholinesterase	0.022
Stx1b	syntaxin 1B	0.022
Emid2	EMI domain containing 2	0.022
Crhr1	corticotropin releasing hormone receptor 1	0.022
Cnr1	cannabinoid receptor 1 (brain)	0.022
Jph3	junctophilin 3	0.022
Hmx1	H6 homeobox 1	0.021
Msx2	homeobox, msh-like 2	0.021
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.021
Tacr1	tachykinin receptor 1	0.021
Grm2	glutamate receptor, metabotropic 2	0.021
Hoxc8	homeobox C8	0.021
Ncan	neurocan	0.021
Mta1	metastasis associated 1	0.021
Npy2r	neuropeptide Y receptor Y2	0.020
Slc12a1	solute carrier family 12, member 1	0.020
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.020
Prrx1	paired related homeobox 1	0.020
Sstr1	somatostatin receptor 1	0.020
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.020
Braf	Braf transforming gene	0.020
Ep400	E1A binding protein p400	0.020
Gpm6b	glycoprotein m6b	0.020	Mouse
Ngf	nerve growth factor	0.020
Hoxc4	homeobox C4	0.020
Pde6b	phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide	0.020
Sst	somatostatin	0.019
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.019
Mmp24	matrix metallopeptidase 24	0.019
Wnt6	wingless-related MMTV integration site 6	0.019
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.019
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.019
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.019
Hoxa11	homeobox A11	0.019
Elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.018
Dmgdh	dimethylglycine dehydrogenase precursor	0.018
Nptx2	neuronal pentraxin 2	0.018
Alx3	aristaless-like homeobox 3	0.018
Syt6	synaptotagmin VI	0.018
Vax1	ventral anterior homeobox containing gene 1	0.018
En2	engrailed 2	0.018
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.018
Neurog1	neurogenin 1	0.018
Hoxb8	homeobox B8	0.018
Agtr2	angiotensin II receptor, type 2	0.018
Gjb1	gap junction protein, beta 1	0.018
Gatad2b	GATA zinc finger domain containing 2B	0.017
Ugt8a	UDP galactosyltransferase 8A	0.017
A2m	alpha-2-macroglobulin	0.017
Rb1	retinoblastoma 1	0.017
Sox4	SRY-box containing gene 4	0.017
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.017
Lama1	laminin, alpha 1	0.017
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.017	Mouse
Hand1	heart and neural crest derivatives expressed transcript 1	0.017
Adora2a	adenosine A2a receptor	0.017	Rat
Npy5r	neuropeptide Y receptor Y5	0.017
Apc	adenomatosis polyposis coli	0.017
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.017
Wnt3	wingless-related MMTV integration site 3	0.017
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.016
Ncam2	neural cell adhesion molecule 2	0.016
Igfbpl1	insulin-like growth factor binding protein-like 1	0.016
Ntn4	netrin 4	0.016	Mouse
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.016
Hes5	hairy and enhancer of split 5 (Drosophila)	0.016
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.016
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.016
Ang2	angiogenin, ribonuclease A family, member 2	0.016
Cst3	cystatin C	0.016
Pou3f3	POU domain, class 3, transcription factor 3	0.016	Mouse
Sim1	single-minded homolog 1 (Drosophila)	0.016
Sebox	SEBOX homeobox	0.016
Sync	syncoilin	0.016	Mouse
Bcl2	B-cell leukemia/lymphoma 2	0.016
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.015
Hoxd4	homeobox D4	0.015
Ahsg	alpha-2-HS-glycoprotein	0.015
Rarb	retinoic acid receptor, beta	0.015
Plg	plasminogen	0.015
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.015
Igfbp1	insulin-like growth factor binding protein 1	0.015
Ndn	necdin	0.015
Tenc1	tensin like C1 domain-containing phosphatase	0.015
Ctnnb1	catenin (cadherin associated protein), beta 1	0.015
Nefh	neurofilament, heavy polypeptide	0.015	Mouse
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.015
Gjb5	gap junction protein, beta 5	0.015
Apof	apolipoprotein F	0.015
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.015
Alx4	aristaless-like homeobox 4	0.015
Fgf6	fibroblast growth factor 6	0.014
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.014
Adra2c	adrenergic receptor, alpha 2c	0.014	Mouse
S1pr2	sphingosine-1-phosphate receptor 2	0.014
Hoxb9	homeobox B9	0.014
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.014
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.014
Foxd3	forkhead box D3	0.014
Hoxa2	homeobox A2	0.014
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.014
Pou4f2	POU domain, class 4, transcription factor 2	0.014	Mouse
Nrsn1	neurensin 1	0.014
Onecut1	one cut domain, family member 1	0.014
Gabra2	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2	0.014
Nppc	natriuretic peptide type C	0.014
Tgfbr3	transforming growth factor, beta receptor III	0.014
Olig3	oligodendrocyte transcription factor 3	0.014
Bmp7	bone morphogenetic protein 7	0.014
Syt9	synaptotagmin IX	0.014
Hoxa3	homeobox A3	0.014
Ednrb	endothelin receptor type B	0.013
Ikzf4	IKAROS family zinc finger 4	0.013
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.013
Gja5	gap junction protein, alpha 5	0.013
Atoh1	atonal homolog 1 (Drosophila)	0.013
Hoxd1	homeobox D1	0.013
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.013
Nos3	nitric oxide synthase 3, endothelial cell	0.013
Ptafr	platelet-activating factor receptor	0.013
Plau	plasminogen activator, urokinase	0.013
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.013
Khdc1b	KH domain containing 1B	0.013
Zfp92	zinc finger protein 92	0.013
Uncx	UNC homeobox	0.013
Fmnl1	formin-like 1	0.012
Gng3	guanine nucleotide binding protein (G protein), gamma 3	0.012
Hoxb5	homeobox B5	0.012
Gsc	goosecoid homeobox	0.012
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.012
D17H6S56E-3	DNA segment, Chr 17, human D6S56E 3	0.012
Lhx6	LIM homeobox protein 6	0.012
C3	complement component 3	0.012
Nacc1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	0.012
Neurog2	neurogenin 2	0.012
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.012
Foxc1	forkhead box C1	0.012
Saa4	serum amyloid A 4	0.012
Col4a1	collagen, type IV, alpha 1	0.012
Fut2	fucosyltransferase 2	0.012
Gcg	glucagon	0.012
Osmr	oncostatin M receptor	0.012
Alx1	ALX homeobox 1	0.012
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.012
Mitf	microphthalmia-associated transcription factor	0.011
Rln1	relaxin 1	0.011
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.011
Klk6	kallikrein related-peptidase 6	0.011
Wnt7b	wingless-related MMTV integration site 7B	0.011
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.011
Galr1	galanin receptor 1	0.011
Dpf1	D4, zinc and double PHD fingers family 1	0.011
Il11	interleukin 11	0.011
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.011
Atp4b	ATPase, H+/K+ exchanging, beta polypeptide	0.011
Btbd17	BTB (POZ) domain containing 17	0.011
Emx1	empty spiracles homolog 1 (Drosophila)	0.011
Sh3bgrl3	SH3 domain binding glutamic acid-rich protein-like 3	0.011
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.011
Efnb2	ephrin B2	0.011
Cbln1	cerebellin 1 precursor protein	0.011
Gata3	GATA binding protein 3	0.011
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.011
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.011
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.011	Mouse
Edn1	endothelin 1	0.011
Dlx4	distal-less homeobox 4	0.011
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.011
Sox21	SRY-box containing gene 21	0.011
Vav3	vav 3 oncogene	0.011
Lmna	lamin A	0.011
Gucy2e	guanylate cyclase 2e	0.011
Btn1a1	butyrophilin, subfamily 1, member A1	0.011
Bsn	bassoon	0.011
Rxrg	retinoid X receptor gamma	0.011
Crip2	cysteine rich protein 2	0.011
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.011
Alk	anaplastic lymphoma kinase	0.010
Fgf18	fibroblast growth factor 18	0.010
Jag1	jagged 1	0.010
Nppb	natriuretic peptide type B	0.010
Elf4	E74-like factor 4 (ets domain transcription factor)	0.010
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.010
Wnt10b	wingless related MMTV integration site 10b	0.010
Tnp2	transition protein 2	0.010
Cntn2	contactin 2	0.010
Foxd1	forkhead box D1	0.010
Oprd1	opioid receptor, delta 1	0.010
Fezf2	Fez family zinc finger 2	0.010
Ina	internexin neuronal intermediate filament protein, alpha	0.010	Mouse
Psmd4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.010
Crygc	crystallin, gamma C	0.010
Hoxb4	homeobox B4	0.010
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.010
Kcnd1	potassium voltage-gated channel, Shal-related family, member 1	0.010
Eda	ectodysplasin-A	0.010
Krtdap	keratinocyte differentiation associated protein	0.010
Msx3	homeobox, msh-like 3	0.010