IMP

Process View

Mus musculus

1 genes annotated in mouse

renal capsule morphogenesis

The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "renal capsule morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "renal capsule morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Foxc1	forkhead box C1	0.996	Mouse
Pax2	paired box gene 2	0.991
Tbx1	T-box 1	0.987
Bmp4	bone morphogenetic protein 4	0.983
Fgfr2	fibroblast growth factor receptor 2	0.975
Foxc2	forkhead box C2	0.971	Mouse
Fgf8	fibroblast growth factor 8	0.968
Pitx2	paired-like homeodomain transcription factor 2	0.949
Gli3	GLI-Kruppel family member GLI3	0.933
Hoxa1	homeobox A1	0.925
Otx2	orthodenticle homolog 2 (Drosophila)	0.904
Eya1	eyes absent 1 homolog (Drosophila)	0.889
Tcfap2a	transcription factor AP-2, alpha	0.849
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.840
Pax3	paired box gene 3	0.828
Hmx3	H6 homeobox 3	0.797
Foxa2	forkhead box A2	0.795	Mouse
Pax6	paired box gene 6	0.769
Gbx2	gastrulation brain homeobox 2	0.764
Hand2	heart and neural crest derivatives expressed transcript 2	0.699
Hand1	heart and neural crest derivatives expressed transcript 1	0.661
Msx1	homeobox, msh-like 1	0.636
Jag1	jagged 1	0.537
Lmx1b	LIM homeobox transcription factor 1 beta	0.515
Pax8	paired box gene 8	0.488
Foxg1	forkhead box G1	0.467	Mouse
Hoxd3	homeobox D3	0.429
Dlx5	distal-less homeobox 5	0.412
Tgfb2	transforming growth factor, beta 2	0.388
Nog	noggin	0.365
Hoxd11	homeobox D11	0.346
Otx1	orthodenticle homolog 1 (Drosophila)	0.342
Msx2	homeobox, msh-like 2	0.332
Rarb	retinoic acid receptor, beta	0.315
Lmx1a	LIM homeobox transcription factor 1 alpha	0.312
Vangl2	vang-like 2 (van gogh, Drosophila)	0.290
Gata4	GATA binding protein 4	0.289
Pax9	paired box gene 9	0.275
Foxa1	forkhead box A1	0.270	Mouse
Prrx1	paired related homeobox 1	0.259
Nkx2-1	NK2 homeobox 1	0.259
Fgfr3	fibroblast growth factor receptor 3	0.250
T	brachyury	0.247
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.233
Bmp7	bone morphogenetic protein 7	0.227
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.214
Hoxd9	homeobox D9	0.213
Gdnf	glial cell line derived neurotrophic factor	0.209
Foxf2	forkhead box F2	0.201
Nkx3-2	NK3 homeobox 2	0.196
Lhx1	LIM homeobox protein 1	0.192
Fgf3	fibroblast growth factor 3	0.178
Cdx1	caudal type homeobox 1	0.174
Gsc	goosecoid homeobox	0.164
Hoxa3	homeobox A3	0.160
Pdx1	pancreatic and duodenal homeobox 1	0.153
Hoxa2	homeobox A2	0.150
Meox2	mesenchyme homeobox 2	0.143
Neurog1	neurogenin 1	0.136
Cldn3	claudin 3	0.129
Efnb2	ephrin B2	0.121
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.121
En1	engrailed 1	0.120
Ihh	Indian hedgehog	0.120
Gli2	GLI-Kruppel family member GLI2	0.116
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.115
Hoxa10	homeobox A10	0.115
Chd7	chromodomain helicase DNA binding protein 7	0.114
Sox2	SRY-box containing gene 2	0.113
Mesp1	mesoderm posterior 1	0.113
Hoxa9	homeobox A9	0.111
Matn3	matrilin 3	0.110
Bnc1	basonuclin 1	0.110
Wt1	Wilms tumor 1 homolog	0.109
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.106
Psen1	presenilin 1	0.106
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.105
Hoxd10	homeobox D10	0.100
Hoxb6	homeobox B6	0.100
Vax1	ventral anterior homeobox containing gene 1	0.099
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.098
Chrd	chordin	0.096
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.096
Amh	anti-Mullerian hormone	0.094
Vegfa	vascular endothelial growth factor A	0.092
Foxh1	forkhead box H1	0.092
Evx2	even skipped homeotic gene 2 homolog	0.091
Wnt1	wingless-related MMTV integration site 1	0.090
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.089
Isl1	ISL1 transcription factor, LIM/homeodomain	0.081
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.078
Elf3	E74-like factor 3	0.078
Sox9	SRY-box containing gene 9	0.077
Pax1	paired box gene 1	0.075
Hoxc8	homeobox C8	0.074
Lrp2	low density lipoprotein receptor-related protein 2	0.072
Cldn8	claudin 8	0.071
Hoxa4	homeobox A4	0.069
Tbx10	T-box 10	0.069
Gata6	GATA binding protein 6	0.068
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.066
Pou4f2	POU domain, class 4, transcription factor 2	0.065
Fgf4	fibroblast growth factor 4	0.063
Hmx1	H6 homeobox 1	0.061
Rb1	retinoblastoma 1	0.061
Dmrt3	doublesex and mab-3 related transcription factor 3	0.061
Tcf21	transcription factor 21	0.060
Pitx3	paired-like homeodomain transcription factor 3	0.060
Fgfr1	fibroblast growth factor receptor 1	0.058
Phlda2	pleckstrin homology-like domain, family A, member 2	0.056
Dhh	desert hedgehog	0.054
Prrx2	paired related homeobox 2	0.052
Adra2b	adrenergic receptor, alpha 2b	0.052
Ctnnb1	catenin (cadherin associated protein), beta 1	0.052
Hoxc6	homeobox C6	0.051
Bik	BCL2-interacting killer	0.050
Smo	smoothened homolog (Drosophila)	0.050
Hoxb8	homeobox B8	0.050
Snai1	snail homolog 1 (Drosophila)	0.050
Runx2	runt related transcription factor 2	0.048
Foxb1	forkhead box B1	0.048
Emid2	EMI domain containing 2	0.047
Hoxb5	homeobox B5	0.047
Pthlh	parathyroid hormone-like peptide	0.046
Rarg	retinoic acid receptor, gamma	0.046
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.046
Hoxb3	homeobox B3	0.046
Cldn2	claudin 2	0.045
Sox3	SRY-box containing gene 3	0.045
Cnga3	cyclic nucleotide gated channel alpha 3	0.044
Emx2	empty spiracles homolog 2 (Drosophila)	0.044
Emx1	empty spiracles homolog 1 (Drosophila)	0.044
Gjd3	gap junction protein, delta 3	0.044
Cldn4	claudin 4	0.044
Hoxb13	homeobox B13	0.043
Tmprss2	transmembrane protease, serine 2	0.043
Irx1	Iroquois related homeobox 1 (Drosophila)	0.042
Hoxa11	homeobox A11	0.042
Ppl	periplakin	0.041
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.040
Pitx1	paired-like homeodomain transcription factor 1	0.039
Hoxd4	homeobox D4	0.039
4930504O13Rik	RIKEN cDNA 4930504O13 gene	0.039
Pcdh12	protocadherin 12	0.039
Twist2	twist homolog 2 (Drosophila)	0.038
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.037
Hoxd13	homeobox D13	0.037
Klk4	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	0.036
Mlph	melanophilin	0.036
Egfr	epidermal growth factor receptor	0.036
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.035
Atoh1	atonal homolog 1 (Drosophila)	0.035
Ntf3	neurotrophin 3	0.034
Col13a1	collagen, type XIII, alpha 1	0.034
Foxd4	forkhead box D4	0.033	Mouse
Gsx1	GS homeobox 1	0.033
Mecom	MDS1 and EVI1 complex locus	0.033
Hoxb9	homeobox B9	0.032
Lefty1	left right determination factor 1	0.032
Sftpb	surfactant associated protein B	0.032
Pigr	polymeric immunoglobulin receptor	0.032
Sox7	SRY-box containing gene 7	0.032
Ednra	endothelin receptor type A	0.032
Zic3	zinc finger protein of the cerebellum 3	0.032
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.032
Figla	folliculogenesis specific basic helix-loop-helix	0.031
Zeb1	zinc finger E-box binding homeobox 1	0.031
Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	0.031
G6pc2	glucose-6-phosphatase, catalytic, 2	0.031
Olfr70	olfactory receptor 70	0.030
Hoxd1	homeobox D1	0.030
Hoxd8	homeobox D8	0.030
Alx4	aristaless-like homeobox 4	0.029
Foxi1	forkhead box I1	0.029	Mouse
Fzd10	frizzled homolog 10 (Drosophila)	0.029
Col4a3	collagen, type IV, alpha 3	0.029
Nrtn	neurturin	0.029
Gata3	GATA binding protein 3	0.029
Tas1r1	taste receptor, type 1, member 1	0.029
Hoxb1	homeobox B1	0.028
BC057022	cDNA sequence BC057022	0.028
Kremen2	kringle containing transmembrane protein 2	0.028
F12	coagulation factor XII (Hageman factor)	0.028
Wnt5b	wingless-related MMTV integration site 5B	0.028
Nobox	NOBOX oogenesis homeobox	0.028
Tbx2	T-box 2	0.028
Tmem30b	transmembrane protein 30B	0.027
Alx1	ALX homeobox 1	0.027
Etv2	ets variant gene 2	0.027
Upk3b	uroplakin 3B	0.027
Foxn1	forkhead box N1	0.027
Nodal	nodal	0.026
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.026
Hnf1b	HNF1 homeobox B	0.025
Gja1	gap junction protein, alpha 1	0.025
Il11	interleukin 11	0.025
Ocln	occludin	0.025
Vgll2	vestigial like 2 homolog (Drosophila)	0.025
Myod1	myogenic differentiation 1	0.024
Fgf21	fibroblast growth factor 21	0.024
Hmx2	H6 homeobox 2	0.024
Wnt7a	wingless-related MMTV integration site 7A	0.024
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.024
Sall4	sal-like 4 (Drosophila)	0.024
Tbx15	T-box 15	0.024
Cldn6	claudin 6	0.024
Fam83h	family with sequence similarity 83, member H	0.024
Krtcap3	keratinocyte associated protein 3	0.024
Crb3	crumbs homolog 3 (Drosophila)	0.023
Plg	plasminogen	0.023
Rab17	RAB17, member RAS oncogene family	0.023
Sim2	single-minded homolog 2 (Drosophila)	0.023
Evx1	even skipped homeotic gene 1 homolog	0.023
Rnf186	ring finger protein 186	0.023
Tal2	T-cell acute lymphocytic leukemia 2	0.023
Wfdc2	WAP four-disulfide core domain 2	0.022
Tead3	TEA domain family member 3	0.022
2610109H07Rik	RIKEN cDNA 2610109H07 gene	0.022
Kcnj15	potassium inwardly-rectifying channel, subfamily J, member 15	0.022
Zfp185	zinc finger protein 185	0.021
Tlx3	T-cell leukemia, homeobox 3	0.021
Gpr50	G-protein-coupled receptor 50	0.021
Cdh1	cadherin 1	0.021
Rax	retina and anterior neural fold homeobox	0.021
Fgfr4	fibroblast growth factor receptor 4	0.020
Afp	alpha fetoprotein	0.020
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.020
Gdf15	growth differentiation factor 15	0.020
Miox	myo-inositol oxygenase	0.020
Hnf4a	hepatic nuclear factor 4, alpha	0.020
Pou4f3	POU domain, class 4, transcription factor 3	0.020
Ctf1	cardiotrophin 1	0.020
Pou2f3	POU domain, class 2, transcription factor 3	0.020
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.019
Foxd3	forkhead box D3	0.019	Mouse
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.019
BC021891	cDNA sequence BC021891	0.019
Ptk7	PTK7 protein tyrosine kinase 7	0.019
Rdh10	retinol dehydrogenase 10 (all-trans)	0.019
Il25	interleukin 25	0.019
Rxra	retinoid X receptor alpha	0.019
Tcl1	T-cell lymphoma breakpoint 1	0.018
Tgfbr2	transforming growth factor, beta receptor II	0.018
Gjb5	gap junction protein, beta 5	0.018
Nccrp1	non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)	0.018
Myf5	myogenic factor 5	0.018
Hoxb2	homeobox B2	0.018
Mycs	myc-like oncogene, s-myc protein	0.018
Sp5	trans-acting transcription factor 5	0.018
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.018
Hoxb7	homeobox B7	0.017
Pbx1	pre B-cell leukemia transcription factor 1	0.017
Onecut1	one cut domain, family member 1	0.017
Wnt3a	wingless-related MMTV integration site 3A	0.017
Tlx2	T-cell leukemia, homeobox 2	0.017
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.017
Col4a4	collagen, type IV, alpha 4	0.017
Cldn7	claudin 7	0.017
BC021785	cDNA sequence BC021785	0.017
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.017
Col8a2	collagen, type VIII, alpha 2	0.017
Smad6	MAD homolog 6 (Drosophila)	0.017
Fgf10	fibroblast growth factor 10	0.017
Hoxa5	homeobox A5	0.016
Tbx3	T-box 3	0.016
Ttll9	tubulin tyrosine ligase-like family, member 9	0.016
Sh3pxd2a	SH3 and PX domains 2A	0.016
Epn3	epsin 3	0.016
Hs3st3a1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.016
Tcfap2c	transcription factor AP-2, gamma	0.016
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.016
Slc44a4	solute carrier family 44, member 4	0.016
Prr7	proline rich 7 (synaptic)	0.015
Lyzl4	lysozyme-like 4	0.015
Kcnk7	potassium channel, subfamily K, member 7	0.015
Aqp2	aquaporin 2	0.015
Hif3a	hypoxia inducible factor 3, alpha subunit	0.015
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.015
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.015
Sox13	SRY-box containing gene 13	0.015
Sall3	sal-like 3 (Drosophila)	0.015
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.015
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.015
Cdx2	caudal type homeobox 2	0.015
Hmga2	high mobility group AT-hook 2	0.015
Ptch1	patched homolog 1	0.015
Crygn	crystallin, gamma N	0.014
Skor1	SKI family transcriptional corepressor 1	0.014
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.014
Dlx2	distal-less homeobox 2	0.014
Col17a1	collagen, type XVII, alpha 1	0.014
Bhlha9	basic helix-loop-helix family, member a9	0.014
Irx3	Iroquois related homeobox 3 (Drosophila)	0.014
Sox1	SRY-box containing gene 1	0.014
Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	0.014
Krt7	keratin 7	0.014
Mep1a	meprin 1 alpha	0.014
Col22a1	collagen, type XXII, alpha 1	0.014
Krt15	keratin 15	0.014
Ltc4s	leukotriene C4 synthase	0.014
Cdh3	cadherin 3	0.014
Tmem217	transmembrane protein 217	0.014
Nkx6-3	NK6 homeobox 3	0.014
Fzd8	frizzled homolog 8 (Drosophila)	0.014
Marveld3	MARVEL (membrane-associating) domain containing 3	0.013
Apoa5	apolipoprotein A-V	0.013
Mdfi	MyoD family inhibitor	0.013
Bmp2	bone morphogenetic protein 2	0.013
Prss8	protease, serine, 8 (prostasin)	0.013
Lhb	luteinizing hormone beta	0.013
Foxq1	forkhead box Q1	0.013	Mouse
Wnt2b	wingless related MMTV integration site 2b	0.013
Fam65c	family with sequence similarity 65, member C	0.013
Cldn27	claudin 27	0.013
Cel	carboxyl ester lipase	0.013
Fscn2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.013
Flt4	FMS-like tyrosine kinase 4	0.013
Fshb	follicle stimulating hormone beta	0.013
Ly6g6d	lymphocyte antigen 6 complex, locus G6D	0.013
Gjb3	gap junction protein, beta 3	0.012
Phox2b	paired-like homeobox 2b	0.012
Neurog3	neurogenin 3	0.012
Inca1	inhibitor of CDK, cyclin A1 interacting protein 1	0.012
Clec18a	C-type lectin domain family 18, member A	0.012
Hes1	hairy and enhancer of split 1 (Drosophila)	0.012
Gdf7	growth differentiation factor 7	0.012
Btbd17	BTB (POZ) domain containing 17	0.012
Rassf10	Ras association (RalGDS/AF-6) domain family (N-terminal) member 10	0.012
Hoxb4	homeobox B4	0.012
Vax2	ventral anterior homeobox containing gene 2	0.012
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.012
Ptgfr	prostaglandin F receptor	0.012
Hmga1	high mobility group AT-hook 1	0.012
Cdx4	caudal type homeobox 4	0.012
Lhx5	LIM homeobox protein 5	0.012
4933405L10Rik	RIKEN cDNA 4933405L10 gene	0.012
Wnt6	wingless-related MMTV integration site 6	0.012
C77080	expressed sequence C77080	0.012
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.012
Gjb4	gap junction protein, beta 4	0.012
Arid3c	AT rich interactive domain 3C (BRIGHT-like)	0.012
Sim1	single-minded homolog 1 (Drosophila)	0.012
Lrp6	low density lipoprotein receptor-related protein 6	0.012
Gyltl1b	glycosyltransferase-like 1B	0.012
4930404N11Rik	RIKEN cDNA 4930404N11 gene	0.011
Shroom1	shroom family member 1	0.011
Plac1	placental specific protein 1	0.011
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.011
Col2a1	collagen, type II, alpha 1	0.011
Prm1	protamine 1	0.011
Hes5	hairy and enhancer of split 5 (Drosophila)	0.011
Krt8	keratin 8	0.011
Rhcg	Rhesus blood group-associated C glycoprotein	0.011
Dhrsx	dehydrogenase/reductase (SDR family) X chromosome	0.011
Neurog2	neurogenin 2	0.011
Mip	major intrinsic protein of eye lens fiber	0.011
Mafa	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)	0.011
Myog	myogenin	0.011
Sost	sclerostin	0.011
Ehf	ets homologous factor	0.011
Slc22a19	solute carrier family 22 (organic anion transporter), member 19	0.011
Gcm1	glial cells missing homolog 1 (Drosophila)	0.011
Kl	klotho	0.011
Gabrp	gamma-aminobutyric acid (GABA) A receptor, pi	0.011
Zfp771	zinc finger protein 771	0.011
Klf5	Kruppel-like factor 5	0.011
Rgs9bp	regulator of G-protein signalling 9 binding protein	0.011
Myl7	myosin, light polypeptide 7, regulatory	0.011
Esrp2	epithelial splicing regulatory protein 2	0.011
Dusp9	dual specificity phosphatase 9	0.010
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.010
Degs2	degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase	0.010
Apoc1	apolipoprotein C-I	0.010
Adm2	adrenomedullin 2	0.010
Iqcd	IQ motif containing D	0.010
Zic1	zinc finger protein of the cerebellum 1	0.010
Mapk13	mitogen-activated protein kinase 13	0.010
Cryga	crystallin, gamma A	0.010
Rbmxl2	RNA binding motif protein, X-linked-like 2	0.010
Grb7	growth factor receptor bound protein 7	0.010
Rab25	RAB25, member RAS oncogene family	0.010
Spdef	SAM pointed domain containing ets transcription factor	0.010
Scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.010
Onecut3	one cut domain, family member 3	0.010
BC051019	cDNA sequence BC051019	0.010