IMP

Process View

Mus musculus

4 genes annotated in mouse

regulation of sarcomere organization

Any process that modulates the rate, frequency or extent myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of sarcomere organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of sarcomere organization" (in gray)

Name	Description	Probability	Func Analog Organism
Hdac4	histone deacetylase 4	0.790
Sin3a	transcriptional regulator, SIN3A (yeast)	0.653
Hdac5	histone deacetylase 5	0.615
Mef2c	myocyte enhancer factor 2C	0.582
Hrc	histidine rich calcium binding protein	0.443
Arid1a	AT rich interactive domain 1A (SWI-like)	0.242
Actn2	actinin alpha 2	0.211
Myl3	myosin, light polypeptide 3	0.208
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.206
Ldb3	LIM domain binding 3	0.205
Sox2	SRY-box containing gene 2	0.185
Zfp932	zinc finger protein 932	0.172
Myom2	myomesin 2	0.159
Csrp3	cysteine and glycine-rich protein 3	0.157
Tnnc2	troponin C2, fast	0.140
Mta2	metastasis-associated gene family, member 2	0.139
Myl1	myosin, light polypeptide 1	0.128
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.126
Cox8b	cytochrome c oxidase, subunit VIIIb	0.117
Myoz1	myozenin 1	0.115
Mef2d	myocyte enhancer factor 2D	0.115	Mouse
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.114
Myom1	myomesin 1	0.110
Tnnt3	troponin T3, skeletal, fast	0.108
Ckm	creatine kinase, muscle	0.102
Tnni2	troponin I, skeletal, fast 2	0.098
Nrap	nebulin-related anchoring protein	0.095
Suv39h1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.091
Cox6a2	cytochrome c oxidase, subunit VI a, polypeptide 2	0.090
Ednrb	endothelin receptor type B	0.081
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.078
Pgam2	phosphoglycerate mutase 2	0.076
Tcf4	transcription factor 4	0.074
Myh8	myosin, heavy polypeptide 8, skeletal muscle, perinatal	0.074
Art1	ADP-ribosyltransferase 1	0.073
Mybph	myosin binding protein H	0.072
Ebf2	early B-cell factor 2	0.071
Ttn	titin	0.070
Ednra	endothelin receptor type A	0.070
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.065
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.064
Qk	quaking	0.063
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.062
Zeb2	zinc finger E-box binding homeobox 2	0.062
Actc1	actin, alpha, cardiac muscle 1	0.062
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.060	Mouse
Spnb2	spectrin beta 2	0.060
Kif1b	kinesin family member 1B	0.058
Apobec2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2	0.056
Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.055
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.055
Prkce	protein kinase C, epsilon	0.054
Casq2	calsequestrin 2	0.053
Hdac7	histone deacetylase 7	0.053
Snrk	SNF related kinase	0.052
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.051
Ckmt2	creatine kinase, mitochondrial 2	0.049
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.049
Kdm5b	lysine (K)-specific demethylase 5B	0.049
Hdac9	histone deacetylase 9	0.048
Txlnb	taxilin beta	0.047
Myf6	myogenic factor 6	0.047
Tgfb2	transforming growth factor, beta 2	0.045
Trdn	triadin	0.045
Myoz2	myozenin 2	0.045
Rbbp7	retinoblastoma binding protein 7	0.042
Ctbp1	C-terminal binding protein 1	0.042
Fbxo32	F-box protein 32	0.041
Lmod2	leiomodin 2 (cardiac)	0.039
Srpk3	serine/arginine-rich protein specific kinase 3	0.038
Ryr1	ryanodine receptor 1, skeletal muscle	0.037
Xirp1	xin actin-binding repeat containing 1	0.036
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.035
Foxc1	forkhead box C1	0.035
Myh7	myosin, heavy polypeptide 7, cardiac muscle, beta	0.035	Mouse
Anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.034
Phkg1	phosphorylase kinase gamma 1	0.033
Parp1	poly (ADP-ribose) polymerase family, member 1	0.033
Plxna2	plexin A2	0.032
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.032
Myl7	myosin, light polypeptide 7, regulatory	0.031
Tcfcp2l1	transcription factor CP2-like 1	0.030
Casq1	calsequestrin 1	0.030
Acta1	actin, alpha 1, skeletal muscle	0.028
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.028
Myh2	myosin, heavy polypeptide 2, skeletal muscle, adult	0.028
Tnnc1	troponin C, cardiac/slow skeletal	0.026
Trim54	tripartite motif-containing 54	0.026
Vldlr	very low density lipoprotein receptor	0.026
Eya1	eyes absent 1 homolog (Drosophila)	0.026
Neurod1	neurogenic differentiation 1	0.026
Smpx	small muscle protein, X-linked	0.026
Scn10a	sodium channel, voltage-gated, type X, alpha	0.025
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.025
Sall4	sal-like 4 (Drosophila)	0.024
Zbtb20	zinc finger and BTB domain containing 20	0.024
Tnnt2	troponin T2, cardiac	0.024
Gata6	GATA binding protein 6	0.023
Fyn	Fyn proto-oncogene	0.023
Cav3	caveolin 3	0.022
Prkacb	protein kinase, cAMP dependent, catalytic, beta	0.022
Prrx1	paired related homeobox 1	0.022
Tnni3	troponin I, cardiac 3	0.022
Nfix	nuclear factor I/X	0.022
Mecp2	methyl CpG binding protein 2	0.021
Gsc	goosecoid homeobox	0.021
Zmynd11	zinc finger, MYND domain containing 11	0.021
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.020
Ncor2	nuclear receptor co-repressor 2	0.020
Actn3	actinin alpha 3	0.020
Ntf3	neurotrophin 3	0.020
Klf7	Kruppel-like factor 7 (ubiquitous)	0.020
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.020
Rbbp4	retinoblastoma binding protein 4	0.019
Clec3b	C-type lectin domain family 3, member b	0.019
Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.019
Epha4	Eph receptor A4	0.019
Mta1	metastasis associated 1	0.019
Fli1	Friend leukemia integration 1	0.019
Gucy1a3	guanylate cyclase 1, soluble, alpha 3	0.018
Fzd4	frizzled homolog 4 (Drosophila)	0.018
Flt1	FMS-like tyrosine kinase 1	0.018
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.018
Popdc3	popeye domain containing 3	0.018
Myot	myotilin	0.018
Rora	RAR-related orphan receptor alpha	0.018
Angpt1	angiopoietin 1	0.018
Kcnj2	potassium inwardly-rectifying channel, subfamily J, member 2	0.018
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.017
Tnnt1	troponin T1, skeletal, slow	0.017
Etl4	enhancer trap locus 4	0.017
Nfia	nuclear factor I/A	0.017
Tal1	T-cell acute lymphocytic leukemia 1	0.017
Ece1	endothelin converting enzyme 1	0.017
Tcap	titin-cap	0.017
Rxrg	retinoid X receptor gamma	0.016
Nfic	nuclear factor I/C	0.016
Dnmt1	DNA methyltransferase (cytosine-5) 1	0.016
Rab12	RAB12, member RAS oncogene family	0.016
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.016
Efnb2	ephrin B2	0.015
Gsk3b	glycogen synthase kinase 3 beta	0.015
Dtna	dystrobrevin alpha	0.015
Hspa1l	heat shock protein 1-like	0.015
Camk2d	calcium/calmodulin-dependent protein kinase II, delta	0.015
Pbx1	pre B-cell leukemia transcription factor 1	0.015
Ptprb	protein tyrosine phosphatase, receptor type, B	0.015
Apex1	apurinic/apyrimidinic endonuclease 1	0.015
Ryr2	ryanodine receptor 2, cardiac	0.015
Hfe2	hemochromatosis type 2 (juvenile) (human homolog)	0.015
Chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)	0.015
Lmod3	leiomodin 3 (fetal)	0.015
Vegfa	vascular endothelial growth factor A	0.015
Mitf	microphthalmia-associated transcription factor	0.015
Prkg1	protein kinase, cGMP-dependent, type I	0.015
Mylpf	myosin light chain, phosphorylatable, fast skeletal muscle	0.014
Pthlh	parathyroid hormone-like peptide	0.014
Nppa	natriuretic peptide type A	0.014
Hmgn1	high mobility group nucleosomal binding domain 1	0.014
BC051019	cDNA sequence BC051019	0.014
Ccnd1	cyclin D1	0.014
Mbnl1	muscleblind-like 1 (Drosophila)	0.014
Cast	calpastatin	0.014
Rpl3l	ribosomal protein L3-like	0.014
Nanog	Nanog homeobox	0.014
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.014
Rgs5	regulator of G-protein signaling 5	0.014
Rtn2	reticulon 2 (Z-band associated protein)	0.014
Dusp1	dual specificity phosphatase 1	0.014
Crhr2	corticotropin releasing hormone receptor 2	0.013
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.013
Pygm	muscle glycogen phosphorylase	0.013
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.013
Epha3	Eph receptor A3	0.013
Hspb2	heat shock protein 2	0.013
Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	0.013
Sh3bp5	SH3-domain binding protein 5 (BTK-associated)	0.013
Pkia	protein kinase inhibitor, alpha	0.013
Ttc3	tetratricopeptide repeat domain 3	0.013
Celf2	CUGBP, Elav-like family member 2	0.013
Eid1	EP300 interacting inhibitor of differentiation 1	0.013
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.013
Kitl	kit ligand	0.013
Cdk14	cyclin-dependent kinase 14	0.013
Des	desmin	0.013
Nfib	nuclear factor I/B	0.013
Ebf1	early B-cell factor 1	0.012
Sh3glb1	SH3-domain GRB2-like B1 (endophilin)	0.012
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.012
Hand2	heart and neural crest derivatives expressed transcript 2	0.012
Mybbp1a	MYB binding protein (P160) 1a	0.012
Brd7	bromodomain containing 7	0.012
Itgb1bp2	integrin beta 1 binding protein 2	0.012
Anapc5	anaphase-promoting complex subunit 5	0.012
Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.012
Clec1b	C-type lectin domain family 1, member b	0.012
Zeb1	zinc finger E-box binding homeobox 1	0.012
Plp1	proteolipid protein (myelin) 1	0.012
Cap2	CAP, adenylate cyclase-associated protein, 2 (yeast)	0.012
Isl1	ISL1 transcription factor, LIM/homeodomain	0.012
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.012
Bmp5	bone morphogenetic protein 5	0.012
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.012
Fign	fidgetin	0.012
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.012
Rai2	retinoic acid induced 2	0.012
Slco5a1	solute carrier organic anion transporter family, member 5A1	0.012
Ncoa1	nuclear receptor coactivator 1	0.012
Hist4h4	histone cluster 4, H4	0.011
Fbxw7	F-box and WD-40 domain protein 7	0.011
Bach2	BTB and CNC homology 2	0.011
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.011
Klhdc2	kelch domain containing 2	0.011
Art3	ADP-ribosyltransferase 3	0.011
Gpr133	G protein-coupled receptor 133	0.011
Bche	butyrylcholinesterase	0.011
Pcdh7	protocadherin 7	0.011
Pja2	praja 2, RING-H2 motif containing	0.011
Bhlhb9	basic helix-loop-helix domain containing, class B9	0.011
Tet1	tet oncogene 1	0.011
Foxp1	forkhead box P1	0.011
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.011
Ube2d1	ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog (yeast)	0.011
Gja5	gap junction protein, alpha 5	0.011
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.011
Limch1	LIM and calponin homology domains 1	0.011
Npc1	Niemann Pick type C1	0.011
Cpd	carboxypeptidase D	0.011
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.011
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.011
Synpo2l	synaptopodin 2-like	0.011
Ipo4	importin 4	0.011
Fkbp3	FK506 binding protein 3	0.011
Gpm6b	glycoprotein m6b	0.011
Abcc8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.011
Phb2	prohibitin 2	0.011
Rhob	ras homolog gene family, member B	0.010
Ppara	peroxisome proliferator activated receptor alpha	0.010
Clip1	CAP-GLY domain containing linker protein 1	0.010
Shox2	short stature homeobox 2	0.010
Capn3	calpain 3	0.010
Murc	muscle-related coiled-coil protein	0.010
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.010
Pfkm	phosphofructokinase, muscle	0.010
Scn7a	sodium channel, voltage-gated, type VII, alpha	0.010
Rbm24	RNA binding motif protein 24	0.010
Fgb	fibrinogen beta chain	0.010
Dcpp1	demilune cell and parotid protein 1	0.010
Zfpm2	zinc finger protein, multitype 2	0.010
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.010
Gcap14	granule cell antiserum positive 14	0.010
2310002L09Rik	RIKEN cDNA 2310002L09 gene	0.010
Pten	phosphatase and tensin homolog	0.010
Kcnk3	potassium channel, subfamily K, member 3	0.010
Atp1a2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	0.010
Csnk1e	casein kinase 1, epsilon	0.010
Sox5	SRY-box containing gene 5	0.010